Mus musculus

53 known processes

Mbd4

methyl-CpG binding domain protein 4

(Aliases: Med1)

Mbd4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 107 0.355
dna metabolic process GO:0006259 303 0.257
cellular response to dna damage stimulus GO:0006974 207 0.176
cellular nitrogen compound catabolic process GO:0044270 280 0.127
epithelial tube morphogenesis GO:0060562 303 0.113
regulation of cell cycle process GO:0010564 160 0.112
aromatic compound catabolic process GO:0019439 286 0.109
dna recombination GO:0006310 92 0.104
chromatin organization GO:0006325 206 0.100
regulation of chromosome organization GO:0033044 83 0.098
purine nucleoside catabolic process GO:0006152 205 0.093
neural tube development GO:0021915 160 0.090
microtubule based process GO:0007017 236 0.090
chromatin modification GO:0016568 187 0.090
camera type eye development GO:0043010 266 0.088
meiotic cell cycle process GO:1903046 77 0.086
covalent chromatin modification GO:0016569 163 0.085
ribonucleoside catabolic process GO:0042454 206 0.083
embryonic epithelial tube formation GO:0001838 130 0.082
macromolecule catabolic process GO:0009057 281 0.082
heterocycle catabolic process GO:0046700 280 0.078
regulation of cellular amino acid metabolic process GO:0006521 5 0.075
cellular amine metabolic process GO:0044106 44 0.074
apoptotic signaling pathway GO:0097190 306 0.072
epithelial tube formation GO:0072175 130 0.072
mitotic cell cycle GO:0000278 195 0.070
organic cyclic compound catabolic process GO:1901361 295 0.070
tube formation GO:0035148 140 0.068
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.066
histone modification GO:0016570 159 0.065
cellular amino acid metabolic process GO:0006520 103 0.064
leukocyte differentiation GO:0002521 342 0.062
nucleoside catabolic process GO:0009164 206 0.060
cellular macromolecule catabolic process GO:0044265 206 0.060
intrinsic apoptotic signaling pathway GO:0097193 132 0.058
amine metabolic process GO:0009308 45 0.058
cellular ketone metabolic process GO:0042180 84 0.057
negative regulation of cell proliferation GO:0008285 296 0.056
regulation of cell cycle GO:0051726 281 0.056
cell division GO:0051301 120 0.053
regulation of cellular amine metabolic process GO:0033238 20 0.053
regulation of hydrolase activity GO:0051336 246 0.053
response to radiation GO:0009314 165 0.052
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.052
primary neural tube formation GO:0014020 95 0.050
purine ribonucleotide catabolic process GO:0009154 208 0.049
positive regulation of apoptotic process GO:0043065 217 0.048
protein ubiquitination GO:0016567 171 0.047
nucleoside phosphate catabolic process GO:1901292 222 0.047
dna biosynthetic process GO:0071897 22 0.046
protein modification by small protein conjugation GO:0032446 187 0.046
meiosis i GO:0007127 60 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.045
signal transduction involved in dna damage checkpoint GO:0072422 3 0.045
positive regulation of hydrolase activity GO:0051345 148 0.044
organophosphate catabolic process GO:0046434 232 0.044
nucleoside triphosphate catabolic process GO:0009143 205 0.043
positive regulation of protein modification process GO:0031401 299 0.043
membrane organization GO:0061024 245 0.042
organelle assembly GO:0070925 177 0.042
mitotic cell cycle process GO:1903047 159 0.041
purine containing compound catabolic process GO:0072523 213 0.041
regulation of organelle organization GO:0033043 289 0.041
protein processing GO:0016485 163 0.041
nucleoside triphosphate metabolic process GO:0009141 230 0.041
response to light stimulus GO:0009416 135 0.040
negative regulation of cellular component organization GO:0051129 194 0.039
sensory organ morphogenesis GO:0090596 242 0.039
glycosyl compound catabolic process GO:1901658 206 0.039
atp catabolic process GO:0006200 55 0.039
purine nucleoside triphosphate catabolic process GO:0009146 203 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
regulation of proteolysis GO:0030162 164 0.037
carbohydrate derivative catabolic process GO:1901136 231 0.037
dna replication GO:0006260 52 0.037
protein maturation GO:0051604 176 0.037
nucleotide metabolic process GO:0009117 332 0.037
negative regulation of cell cycle phase transition GO:1901988 48 0.036
telomere maintenance GO:0000723 19 0.036
double strand break repair GO:0006302 48 0.036
neural tube formation GO:0001841 108 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
nucleotide catabolic process GO:0009166 217 0.034
purine nucleotide catabolic process GO:0006195 211 0.034
morphogenesis of embryonic epithelium GO:0016331 159 0.033
lymphocyte differentiation GO:0030098 242 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
cellular response to organonitrogen compound GO:0071417 145 0.033
neural tube closure GO:0001843 90 0.033
spermatogenesis GO:0007283 284 0.033
regulation of cellular catabolic process GO:0031329 242 0.032
purine ribonucleoside catabolic process GO:0046130 205 0.032
mitochondrion organization GO:0007005 134 0.032
tube closure GO:0060606 91 0.032
purine nucleoside monophosphate catabolic process GO:0009128 58 0.032
male meiosis i GO:0007141 16 0.031
positive regulation of organelle organization GO:0010638 128 0.031
meiotic nuclear division GO:0007126 115 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
response to organonitrogen compound GO:0010243 246 0.031
appendage morphogenesis GO:0035107 149 0.031
purine ribonucleoside metabolic process GO:0046128 241 0.030
purine nucleoside monophosphate metabolic process GO:0009126 81 0.030
organelle fission GO:0048285 170 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
double strand break repair via homologous recombination GO:0000724 21 0.030
immune effector process GO:0002252 321 0.030
cellular response to abiotic stimulus GO:0071214 56 0.029
epithelial cell proliferation GO:0050673 174 0.029
b cell activation GO:0042113 161 0.029
mitotic nuclear division GO:0007067 48 0.029
regulation of mitotic cell cycle GO:0007346 126 0.029
smoothened signaling pathway GO:0007224 105 0.028
organonitrogen compound catabolic process GO:1901565 264 0.028
regulation of membrane potential GO:0042391 192 0.028
regulation of mitotic cell cycle phase transition GO:1901990 73 0.028
purine nucleoside triphosphate metabolic process GO:0009144 226 0.028
regulation of homeostatic process GO:0032844 182 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.028
meiotic cell cycle GO:0051321 122 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
negative regulation of organelle organization GO:0010639 90 0.027
gland development GO:0048732 330 0.027
nucleoside monophosphate metabolic process GO:0009123 85 0.027
translesion synthesis GO:0019985 1 0.026
myeloid cell differentiation GO:0030099 233 0.026
regulation of cell cycle phase transition GO:1901987 77 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
negative regulation of cell cycle GO:0045786 123 0.026
meiotic chromosome segregation GO:0045132 19 0.026
germ cell development GO:0007281 185 0.026
protein acylation GO:0043543 64 0.025
histone methylation GO:0016571 71 0.025
positive regulation of proteolysis GO:0045862 85 0.025
multicellular organism growth GO:0035264 161 0.025
positive regulation of cell death GO:0010942 224 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
cellular response to gamma radiation GO:0071480 4 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
cation transport GO:0006812 399 0.025
cation transmembrane transport GO:0098655 266 0.025
embryonic organ morphogenesis GO:0048562 276 0.025
nucleoside metabolic process GO:0009116 246 0.024
regulation of cell division GO:0051302 76 0.024
protein localization to organelle GO:0033365 185 0.024
intraciliary retrograde transport GO:0035721 3 0.024
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
peptidyl amino acid modification GO:0018193 336 0.023
microtubule cytoskeleton organization GO:0000226 157 0.023
purine containing compound metabolic process GO:0072521 311 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
ribonucleoside triphosphate catabolic process GO:0009203 199 0.023
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
signal transduction involved in mitotic cell cycle checkpoint GO:0072413 3 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
cell fate commitment GO:0045165 210 0.022
regulation of nuclear cell cycle dna replication GO:0033262 2 0.022
nuclear division GO:0000280 158 0.022
lymphocyte mediated immunity GO:0002449 139 0.022
muscle tissue development GO:0060537 308 0.022
homeostasis of number of cells GO:0048872 210 0.022
negative regulation of mitotic cell cycle GO:0045930 58 0.022
protein polymerization GO:0051258 57 0.022
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.021
cilium morphogenesis GO:0060271 102 0.021
methylation GO:0032259 134 0.021
anatomical structure homeostasis GO:0060249 145 0.021
negative regulation of nervous system development GO:0051961 156 0.020
regulation of cell activation GO:0050865 289 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
skeletal system development GO:0001501 356 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
regionalization GO:0003002 337 0.020
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.020
macromolecule methylation GO:0043414 120 0.020
cell type specific apoptotic process GO:0097285 268 0.020
female gonad development GO:0008585 71 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.019
regulation of protein kinase activity GO:0045859 232 0.019
innate immune response GO:0045087 157 0.019
sensory perception GO:0007600 245 0.019
respiratory system development GO:0060541 190 0.019
regulation of mitosis GO:0007088 29 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
chromosome segregation GO:0007059 48 0.019
atp metabolic process GO:0046034 75 0.019
modification dependent protein catabolic process GO:0019941 133 0.018
neural tube patterning GO:0021532 43 0.018
protein catabolic process GO:0030163 221 0.018
t cell activation GO:0042110 289 0.018
protein alkylation GO:0008213 81 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
transmembrane transport GO:0055085 412 0.018
ear development GO:0043583 200 0.018
negative regulation of cell division GO:0051782 24 0.018
mitotic sister chromatid segregation GO:0000070 14 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
negative regulation of dna replication GO:0008156 4 0.017
regulation of transferase activity GO:0051338 263 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
cellular homeostasis GO:0019725 240 0.017
cilium assembly GO:0042384 81 0.017
ras protein signal transduction GO:0007265 77 0.017
response to organic cyclic compound GO:0014070 198 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
limb development GO:0060173 166 0.017
neuronal action potential GO:0019228 54 0.017
glucose homeostasis GO:0042593 128 0.017
blood vessel morphogenesis GO:0048514 285 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
nucleoside monophosphate catabolic process GO:0009125 59 0.017
endomembrane system organization GO:0010256 147 0.016
male gamete generation GO:0048232 285 0.016
transmission of nerve impulse GO:0019226 76 0.016
positive regulation of cell cycle GO:0045787 92 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.016
negative regulation of molecular function GO:0044092 258 0.015
positive regulation of histone modification GO:0031058 28 0.015
response to growth factor GO:0070848 198 0.015
cellular protein catabolic process GO:0044257 155 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
embryonic limb morphogenesis GO:0030326 126 0.015
negative regulation of cell size GO:0045792 3 0.015
inner ear morphogenesis GO:0042472 101 0.015
signal transduction downstream of smoothened GO:0007227 4 0.015
rhythmic process GO:0048511 174 0.015
production of molecular mediator of immune response GO:0002440 103 0.015
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.015
gliogenesis GO:0042063 141 0.015
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.015
nuclear dna replication GO:0033260 3 0.015
intraciliary transport GO:0042073 9 0.015
ventricular compact myocardium morphogenesis GO:0003223 2 0.015
leukocyte mediated immunity GO:0002443 174 0.015
male meiosis GO:0007140 37 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
development of primary sexual characteristics GO:0045137 143 0.015
recombinational repair GO:0000725 21 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of circadian sleep wake cycle GO:0042749 3 0.014
mitotic cell cycle checkpoint GO:0007093 31 0.014
spermatid differentiation GO:0048515 115 0.014
b cell differentiation GO:0030183 78 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
microtubule organizing center organization GO:0031023 28 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.014
regulation of t cell activation GO:0050863 170 0.014
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.014
intestinal epithelial structure maintenance GO:0060729 4 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.014
sensory perception of sound GO:0007605 97 0.014
learning or memory GO:0007611 148 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
cellular response to peptide GO:1901653 92 0.014
peptidyl lysine modification GO:0018205 77 0.014
spermatid development GO:0007286 108 0.014
multicellular organismal signaling GO:0035637 91 0.014
ossification GO:0001503 216 0.014
regulation of protein maturation GO:1903317 96 0.014
embryonic appendage morphogenesis GO:0035113 126 0.013
positive regulation of apoptotic signaling pathway GO:2001235 95 0.013
chemotaxis GO:0006935 247 0.013
dna modification GO:0006304 50 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
regulation of chromatin modification GO:1903308 57 0.013
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.013
dna dependent dna replication GO:0006261 24 0.013
positive regulation of chromosome organization GO:2001252 33 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
blastocyst development GO:0001824 80 0.013
dna integrity checkpoint GO:0031570 28 0.013
immunoglobulin production GO:0002377 73 0.013
response to uv GO:0009411 44 0.013
cell cycle g1 s phase transition GO:0044843 57 0.013
cytoskeleton dependent intracellular transport GO:0030705 50 0.013
muscle cell differentiation GO:0042692 261 0.013
appendage development GO:0048736 166 0.013
neuron death GO:0070997 154 0.013
heterochromatin organization GO:0070828 4 0.013
maintenance of location GO:0051235 89 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
internal protein amino acid acetylation GO:0006475 42 0.012
regulation of histone modification GO:0031056 56 0.012
immunoglobulin mediated immune response GO:0016064 69 0.012
negative regulation of cell cycle process GO:0010948 69 0.012
protection from non homologous end joining at telomere GO:0031848 4 0.012
female meiosis chromosome segregation GO:0016321 1 0.012
compound eye development GO:0048749 1 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
regulation of chromatin organization GO:1902275 57 0.012
regulation of peptidase activity GO:0052547 96 0.012
wnt signaling pathway GO:0016055 188 0.012
somatic diversification of immune receptors GO:0002200 53 0.012
protein methylation GO:0006479 81 0.012
cellular chemical homeostasis GO:0055082 215 0.012
positive regulation of histone h3 k9 methylation GO:0051574 4 0.012
neuron apoptotic process GO:0051402 142 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.012
negative regulation of immune system process GO:0002683 209 0.012
rho protein signal transduction GO:0007266 32 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
mitotic chromosome condensation GO:0007076 1 0.012
proteasomal protein catabolic process GO:0010498 98 0.011
dna conformation change GO:0071103 37 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
branching morphogenesis of an epithelial tube GO:0048754 159 0.011
intracellular protein transport GO:0006886 204 0.011
dna catabolic process endonucleolytic GO:0000737 15 0.011
regulation of system process GO:0044057 200 0.011
regulation of smoothened signaling pathway GO:0008589 58 0.011
skeletal muscle organ development GO:0060538 163 0.011
divalent metal ion transport GO:0070838 172 0.011
female gamete generation GO:0007292 74 0.011
microtubule based movement GO:0007018 84 0.011
divalent inorganic cation transport GO:0072511 178 0.011
multi organism behavior GO:0051705 62 0.011
dna catabolic process GO:0006308 19 0.011
histone h3 k9 methylation GO:0051567 17 0.011
regulation of protein catabolic process GO:0042176 108 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
telomere maintenance in response to dna damage GO:0043247 4 0.011
negative regulation of smoothened signaling pathway GO:0045879 25 0.011
somatic diversification of immune receptors via somatic mutation GO:0002566 8 0.011
nitrogen compound transport GO:0071705 271 0.011
ear morphogenesis GO:0042471 118 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
regulation of transcription by chromatin organization GO:0034401 0 0.011
microtubule based transport GO:0010970 50 0.011
cognition GO:0050890 149 0.011
positive regulation of nervous system development GO:0051962 221 0.011
spinal cord development GO:0021510 81 0.011
ion transmembrane transport GO:0034220 361 0.010
carbohydrate homeostasis GO:0033500 128 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
actin filament based movement GO:0030048 23 0.010
regulation of protein processing GO:0070613 96 0.010
insulin secretion GO:0030073 89 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
regulation of neuron differentiation GO:0045664 281 0.010
response to insulin GO:0032868 100 0.010
calcium ion transport GO:0006816 159 0.010
tissue homeostasis GO:0001894 115 0.010
insulin receptor signaling pathway GO:0008286 49 0.010
cellular response to external stimulus GO:0071496 88 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.010
regulation of dna replication GO:0006275 17 0.010
positive regulation of endopeptidase activity GO:0010950 43 0.010
regulation of neuron death GO:1901214 134 0.010
lung development GO:0030324 164 0.010
negative regulation of cell development GO:0010721 169 0.010
lateral inhibition GO:0046331 1 0.010

Mbd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.041
cancer DOID:162 0 0.037
organ system cancer DOID:0050686 0 0.023
immune system disease DOID:2914 0 0.013
disease of anatomical entity DOID:7 0 0.013
hematopoietic system disease DOID:74 0 0.013
nervous system disease DOID:863 0 0.011
thoracic cancer DOID:5093 0 0.011
breast cancer DOID:1612 0 0.011