Mus musculus

0 known processes

Arhgef3

Rho guanine nucleotide exchange factor (GEF) 3

(Aliases: 9830169H03Rik,1200004I24Rik,C76747)

Arhgef3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside catabolic process GO:0009164 206 0.149
Fly
glycosyl compound metabolic process GO:1901657 246 0.140
Fly
ribonucleotide catabolic process GO:0009261 208 0.132
Fly
nucleotide catabolic process GO:0009166 217 0.130
Fly
nucleoside phosphate metabolic process GO:0006753 338 0.120
Fly
nucleoside triphosphate metabolic process GO:0009141 230 0.119
Fly
nucleoside metabolic process GO:0009116 246 0.117
Fly
purine nucleotide catabolic process GO:0006195 211 0.115
Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.109
Fly
ribonucleoside metabolic process GO:0009119 245 0.107
Fly
purine nucleoside metabolic process GO:0042278 241 0.101
Fly
nucleoside triphosphate catabolic process GO:0009143 205 0.095
Fly
organonitrogen compound catabolic process GO:1901565 264 0.095
Fly
regulation of cellular catabolic process GO:0031329 242 0.094
Fly
amine metabolic process GO:0009308 45 0.092
nucleobase containing small molecule metabolic process GO:0055086 352 0.090
Fly
ribonucleoside triphosphate catabolic process GO:0009203 199 0.086
Fly
purine nucleotide metabolic process GO:0006163 302 0.085
Fly
purine ribonucleotide catabolic process GO:0009154 208 0.085
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.078
Fly
gtp catabolic process GO:0006184 143 0.075
Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.073
cellular amine metabolic process GO:0044106 44 0.072
guanosine containing compound catabolic process GO:1901069 144 0.070
Fly
apoptotic signaling pathway GO:0097190 306 0.070
positive regulation of nucleotide catabolic process GO:0030813 88 0.070
Fly
positive regulation of programmed cell death GO:0043068 218 0.070
ras protein signal transduction GO:0007265 77 0.069
Fly
nucleotide metabolic process GO:0009117 332 0.069
Fly
positive regulation of cellular catabolic process GO:0031331 148 0.069
Fly
nucleoside phosphate catabolic process GO:1901292 222 0.069
Fly
purine ribonucleoside metabolic process GO:0046128 241 0.068
Fly
cellular ketone metabolic process GO:0042180 84 0.068
purine nucleoside triphosphate catabolic process GO:0009146 203 0.067
Fly
positive regulation of cell death GO:0010942 224 0.066
small gtpase mediated signal transduction GO:0007264 97 0.065
Fly
regulation of nucleotide metabolic process GO:0006140 169 0.065
Fly
heterocycle catabolic process GO:0046700 280 0.064
Fly
regulation of purine nucleotide catabolic process GO:0033121 122 0.061
Fly
actin cytoskeleton organization GO:0030036 220 0.061
glycosyl compound catabolic process GO:1901658 206 0.061
Fly
positive regulation of ras gtpase activity GO:0032320 65 0.061
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.059
Fly
ribose phosphate metabolic process GO:0019693 291 0.059
Fly
positive regulation of hydrolase activity GO:0051345 148 0.058
Fly
purine containing compound metabolic process GO:0072521 311 0.058
Fly
regulation of purine nucleotide metabolic process GO:1900542 169 0.058
Fly
ribonucleotide metabolic process GO:0009259 291 0.058
Fly
cellular amino acid metabolic process GO:0006520 103 0.056
positive regulation of apoptotic process GO:0043065 217 0.056
purine ribonucleotide metabolic process GO:0009150 290 0.054
Fly
purine nucleoside catabolic process GO:0006152 205 0.054
Fly
regulation of cellular amine metabolic process GO:0033238 20 0.050
g protein coupled receptor signaling pathway GO:0007186 243 0.050
regulation of ras gtpase activity GO:0032318 88 0.049
Fly
nitrogen compound transport GO:0071705 271 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.048
cellular nitrogen compound catabolic process GO:0044270 280 0.048
Fly
regulation of hydrolase activity GO:0051336 246 0.047
Fly
regulation of lymphocyte activation GO:0051249 240 0.046
purine ribonucleoside catabolic process GO:0046130 205 0.046
Fly
organic cyclic compound catabolic process GO:1901361 295 0.046
Fly
gtp metabolic process GO:0046039 144 0.045
Fly
positive regulation of gtp catabolic process GO:0033126 85 0.043
Fly
carbohydrate derivative catabolic process GO:1901136 231 0.043
Fly
cell adhesion GO:0007155 329 0.043
Mouse
negative regulation of molecular function GO:0044092 258 0.042
activation of immune response GO:0002253 138 0.042
guanosine containing compound metabolic process GO:1901068 144 0.041
Fly
organophosphate catabolic process GO:0046434 232 0.041
Fly
negative regulation of phosphate metabolic process GO:0045936 184 0.040
response to organonitrogen compound GO:0010243 246 0.040
ribonucleoside catabolic process GO:0042454 206 0.040
Fly
purine containing compound catabolic process GO:0072523 213 0.039
Fly
regulation of transferase activity GO:0051338 263 0.039
mapk cascade GO:0000165 281 0.038
negative regulation of protein metabolic process GO:0051248 282 0.037
cellular lipid metabolic process GO:0044255 323 0.037
protein modification by small protein conjugation or removal GO:0070647 207 0.036
regulation of mapk cascade GO:0043408 248 0.036
peptidyl amino acid modification GO:0018193 336 0.036
cytokine production GO:0001816 319 0.035
regulation of nucleotide catabolic process GO:0030811 122 0.035
Fly
cell type specific apoptotic process GO:0097285 268 0.035
aromatic compound catabolic process GO:0019439 286 0.034
Fly
positive regulation of gtpase activity GO:0043547 85 0.034
Fly
regulation of defense response GO:0031347 233 0.033
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.033
Fly
peptidyl tyrosine modification GO:0018212 145 0.033
positive regulation of protein modification process GO:0031401 299 0.033
response to lipopolysaccharide GO:0032496 128 0.033
myeloid cell differentiation GO:0030099 233 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.032
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.032
hematopoietic progenitor cell differentiation GO:0002244 143 0.031
regulation of cytokine production GO:0001817 266 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
endocytosis GO:0006897 168 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
Fly
immune effector process GO:0002252 321 0.030
negative regulation of phosphorus metabolic process GO:0010563 184 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
regulation of lymphocyte proliferation GO:0050670 117 0.029
regulation of kinase activity GO:0043549 249 0.029
innate immune response GO:0045087 157 0.029
negative regulation of protein phosphorylation GO:0001933 126 0.029
regulation of protein kinase activity GO:0045859 232 0.027
maintenance of location GO:0051235 89 0.027
regulation of secretion GO:0051046 274 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.026
peptide transport GO:0015833 133 0.026
cation transport GO:0006812 399 0.026
negative regulation of protein modification process GO:0031400 163 0.026
response to peptide GO:1901652 136 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
negative regulation of intracellular signal transduction GO:1902532 167 0.026
cell activation involved in immune response GO:0002263 126 0.025
regulation of nucleoside metabolic process GO:0009118 130 0.025
Fly
cellular response to dna damage stimulus GO:0006974 207 0.024
compound eye development GO:0048749 1 0.024
defense response to other organism GO:0098542 197 0.024
regulation of binding GO:0051098 111 0.024
phospholipid metabolic process GO:0006644 87 0.024
positive regulation of defense response GO:0031349 124 0.024
protein processing GO:0016485 163 0.024
actin filament organization GO:0007015 113 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
carbohydrate metabolic process GO:0005975 230 0.023
synaptic transmission GO:0007268 329 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
muscle system process GO:0003012 141 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
ion transmembrane transport GO:0034220 361 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.023
Fly
regulation of ion transport GO:0043269 215 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
regulation of cell activation GO:0050865 289 0.022
regulation of hormone levels GO:0010817 211 0.022
regulation of t cell activation GO:0050863 170 0.022
t cell activation GO:0042110 289 0.022
inflammatory response GO:0006954 244 0.022
intrinsic apoptotic signaling pathway GO:0097193 132 0.022
regulation of cell migration GO:0030334 219 0.022
immune response activating signal transduction GO:0002757 116 0.021
dephosphorylation GO:0016311 129 0.021
glucose homeostasis GO:0042593 128 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
carbohydrate homeostasis GO:0033500 128 0.020
chemotaxis GO:0006935 247 0.020
Fly
protein maturation GO:0051604 176 0.020
peptide secretion GO:0002790 114 0.020
regulation of secretion by cell GO:1903530 249 0.020
leukocyte differentiation GO:0002521 342 0.020
regulation of response to wounding GO:1903034 189 0.020
organelle fission GO:0048285 170 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
cellular response to cytokine stimulus GO:0071345 189 0.020
positive regulation of transferase activity GO:0051347 167 0.020
lipid biosynthetic process GO:0008610 179 0.019
regulation of protein localization GO:0032880 231 0.019
regulation of cellular response to stress GO:0080135 159 0.019
negative regulation of transferase activity GO:0051348 85 0.019
positive regulation of nucleoside metabolic process GO:0045979 91 0.019
Fly
lymphocyte differentiation GO:0030098 242 0.019
organophosphate biosynthetic process GO:0090407 122 0.019
leukocyte activation involved in immune response GO:0002366 126 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
spermatogenesis GO:0007283 284 0.019
dna metabolic process GO:0006259 303 0.018
respiratory system development GO:0060541 190 0.018
Fly
protein targeting GO:0006605 143 0.018
regulation of cell cycle process GO:0010564 160 0.018
leukocyte proliferation GO:0070661 172 0.018
gland development GO:0048732 330 0.018
regulation of ossification GO:0030278 112 0.018
insulin secretion GO:0030073 89 0.018
anion transport GO:0006820 177 0.018
positive regulation of cytokine production GO:0001819 174 0.018
protein ubiquitination GO:0016567 171 0.018
endomembrane system organization GO:0010256 147 0.018
positive regulation of apoptotic signaling pathway GO:2001235 95 0.018
regulation of cell motility GO:2000145 236 0.018
rap protein signal transduction GO:0032486 3 0.018
membrane organization GO:0061024 245 0.018
regulation of gtp catabolic process GO:0033124 113 0.018
Fly
response to molecule of bacterial origin GO:0002237 143 0.018
organelle localization GO:0051640 179 0.018
rhythmic process GO:0048511 174 0.017
protein localization to vacuole GO:0072665 4 0.017
muscle cell differentiation GO:0042692 261 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
peptide hormone secretion GO:0030072 109 0.017
response to peptide hormone GO:0043434 127 0.017
mitotic cell cycle process GO:1903047 159 0.017
midgut development GO:0007494 4 0.017
regulation of membrane potential GO:0042391 192 0.017
hormone secretion GO:0046879 128 0.017
extrinsic apoptotic signaling pathway GO:0097191 126 0.017
amide transport GO:0042886 138 0.017
regulation of rho protein signal transduction GO:0035023 71 0.017
Fly
microtubule based process GO:0007017 236 0.017
regulation of system process GO:0044057 200 0.017
response to organic cyclic compound GO:0014070 198 0.017
macromolecule catabolic process GO:0009057 281 0.016
nuclear division GO:0000280 158 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
multicellular organismal signaling GO:0035637 91 0.016
sequestering of metal ion GO:0051238 19 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
fat cell differentiation GO:0045444 160 0.016
lipid localization GO:0010876 126 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
regulation of innate immune response GO:0045088 91 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
Fly
glycerolipid metabolic process GO:0046486 122 0.016
stem cell differentiation GO:0048863 268 0.016
regulation of anatomical structure size GO:0090066 178 0.016
transmembrane transport GO:0055085 412 0.016
cellular chemical homeostasis GO:0055082 215 0.016
regulation of actin filament based process GO:0032970 99 0.016
cytoplasmic transport GO:0016482 234 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
immune response regulating signaling pathway GO:0002764 125 0.016
regulation of cell cycle GO:0051726 281 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
positive regulation of dna templated transcription elongation GO:0032786 2 0.015
protein kinase b signaling GO:0043491 74 0.015
skin development GO:0043588 220 0.015
atp metabolic process GO:0046034 75 0.015
positive regulation of interferon alpha production GO:0032727 4 0.015
positive regulation of kinase activity GO:0033674 155 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
metal ion homeostasis GO:0055065 189 0.015
oxidation reduction process GO:0055114 342 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
positive regulation of cell development GO:0010720 237 0.015
Mouse
response to nutrient levels GO:0031667 109 0.015
developmental maturation GO:0021700 193 0.015
regulation of inflammatory response GO:0050727 147 0.015
covalent chromatin modification GO:0016569 163 0.015
rho protein signal transduction GO:0007266 32 0.015
Fly
regulation of actin cytoskeleton organization GO:0032956 84 0.015
protein localization to organelle GO:0033365 185 0.015
macromolecule methylation GO:0043414 120 0.014
sequestering of calcium ion GO:0051208 18 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
axonogenesis GO:0007409 274 0.014
Fly
protein polymerization GO:0051258 57 0.014
locomotory behavior GO:0007626 195 0.014
muscle tissue development GO:0060537 308 0.014
regulation of protein transport GO:0051223 163 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
cellular response to lipid GO:0071396 145 0.014
male gamete generation GO:0048232 285 0.014
ossification GO:0001503 216 0.014
meiotic nuclear division GO:0007126 115 0.014
lymphocyte proliferation GO:0046651 164 0.014
monosaccharide transport GO:0015749 58 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
exocytosis GO:0006887 121 0.014
mitotic cell cycle GO:0000278 195 0.014
regulation of neuron differentiation GO:0045664 281 0.014
regulation of cell adhesion GO:0030155 154 0.014
Mouse
calcium ion homeostasis GO:0055074 127 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
homeostasis of number of cells GO:0048872 210 0.014
neuron apoptotic process GO:0051402 142 0.014
defense response to bacterium GO:0042742 119 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
t cell proliferation GO:0042098 120 0.013
cation transmembrane transport GO:0098655 266 0.013
regulation of homeostatic process GO:0032844 182 0.013
single organism cell adhesion GO:0098602 156 0.013
Mouse
regulation of transmembrane transport GO:0034762 128 0.013
regulation of body fluid levels GO:0050878 162 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
regulation of proteolysis GO:0030162 164 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
regulation of protein processing GO:0070613 96 0.013
regulation of organelle organization GO:0033043 289 0.013
negative regulation of cell cycle GO:0045786 123 0.013
regulation of peptidase activity GO:0052547 96 0.013
establishment of organelle localization GO:0051656 122 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
cellular ion homeostasis GO:0006873 165 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
intracellular protein transport GO:0006886 204 0.013
divalent metal ion transport GO:0070838 172 0.013
epidermis development GO:0008544 187 0.013
positive regulation of cell activation GO:0050867 158 0.013
action potential GO:0001508 78 0.013
circulatory system process GO:0003013 197 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
regulation of cell shape GO:0008360 39 0.013
transmission of nerve impulse GO:0019226 76 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
divalent inorganic cation transport GO:0072511 178 0.013
cellular response to organic cyclic compound GO:0071407 87 0.012
organic acid transport GO:0015849 101 0.012
positive regulation of nervous system development GO:0051962 221 0.012
wnt signaling pathway GO:0016055 188 0.012
stem cell development GO:0048864 219 0.012
response to insulin GO:0032868 100 0.012
respiratory tube development GO:0030323 167 0.012
cellular protein complex assembly GO:0043623 116 0.012
epithelial cell proliferation GO:0050673 174 0.012
striated muscle tissue development GO:0014706 293 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
Fly
regulation of neuron death GO:1901214 134 0.012
meiotic cell cycle GO:0051321 122 0.012
leukocyte mediated immunity GO:0002443 174 0.012
regulation of protein kinase b signaling GO:0051896 56 0.012
positive regulation of proteolysis GO:0045862 85 0.012
alcohol metabolic process GO:0006066 116 0.012
rab protein signal transduction GO:0032482 1 0.012
protein localization to membrane GO:0072657 108 0.012
negative regulation of protein maturation GO:1903318 79 0.012
protein targeting to vacuole GO:0006623 3 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
t cell differentiation GO:0030217 174 0.012
stress activated protein kinase signaling cascade GO:0031098 81 0.012
calcium ion transmembrane transport GO:0070588 85 0.012
response to inorganic substance GO:0010035 96 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
Mouse
regulation of intracellular protein transport GO:0033157 82 0.012
vesicle localization GO:0051648 86 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
positive regulation of secretion GO:0051047 130 0.012
blood vessel morphogenesis GO:0048514 285 0.012
cardiac muscle contraction GO:0060048 32 0.012
regulation of cellular component size GO:0032535 121 0.011
regulation of protein complex assembly GO:0043254 83 0.011
cellular homeostasis GO:0019725 240 0.011
myeloid leukocyte activation GO:0002274 83 0.011
positive regulation of leukocyte proliferation GO:0070665 73 0.011
actin filament polymerization GO:0030041 44 0.011
protein autophosphorylation GO:0046777 61 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
organelle assembly GO:0070925 177 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
regulation of vasculature development GO:1901342 88 0.011
regulation of feeding behavior GO:0060259 3 0.011
cation homeostasis GO:0055080 212 0.011
positive regulation of rho gtpase activity GO:0032321 41 0.011
Fly
blastocyst development GO:0001824 80 0.011
regulation of cell projection organization GO:0031344 206 0.011
positive regulation of innate immune response GO:0045089 80 0.011
neuron death GO:0070997 154 0.011
positive regulation of camp mediated signaling GO:0043950 3 0.011
cognition GO:0050890 149 0.011
regulation of voltage gated calcium channel activity GO:1901385 4 0.011
leukocyte migration GO:0050900 124 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
negative regulation of secretion GO:0051048 61 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
regulation of synaptic plasticity GO:0048167 87 0.011
b cell activation GO:0042113 161 0.011
actin filament based movement GO:0030048 23 0.011
regulation of engulfment of apoptotic cell GO:1901074 2 0.011
fertilization GO:0009566 127 0.011
regulation of protein maturation GO:1903317 96 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
cell maturation GO:0048469 127 0.010
hexose metabolic process GO:0019318 98 0.010
sensory perception GO:0007600 245 0.010
neuronal action potential GO:0019228 54 0.010
nuclear transport GO:0051169 139 0.010
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.010
membrane fusion GO:0061025 38 0.010
histone modification GO:0016570 159 0.010
positive regulation of organelle organization GO:0010638 128 0.010
response to light stimulus GO:0009416 135 0.010
interleukin 8 production GO:0032637 4 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
negative regulation of cell activation GO:0050866 111 0.010
methylation GO:0032259 134 0.010
chromatin modification GO:0016568 187 0.010
negative regulation of immune system process GO:0002683 209 0.010
purine nucleotide biosynthetic process GO:0006164 65 0.010
small molecule biosynthetic process GO:0044283 132 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
regulation of neuron projection development GO:0010975 169 0.010
negative regulation of neuron apoptotic process GO:0043524 92 0.010

Arhgef3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011