Mus musculus

0 known processes

Eif2b5

eukaryotic translation initiation factor 2B, subunit 5 epsilon

(Aliases: C81315)

Eif2b5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine nucleotide metabolic process GO:0006163 302 0.224
Human Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.202
Human Rat
translation GO:0006412 93 0.159
Human Rat
nucleotide metabolic process GO:0009117 332 0.100
Human Rat
heterocycle catabolic process GO:0046700 280 0.097
Human Rat
purine containing compound catabolic process GO:0072523 213 0.082
Human Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.078
Human Rat
protein modification by small protein conjugation or removal GO:0070647 207 0.078
purine nucleoside triphosphate catabolic process GO:0009146 203 0.076
Human Rat
purine ribonucleoside metabolic process GO:0046128 241 0.070
Human Rat
purine nucleoside triphosphate metabolic process GO:0009144 226 0.065
Human Rat
nucleoside triphosphate metabolic process GO:0009141 230 0.065
Human Rat
negative regulation of protein metabolic process GO:0051248 282 0.064
Rat
regulation of translation GO:0006417 71 0.060
Rat
ribose phosphate metabolic process GO:0019693 291 0.060
Human Rat
positive regulation of protein modification process GO:0031401 299 0.060
rna processing GO:0006396 105 0.058
organonitrogen compound catabolic process GO:1901565 264 0.056
Human Rat
cellular amino acid metabolic process GO:0006520 103 0.056
regulation of cellular amine metabolic process GO:0033238 20 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.055
macromolecule catabolic process GO:0009057 281 0.053
nucleoside metabolic process GO:0009116 246 0.052
Human Rat
purine containing compound metabolic process GO:0072521 311 0.051
Human Rat
cellular nitrogen compound catabolic process GO:0044270 280 0.050
Human Rat
ribonucleotide catabolic process GO:0009261 208 0.049
Human Rat
amine metabolic process GO:0009308 45 0.048
ribonucleoside catabolic process GO:0042454 206 0.048
Human Rat
carbohydrate derivative catabolic process GO:1901136 231 0.045
Human Rat
organic cyclic compound catabolic process GO:1901361 295 0.045
Human Rat
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
cellular amine metabolic process GO:0044106 44 0.044
ribonucleoside triphosphate catabolic process GO:0009203 199 0.044
Human Rat
nucleoside catabolic process GO:0009164 206 0.042
Human Rat
glycosyl compound catabolic process GO:1901658 206 0.042
Human Rat
organophosphate catabolic process GO:0046434 232 0.042
Human Rat
glycosyl compound metabolic process GO:1901657 246 0.042
Human Rat
small gtpase mediated signal transduction GO:0007264 97 0.041
nucleoside triphosphate catabolic process GO:0009143 205 0.041
Human Rat
regulation of purine nucleotide catabolic process GO:0033121 122 0.040
Human Rat
purine ribonucleotide catabolic process GO:0009154 208 0.040
Human Rat
purine ribonucleotide metabolic process GO:0009150 290 0.040
Human Rat
cellular ketone metabolic process GO:0042180 84 0.040
purine ribonucleoside catabolic process GO:0046130 205 0.039
Human Rat
purine nucleotide catabolic process GO:0006195 211 0.038
Human Rat
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
Human Rat
cellular macromolecule catabolic process GO:0044265 206 0.037
protein modification by small protein conjugation GO:0032446 187 0.036
nucleotide catabolic process GO:0009166 217 0.035
Human Rat
embryonic organ morphogenesis GO:0048562 276 0.035
lymphocyte differentiation GO:0030098 242 0.034
ribonucleoside metabolic process GO:0009119 245 0.034
Human Rat
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
protein ubiquitination GO:0016567 171 0.033
aromatic compound catabolic process GO:0019439 286 0.032
Human Rat
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
Rat
protein catabolic process GO:0030163 221 0.032
gonad development GO:0008406 141 0.031
Human
nucleoside monophosphate metabolic process GO:0009123 85 0.031
rna splicing GO:0008380 54 0.031
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
nuclear division GO:0000280 158 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
development of primary sexual characteristics GO:0045137 143 0.029
Human
regulation of cell cycle process GO:0010564 160 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
Human Rat
protein modification by small protein removal GO:0070646 21 0.028
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
Human Rat
regulation of hydrolase activity GO:0051336 246 0.027
Human Rat
regulation of cell cycle GO:0051726 281 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
germ cell development GO:0007281 185 0.025
ras protein signal transduction GO:0007265 77 0.025
mitotic cell cycle GO:0000278 195 0.025
regulation of cellular component biogenesis GO:0044087 181 0.024
ribonucleoside monophosphate catabolic process GO:0009158 57 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
Human Rat
negative regulation of intracellular signal transduction GO:1902532 167 0.023
protein maturation GO:0051604 176 0.022
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.021
methylation GO:0032259 134 0.021
peptidyl amino acid modification GO:0018193 336 0.021
regulation of organelle organization GO:0033043 289 0.021
t cell activation GO:0042110 289 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
organelle assembly GO:0070925 177 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.019
nucleoside monophosphate catabolic process GO:0009125 59 0.019
regulation of protein complex assembly GO:0043254 83 0.019
divalent metal ion transport GO:0070838 172 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.019
t cell differentiation GO:0030217 174 0.019
regulation of establishment of protein localization GO:0070201 181 0.018
organelle fission GO:0048285 170 0.018
regulation of mapk cascade GO:0043408 248 0.018
macromolecule methylation GO:0043414 120 0.017
gland development GO:0048732 330 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
Rat
purine nucleoside catabolic process GO:0006152 205 0.017
Human Rat
endocytosis GO:0006897 168 0.017
negative regulation of protein modification process GO:0031400 163 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
Human Rat
regulation of transferase activity GO:0051338 263 0.017
mitotic cell cycle process GO:1903047 159 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
Human Rat
negative regulation of protein phosphorylation GO:0001933 126 0.016
leukocyte differentiation GO:0002521 342 0.016
positive regulation of transferase activity GO:0051347 167 0.016
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.016
positive regulation of gtp catabolic process GO:0033126 85 0.016
Human Rat
protein processing GO:0016485 163 0.016
mapk cascade GO:0000165 281 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
regulation of membrane potential GO:0042391 192 0.015
Human
nucleoside phosphate catabolic process GO:1901292 222 0.015
Human Rat
regulation of mrna metabolic process GO:1903311 43 0.015
regulation of protein catabolic process GO:0042176 108 0.015
regulation of cell activation GO:0050865 289 0.015
regulation of chromosome organization GO:0033044 83 0.015
regulation of t cell activation GO:0050863 170 0.015
t cell differentiation in thymus GO:0033077 77 0.014
ribonucleoprotein complex subunit organization GO:0071826 28 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
regulation of proteolysis GO:0030162 164 0.014
axonogenesis GO:0007409 274 0.014
trna wobble uridine modification GO:0002098 2 0.014
regulation of kinase activity GO:0043549 249 0.014
chromatin organization GO:0006325 206 0.014
spermatogenesis GO:0007283 284 0.014
protein localization to organelle GO:0033365 185 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
Human Rat
rna splicing via transesterification reactions GO:0000375 43 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
cell recognition GO:0008037 83 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
Human Rat
response to light stimulus GO:0009416 135 0.013
skeletal system development GO:0001501 356 0.013
regulation of feeding behavior GO:0060259 3 0.013
spermatid differentiation GO:0048515 115 0.013
negative regulation of molecular function GO:0044092 258 0.013
response to radiation GO:0009314 165 0.013
regulation of protein ubiquitination GO:0031396 52 0.013
transmission of nerve impulse GO:0019226 76 0.013
Human
ribonucleotide metabolic process GO:0009259 291 0.013
Human Rat
protein polymerization GO:0051258 57 0.012
cytokine production GO:0001816 319 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
mrna metabolic process GO:0016071 84 0.012
response to organonitrogen compound GO:0010243 246 0.012
Rat
regulation of protein maturation GO:1903317 96 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
microtubule based process GO:0007017 236 0.012
transmembrane transport GO:0055085 412 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
atp metabolic process GO:0046034 75 0.012
ensheathment of neurons GO:0007272 76 0.012
Human
negative regulation of cellular catabolic process GO:0031330 47 0.012
positive regulation of gtpase activity GO:0043547 85 0.011
Human Rat
negative regulation of protein maturation GO:1903318 79 0.011
female gamete generation GO:0007292 74 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
Human Rat
regulation of lymphocyte differentiation GO:0045619 107 0.011
regulation of protein kinase activity GO:0045859 232 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
meiotic nuclear division GO:0007126 115 0.011
apoptotic signaling pathway GO:0097190 306 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
Human Rat
dephosphorylation GO:0016311 129 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
Human Rat
positive regulation of programmed cell death GO:0043068 218 0.010
dna metabolic process GO:0006259 303 0.010
ncrna processing GO:0034470 26 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
multicellular organism growth GO:0035264 161 0.010
leukocyte apoptotic process GO:0071887 71 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
rho protein signal transduction GO:0007266 32 0.010
development of primary male sexual characteristics GO:0046546 88 0.010
genitalia development GO:0048806 37 0.010

Eif2b5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
eye disease DOID:5614 0 0.017
retinal disease DOID:5679 0 0.017
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
organ system cancer DOID:0050686 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
cancer DOID:162 0 0.010