Mus musculus

96 known processes

Unc13a

unc-13 homolog A (C. elegans)

(Aliases: 2410078G03Rik,C630025L14,Munc13-1)

Unc13a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.076
cation homeostasis GO:0055080 212 0.057
dendrite development GO:0016358 115 0.054
purine nucleotide metabolic process GO:0006163 302 0.050
ribonucleoside metabolic process GO:0009119 245 0.050
chemotaxis GO:0006935 247 0.047
Worm
regulation of ion transport GO:0043269 215 0.045
ras protein signal transduction GO:0007265 77 0.045
nuclear division GO:0000280 158 0.044
synaptic transmission GO:0007268 329 0.043
locomotory behavior GO:0007626 195 0.042
organelle localization GO:0051640 179 0.041
metal ion homeostasis GO:0055065 189 0.041
cellular amino acid metabolic process GO:0006520 103 0.041
amine metabolic process GO:0009308 45 0.041
multicellular organismal signaling GO:0035637 91 0.040
regulation of ion transmembrane transport GO:0034765 119 0.039
muscle system process GO:0003012 141 0.039
cell adhesion GO:0007155 329 0.039
cellular ketone metabolic process GO:0042180 84 0.038
sensory perception GO:0007600 245 0.038
small gtpase mediated signal transduction GO:0007264 97 0.038
regulation of organelle organization GO:0033043 289 0.038
cellular ion homeostasis GO:0006873 165 0.037
purine containing compound metabolic process GO:0072521 311 0.036
regulation of cytokine production GO:0001817 266 0.036
regulation of hydrolase activity GO:0051336 246 0.036
establishment of vesicle localization GO:0051650 81 0.035
regulation of neuron differentiation GO:0045664 281 0.035
intracellular protein transport GO:0006886 204 0.035
endomembrane system organization GO:0010256 147 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.034
g protein coupled receptor signaling pathway GO:0007186 243 0.034
response to radiation GO:0009314 165 0.033
cellular homeostasis GO:0019725 240 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.032
regulation of neuron projection development GO:0010975 169 0.031
organophosphate catabolic process GO:0046434 232 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
transmission of nerve impulse GO:0019226 76 0.030
organelle fission GO:0048285 170 0.030
synaptic vesicle transport GO:0048489 57 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
nucleoside catabolic process GO:0009164 206 0.029
exocytosis GO:0006887 121 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.029
rho protein signal transduction GO:0007266 32 0.029
carbohydrate derivative catabolic process GO:1901136 231 0.028
carbohydrate metabolic process GO:0005975 230 0.028
cell type specific apoptotic process GO:0097285 268 0.028
protein localization to membrane GO:0072657 108 0.028
gtp metabolic process GO:0046039 144 0.027
neuronal action potential GO:0019228 54 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
cytoplasmic transport GO:0016482 234 0.027
nucleotide metabolic process GO:0009117 332 0.027
regulation of membrane potential GO:0042391 192 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
cellular amine metabolic process GO:0044106 44 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
purine nucleotide catabolic process GO:0006195 211 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.026
regulation of homeostatic process GO:0032844 182 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
nucleoside triphosphate catabolic process GO:0009143 205 0.025
vesicle localization GO:0051648 86 0.025
ribonucleotide catabolic process GO:0009261 208 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
actin cytoskeleton organization GO:0030036 220 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
immune effector process GO:0002252 321 0.025
heterocycle catabolic process GO:0046700 280 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.024
peptidyl amino acid modification GO:0018193 336 0.024
muscle contraction GO:0006936 101 0.024
regulation of purine nucleotide metabolic process GO:1900542 169 0.024
cognition GO:0050890 149 0.024
regulation of cell projection organization GO:0031344 206 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
cytokine production GO:0001816 319 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
positive regulation of nervous system development GO:0051962 221 0.023
central nervous system neuron differentiation GO:0021953 162 0.023
microtubule based process GO:0007017 236 0.023
cation transport GO:0006812 399 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
organelle assembly GO:0070925 177 0.023
camera type eye development GO:0043010 266 0.023
divalent inorganic cation homeostasis GO:0072507 138 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
regulation of system process GO:0044057 200 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
cellular metal ion homeostasis GO:0006875 151 0.022
retina development in camera type eye GO:0060041 119 0.022
endocytosis GO:0006897 168 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
transmembrane transport GO:0055085 412 0.022
macromolecule catabolic process GO:0009057 281 0.022
aromatic compound catabolic process GO:0019439 286 0.021
sensory organ morphogenesis GO:0090596 242 0.021
cellular protein complex assembly GO:0043623 116 0.021
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
dephosphorylation GO:0016311 129 0.021
axonogenesis GO:0007409 274 0.021
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
muscle tissue development GO:0060537 308 0.020
nucleotide catabolic process GO:0009166 217 0.020
microtubule based movement GO:0007018 84 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
nitrogen compound transport GO:0071705 271 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.019
protein maturation GO:0051604 176 0.019
neurotransmitter secretion GO:0007269 62 0.019
apoptotic signaling pathway GO:0097190 306 0.019
heart process GO:0003015 94 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
regulation of ras protein signal transduction GO:0046578 114 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
response to organonitrogen compound GO:0010243 246 0.019
neurotransmitter transport GO:0006836 76 0.018
calcium ion homeostasis GO:0055074 127 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
protein processing GO:0016485 163 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
cation transmembrane transport GO:0098655 266 0.018
developmental maturation GO:0021700 193 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
adult behavior GO:0030534 135 0.018
regulation of exocytosis GO:0017157 61 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
rhythmic process GO:0048511 174 0.018
guanosine containing compound catabolic process GO:1901069 144 0.018
regulation of neurotransmitter levels GO:0001505 87 0.018
blood circulation GO:0008015 195 0.017
membrane organization GO:0061024 245 0.017
anatomical structure homeostasis GO:0060249 145 0.017
smooth muscle contraction GO:0006939 44 0.017
calcium ion dependent exocytosis GO:0017156 35 0.017
nucleoside metabolic process GO:0009116 246 0.017
regulation of proteolysis GO:0030162 164 0.017
photoreceptor cell differentiation GO:0046530 52 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
striated muscle contraction GO:0006941 45 0.017
cell chemotaxis GO:0060326 81 0.017
circulatory system process GO:0003013 197 0.017
regulation of intracellular transport GO:0032386 159 0.017
compound eye development GO:0048749 1 0.017
mitotic cell cycle GO:0000278 195 0.017
regulation of mapk cascade GO:0043408 248 0.016
skeletal muscle organ development GO:0060538 163 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
membrane depolarization during sa node cell action potential GO:0086046 2 0.016
acetylcholine secretion neurotransmission GO:0014055 2 0.016
purine containing compound catabolic process GO:0072523 213 0.016
regulation of anatomical structure size GO:0090066 178 0.016
mapk cascade GO:0000165 281 0.016
neuron apoptotic process GO:0051402 142 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
protein polymerization GO:0051258 57 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
cytosolic calcium ion homeostasis GO:0051480 70 0.016
neural tube development GO:0021915 160 0.016
regulation of cell cycle GO:0051726 281 0.016
ion transmembrane transport GO:0034220 361 0.016
hindbrain development GO:0030902 128 0.016
cellular potassium ion transport GO:0071804 43 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
protein localization to organelle GO:0033365 185 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
negative regulation of nervous system development GO:0051961 156 0.016
negative regulation of immune system process GO:0002683 209 0.016
muscle cell differentiation GO:0042692 261 0.016
protein modification by small protein conjugation GO:0032446 187 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
cellular chemical homeostasis GO:0055082 215 0.015
negative regulation of organelle organization GO:0010639 90 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
regulation of blood pressure GO:0008217 93 0.015
meiotic nuclear division GO:0007126 115 0.015
multi multicellular organism process GO:0044706 109 0.015
Worm
response to organic cyclic compound GO:0014070 198 0.015
t cell activation GO:0042110 289 0.015
eye photoreceptor cell differentiation GO:0001754 41 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
adult walking behavior GO:0007628 41 0.015
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.015
divalent inorganic cation transport GO:0072511 178 0.015
regulation of defense response GO:0031347 233 0.015
mitochondrion distribution GO:0048311 4 0.015
regulation of feeding behavior GO:0060259 3 0.015
Worm
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.015
myeloid leukocyte differentiation GO:0002573 119 0.014
microtubule based transport GO:0010970 50 0.014
spermatogenesis GO:0007283 284 0.014
synaptic vesicle localization GO:0097479 59 0.014
cerebellar purkinje cell layer development GO:0021680 26 0.014
leukocyte migration GO:0050900 124 0.014
sa node cell action potential GO:0086015 4 0.014
axon cargo transport GO:0008088 33 0.014
myotube differentiation GO:0014902 105 0.014
negative regulation of molecular function GO:0044092 258 0.014
blood vessel morphogenesis GO:0048514 285 0.014
sensory perception of sound GO:0007605 97 0.014
positive regulation of cell death GO:0010942 224 0.014
cell recognition GO:0008037 83 0.014
establishment of synaptic vesicle localization GO:0097480 57 0.014
protein catabolic process GO:0030163 221 0.014
protein targeting GO:0006605 143 0.014
gliogenesis GO:0042063 141 0.014
regulation of hormone levels GO:0010817 211 0.014
learning or memory GO:0007611 148 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
amide transport GO:0042886 138 0.014
anion transport GO:0006820 177 0.014
actin filament organization GO:0007015 113 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
muscle cell development GO:0055001 133 0.014
establishment of organelle localization GO:0051656 122 0.014
sensory perception of touch GO:0050975 2 0.013
lateral inhibition GO:0046331 1 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
acetylcholine transport GO:0015870 2 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
myeloid leukocyte migration GO:0097529 57 0.013
positive regulation of protein modification process GO:0031401 299 0.013
positive regulation of necrotic cell death GO:0010940 1 0.013
actin polymerization or depolymerization GO:0008154 54 0.013
positive regulation of secretion GO:0051047 130 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
regulation of multi organism process GO:0043900 111 0.013
Worm
feeding behavior GO:0007631 62 0.013
Worm
sequestering of calcium ion GO:0051208 18 0.013
myeloid cell differentiation GO:0030099 233 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
neuron death GO:0070997 154 0.013
metencephalon development GO:0022037 89 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
regulation of synaptic plasticity GO:0048167 87 0.013
amino acid transport GO:0006865 61 0.013
fat cell differentiation GO:0045444 160 0.013
gtp catabolic process GO:0006184 143 0.012
action potential GO:0001508 78 0.012
neuromuscular process controlling balance GO:0050885 59 0.012
regulation of endocytosis GO:0030100 69 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
maintenance of location GO:0051235 89 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
acetate ester transport GO:1901374 2 0.012
peptide transport GO:0015833 133 0.012
mrna metabolic process GO:0016071 84 0.012
neuron projection guidance GO:0097485 141 0.012
Worm
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
cell division GO:0051301 120 0.012
dna metabolic process GO:0006259 303 0.012
homeostasis of number of cells GO:0048872 210 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
regulation of cell motility GO:2000145 236 0.012
activation of immune response GO:0002253 138 0.012
maintenance of presynaptic active zone structure GO:0048790 1 0.012
leukocyte differentiation GO:0002521 342 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
regulation of transferase activity GO:0051338 263 0.012
synapse organization GO:0050808 125 0.012
meiotic cell cycle GO:0051321 122 0.012
response to extracellular stimulus GO:0009991 127 0.012
multicellular organism growth GO:0035264 161 0.012
positive regulation of cell development GO:0010720 237 0.012
positive regulation of organelle organization GO:0010638 128 0.012
cell growth GO:0016049 130 0.012
regulation of protein kinase activity GO:0045859 232 0.012
oocyte construction GO:0007308 2 0.012
rna processing GO:0006396 105 0.012
positive regulation of gtp catabolic process GO:0033126 85 0.012
actin filament polymerization GO:0030041 44 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
skeletal system development GO:0001501 356 0.012
regulation of heart contraction GO:0008016 77 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
regulation of cell activation GO:0050865 289 0.011
detection of abiotic stimulus GO:0009582 60 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
glucose metabolic process GO:0006006 92 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
regulation of secretion by cell GO:1903530 249 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
regulation of transporter activity GO:0032409 57 0.011
organic acid transport GO:0015849 101 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
regulation of cell cycle process GO:0010564 160 0.011
carboxylic acid transport GO:0046942 100 0.011
axon ensheathment GO:0008366 76 0.011
neuron migration GO:0001764 122 0.011
oocyte axis specification GO:0007309 2 0.011
detection of stimulus GO:0051606 84 0.011
neural retina development GO:0003407 41 0.011
regulation of t cell activation GO:0050863 170 0.011
regulation of neuron death GO:1901214 134 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
adult locomotory behavior GO:0008344 91 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
divalent metal ion transport GO:0070838 172 0.011
single organism cell adhesion GO:0098602 156 0.011
response to light stimulus GO:0009416 135 0.011
cardiac muscle contraction GO:0060048 32 0.011
peptide hormone secretion GO:0030072 109 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
cellularization GO:0007349 1 0.011
cerebellum development GO:0021549 77 0.011
male gamete generation GO:0048232 285 0.011
axon guidance GO:0007411 141 0.011
Worm
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
oxidation reduction process GO:0055114 342 0.011
organic anion transport GO:0015711 137 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
protein ubiquitination GO:0016567 171 0.010
tissue homeostasis GO:0001894 115 0.010
heart contraction GO:0060047 93 0.010
positive regulation of protein export from nucleus GO:0046827 4 0.010
calcium ion transmembrane transport GO:0070588 85 0.010
sulfur compound metabolic process GO:0006790 100 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
regulation of cellular component size GO:0032535 121 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
potassium ion transmembrane transport GO:0071805 43 0.010
asymmetric stem cell division GO:0098722 3 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
angiogenesis GO:0001525 201 0.010
striated muscle tissue development GO:0014706 293 0.010
protein localization to plasma membrane GO:0072659 57 0.010
membrane depolarization GO:0051899 64 0.010
regulation of protein processing GO:0070613 96 0.010
neuromuscular process GO:0050905 99 0.010
sperm motility GO:0030317 47 0.010
forebrain development GO:0030900 302 0.010
innate immune response GO:0045087 157 0.010

Unc13a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.026
disease of anatomical entity DOID:7 0 0.026
central nervous system disease DOID:331 0 0.013
disease of cellular proliferation DOID:14566 0 0.010