|
|
cellular response to leptin stimulus
|
GO:0044320 |
6 |
0.936
|
|
|
|
regulation of ovulation
|
GO:0060278 |
3 |
0.931
|
|
|
|
follicle stimulating hormone secretion
|
GO:0046884 |
1 |
0.920
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.897
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.887
|
|
|
|
progesterone secretion
|
GO:0042701 |
1 |
0.879
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.853
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.824
|
|
|
|
palate development
|
GO:0060021 |
76 |
0.794
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.787
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.785
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.783
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.769
|
|
|
|
tissue regeneration
|
GO:0042246 |
22 |
0.768
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.764
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.751
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.748
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.746
|
Zebrafish |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.734
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.723
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.712
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.706
|
|
|
|
negative regulation of insulin secretion
|
GO:0046676 |
14 |
0.687
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.684
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.676
|
Mouse |
|
|
renal system development
|
GO:0072001 |
225 |
0.667
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.663
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.655
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.649
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.641
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.639
|
Human Mouse |
|
|
response to cholesterol
|
GO:0070723 |
4 |
0.637
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.628
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.627
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.621
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.617
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.601
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
18 |
0.590
|
Human |
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.578
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.576
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.574
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.573
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.572
|
|
|
|
cellular response to cholesterol
|
GO:0071397 |
2 |
0.568
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.563
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.555
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.550
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.548
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.547
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.539
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.538
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.535
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.527
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.527
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.515
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.514
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.512
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.509
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.508
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.507
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.506
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.505
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.504
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.503
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.502
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.502
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.498
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.493
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.492
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.492
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.488
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.486
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.483
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.480
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.475
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.470
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.464
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.462
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.461
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.454
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.453
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.442
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.441
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.439
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.439
|
|
|
|
cellular response to follicle stimulating hormone stimulus
|
GO:0071372 |
1 |
0.436
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.436
|
|
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.430
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.427
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.421
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.418
|
|
|
|
cellular response to sterol
|
GO:0036315 |
2 |
0.416
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.411
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.409
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.405
|
|
|
|
response to leptin
|
GO:0044321 |
7 |
0.397
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.395
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
44 |
0.393
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.391
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.387
|
Mouse |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.386
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.385
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.382
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.376
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.375
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.374
|
Human |
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.370
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.368
|
|
|
|
negative regulation of peptide hormone secretion
|
GO:0090278 |
16 |
0.365
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.363
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.362
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.361
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.361
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.360
|
Zebrafish |
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.347
|
Mouse |
|
|
hormone secretion
|
GO:0046879 |
128 |
0.345
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.337
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.331
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.331
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
10 |
0.328
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.320
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.319
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.317
|
|
|
|
eyelid development in camera type eye
|
GO:0061029 |
9 |
0.317
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.317
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.313
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.312
|
|
|
|
heart valve morphogenesis
|
GO:0003179 |
21 |
0.308
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.307
|
Zebrafish |
|
|
histone modification
|
GO:0016570 |
159 |
0.306
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.306
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.302
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.301
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.300
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.299
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.298
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.297
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.295
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.294
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.290
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.289
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.283
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.281
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.277
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.277
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.275
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.274
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.273
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.269
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.268
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.267
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.267
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.264
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.260
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.259
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.257
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.252
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.251
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.249
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.246
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.244
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.244
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.243
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.240
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.240
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.239
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.236
|
|
|
|
endocrine hormone secretion
|
GO:0060986 |
15 |
0.235
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.234
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.233
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.232
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.232
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.230
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.230
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.227
|
|
|
|
ovulation
|
GO:0030728 |
15 |
0.227
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.227
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
10 |
0.225
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.225
|
|
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.224
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.222
|
|
|
|
negative regulation of hormone secretion
|
GO:0046888 |
20 |
0.221
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.220
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.219
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.217
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.214
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.210
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.210
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.207
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.203
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.198
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.198
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.198
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.196
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.194
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.194
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.194
|
|
|
|
regulation of dna binding
|
GO:0051101 |
39 |
0.193
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.193
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.191
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.191
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.191
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.191
|
|
|
|
myoblast differentiation involved in skeletal muscle regeneration
|
GO:0014835 |
3 |
0.190
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.189
|
|
|
|
cellular response to alcohol
|
GO:0097306 |
23 |
0.188
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.188
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.186
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.186
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.185
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.183
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.182
|
Zebrafish |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.181
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.180
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.180
|
|
|
|
negative regulation of peptide secretion
|
GO:0002792 |
16 |
0.179
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.178
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.178
|
Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.177
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.176
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.176
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.173
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.173
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.172
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.172
|
|
|
|
skin morphogenesis
|
GO:0043589 |
38 |
0.171
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.171
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.169
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.169
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
13 |
0.167
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.166
|
Mouse |
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.164
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.164
|
|
|
|
cellular response to gonadotropin stimulus
|
GO:0071371 |
4 |
0.161
|
|
|
|
regulation of morphogenesis of a branching structure
|
GO:0060688 |
53 |
0.159
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.159
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.159
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.159
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.156
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.156
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
10 |
0.154
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.153
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.152
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.151
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
13 |
0.150
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.149
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.146
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.144
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.143
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.141
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.141
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.140
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.140
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.138
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.137
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.137
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.136
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
33 |
0.135
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.134
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.134
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.133
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.131
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.130
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.130
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.128
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.127
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.127
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.127
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.126
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.124
|
|
|
|
negative regulation of binding
|
GO:0051100 |
39 |
0.124
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.122
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.122
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.122
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.121
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.121
|
|
|
|
positive regulation of reproductive process
|
GO:2000243 |
19 |
0.120
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.120
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.119
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.118
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.118
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.118
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.117
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.115
|
|
|
|
cell aggregation
|
GO:0098743 |
18 |
0.115
|
|
|
|
protein deacetylation
|
GO:0006476 |
32 |
0.114
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.114
|
Zebrafish |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.113
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.113
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.113
|
|
|
|
cartilage condensation
|
GO:0001502 |
18 |
0.113
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.113
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.113
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.112
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.111
|
|
|
|
skeletal muscle tissue regeneration
|
GO:0043403 |
20 |
0.110
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.110
|
Zebrafish |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.109
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.109
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.109
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.109
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.109
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.107
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.106
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.106
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.105
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.104
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.104
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.104
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.104
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.103
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.102
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.101
|
|
|
|
lung morphogenesis
|
GO:0060425 |
50 |
0.101
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.100
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.099
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.099
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.099
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.099
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
27 |
0.099
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.098
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.097
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.096
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.096
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.096
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.096
|
|
|
|
head morphogenesis
|
GO:0060323 |
34 |
0.096
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
28 |
0.095
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.095
|
|
|
|
mesonephric duct morphogenesis
|
GO:0072180 |
4 |
0.095
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.095
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.095
|
|
|
|
heart valve development
|
GO:0003170 |
23 |
0.093
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.092
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.092
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.092
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.092
|
|
|
|
muscle hypertrophy
|
GO:0014896 |
24 |
0.090
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
22 |
0.090
|
|
|
|
cerebellum morphogenesis
|
GO:0021587 |
42 |
0.090
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.089
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
33 |
0.089
|
|
|
|
axis elongation
|
GO:0003401 |
30 |
0.089
|
|
|
|
negative regulation of dna binding
|
GO:0043392 |
20 |
0.089
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.089
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.088
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.088
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.088
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.088
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.088
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.087
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.087
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.087
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.086
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.086
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.086
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.086
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.084
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.084
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.084
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.084
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.083
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.083
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.083
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.083
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.083
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.082
|
|
|
|
chondrocyte development
|
GO:0002063 |
24 |
0.082
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.082
|
|
|
|
muscle atrophy
|
GO:0014889 |
3 |
0.081
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.081
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.081
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
33 |
0.080
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.079
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.079
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.079
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.079
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.078
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.078
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.078
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.078
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.078
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.077
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.077
|
|
|
|
striated muscle atrophy
|
GO:0014891 |
2 |
0.077
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.076
|
|
|
|
axis elongation involved in somitogenesis
|
GO:0090245 |
4 |
0.076
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.076
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.076
|
|
|
|
face development
|
GO:0060324 |
38 |
0.076
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.075
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.075
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.075
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.074
|
|
|
|
branch elongation of an epithelium
|
GO:0060602 |
19 |
0.074
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.074
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.074
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.073
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.073
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.072
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.072
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.072
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.072
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.072
|
|
|
|
response to heat
|
GO:0009408 |
27 |
0.071
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.071
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.070
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.070
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.070
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.070
|
|
|
|
positive regulation of interleukin 17 production
|
GO:0032740 |
3 |
0.070
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.070
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.069
|
|
|
|
negative regulation of cartilage development
|
GO:0061037 |
17 |
0.069
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.069
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.069
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.069
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
33 |
0.068
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.068
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.067
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
29 |
0.066
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.066
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
23 |
0.066
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
17 |
0.066
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.066
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.065
|
|
|
|
metanephric tubule development
|
GO:0072170 |
18 |
0.065
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.064
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.064
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.064
|
|
|
|
pancreas development
|
GO:0031016 |
57 |
0.064
|
|
|
|
canonical wnt signaling pathway involved in regulation of cell proliferation
|
GO:0044340 |
3 |
0.063
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.063
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.063
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
54 |
0.063
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.063
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.063
|
|
|
|
response to follicle stimulating hormone
|
GO:0032354 |
1 |
0.063
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.062
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.062
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.062
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.061
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.061
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.061
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.061
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.061
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.060
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.060
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.060
|
|
|
|
neural crest cell development
|
GO:0014032 |
48 |
0.059
|
|
|
|
blood vessel remodeling
|
GO:0001974 |
33 |
0.059
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.059
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.059
|
|
|
|
endocrine process
|
GO:0050886 |
39 |
0.059
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.058
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.058
|
|
|
|
negative regulation of mesenchymal cell proliferation
|
GO:0072201 |
3 |
0.057
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.057
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.057
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.057
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.057
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.057
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
37 |
0.057
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.056
|
|
|
|
regulation of endocrine process
|
GO:0044060 |
13 |
0.056
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.056
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.056
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.056
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.056
|
|
|
|
positive regulation of transforming growth factor beta2 production
|
GO:0032915 |
2 |
0.056
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.056
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.056
|
|
|
|
positive regulation of striated muscle tissue development
|
GO:0045844 |
31 |
0.055
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
17 |
0.055
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.055
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.055
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.054
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.054
|
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.054
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.054
|
|
|
|
endochondral bone growth
|
GO:0003416 |
19 |
0.054
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.054
|
|
|
|
endoderm formation
|
GO:0001706 |
20 |
0.054
|
|
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
58 |
0.053
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.053
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.053
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.053
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.053
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.053
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.052
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.052
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.052
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.052
|
|
|
|
planar cell polarity pathway involved in outflow tract morphogenesis
|
GO:0061347 |
2 |
0.051
|
|
|
|
response to estrogen
|
GO:0043627 |
24 |
0.051
|
|
|
|
regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045898 |
2 |
0.051
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.051
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.051
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.050
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.050
|
|
