Mus musculus

0 known processes

Traf1

TNF receptor-associated factor 1

(Aliases: 4732496E14Rik)

Traf1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of defense response GO:0031347 233 0.892
Mouse
cytokine production GO:0001816 319 0.809
Mouse
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.712
positive regulation of t cell activation GO:0050870 101 0.657
Mouse
t cell differentiation GO:0030217 174 0.634
regulation of innate immune response GO:0045088 91 0.596
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.595
Mouse
t helper cell differentiation GO:0042093 28 0.583
adaptive immune response GO:0002250 155 0.580
Mouse
innate immune response GO:0045087 157 0.563
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.551
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.529
Mouse
defense response to other organism GO:0098542 197 0.525
Mouse
t cell proliferation GO:0042098 120 0.515
Mouse
regulation of cytokine production GO:0001817 266 0.483
Mouse
response to molecule of bacterial origin GO:0002237 143 0.476
Mouse
regulation of establishment of protein localization GO:0070201 181 0.454
Mouse
positive regulation of cytokine production GO:0001819 174 0.429
Mouse
leukocyte differentiation GO:0002521 342 0.425
Mouse
regulation of inflammatory response GO:0050727 147 0.404
alpha beta t cell activation GO:0046631 91 0.383
immune effector process GO:0002252 321 0.373
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.368
Mouse
t cell differentiation involved in immune response GO:0002292 30 0.360
regulation of protein transport GO:0051223 163 0.358
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.355
Mouse
cd4 positive alpha beta t cell activation GO:0035710 45 0.353
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.353
leukocyte mediated immunity GO:0002443 174 0.346
cytokine metabolic process GO:0042107 71 0.345
Mouse
immunoglobulin mediated immune response GO:0016064 69 0.313
interleukin 12 secretion GO:0072610 3 0.302
lymphocyte differentiation GO:0030098 242 0.301
positive regulation of inflammatory response GO:0050729 47 0.244
regulation of protein localization GO:0032880 231 0.241
Mouse
interleukin 10 secretion GO:0072608 4 0.238
regulation of t cell activation GO:0050863 170 0.237
Mouse
positive regulation of innate immune response GO:0045089 80 0.233
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.228
Mouse
negative regulation of immune system process GO:0002683 209 0.227
lymphocyte proliferation GO:0046651 164 0.223
Mouse
positive regulation of secretion GO:0051047 130 0.213
positive t cell selection GO:0043368 23 0.212
alpha beta t cell differentiation GO:0046632 69 0.210
production of molecular mediator of immune response GO:0002440 103 0.207
Mouse
protein secretion GO:0009306 111 0.205
Mouse
negative regulation of cytokine production GO:0001818 84 0.201
cytokine secretion GO:0050663 72 0.196
regulation of leukocyte mediated immunity GO:0002703 104 0.190
leukocyte activation involved in immune response GO:0002366 126 0.189
t cell activation GO:0042110 289 0.186
Mouse
leukocyte proliferation GO:0070661 172 0.184
Mouse
inflammatory response GO:0006954 244 0.174
i kappab kinase nf kappab signaling GO:0007249 85 0.171
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.164
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.161
Mouse
t helper 1 type immune response GO:0042088 25 0.161
Mouse
positive regulation of defense response GO:0031349 124 0.160
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.155
negative regulation of protein transport GO:0051224 46 0.153
positive regulation of immune effector process GO:0002699 107 0.150
t cell activation involved in immune response GO:0002286 43 0.148
negative regulation of protein metabolic process GO:0051248 282 0.147
defense response to gram positive bacterium GO:0050830 50 0.146
positive regulation of t cell proliferation GO:0042102 52 0.139
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.139
Human
immune response activating signal transduction GO:0002757 116 0.137
Mouse
regulation of membrane potential GO:0042391 192 0.134
regulation of hydrolase activity GO:0051336 246 0.130
regulation of lymphocyte proliferation GO:0050670 117 0.129
Mouse
positive regulation of leukocyte proliferation GO:0070665 73 0.124
Mouse
protein modification by small protein conjugation GO:0032446 187 0.123
Mouse
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.123
regulation of interleukin 10 secretion GO:2001179 4 0.121
dna recombination GO:0006310 92 0.121
response to lipopolysaccharide GO:0032496 128 0.120
Mouse
regulation of alpha beta t cell activation GO:0046634 53 0.120
regulation of interleukin 2 biosynthetic process GO:0045076 13 0.116
purine ribonucleoside metabolic process GO:0046128 241 0.116
positive regulation of cytokine biosynthetic process GO:0042108 40 0.112
Mouse
regulation of protein secretion GO:0050708 82 0.111
Mouse
regulation of cell activation GO:0050865 289 0.111
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.110
interleukin 2 production GO:0032623 33 0.109
myeloid cell differentiation GO:0030099 233 0.108
Mouse
regulation of t cell proliferation GO:0042129 92 0.107
Mouse
activation of immune response GO:0002253 138 0.107
Mouse
gliogenesis GO:0042063 141 0.107
regulation of secretion GO:0051046 274 0.107
Mouse
regulation of cytokine secretion GO:0050707 61 0.105
glycosyl compound metabolic process GO:1901657 246 0.105
cell activation involved in immune response GO:0002263 126 0.103
positive regulation of monocyte chemotaxis GO:0090026 2 0.103
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.102
negative regulation of protein secretion GO:0050709 20 0.102
cell adhesion GO:0007155 329 0.101
myeloid leukocyte activation GO:0002274 83 0.101
Mouse
ras protein signal transduction GO:0007265 77 0.101
regulation of lymphocyte activation GO:0051249 240 0.100
Mouse
positive regulation of programmed cell death GO:0043068 218 0.100
purine containing compound metabolic process GO:0072521 311 0.099
cation homeostasis GO:0055080 212 0.099
gland development GO:0048732 330 0.098
positive regulation of protein secretion GO:0050714 52 0.096
regulation of secretion by cell GO:1903530 249 0.096
Mouse
regulation of homeostatic process GO:0032844 182 0.096
negative regulation of defense response GO:0031348 77 0.095
somatic cell dna recombination GO:0016444 51 0.094
regulation of response to wounding GO:1903034 189 0.093
lymphocyte mediated immunity GO:0002449 139 0.093
cellular response to biotic stimulus GO:0071216 92 0.092
Mouse
t helper 1 cell differentiation GO:0045063 13 0.091
cdc42 protein signal transduction GO:0032488 0 0.090
regulation of proteolysis GO:0030162 164 0.090
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.088
nucleoside metabolic process GO:0009116 246 0.087
cellular homeostasis GO:0019725 240 0.087
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.086
immunoglobulin production GO:0002377 73 0.086
Mouse
regulation of interleukin 2 production GO:0032663 28 0.085
regulation of t cell differentiation GO:0045580 83 0.083
cytokine biosynthetic process GO:0042089 68 0.083
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.082
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.081
protein localization to organelle GO:0033365 185 0.080
negative regulation of secretion GO:0051048 61 0.080
nucleotide metabolic process GO:0009117 332 0.080
defense response to virus GO:0051607 68 0.079
Mouse
purine nucleotide metabolic process GO:0006163 302 0.078
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.078
negative regulation of secretion by cell GO:1903531 54 0.078
purine ribonucleotide metabolic process GO:0009150 290 0.078
dephosphorylation GO:0016311 129 0.077
regulation of leukocyte differentiation GO:1902105 159 0.077
carbohydrate derivative biosynthetic process GO:1901137 183 0.077
positive regulation of nucleotide metabolic process GO:0045981 114 0.077
glial cell differentiation GO:0010001 131 0.076
apoptotic signaling pathway GO:0097190 306 0.075
Human
positive regulation of leukocyte differentiation GO:1902107 86 0.075
positive regulation of mapk cascade GO:0043410 170 0.074
interleukin 2 biosynthetic process GO:0042094 15 0.072
cellular amino acid metabolic process GO:0006520 103 0.072
b cell mediated immunity GO:0019724 71 0.072
ribonucleoside triphosphate metabolic process GO:0009199 220 0.071
regulation of kinase activity GO:0043549 249 0.071
negative regulation of cellular protein metabolic process GO:0032269 247 0.071
homeostasis of number of cells GO:0048872 210 0.068
positive regulation of apoptotic process GO:0043065 217 0.066
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.066
ribose phosphate metabolic process GO:0019693 291 0.065
purine nucleoside metabolic process GO:0042278 241 0.065
ribonucleotide metabolic process GO:0009259 291 0.065
regulation of cysteine type endopeptidase activity GO:2000116 65 0.064
cell chemotaxis GO:0060326 81 0.064
response to organonitrogen compound GO:0010243 246 0.063
mature dendritic cell differentiation GO:0097029 3 0.063
t cell differentiation in thymus GO:0033077 77 0.061
positive regulation of protein phosphorylation GO:0001934 242 0.060
regulation of eosinophil migration GO:2000416 2 0.060
synaptic transmission GO:0007268 329 0.060
cell type specific apoptotic process GO:0097285 268 0.060
regulation of peptidase activity GO:0052547 96 0.059
lymphocyte activation involved in immune response GO:0002285 93 0.058
regulation of adaptive immune response GO:0002819 90 0.058
positive regulation of protein transport GO:0051222 93 0.058
neuron death GO:0070997 154 0.058
sequestering of calcium ion GO:0051208 18 0.058
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.057
protein homotrimerization GO:0070207 4 0.057
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.057
carbohydrate derivative catabolic process GO:1901136 231 0.057
positive regulation of cell activation GO:0050867 158 0.056
Mouse
carbohydrate metabolic process GO:0005975 230 0.056
regulation of endopeptidase activity GO:0052548 89 0.055
positive regulation of cell development GO:0010720 237 0.055
cellular metal ion homeostasis GO:0006875 151 0.055
divalent inorganic cation homeostasis GO:0072507 138 0.054
regulation of acute inflammatory response GO:0002673 27 0.054
thymocyte migration GO:0072679 2 0.054
interferon gamma production GO:0032609 67 0.054
nucleoside phosphate metabolic process GO:0006753 338 0.054
regulation of lymphocyte differentiation GO:0045619 107 0.054
small gtpase mediated signal transduction GO:0007264 97 0.054
positive regulation of interferon gamma production GO:0032729 39 0.054
protein import into nucleus GO:0006606 95 0.053
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.053
peptide transport GO:0015833 133 0.053
negative regulation of molecular function GO:0044092 258 0.053
Mouse
cellular response to tumor necrosis factor GO:0071356 21 0.053
Mouse
exocytosis GO:0006887 121 0.053
positive regulation of cell death GO:0010942 224 0.052
leukocyte migration GO:0050900 124 0.052
calcium ion transport GO:0006816 159 0.052
cation transport GO:0006812 399 0.052
activation of innate immune response GO:0002218 56 0.051
Mouse
muscle contraction GO:0006936 101 0.051
thymic t cell selection GO:0045061 22 0.051
cell growth GO:0016049 130 0.051
regulation of transferase activity GO:0051338 263 0.051
antigen receptor mediated signaling pathway GO:0050851 64 0.051
positive regulation of thymocyte migration GO:2000412 2 0.050
regulation of cytokine biosynthetic process GO:0042035 59 0.050
Mouse
protein import GO:0017038 101 0.050
negative regulation of apoptotic signaling pathway GO:2001234 104 0.050
t cell homeostasis GO:0043029 35 0.050
single organism nuclear import GO:1902593 95 0.050
epithelial cell proliferation GO:0050673 174 0.050
negative regulation of phosphorus metabolic process GO:0010563 184 0.050
positive regulation of t cell differentiation GO:0045582 52 0.050
multicellular organismal homeostasis GO:0048871 164 0.050
Mouse
regulation of ion transport GO:0043269 215 0.050
regulation of alpha beta t cell proliferation GO:0046640 18 0.050
establishment of protein localization to organelle GO:0072594 118 0.049
regulation of nucleotide metabolic process GO:0006140 169 0.049
negative regulation of t cell activation GO:0050868 65 0.049
cellular ion homeostasis GO:0006873 165 0.049
regulation of map kinase activity GO:0043405 120 0.049
leukocyte apoptotic process GO:0071887 71 0.049
regulation of cellular catabolic process GO:0031329 242 0.049
nucleotide catabolic process GO:0009166 217 0.049
positive regulation of gtpase activity GO:0043547 85 0.049
protein processing GO:0016485 163 0.049
negative regulation of interleukin 10 secretion GO:2001180 2 0.048
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.048
response to interferon gamma GO:0034341 34 0.047
mammary gland epithelium development GO:0061180 65 0.046
glycoprotein biosynthetic process GO:0009101 89 0.046
type 2 immune response GO:0042092 23 0.046
purine nucleoside triphosphate catabolic process GO:0009146 203 0.046
calcium ion homeostasis GO:0055074 127 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.046
t cell selection GO:0045058 34 0.045
nucleocytoplasmic transport GO:0006913 139 0.045
skeletal muscle organ development GO:0060538 163 0.045
neuron apoptotic process GO:0051402 142 0.045
positive regulation of secretion by cell GO:1903532 114 0.044
positive regulation of intracellular transport GO:0032388 70 0.044
purine nucleoside triphosphate metabolic process GO:0009144 226 0.044
t cell lineage commitment GO:0002360 13 0.044
metal ion homeostasis GO:0055065 189 0.044
purine nucleotide catabolic process GO:0006195 211 0.044
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.044
ossification GO:0001503 216 0.044
Mouse
response to peptide GO:1901652 136 0.044
negative regulation of inflammatory response GO:0050728 61 0.044
regulation of protein serine threonine kinase activity GO:0071900 157 0.043
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.043
regulation of cell adhesion GO:0030155 154 0.043
response to extracellular stimulus GO:0009991 127 0.043
positive regulation of cellular catabolic process GO:0031331 148 0.043
regulation of thymocyte migration GO:2000410 2 0.043
regulation of purine nucleotide metabolic process GO:1900542 169 0.043
acute inflammatory response GO:0002526 41 0.042
protein localization to nucleus GO:0034504 121 0.042
lymphocyte apoptotic process GO:0070227 54 0.042
muscle system process GO:0003012 141 0.042
defecation GO:0030421 1 0.042
ion transmembrane transport GO:0034220 361 0.041
cellular response to growth factor stimulus GO:0071363 197 0.041
positive regulation of eosinophil migration GO:2000418 2 0.041
regulation of peptide transport GO:0090087 91 0.040
regulation of organelle organization GO:0033043 289 0.040
regulation of multi organism process GO:0043900 111 0.040
Mouse
eosinophil migration GO:0072677 3 0.039
ribonucleoside metabolic process GO:0009119 245 0.039
negative regulation of protein processing GO:0010955 79 0.039
b cell activation GO:0042113 161 0.039
response to organic cyclic compound GO:0014070 198 0.039
negative regulation of growth GO:0045926 99 0.039
t helper 2 cell cytokine production GO:0035745 4 0.039
positive regulation of protein modification process GO:0031401 299 0.039
protein modification by small protein conjugation or removal GO:0070647 207 0.039
Mouse
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.039
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.038
negative regulation of leukocyte apoptotic process GO:2000107 31 0.038
nuclear transport GO:0051169 139 0.038
protein maturation GO:0051604 176 0.038
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.038
regulation of b cell activation GO:0050864 81 0.037
negative regulation of macrophage apoptotic process GO:2000110 3 0.037
negative regulation of cytokine secretion GO:0050710 15 0.037
positive regulation of ras gtpase activity GO:0032320 65 0.037
protein targeting GO:0006605 143 0.037
glycoprotein metabolic process GO:0009100 116 0.037
regulation of rho protein signal transduction GO:0035023 71 0.037
regulation of cellular ketone metabolic process GO:0010565 66 0.036
b cell activation involved in immune response GO:0002312 50 0.036
positive regulation of ion transport GO:0043270 65 0.036
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.035
regulation of muscle contraction GO:0006937 49 0.035
organic cyclic compound catabolic process GO:1901361 295 0.035
immune response regulating signaling pathway GO:0002764 125 0.035
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.035
regulation of mapk cascade GO:0043408 248 0.035
Mouse
interleukin 12 production GO:0032615 32 0.035
Mouse
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.034
regulation of intracellular protein transport GO:0033157 82 0.034
interferon beta biosynthetic process GO:0045350 4 0.034
cellular divalent inorganic cation homeostasis GO:0072503 127 0.034
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.034
regulation of cellular response to stress GO:0080135 159 0.034
Mouse
gtp metabolic process GO:0046039 144 0.034
sensory organ morphogenesis GO:0090596 242 0.034
cellular ketone metabolic process GO:0042180 84 0.034
cellular chemical homeostasis GO:0055082 215 0.034
regulation of lymphocyte mediated immunity GO:0002706 84 0.034
organonitrogen compound biosynthetic process GO:1901566 192 0.034
regulation of protein maturation GO:1903317 96 0.034
regulation of nucleotide catabolic process GO:0030811 122 0.033
nuclear import GO:0051170 95 0.033
regulation of interferon gamma production GO:0032649 57 0.033
regulation of protein targeting GO:1903533 61 0.033
transmembrane transport GO:0055085 412 0.033
positive regulation of b cell activation GO:0050871 49 0.033
alpha beta t cell proliferation GO:0046633 21 0.033
smooth muscle contraction GO:0006939 44 0.033
regulation of gtp catabolic process GO:0033124 113 0.033
regulation of muscle system process GO:0090257 80 0.033
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.033
rho protein signal transduction GO:0007266 32 0.033
muscle tissue development GO:0060537 308 0.033
nucleoside catabolic process GO:0009164 206 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
positive regulation of camp mediated signaling GO:0043950 3 0.032
negative regulation of protein modification process GO:0031400 163 0.032
sensory perception GO:0007600 245 0.032
regulation of cell killing GO:0031341 40 0.032
regulation of cell migration GO:0030334 219 0.031
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.031
positive regulation of alpha beta t cell activation GO:0046635 39 0.031
maintenance of location GO:0051235 89 0.031
regulation of neuron death GO:1901214 134 0.031
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.031
regulation of chemokine secretion GO:0090196 4 0.031
posttranscriptional regulation of gene expression GO:0010608 155 0.031
nitrogen compound transport GO:0071705 271 0.031
t cell mediated immunity GO:0002456 50 0.031
regulation of interleukin 4 biosynthetic process GO:0045402 3 0.030
t cell apoptotic process GO:0070231 39 0.030
cellular response to lipid GO:0071396 145 0.030
Mouse
cellular amine metabolic process GO:0044106 44 0.029
regulation of cytoplasmic transport GO:1903649 112 0.029
regulation of t cell apoptotic process GO:0070232 28 0.029
actin cytoskeleton organization GO:0030036 220 0.029
regulation of smooth muscle contraction GO:0006940 22 0.029
pattern recognition receptor signaling pathway GO:0002221 47 0.029
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.029
regulation of lipid metabolic process GO:0019216 118 0.029
positive regulation of epithelial cell proliferation GO:0050679 68 0.029
regulation of cellular component biogenesis GO:0044087 181 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
regulation of system process GO:0044057 200 0.028
transcription factor import into nucleus GO:0042991 26 0.028
tissue remodeling GO:0048771 102 0.028
Mouse
regulation of immunoglobulin production GO:0002637 42 0.028
Mouse
positive regulation of proteolysis GO:0045862 85 0.028
positive regulation of gtp catabolic process GO:0033126 85 0.027
regulation of leukocyte apoptotic process GO:2000106 56 0.027
positive regulation of lymphocyte differentiation GO:0045621 61 0.027
cytokine mediated signaling pathway GO:0019221 115 0.027
Mouse
regulation of protein processing GO:0070613 96 0.027
activation of mapk activity GO:0000187 59 0.027
negative regulation of protein maturation GO:1903318 79 0.027
learning or memory GO:0007611 148 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
negative regulation of cell activation GO:0050866 111 0.027
cellular response to external stimulus GO:0071496 88 0.027
engulfment of apoptotic cell GO:0043652 3 0.027
response to interleukin 4 GO:0070670 23 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
cellular response to molecule of bacterial origin GO:0071219 83 0.026
Mouse
regulation of anatomical structure size GO:0090066 178 0.026
positive regulation of transferase activity GO:0051347 167 0.026
osteoclast differentiation GO:0030316 62 0.026
Mouse
cellular lipid metabolic process GO:0044255 323 0.026
regulation of purine nucleotide catabolic process GO:0033121 122 0.026
dendritic cell differentiation GO:0097028 26 0.026
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.026
inorganic ion transmembrane transport GO:0098660 234 0.026
peptidyl amino acid modification GO:0018193 336 0.026
chemokine production GO:0032602 34 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
Human
cellular response to hormone stimulus GO:0032870 150 0.026
regulation of b cell mediated immunity GO:0002712 37 0.026
heterocycle catabolic process GO:0046700 280 0.025
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.025
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.025
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.025
regulation of ras gtpase activity GO:0032318 88 0.025
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.025
positive regulation of peptidase activity GO:0010952 49 0.025
cellular response to prostaglandin d stimulus GO:0071799 1 0.025
neutrophil migration GO:1990266 37 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
t cell migration GO:0072678 19 0.025
membrane depolarization GO:0051899 64 0.025
action potential GO:0001508 78 0.025
positive regulation of intracellular protein transport GO:0090316 42 0.025
regulation of protein kinase activity GO:0045859 232 0.025
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.025
purine containing compound catabolic process GO:0072523 213 0.025
positive regulation of rho gtpase activity GO:0032321 41 0.025
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.024
regulation of endocytosis GO:0030100 69 0.024
regulation of protein import into nucleus GO:0042306 52 0.024
positive regulation of cytokine secretion GO:0050715 41 0.024
microglia differentiation GO:0014004 2 0.024
regulation of lymphocyte apoptotic process GO:0070228 41 0.024
regulation of striated muscle cell differentiation GO:0051153 81 0.024
placenta development GO:0001890 140 0.024
regulation of immunoglobulin mediated immune response GO:0002889 37 0.024
protein catabolic process GO:0030163 221 0.024
Mouse
positive regulation of interleukin 2 biosynthetic process GO:0045086 8 0.024
cation transmembrane transport GO:0098655 266 0.024
granulocyte chemotaxis GO:0071621 39 0.024
mapk cascade GO:0000165 281 0.024
Mouse
protein oligomerization GO:0051259 67 0.024
regulation of type 2 immune response GO:0002828 18 0.023
rhythmic process GO:0048511 174 0.023
nucleoside phosphate biosynthetic process GO:1901293 79 0.023
membrane organization GO:0061024 245 0.023
positive regulation of cell killing GO:0031343 33 0.023
viral gene expression GO:0019080 3 0.023
intracellular protein transport GO:0006886 204 0.023
cell killing GO:0001906 67 0.023
defense response to protozoan GO:0042832 25 0.023
innate immune response activating signal transduction GO:0002758 50 0.023
Mouse
positive regulation of t cell costimulation GO:2000525 2 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
regulation of stress activated mapk cascade GO:0032872 69 0.022
Mouse
ensheathment of neurons GO:0007272 76 0.022
regulation of asymmetric cell division GO:0009786 4 0.022
regulation of metal ion transport GO:0010959 106 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
protein ubiquitination GO:0016567 171 0.022
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.022
protein kinase b signaling GO:0043491 74 0.022
protein homooligomerization GO:0051260 43 0.022
inflammatory response to antigenic stimulus GO:0002437 30 0.022
sequestering of metal ion GO:0051238 19 0.022
regulation of calcium ion transport GO:0051924 69 0.022
divalent metal ion transport GO:0070838 172 0.022
muscle cell differentiation GO:0042692 261 0.022
negative regulation of proteolysis GO:0045861 74 0.022
organic anion transport GO:0015711 137 0.022
interleukin 6 production GO:0032635 58 0.022
Mouse
negative regulation of phosphorylation GO:0042326 166 0.021
immune complex clearance by monocytes and macrophages GO:0002436 2 0.021
necrotic cell death GO:0070265 30 0.021
Mouse
response to transforming growth factor beta GO:0071559 88 0.021
cell recognition GO:0008037 83 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
germinal center formation GO:0002467 16 0.021
regulation of ossification GO:0030278 112 0.021
regulation of neuron differentiation GO:0045664 281 0.021
leukocyte mediated cytotoxicity GO:0001909 62 0.021
amine metabolic process GO:0009308 45 0.021
interleukin 8 production GO:0032637 4 0.021
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.021
multicellular organismal signaling GO:0035637 91 0.021
reactive oxygen species biosynthetic process GO:1903409 8 0.021
regulation of epithelial cell proliferation GO:0050678 141 0.021
aromatic compound catabolic process GO:0019439 286 0.021
helper t cell chemotaxis GO:0035704 1 0.021
forebrain development GO:0030900 302 0.020
cellular defense response GO:0006968 6 0.020
detection of stimulus GO:0051606 84 0.020
t cell receptor signaling pathway GO:0050852 46 0.020
natural killer cell activation GO:0030101 44 0.020
regulation of nucleocytoplasmic transport GO:0046822 73 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.020
Human
germ cell development GO:0007281 185 0.020
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.020
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
endocytosis GO:0006897 168 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
regulation of neuron apoptotic process GO:0043523 122 0.019
cellular response to peptide hormone stimulus GO:0071375 92 0.019
regulation of monocyte chemotaxis GO:0090025 3 0.019
renal system process GO:0003014 48 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
dna metabolic process GO:0006259 303 0.019
interleukin 1 production GO:0032612 31 0.019
regulation of t cell extravasation GO:2000407 3 0.019
positive regulation of cytoplasmic transport GO:1903651 40 0.019
microglia development GO:0014005 2 0.019
developmental cell growth GO:0048588 84 0.019
translation GO:0006412 93 0.019
regulation of intracellular transport GO:0032386 159 0.019
mitochondrion organization GO:0007005 134 0.019
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.019

Traf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.020
disease of anatomical entity DOID:7 0 0.020
musculoskeletal system disease DOID:17 0 0.020