Mus musculus

0 known processes

Prune

prune homolog (Drosophila)

(Aliases: Prune-M1,PRUNEM1,9230112O05Rik,HTCD37,C130058A12,DRES-17)

Prune biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small gtpase mediated signal transduction GO:0007264 97 0.046
heterocycle catabolic process GO:0046700 280 0.046
ras protein signal transduction GO:0007265 77 0.044
purine nucleoside metabolic process GO:0042278 241 0.043
organic cyclic compound catabolic process GO:1901361 295 0.042
protein catabolic process GO:0030163 221 0.039
apoptotic signaling pathway GO:0097190 306 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
macromolecule catabolic process GO:0009057 281 0.035
intracellular protein transport GO:0006886 204 0.035
glycosyl compound metabolic process GO:1901657 246 0.034
immune effector process GO:0002252 321 0.034
cell type specific apoptotic process GO:0097285 268 0.034
male gamete generation GO:0048232 285 0.034
membrane organization GO:0061024 245 0.033
regulation of organelle organization GO:0033043 289 0.032
aromatic compound catabolic process GO:0019439 286 0.032
dna metabolic process GO:0006259 303 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
regulation of cellular catabolic process GO:0031329 242 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.031
regulation of cell cycle GO:0051726 281 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
purine nucleoside catabolic process GO:0006152 205 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.029
cation transport GO:0006812 399 0.029
oxidation reduction process GO:0055114 342 0.029
purine containing compound metabolic process GO:0072521 311 0.029
organelle localization GO:0051640 179 0.029
regulation of secretion by cell GO:1903530 249 0.029
protein maturation GO:0051604 176 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
carbohydrate derivative catabolic process GO:1901136 231 0.029
cellular macromolecule catabolic process GO:0044265 206 0.028
chromatin modification GO:0016568 187 0.028
spermatogenesis GO:0007283 284 0.028
nucleotide metabolic process GO:0009117 332 0.028
organophosphate catabolic process GO:0046434 232 0.028
organonitrogen compound catabolic process GO:1901565 264 0.028
purine ribonucleoside metabolic process GO:0046128 241 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
cellular ketone metabolic process GO:0042180 84 0.027
regulation of intracellular transport GO:0032386 159 0.026
cellular amine metabolic process GO:0044106 44 0.026
gtp catabolic process GO:0006184 143 0.025
cellular response to hormone stimulus GO:0032870 150 0.025
cytokine production GO:0001816 319 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
anion transport GO:0006820 177 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
protein processing GO:0016485 163 0.025
mitotic cell cycle GO:0000278 195 0.025
actin cytoskeleton organization GO:0030036 220 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
meiotic cell cycle GO:0051321 122 0.025
cellular amino acid metabolic process GO:0006520 103 0.024
stem cell differentiation GO:0048863 268 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
cation transmembrane transport GO:0098655 266 0.024
regulation of secretion GO:0051046 274 0.024
regulation of protein localization GO:0032880 231 0.023
negative regulation of molecular function GO:0044092 258 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
nucleoside catabolic process GO:0009164 206 0.023
purine containing compound catabolic process GO:0072523 213 0.023
microtubule based process GO:0007017 236 0.023
nucleoside metabolic process GO:0009116 246 0.023
cellular protein catabolic process GO:0044257 155 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
muscle cell differentiation GO:0042692 261 0.022
germ cell development GO:0007281 185 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
chromatin organization GO:0006325 206 0.022
inflammatory response GO:0006954 244 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
peptidyl amino acid modification GO:0018193 336 0.021
protein localization to organelle GO:0033365 185 0.021
gtp metabolic process GO:0046039 144 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
cellular homeostasis GO:0019725 240 0.021
cellular lipid metabolic process GO:0044255 323 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
mitochondrion organization GO:0007005 134 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
positive regulation of cell development GO:0010720 237 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
protein ubiquitination GO:0016567 171 0.020
endomembrane system organization GO:0010256 147 0.020
t cell activation GO:0042110 289 0.020
regulation of membrane potential GO:0042391 192 0.020
endocytosis GO:0006897 168 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
mitotic cell cycle process GO:1903047 159 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
covalent chromatin modification GO:0016569 163 0.019
response to organonitrogen compound GO:0010243 246 0.019
rhythmic process GO:0048511 174 0.018
regulation of hydrolase activity GO:0051336 246 0.018
regulation of cell migration GO:0030334 219 0.018
cytoplasmic transport GO:0016482 234 0.018
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.018
cell adhesion GO:0007155 329 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
guanosine containing compound catabolic process GO:1901069 144 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
transmembrane transport GO:0055085 412 0.018
histone modification GO:0016570 159 0.018
maintenance of location GO:0051235 89 0.017
negative regulation of protein modification process GO:0031400 163 0.017
nucleotide catabolic process GO:0009166 217 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
positive regulation of cell death GO:0010942 224 0.017
cytokinetic process GO:0032506 2 0.017
negative regulation of cell cycle GO:0045786 123 0.017
organelle assembly GO:0070925 177 0.017
protein targeting GO:0006605 143 0.017
positive regulation of nervous system development GO:0051962 221 0.017
chemotaxis GO:0006935 247 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
regulation of cytokine production GO:0001817 266 0.017
regulation of cellular ketone metabolic process GO:0010565 66 0.017
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.017
nitrogen compound transport GO:0071705 271 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
nuclear transport GO:0051169 139 0.017
response to oxygen levels GO:0070482 62 0.016
regulation of cell activation GO:0050865 289 0.016
regulation of intracellular protein transport GO:0033157 82 0.016
dna repair GO:0006281 107 0.016
homeostasis of number of cells GO:0048872 210 0.016
dephosphorylation GO:0016311 129 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
rho protein signal transduction GO:0007266 32 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
ossification GO:0001503 216 0.016
myeloid cell differentiation GO:0030099 233 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
leukocyte differentiation GO:0002521 342 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
regulation of protein transport GO:0051223 163 0.016
lipid localization GO:0010876 126 0.016
negative regulation of cellular component organization GO:0051129 194 0.015
regulation of kinase activity GO:0043549 249 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
ion transmembrane transport GO:0034220 361 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
microtubule cytoskeleton organization GO:0000226 157 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
positive regulation of kinase activity GO:0033674 155 0.015
axonogenesis GO:0007409 274 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
regulation of proteolysis GO:0030162 164 0.015
regulation of transferase activity GO:0051338 263 0.015
response to insulin GO:0032868 100 0.015
establishment or maintenance of cell polarity GO:0007163 86 0.015
positive regulation of protein modification process GO:0031401 299 0.015
intracellular mrna localization GO:0008298 4 0.015
protein import into nucleus GO:0006606 95 0.015
exocytosis GO:0006887 121 0.015
locomotory behavior GO:0007626 195 0.015
amine metabolic process GO:0009308 45 0.015
regulation of protein kinase activity GO:0045859 232 0.014
response to peptide GO:1901652 136 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
regulation of neuron differentiation GO:0045664 281 0.014
translation GO:0006412 93 0.014
neuron death GO:0070997 154 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
cellular response to lipid GO:0071396 145 0.014
t cell differentiation GO:0030217 174 0.014
carbohydrate homeostasis GO:0033500 128 0.014
carbohydrate metabolic process GO:0005975 230 0.014
regulation of system process GO:0044057 200 0.014
wnt signaling pathway GO:0016055 188 0.014
positive regulation of cell cycle GO:0045787 92 0.014
methylation GO:0032259 134 0.014
regionalization GO:0003002 337 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
glucose homeostasis GO:0042593 128 0.014
macromolecule methylation GO:0043414 120 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
tube formation GO:0035148 140 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
regulation of cellular response to stress GO:0080135 159 0.014
regulation of lymphocyte activation GO:0051249 240 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
innate immune response GO:0045087 157 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
regulation of neuron death GO:1901214 134 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
regulation of t cell activation GO:0050863 170 0.013
regulation of cell cycle process GO:0010564 160 0.013
mapk cascade GO:0000165 281 0.013
organic anion transport GO:0015711 137 0.013
olfactory learning GO:0008355 2 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
regulation of multi organism process GO:0043900 111 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
single organism cell adhesion GO:0098602 156 0.013
neuron apoptotic process GO:0051402 142 0.013
defense response to other organism GO:0098542 197 0.013
spermatid development GO:0007286 108 0.013
response to inorganic substance GO:0010035 96 0.013
response to oxidative stress GO:0006979 123 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
response to growth factor GO:0070848 198 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
oocyte axis specification GO:0007309 2 0.013
renal system development GO:0072001 225 0.013
phagocytosis GO:0006909 66 0.013
organelle fission GO:0048285 170 0.013
protein oligomerization GO:0051259 67 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of anatomical structure size GO:0090066 178 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
tissue homeostasis GO:0001894 115 0.012
skeletal system morphogenesis GO:0048705 203 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.012
anion transmembrane transport GO:0098656 71 0.012
striated muscle tissue development GO:0014706 293 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
regulation of cell projection organization GO:0031344 206 0.012
stem cell development GO:0048864 219 0.012
rna processing GO:0006396 105 0.012
syncytium formation by plasma membrane fusion GO:0000768 42 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
localization within membrane GO:0051668 4 0.012
positive regulation of cell motility GO:2000147 116 0.012
protein import GO:0017038 101 0.012
regulation of hormone levels GO:0010817 211 0.012
cellular chemical homeostasis GO:0055082 215 0.012
circadian rhythm GO:0007623 114 0.012
neural tube formation GO:0001841 108 0.012
positive regulation of organelle organization GO:0010638 128 0.012
cellularization GO:0007349 1 0.012
cation homeostasis GO:0055080 212 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
regulation of voltage gated calcium channel activity GO:1901385 4 0.012
organic acid transport GO:0015849 101 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
cell division GO:0051301 120 0.011
regulation of cell motility GO:2000145 236 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
metal ion homeostasis GO:0055065 189 0.011
positive regulation of transferase activity GO:0051347 167 0.011
wound healing GO:0042060 157 0.011
skeletal system development GO:0001501 356 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
regulation of protein processing GO:0070613 96 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
neuron migration GO:0001764 122 0.011
cell cell recognition GO:0009988 44 0.011
multi multicellular organism process GO:0044706 109 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
response to extracellular stimulus GO:0009991 127 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
actin filament organization GO:0007015 113 0.011
skeletal muscle organ development GO:0060538 163 0.011
cellular response to peptide GO:1901653 92 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
meiosis i GO:0007127 60 0.011
development of primary sexual characteristics GO:0045137 143 0.011
nuclear division GO:0000280 158 0.011
jnk cascade GO:0007254 72 0.011
divalent metal ion transport GO:0070838 172 0.011
divalent inorganic cation transport GO:0072511 178 0.011
meiotic nuclear division GO:0007126 115 0.011
respiratory system development GO:0060541 190 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
regulation of protein maturation GO:1903317 96 0.011
plasma membrane organization GO:0007009 90 0.011
spermatid differentiation GO:0048515 115 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
lymphocyte differentiation GO:0030098 242 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
connective tissue development GO:0061448 179 0.010
muscle tissue development GO:0060537 308 0.010
leukocyte proliferation GO:0070661 172 0.010
cell activation involved in immune response GO:0002263 126 0.010
response to organic cyclic compound GO:0014070 198 0.010
camera type eye development GO:0043010 266 0.010
extracellular matrix organization GO:0030198 147 0.010
oocyte construction GO:0007308 2 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
protein localization to membrane GO:0072657 108 0.010
single organism nuclear import GO:1902593 95 0.010
regulation of homeostatic process GO:0032844 182 0.010
mitochondrion distribution GO:0048311 4 0.010
developmental maturation GO:0021700 193 0.010
positive regulation of immune effector process GO:0002699 107 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
regulation of feeding behavior GO:0060259 3 0.010
mesodermal cell migration GO:0008078 4 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
negative regulation of nervous system development GO:0051961 156 0.010
telencephalon development GO:0021537 186 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010

Prune disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
disease of metabolism DOID:0014667 0 0.015
cancer DOID:162 0 0.013
musculoskeletal system disease DOID:17 0 0.013
organ system cancer DOID:0050686 0 0.013
immune system disease DOID:2914 0 0.012
inherited metabolic disorder DOID:655 0 0.012