Mus musculus

331 known processes

Ptpn2

protein tyrosine phosphatase, non-receptor type 2

(Aliases: AI325124,TC-PTP,Ptpt)

Ptpn2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
myeloid cell differentiation GO:0030099 233 0.561
dna metabolic process GO:0006259 303 0.504
cellular response to cytokine stimulus GO:0071345 189 0.476
gland development GO:0048732 330 0.454
apoptotic signaling pathway GO:0097190 306 0.384
protein processing GO:0016485 163 0.367
regulation of cytokine production GO:0001817 266 0.364
cellular amino acid metabolic process GO:0006520 103 0.347
extrinsic apoptotic signaling pathway GO:0097191 126 0.335
regulation of cellular ketone metabolic process GO:0010565 66 0.330
amine metabolic process GO:0009308 45 0.315
regulation of defense response GO:0031347 233 0.305
negative regulation of molecular function GO:0044092 258 0.300
Mouse
positive regulation of programmed cell death GO:0043068 218 0.296
regulation of endopeptidase activity GO:0052548 89 0.292
positive regulation of cytokine production GO:0001819 174 0.283
positive regulation of endopeptidase activity GO:0010950 43 0.283
cytokine mediated signaling pathway GO:0019221 115 0.280
regulation of kinase activity GO:0043549 249 0.271
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.262
erythrocyte differentiation GO:0030218 88 0.253
cytokine production GO:0001816 319 0.250
negative regulation of immune system process GO:0002683 209 0.240
regulation of apoptotic signaling pathway GO:2001233 197 0.239
leukocyte differentiation GO:0002521 342 0.238
response to organonitrogen compound GO:0010243 246 0.236
response to organic cyclic compound GO:0014070 198 0.230
cellular response to hormone stimulus GO:0032870 150 0.223
regulation of cysteine type endopeptidase activity GO:2000116 65 0.216
regulation of cellular amine metabolic process GO:0033238 20 0.206
zymogen activation GO:0031638 41 0.206
spermatogenesis GO:0007283 284 0.206
male gamete generation GO:0048232 285 0.201
negative regulation of cell proliferation GO:0008285 296 0.198
Human
positive regulation of apoptotic signaling pathway GO:2001235 95 0.191
regulation of lymphocyte differentiation GO:0045619 107 0.189
regulation of peptidase activity GO:0052547 96 0.186
cellular amine metabolic process GO:0044106 44 0.182
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.180
protein maturation GO:0051604 176 0.172
immune effector process GO:0002252 321 0.172
stem cell differentiation GO:0048863 268 0.169
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.167
positive regulation of cell death GO:0010942 224 0.164
rhythmic process GO:0048511 174 0.161
regulation of cellular amino acid metabolic process GO:0006521 5 0.161
regulation of hydrolase activity GO:0051336 246 0.161
response to molecule of bacterial origin GO:0002237 143 0.159
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.156
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.155
liposaccharide metabolic process GO:1903509 27 0.150
negative regulation of lymphocyte activation GO:0051250 91 0.149
peptidyl tyrosine modification GO:0018212 145 0.145
response to peptide GO:1901652 136 0.142
positive regulation of protein modification process GO:0031401 299 0.139
wnt signaling pathway GO:0016055 188 0.138
negative regulation of growth GO:0045926 99 0.135
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.134
positive regulation of leukocyte differentiation GO:1902107 86 0.134
stem cell development GO:0048864 219 0.134
osteoclast differentiation GO:0030316 62 0.129
response to lipopolysaccharide GO:0032496 128 0.124
activation of cysteine type endopeptidase activity GO:0097202 27 0.124
regulation of protein kinase activity GO:0045859 232 0.124
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.121
cellular response to lipopolysaccharide GO:0071222 77 0.119
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.119
defense response to other organism GO:0098542 197 0.119
cellular response to organonitrogen compound GO:0071417 145 0.118
cellular response to lipid GO:0071396 145 0.117
positive regulation of apoptotic process GO:0043065 217 0.116
positive regulation of protein phosphorylation GO:0001934 242 0.116
myeloid leukocyte differentiation GO:0002573 119 0.116
placenta development GO:0001890 140 0.115
regulation of leukocyte differentiation GO:1902105 159 0.115
regulation of transferase activity GO:0051338 263 0.113
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.111
negative regulation of protein metabolic process GO:0051248 282 0.111
spermatid differentiation GO:0048515 115 0.110
negative regulation of cellular amine metabolic process GO:0033239 1 0.108
response to peptide hormone GO:0043434 127 0.107
positive regulation of cell development GO:0010720 237 0.104
carbohydrate metabolic process GO:0005975 230 0.104
cellular response to organic cyclic compound GO:0071407 87 0.103
regulation of neuron differentiation GO:0045664 281 0.103
t cell differentiation GO:0030217 174 0.100
protein ubiquitination GO:0016567 171 0.099
stem cell maintenance GO:0019827 130 0.097
digestive system development GO:0055123 200 0.097
regulation of secretion GO:0051046 274 0.097
spermatid development GO:0007286 108 0.096
digestive tract development GO:0048565 190 0.096
regulation of myeloid cell differentiation GO:0045637 96 0.096
defense response to virus GO:0051607 68 0.095
striated muscle tissue development GO:0014706 293 0.093
peptidyl amino acid modification GO:0018193 336 0.093
lactation GO:0007595 25 0.091
cellular response to biotic stimulus GO:0071216 92 0.091
regulation of secretion by cell GO:1903530 249 0.091
regulation of body fluid levels GO:0050878 162 0.089
development of primary sexual characteristics GO:0045137 143 0.086
positive regulation of cellular amine metabolic process GO:0033240 5 0.085
positive regulation of peptidase activity GO:0010952 49 0.085
positive regulation of secretion GO:0051047 130 0.085
b cell activation GO:0042113 161 0.084
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.082
cellular response to dna damage stimulus GO:0006974 207 0.082
fat cell differentiation GO:0045444 160 0.081
mapk cascade GO:0000165 281 0.079
axonogenesis GO:0007409 274 0.079
morphogenesis of a branching epithelium GO:0061138 193 0.077
t helper cell differentiation GO:0042093 28 0.077
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.077
regulation of jak stat cascade GO:0046425 34 0.074
circadian regulation of gene expression GO:0032922 48 0.074
homeostasis of number of cells GO:0048872 210 0.074
regulation of leukocyte mediated immunity GO:0002703 104 0.073
macromolecule catabolic process GO:0009057 281 0.073
muscle tissue development GO:0060537 308 0.072
leukocyte mediated immunity GO:0002443 174 0.072
regulation of adaptive immune response GO:0002819 90 0.071
regulation of t cell activation GO:0050863 170 0.069
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.069
leukocyte homeostasis GO:0001776 79 0.068
regulation of inflammatory response GO:0050727 147 0.068
lymphocyte differentiation GO:0030098 242 0.067
regulation of lymphocyte activation GO:0051249 240 0.067
circadian rhythm GO:0007623 114 0.067
jak stat cascade GO:0007259 42 0.067
cell activation involved in immune response GO:0002263 126 0.067
inflammatory response GO:0006954 244 0.066
learning or memory GO:0007611 148 0.066
regulation of myeloid leukocyte differentiation GO:0002761 58 0.065
negative regulation of intracellular signal transduction GO:1902532 167 0.065
skeletal system development GO:0001501 356 0.065
respiratory system development GO:0060541 190 0.064
blood vessel morphogenesis GO:0048514 285 0.063
compound eye development GO:0048749 1 0.062
adaptive immune response GO:0002250 155 0.061
i kappab kinase nf kappab signaling GO:0007249 85 0.061
cellular response to molecule of bacterial origin GO:0071219 83 0.061
cellular ketone metabolic process GO:0042180 84 0.060
regulation of cellular catabolic process GO:0031329 242 0.060
positive regulation of kinase activity GO:0033674 155 0.060
t helper 1 type immune response GO:0042088 25 0.060
digestive tract morphogenesis GO:0048546 147 0.060
mesenchyme development GO:0060485 152 0.060
t cell differentiation in thymus GO:0033077 77 0.059
t cell activation GO:0042110 289 0.059
glucose homeostasis GO:0042593 128 0.059
positive regulation of t cell activation GO:0050870 101 0.059
negative regulation of cellular protein metabolic process GO:0032269 247 0.059
multicellular organism growth GO:0035264 161 0.058
activation of janus kinase activity GO:0042976 2 0.058
cell type specific apoptotic process GO:0097285 268 0.058
positive regulation of protein kinase activity GO:0045860 144 0.057
protein modification by small protein conjugation or removal GO:0070647 207 0.056
negative regulation of nervous system development GO:0051961 156 0.056
muscle cell differentiation GO:0042692 261 0.056
organic cyclic compound catabolic process GO:1901361 295 0.055
leukocyte activation involved in immune response GO:0002366 126 0.055
protein localization to organelle GO:0033365 185 0.055
lymphocyte homeostasis GO:0002260 64 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.054
intracellular protein transport GO:0006886 204 0.054
carbohydrate derivative biosynthetic process GO:1901137 183 0.054
germ cell development GO:0007281 185 0.054
establishment of protein localization to organelle GO:0072594 118 0.053
rna processing GO:0006396 105 0.053
embryonic placenta development GO:0001892 98 0.053
regulation of response to wounding GO:1903034 189 0.053
posttranscriptional regulation of gene expression GO:0010608 155 0.053
cognition GO:0050890 149 0.053
regulation of organelle organization GO:0033043 289 0.053
body fluid secretion GO:0007589 53 0.052
regulation of hormone levels GO:0010817 211 0.051
regulation of cell growth GO:0001558 91 0.051
respiratory tube development GO:0030323 167 0.051
cytoplasmic transport GO:0016482 234 0.051
camera type eye development GO:0043010 266 0.050
ubiquitin dependent protein catabolic process GO:0006511 129 0.050
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.050
positive regulation of nervous system development GO:0051962 221 0.050
regulation of t cell differentiation GO:0045580 83 0.050
regulation of fat cell differentiation GO:0045598 81 0.049
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.049
myeloid cell homeostasis GO:0002262 114 0.049
cellular lipid metabolic process GO:0044255 323 0.048
protein modification by small protein conjugation GO:0032446 187 0.048
lipid localization GO:0010876 126 0.048
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.046
nuclear transport GO:0051169 139 0.046
response to growth factor GO:0070848 198 0.046
Mouse
positive regulation of myeloid cell differentiation GO:0045639 43 0.045
response to interleukin 15 GO:0070672 3 0.045
positive regulation of lymphocyte proliferation GO:0050671 70 0.045
ossification GO:0001503 216 0.045
regulation of wnt signaling pathway GO:0030111 123 0.045
maintenance of location GO:0051235 89 0.045
negative regulation of cell growth GO:0030308 44 0.045
urogenital system development GO:0001655 261 0.044
protein secretion GO:0009306 111 0.044
regulation of hormone secretion GO:0046883 88 0.043
peptidyl tyrosine phosphorylation GO:0018108 143 0.043
hormone secretion GO:0046879 128 0.043
cellular response to oxidative stress GO:0034599 76 0.043
negative regulation of binding GO:0051100 39 0.043
regulation of proteolysis GO:0030162 164 0.043
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.042
positive regulation of transferase activity GO:0051347 167 0.042
positive regulation of proteolysis GO:0045862 85 0.042
cellular protein catabolic process GO:0044257 155 0.042
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.042
regulation of leukocyte proliferation GO:0070663 121 0.041
response to steroid hormone GO:0048545 56 0.041
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.041
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.040
t cell differentiation involved in immune response GO:0002292 30 0.040
negative regulation of t cell activation GO:0050868 65 0.040
modification dependent protein catabolic process GO:0019941 133 0.040
lymphocyte activation involved in immune response GO:0002285 93 0.040
locomotory behavior GO:0007626 195 0.040
generation of precursor metabolites and energy GO:0006091 103 0.039
multi multicellular organism process GO:0044706 109 0.039
secretory granule organization GO:0033363 20 0.039
negative regulation of lymphocyte differentiation GO:0045620 32 0.038
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 10 0.038
Human
response to oxidative stress GO:0006979 123 0.038
negative regulation of cellular component organization GO:0051129 194 0.038
microtubule based process GO:0007017 236 0.037
cellular response to peptide GO:1901653 92 0.037
negative regulation of cell activation GO:0050866 111 0.037
chemotaxis GO:0006935 247 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.037
male sex differentiation GO:0046661 109 0.036
regulation of leukocyte apoptotic process GO:2000106 56 0.036
developmental maturation GO:0021700 193 0.036
chromatin organization GO:0006325 206 0.036
nuclear division GO:0000280 158 0.036
mesenchymal cell differentiation GO:0048762 107 0.035
cell growth GO:0016049 130 0.035
canonical wnt signaling pathway GO:0060070 130 0.035
regulation of cell projection organization GO:0031344 206 0.035
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.035
response to alcohol GO:0097305 48 0.034
cellular homeostasis GO:0019725 240 0.034
lung development GO:0030324 164 0.034
regulation of cellular response to stress GO:0080135 159 0.034
neuron apoptotic process GO:0051402 142 0.034
regulation of production of molecular mediator of immune response GO:0002700 65 0.034
regeneration GO:0031099 38 0.034
regulation of t cell proliferation GO:0042129 92 0.034
regulation of embryonic development GO:0045995 71 0.033
morphogenesis of a branching structure GO:0001763 203 0.033
negative regulation of apoptotic signaling pathway GO:2001234 104 0.033
regulation of cell activation GO:0050865 289 0.033
cellular response to external stimulus GO:0071496 88 0.033
cellular response to growth factor stimulus GO:0071363 197 0.033
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.033
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.033
cellular chemical homeostasis GO:0055082 215 0.032
alpha beta t cell differentiation GO:0046632 69 0.032
regulation of anatomical structure size GO:0090066 178 0.032
alpha beta t cell activation GO:0046631 91 0.032
negative regulation of t cell differentiation GO:0045581 23 0.031
tyrosine phosphorylation of stat3 protein GO:0042503 12 0.031
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
negative regulation of cell development GO:0010721 169 0.031
morphogenesis of embryonic epithelium GO:0016331 159 0.031
single organism nuclear import GO:1902593 95 0.031
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.031
cellular response to peptide hormone stimulus GO:0071375 92 0.031
nuclear import GO:0051170 95 0.031
cell adhesion GO:0007155 329 0.031
membrane lipid metabolic process GO:0006643 53 0.031
modification dependent macromolecule catabolic process GO:0043632 133 0.030
immunoglobulin production GO:0002377 73 0.030
positive regulation of lymphocyte activation GO:0051251 140 0.030
negative regulation of protein modification process GO:0031400 163 0.030
regionalization GO:0003002 337 0.030
negative regulation of secretion GO:0051048 61 0.030
diencephalon development GO:0021536 63 0.030
glycolipid metabolic process GO:0006664 25 0.030
pole plasm assembly GO:0007315 2 0.030
cell maturation GO:0048469 127 0.030
t cell apoptotic process GO:0070231 39 0.029
response to nutrient levels GO:0031667 109 0.029
single organism cell adhesion GO:0098602 156 0.029
myeloid leukocyte activation GO:0002274 83 0.029
regulation of protein localization GO:0032880 231 0.029
telencephalon development GO:0021537 186 0.028
endocytosis GO:0006897 168 0.028
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.028
positive regulation of t cell proliferation GO:0042102 52 0.028
organelle localization GO:0051640 179 0.028
retina development in camera type eye GO:0060041 119 0.028
glycoprotein biosynthetic process GO:0009101 89 0.027
anion transport GO:0006820 177 0.027
t cell proliferation GO:0042098 120 0.027
gastrulation GO:0007369 116 0.027
response to radiation GO:0009314 165 0.027
oocyte axis specification GO:0007309 2 0.027
epithelial tube morphogenesis GO:0060562 303 0.027
regulation of mapk cascade GO:0043408 248 0.026
regulation of cell migration GO:0030334 219 0.026
hindbrain development GO:0030902 128 0.026
positive regulation of mapk cascade GO:0043410 170 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
forebrain development GO:0030900 302 0.026
peptidyl lysine modification GO:0018205 77 0.026
endocrine system development GO:0035270 98 0.026
cellular response to steroid hormone stimulus GO:0071383 33 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
t cell activation involved in immune response GO:0002286 43 0.026
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.026
response to light stimulus GO:0009416 135 0.026
cytokine metabolic process GO:0042107 71 0.026
somatic diversification of immune receptors GO:0002200 53 0.026
regulation of protein maturation GO:1903317 96 0.026
regulation of homeostatic process GO:0032844 182 0.026
hematopoietic progenitor cell differentiation GO:0002244 143 0.026
heterocycle catabolic process GO:0046700 280 0.025
positive regulation of defense response GO:0031349 124 0.025
lipid storage GO:0019915 36 0.025
regulation of lymphocyte proliferation GO:0050670 117 0.025
protein import GO:0017038 101 0.025
developmental growth involved in morphogenesis GO:0060560 138 0.025
regulation of epithelial cell proliferation GO:0050678 141 0.025
cd4 positive alpha beta t cell activation GO:0035710 45 0.025
rna interference GO:0016246 2 0.025
neuron death GO:0070997 154 0.025
cytokine secretion GO:0050663 72 0.025
gpi anchor biosynthetic process GO:0006506 6 0.024
response to insulin GO:0032868 100 0.024
mrna processing GO:0006397 63 0.024
b cell differentiation GO:0030183 78 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
response to inorganic substance GO:0010035 96 0.024
cellular response to acid chemical GO:0071229 68 0.024
regulation of membrane potential GO:0042391 192 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
mammary gland epithelium development GO:0061180 65 0.024
metal ion homeostasis GO:0055065 189 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
positive regulation of fat cell differentiation GO:0045600 32 0.023
regulation of carbohydrate metabolic process GO:0006109 75 0.023
ribosomal small subunit biogenesis GO:0042274 4 0.023
leukocyte proliferation GO:0070661 172 0.023
carbohydrate homeostasis GO:0033500 128 0.023
cell fate commitment GO:0045165 210 0.023
dna recombination GO:0006310 92 0.023
cellular response to inorganic substance GO:0071241 37 0.023
chromatin modification GO:0016568 187 0.023
developmental cell growth GO:0048588 84 0.023
protein autophosphorylation GO:0046777 61 0.023
positive regulation of epithelial cell proliferation GO:0050679 68 0.023
cellular carbohydrate metabolic process GO:0044262 119 0.023
positive regulation of growth GO:0045927 104 0.022
cell division GO:0051301 120 0.022
gliogenesis GO:0042063 141 0.022
regulation of neuron projection development GO:0010975 169 0.022
cation homeostasis GO:0055080 212 0.022
dendrite development GO:0016358 115 0.022
response to oxygen levels GO:0070482 62 0.022
regulation of ion transport GO:0043269 215 0.022
aromatic compound catabolic process GO:0019439 286 0.022
skeletal system morphogenesis GO:0048705 203 0.022
neuron projection guidance GO:0097485 141 0.022
lymphocyte proliferation GO:0046651 164 0.022
alpha beta t cell activation involved in immune response GO:0002287 31 0.022
transmission of nerve impulse GO:0019226 76 0.022
organic acid transport GO:0015849 101 0.022
positive regulation of secretion by cell GO:1903532 114 0.022
regulation of binding GO:0051098 111 0.022
negative regulation of leukocyte differentiation GO:1902106 51 0.022
branching morphogenesis of an epithelial tube GO:0048754 159 0.022
small gtpase mediated signal transduction GO:0007264 97 0.021
female gamete generation GO:0007292 74 0.021
meiotic cell cycle process GO:1903046 77 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
positive regulation of hormone secretion GO:0046887 38 0.021
purine containing compound metabolic process GO:0072521 311 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.021
peptide hormone secretion GO:0030072 109 0.021
notch signaling pathway GO:0007219 71 0.021
production of molecular mediator of immune response GO:0002440 103 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
nitrogen compound transport GO:0071705 271 0.021
mesenchymal cell development GO:0014031 93 0.021
translation GO:0006412 93 0.021
wound healing GO:0042060 157 0.021
regulation of tyrosine phosphorylation of stat protein GO:0042509 20 0.021
organic anion transport GO:0015711 137 0.021
leukocyte apoptotic process GO:0071887 71 0.021
protein acylation GO:0043543 64 0.021
organelle fission GO:0048285 170 0.021
lymphocyte apoptotic process GO:0070227 54 0.021
epithelial cell proliferation GO:0050673 174 0.021
organophosphate biosynthetic process GO:0090407 122 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
regulation of protein transport GO:0051223 163 0.020
negative regulation of inflammatory response GO:0050728 61 0.020
cytokine biosynthetic process GO:0042089 68 0.020
circulatory system process GO:0003013 197 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.020
lipid biosynthetic process GO:0008610 179 0.020
meiotic cell cycle GO:0051321 122 0.020
oocyte construction GO:0007308 2 0.020
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.020
protein catabolic process GO:0030163 221 0.020
response to reactive oxygen species GO:0000302 56 0.020
response to extracellular stimulus GO:0009991 127 0.019
response to amino acid GO:0043200 37 0.019
positive regulation of t cell differentiation GO:0045582 52 0.019
regulation of cell cycle GO:0051726 281 0.019
histone modification GO:0016570 159 0.019
positive regulation of cytokine biosynthetic process GO:0042108 40 0.019
mitochondrion organization GO:0007005 134 0.019
dna replication GO:0006260 52 0.019
multicellular organismal homeostasis GO:0048871 164 0.019
ameboidal type cell migration GO:0001667 128 0.019
regulation of alpha beta t cell activation GO:0046634 53 0.019
covalent chromatin modification GO:0016569 163 0.019
regulation of protein complex assembly GO:0043254 83 0.018
regulation of proteasomal protein catabolic process GO:0061136 46 0.018
positive regulation of lymphocyte differentiation GO:0045621 61 0.018
intrinsic apoptotic signaling pathway GO:0097193 132 0.018
positive regulation of mitotic cell cycle GO:0045931 41 0.018
anatomical structure homeostasis GO:0060249 145 0.018
peptide transport GO:0015833 133 0.018
ncrna processing GO:0034470 26 0.018
heart morphogenesis GO:0003007 178 0.018
sensory organ morphogenesis GO:0090596 242 0.018
protein targeting GO:0006605 143 0.018
response to hypoxia GO:0001666 58 0.018
response to acid chemical GO:0001101 111 0.018
regulation of ossification GO:0030278 112 0.018
cation transport GO:0006812 399 0.018
regulation of response to cytokine stimulus GO:0060759 23 0.018
negative regulation of neuron projection development GO:0010977 50 0.018
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.017
cell migration involved in gastrulation GO:0042074 13 0.017
embryonic epithelial tube formation GO:0001838 130 0.017
skeletal muscle organ development GO:0060538 163 0.017
cellular response to amino acid stimulus GO:0071230 29 0.017
regulation of cell size GO:0008361 72 0.017
positive regulation of leukocyte proliferation GO:0070665 73 0.017
negative regulation of neuron apoptotic process GO:0043524 92 0.017
peptide secretion GO:0002790 114 0.017
sensory perception GO:0007600 245 0.017
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.017
protein localization to nucleus GO:0034504 121 0.016
t helper 1 cell differentiation GO:0045063 13 0.016
humoral immune response GO:0006959 57 0.016
thymocyte apoptotic process GO:0070242 19 0.016
negative regulation of neuron differentiation GO:0045665 101 0.016
gonad development GO:0008406 141 0.016
cardiocyte differentiation GO:0035051 87 0.016
regulation of protein processing GO:0070613 96 0.016
alpha amino acid metabolic process GO:1901605 59 0.016
positive regulation of organelle organization GO:0010638 128 0.016
inositol lipid mediated signaling GO:0048017 41 0.016
regulation of lymphocyte mediated immunity GO:0002706 84 0.016
intracellular receptor signaling pathway GO:0030522 74 0.016
actin filament based movement GO:0030048 23 0.016
lipid transport GO:0006869 98 0.016
tissue regeneration GO:0042246 22 0.016
regulation of cell motility GO:2000145 236 0.016
renal system development GO:0072001 225 0.016
positive regulation of adaptive immune response GO:0002821 61 0.016
regulation of t helper 1 type immune response GO:0002825 17 0.016
negative regulation of immune effector process GO:0002698 55 0.016
response to glucocorticoid GO:0051384 20 0.016
negative regulation of ossification GO:0030279 49 0.016
tissue homeostasis GO:0001894 115 0.016
labyrinthine layer development GO:0060711 49 0.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 3 0.015
synapse organization GO:0050808 125 0.015
regulation of cell adhesion GO:0030155 154 0.015
nucleotide metabolic process GO:0009117 332 0.015
negative regulation of synapse assembly GO:0051964 3 0.015
regulation of b cell activation GO:0050864 81 0.015
negative regulation of tyrosine phosphorylation of stat protein GO:0042532 3 0.015
immunoglobulin mediated immune response GO:0016064 69 0.015
regulation of cellular component size GO:0032535 121 0.015
transmembrane transport GO:0055085 412 0.015
cellular response to alcohol GO:0097306 23 0.015

Ptpn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
musculoskeletal system disease DOID:17 0 0.019
immune system disease DOID:2914 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016