Mus musculus

23 known processes

Tapbp

TAP binding protein

(Aliases: TPN,D17Wsu91e)

Tapbp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of t cell mediated cytotoxicity GO:0001916 15 1.000
negative regulation of natural killer cell mediated immunity GO:0002716 5 1.000
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 1.000
antigen processing and presentation via mhc class ib GO:0002475 8 0.998
regulation of t cell mediated cytotoxicity GO:0001914 18 0.997
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.996
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.996
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.995
regulation of natural killer cell mediated immunity GO:0002715 19 0.992
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.992
t cell mediated cytotoxicity GO:0001913 26 0.987
natural killer cell mediated immunity GO:0002228 29 0.984
natural killer cell mediated cytotoxicity GO:0042267 29 0.982
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.981
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway GO:0002488 2 0.972
antigen processing and presentation of endogenous antigen GO:0019883 6 0.955
antigen processing and presentation of exogenous antigen GO:0019884 26 0.955
interspecies interaction between organisms GO:0044419 83 0.951
antigen processing and presentation GO:0019882 47 0.951
myosin filament organization GO:0031033 3 0.951
positive regulation of cell killing GO:0031343 33 0.941
intracellular transport of virus GO:0075733 1 0.937
viral process GO:0016032 41 0.937
gene silencing by rna GO:0031047 19 0.934
antigen processing and presentation of exogenous protein antigen via mhc class ib tap dependent GO:0002481 3 0.934
cell killing GO:0001906 67 0.930
antigen processing and presentation of peptide antigen GO:0048002 29 0.924
leukocyte mediated cytotoxicity GO:0001909 62 0.901
myosin filament assembly GO:0031034 2 0.899
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.898
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.886
lymphocyte mediated immunity GO:0002449 139 0.880
interaction with host GO:0051701 22 0.875
regulation of cell killing GO:0031341 40 0.871
antigen processing and presentation of endogenous peptide antigen GO:0002483 6 0.870
antigen processing and presentation of exogenous peptide antigen via mhc class ib GO:0002477 3 0.867
posttranscriptional gene silencing GO:0016441 10 0.866
adaptive immune response GO:0002250 155 0.863
antigen processing and presentation of peptide antigen via mhc class ib GO:0002428 5 0.861
lysosomal transport GO:0007041 10 0.851
transport of virus GO:0046794 1 0.842
negative regulation of innate immune response GO:0045824 17 0.838
striated muscle myosin thick filament assembly GO:0071688 1 0.833
viral life cycle GO:0019058 36 0.821
leukocyte mediated immunity GO:0002443 174 0.814
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.814
iron ion import into cell GO:0097459 4 0.792
innate immune response GO:0045087 157 0.789
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.768
cellular component assembly involved in morphogenesis GO:0010927 139 0.763
regulation of leukocyte mediated immunity GO:0002703 104 0.746
posttranscriptional gene silencing by rna GO:0035194 10 0.739
regulation of innate immune response GO:0045088 91 0.725
rna interference GO:0016246 2 0.724
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap dependent GO:0002485 3 0.709
regulation of lymphocyte mediated immunity GO:0002706 84 0.703
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.697
gene silencing GO:0016458 38 0.688
multicellular organism growth GO:0035264 161 0.677
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway tap dependent GO:0002489 2 0.665
t cell mediated immunity GO:0002456 50 0.615
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.605
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.595
regulation of adaptive immune response GO:0002819 90 0.592
intracellular protein transport GO:0006886 204 0.578
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.549
negative regulation of immune system process GO:0002683 209 0.538
protection from natural killer cell mediated cytotoxicity GO:0042270 2 0.524
organelle assembly GO:0070925 177 0.509
response to molecule of bacterial origin GO:0002237 143 0.508
positive regulation of innate immune response GO:0045089 80 0.504
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.499
positive regulation of t cell mediated immunity GO:0002711 24 0.492
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.480
actomyosin structure organization GO:0031032 56 0.462
positive regulation of leukocyte mediated immunity GO:0002705 70 0.448
negative regulation of defense response GO:0031348 77 0.434
positive regulation of type i interferon production GO:0032481 14 0.433
positive regulation of adaptive immune response GO:0002821 61 0.427
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.422
negative regulation of immune effector process GO:0002698 55 0.407
positive regulation of immune effector process GO:0002699 107 0.388
cd4 positive alpha beta t cell lineage commitment GO:0043373 6 0.377
muscle cell development GO:0055001 133 0.374
posttranscriptional regulation of gene expression GO:0010608 155 0.343
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.337
cellular response to interferon gamma GO:0071346 25 0.335
myofibril assembly GO:0030239 34 0.330
cytoplasmic transport GO:0016482 234 0.328
regulation of t cell mediated immunity GO:0002709 34 0.323
regulation of defense response GO:0031347 233 0.323
actin cytoskeleton organization GO:0030036 220 0.321
lymphocyte activation involved in immune response GO:0002285 93 0.267
immune effector process GO:0002252 321 0.252
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.250
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.241
carbohydrate derivative catabolic process GO:1901136 231 0.239
negative regulation of leukocyte mediated immunity GO:0002704 29 0.238
cell activation involved in immune response GO:0002263 126 0.237
iron ion import GO:0097286 5 0.230
female sex differentiation GO:0046660 84 0.229
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.228
cell adhesion GO:0007155 329 0.214
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.208
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.206
interleukin 4 mediated signaling pathway GO:0035771 2 0.204
regulation of mast cell differentiation GO:0060375 3 0.202
epithelial cell proliferation GO:0050673 174 0.199
response to interleukin 4 GO:0070670 23 0.194
interleukin 17 production GO:0032620 11 0.193
regulation of antigen processing and presentation GO:0002577 10 0.186
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.183
atp metabolic process GO:0046034 75 0.180
cellular protein complex assembly GO:0043623 116 0.178
t helper 17 cell lineage commitment GO:0072540 4 0.171
positive regulation of mast cell differentiation GO:0060376 1 0.171
negative regulation of regulatory t cell differentiation GO:0045590 2 0.171
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.169
nucleoside catabolic process GO:0009164 206 0.166
multicellular organismal homeostasis GO:0048871 164 0.165
peptide transport GO:0015833 133 0.162
positive regulation of defense response GO:0031349 124 0.159
negative regulation of cell proliferation GO:0008285 296 0.159
positive regulation of peptidase activity GO:0010952 49 0.153
response to interferon gamma GO:0034341 34 0.148
iron ion homeostasis GO:0055072 36 0.143
alpha beta t cell activation GO:0046631 91 0.142
atp catabolic process GO:0006200 55 0.140
glycosyl compound metabolic process GO:1901657 246 0.139
regulation of proteolysis GO:0030162 164 0.138
macrophage fusion GO:0034238 3 0.137
citrate metabolic process GO:0006101 3 0.134
muscle cell differentiation GO:0042692 261 0.130
ribonucleoside triphosphate metabolic process GO:0009199 220 0.130
nucleotide catabolic process GO:0009166 217 0.129
b cell mediated immunity GO:0019724 71 0.128
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 5 0.128
ribonucleotide metabolic process GO:0009259 291 0.127
regulation of antigen processing and presentation of peptide antigen GO:0002583 1 0.127
movement in host environment GO:0052126 15 0.127
reactive oxygen species biosynthetic process GO:1903409 8 0.125
response to type i interferon GO:0034340 12 0.124
nucleoside triphosphate catabolic process GO:0009143 205 0.119
negative regulation of erythrocyte differentiation GO:0045647 5 0.118
striated muscle cell development GO:0055002 125 0.118
protein catabolic process GO:0030163 221 0.117
heterocycle catabolic process GO:0046700 280 0.115
cellular response to dna damage stimulus GO:0006974 207 0.114
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.114
positive regulation of cytokine biosynthetic process GO:0042108 40 0.114
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.113
sulfur compound metabolic process GO:0006790 100 0.113
purine nucleoside triphosphate catabolic process GO:0009146 203 0.111
regulation of t cell activation GO:0050863 170 0.111
positive regulation of interferon gamma production GO:0032729 39 0.111
nucleobase containing small molecule metabolic process GO:0055086 352 0.110
ribose phosphate metabolic process GO:0019693 291 0.108
hormone metabolic process GO:0042445 86 0.106
response to cadmium ion GO:0046686 8 0.105
negative regulation of defense response to virus by host GO:0050689 1 0.103
regulation of leukocyte proliferation GO:0070663 121 0.103
positive regulation of tolerance induction GO:0002645 8 0.103
immunoglobulin mediated immune response GO:0016064 69 0.103
tolerance induction dependent upon immune response GO:0002461 1 0.103
purine ribonucleotide catabolic process GO:0009154 208 0.100
response to interleukin 15 GO:0070672 3 0.100
cellular nitrogen compound catabolic process GO:0044270 280 0.099
myeloid cell homeostasis GO:0002262 114 0.099
negative regulation of viral process GO:0048525 23 0.098
production of molecular mediator of immune response GO:0002440 103 0.097
t helper 1 cell lineage commitment GO:0002296 2 0.096
regulation of interferon gamma production GO:0032649 57 0.096
male sex differentiation GO:0046661 109 0.096
cellular macromolecule catabolic process GO:0044265 206 0.095
purine nucleoside monophosphate metabolic process GO:0009126 81 0.094
lymphocyte proliferation GO:0046651 164 0.094
t cell activation GO:0042110 289 0.093
ribonucleoside catabolic process GO:0042454 206 0.092
aromatic compound catabolic process GO:0019439 286 0.092
response to organic cyclic compound GO:0014070 198 0.092
t cell activation involved in immune response GO:0002286 43 0.090
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.090
stem cell differentiation GO:0048863 268 0.088
negative regulation of t cell differentiation GO:0045581 23 0.088
taurine metabolic process GO:0019530 4 0.087
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.087
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.085
amide transport GO:0042886 138 0.085
valine metabolic process GO:0006573 4 0.082
dna metabolic process GO:0006259 303 0.080
leukocyte differentiation GO:0002521 342 0.080
positive regulation of response to cytokine stimulus GO:0060760 11 0.079
development of secondary male sexual characteristics GO:0046544 3 0.078
endocytosis GO:0006897 168 0.078
epidermis development GO:0008544 187 0.077
regulation of cytokine biosynthetic process GO:0042035 59 0.077
jak stat cascade involved in growth hormone signaling pathway GO:0060397 4 0.077
regulation of macrophage fusion GO:0034239 3 0.076
vacuolar transport GO:0007034 11 0.076
regulation of reactive oxygen species metabolic process GO:2000377 40 0.076
negative regulation of interferon beta production GO:0032688 3 0.075
creatinine metabolic process GO:0046449 3 0.073
nucleoside triphosphate metabolic process GO:0009141 230 0.073
isoleucine metabolic process GO:0006549 4 0.073
alpha beta t cell activation involved in immune response GO:0002287 31 0.073
defense response to protozoan GO:0042832 25 0.073
cellular amino acid metabolic process GO:0006520 103 0.072
regulation of lymphocyte activation GO:0051249 240 0.072
regulation of defense response to virus by host GO:0050691 8 0.071
macromolecule catabolic process GO:0009057 281 0.071
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.068
regulation of hormone levels GO:0010817 211 0.067
mast cell apoptotic process GO:0033024 5 0.067
positive t cell selection GO:0043368 23 0.065
cytokine biosynthetic process GO:0042089 68 0.064
purine nucleoside catabolic process GO:0006152 205 0.064
ribonucleoside monophosphate catabolic process GO:0009158 57 0.064
type i interferon signaling pathway GO:0060337 10 0.063
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.062
covalent chromatin modification GO:0016569 163 0.062
defense response to bacterium GO:0042742 119 0.062
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.062
positive regulation of proteolysis GO:0045862 85 0.061
cytokine metabolic process GO:0042107 71 0.061
protein modification by small protein conjugation or removal GO:0070647 207 0.061
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.060
nucleotide metabolic process GO:0009117 332 0.060
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.060
negative regulation of cell activation GO:0050866 111 0.059
gene silencing by mirna GO:0035195 10 0.059
myeloid dendritic cell differentiation GO:0043011 16 0.059
maintenance of location GO:0051235 89 0.058
cellular lactam metabolic process GO:0072338 3 0.057
regulation of mast cell apoptotic process GO:0033025 5 0.057
positive regulation of mast cell proliferation GO:0070668 3 0.055
cellular ketone metabolic process GO:0042180 84 0.054
translation GO:0006412 93 0.053
progesterone metabolic process GO:0042448 4 0.053
nucleoside phosphate catabolic process GO:1901292 222 0.052
regulation of interferon beta biosynthetic process GO:0045357 4 0.052
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.051
purine ribonucleoside metabolic process GO:0046128 241 0.051
ribonucleoside triphosphate catabolic process GO:0009203 199 0.051
ribonucleoside metabolic process GO:0009119 245 0.051
glycosyl compound catabolic process GO:1901658 206 0.050
cation transport GO:0006812 399 0.050
regulation of cytokine production GO:0001817 266 0.050
negative regulation of cell killing GO:0031342 8 0.050
immune response activating signal transduction GO:0002757 116 0.050
metal ion homeostasis GO:0055065 189 0.049
histone h4 acetylation GO:0043967 10 0.049
epithelial cell development GO:0002064 159 0.049
cd4 positive alpha beta t cell activation GO:0035710 45 0.049
response to endoplasmic reticulum stress GO:0034976 53 0.048
carbohydrate metabolic process GO:0005975 230 0.048
organic cyclic compound catabolic process GO:1901361 295 0.048
regulation of multi organism process GO:0043900 111 0.047
positive regulation of actin filament polymerization GO:0030838 26 0.047
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.046
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.046
viral genome replication GO:0019079 17 0.045
nucleoside metabolic process GO:0009116 246 0.045
jak stat cascade GO:0007259 42 0.045
response to lipopolysaccharide GO:0032496 128 0.044
female gonad development GO:0008585 71 0.044
negative regulation of t cell activation GO:0050868 65 0.044
cellular response to lipopolysaccharide GO:0071222 77 0.043
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.043
apoptotic signaling pathway GO:0097190 306 0.043
calcium ion transport GO:0006816 159 0.043
tricarboxylic acid metabolic process GO:0072350 5 0.042
ribonucleoside monophosphate metabolic process GO:0009161 80 0.042
reactive nitrogen species metabolic process GO:2001057 0 0.042
cellular amine metabolic process GO:0044106 44 0.042
positive regulation of antigen processing and presentation GO:0002579 10 0.041
modification dependent protein catabolic process GO:0019941 133 0.041
reactive oxygen species metabolic process GO:0072593 84 0.041
nucleoside phosphate metabolic process GO:0006753 338 0.041
regulation of t cell proliferation GO:0042129 92 0.041
regulation of natural killer cell differentiation GO:0032823 11 0.041
purine containing compound catabolic process GO:0072523 213 0.040
leukocyte proliferation GO:0070661 172 0.040
regulation of cell adhesion GO:0030155 154 0.040
interferon gamma mediated signaling pathway GO:0060333 5 0.040
response to dsrna GO:0043331 30 0.040
rhythmic process GO:0048511 174 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
purine nucleoside metabolic process GO:0042278 241 0.039
nitrogen compound transport GO:0071705 271 0.039
cd8 positive alpha beta t cell differentiation GO:0043374 9 0.039
negative regulation of macrophage fusion GO:0034240 1 0.038
carbohydrate catabolic process GO:0016052 32 0.038
glycoprotein metabolic process GO:0009100 116 0.038
cytokine mediated signaling pathway GO:0019221 115 0.038
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.038
nucleoside monophosphate metabolic process GO:0009123 85 0.037
t cell selection GO:0045058 34 0.037
regulation of cell motility GO:2000145 236 0.037
feeding behavior GO:0007631 62 0.037
regulation of cellular component biogenesis GO:0044087 181 0.037
endoplasmic reticulum calcium ion homeostasis GO:0032469 11 0.037
transition metal ion transport GO:0000041 38 0.036
regulation of alpha beta t cell proliferation GO:0046640 18 0.036
chromatin organization GO:0006325 206 0.036
urogenital system development GO:0001655 261 0.036
protein polymerization GO:0051258 57 0.035
ion transmembrane transport GO:0034220 361 0.035
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.035
regulation of cell migration GO:0030334 219 0.035
negative regulation of syncytium formation by plasma membrane fusion GO:0034242 5 0.035
glial cell apoptotic process GO:0034349 3 0.035
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.034
mucosal associated lymphoid tissue development GO:0048537 12 0.034
regulation of dna templated transcription initiation GO:2000142 7 0.034
inorganic cation import into cell GO:0098659 4 0.034
immune response regulating signaling pathway GO:0002764 125 0.034
protein modification by small protein conjugation GO:0032446 187 0.034
positive regulation of natural killer cell proliferation GO:0032819 2 0.034
intrinsic apoptotic signaling pathway GO:0097193 132 0.033
b cell activation involved in immune response GO:0002312 50 0.033
cellular ion homeostasis GO:0006873 165 0.033
creatine metabolic process GO:0006600 4 0.033
peptidyl lysine methylation GO:0018022 29 0.033
regulation of nitric oxide biosynthetic process GO:0045428 18 0.032
response to peptide GO:1901652 136 0.032
t cell differentiation in thymus GO:0033077 77 0.031
development of primary sexual characteristics GO:0045137 143 0.031
monocarboxylic acid metabolic process GO:0032787 191 0.031
positive regulation of lymphocyte activation GO:0051251 140 0.031
peptidyl amino acid modification GO:0018193 336 0.030
negative regulation of cell migration GO:0030336 59 0.030
lipid localization GO:0010876 126 0.030
cellular response to peptide GO:1901653 92 0.030
keratinocyte differentiation GO:0030216 48 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.030
cellular response to biotic stimulus GO:0071216 92 0.030
cytokine production GO:0001816 319 0.029
somatic cell dna recombination GO:0016444 51 0.029
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.029
alpha beta t cell differentiation GO:0046632 69 0.029
regulation of homeostatic process GO:0032844 182 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
eye photoreceptor cell differentiation GO:0001754 41 0.029
ovulation cycle GO:0042698 59 0.029
t cell proliferation GO:0042098 120 0.028
muscle tissue development GO:0060537 308 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
response to metal ion GO:0010038 47 0.028
purine nucleotide catabolic process GO:0006195 211 0.028
regulation of endopeptidase activity GO:0052548 89 0.028
positive regulation of rig i signaling pathway GO:1900246 1 0.028
negative regulation of interferon beta biosynthetic process GO:0045358 1 0.027
cell type specific apoptotic process GO:0097285 268 0.027
negative regulation of viral release from host cell GO:1902187 6 0.027
regulation of lymphocyte differentiation GO:0045619 107 0.026
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.026
negative regulation of cytokine production GO:0001818 84 0.025
mast cell proliferation GO:0070662 4 0.025
macromolecule methylation GO:0043414 120 0.025
t helper cell lineage commitment GO:0002295 6 0.025
peptidyl tyrosine modification GO:0018212 145 0.025
cation homeostasis GO:0055080 212 0.025
protein ubiquitination GO:0016567 171 0.025
transition metal ion homeostasis GO:0055076 54 0.025
regulation of actin nucleation GO:0051125 4 0.025
positive regulation of hydrolase activity GO:0051345 148 0.024
positive regulation of isotype switching to ige isotypes GO:0048295 4 0.024
succinate metabolic process GO:0006105 4 0.024
leukocyte activation involved in immune response GO:0002366 126 0.024
histone modification GO:0016570 159 0.024
gonad development GO:0008406 141 0.024
gland development GO:0048732 330 0.024
keratinocyte proliferation GO:0043616 21 0.024
macrophage migration inhibitory factor signaling pathway GO:0035691 2 0.024
chromatin modification GO:0016568 187 0.024
positive regulation of response to wounding GO:1903036 66 0.024
positive regulation of inflammatory response GO:0050729 47 0.023
iron ion transport GO:0006826 17 0.023
organophosphate catabolic process GO:0046434 232 0.023
regulation of natural killer cell proliferation GO:0032817 2 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
natural killer cell proliferation GO:0001787 3 0.023
blood vessel morphogenesis GO:0048514 285 0.023
negative regulation of mast cell apoptotic process GO:0033026 4 0.023
development of primary female sexual characteristics GO:0046545 73 0.022
positive regulation of activated t cell proliferation GO:0042104 8 0.022
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.022
positive regulation of cytokine production GO:0001819 174 0.022
nuclear import GO:0051170 95 0.022
cytokine production involved in immune response GO:0002367 34 0.022
stem cell development GO:0048864 219 0.022
molting cycle GO:0042303 90 0.022
regulation of vasculature development GO:1901342 88 0.022
negative regulation of homeostatic process GO:0032845 71 0.022
regulation of cell activation GO:0050865 289 0.022
somatic diversification of immune receptors GO:0002200 53 0.022
rac protein signal transduction GO:0016601 13 0.022
response to protozoan GO:0001562 28 0.022
regulation of type 2 immune response GO:0002828 18 0.022
regulation of lipid metabolic process GO:0019216 118 0.022
purine nucleotide metabolic process GO:0006163 302 0.021
regulation of dna binding GO:0051101 39 0.021
isotype switching to ige isotypes GO:0048289 7 0.021
response to inorganic substance GO:0010035 96 0.021
germ cell development GO:0007281 185 0.021
regulation of membrane potential GO:0042391 192 0.021
purine nucleoside monophosphate catabolic process GO:0009128 58 0.021
negative regulation of leukocyte differentiation GO:1902106 51 0.021
myeloid cell differentiation GO:0030099 233 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
inflammatory response GO:0006954 244 0.021
notch signaling pathway GO:0007219 71 0.021
hormone biosynthetic process GO:0042446 16 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.020
protein targeting GO:0006605 143 0.020
regulation of alpha beta t cell activation GO:0046634 53 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
fatty acid metabolic process GO:0006631 121 0.020
lipid homeostasis GO:0055088 63 0.020
negative regulation of cell motility GO:2000146 61 0.020
prostate gland development GO:0030850 48 0.020
regulation of chromosome organization GO:0033044 83 0.020
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.019
negative regulation of osteoblast proliferation GO:0033689 4 0.019
b cell activation GO:0042113 161 0.019
negative regulation of nervous system development GO:0051961 156 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.019
t cell differentiation GO:0030217 174 0.019
somatic diversification of immunoglobulins GO:0016445 43 0.019
protein import GO:0017038 101 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
homeostasis of number of cells GO:0048872 210 0.019
neuronal action potential GO:0019228 54 0.019
b cell differentiation GO:0030183 78 0.019
extracellular structure organization GO:0043062 148 0.019
positive regulation of glutamate secretion GO:0014049 2 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
response to peptide hormone GO:0043434 127 0.018
renal system development GO:0072001 225 0.018
lymphocyte differentiation GO:0030098 242 0.018
glycosylation GO:0070085 62 0.018
glucose homeostasis GO:0042593 128 0.018
extracellular matrix organization GO:0030198 147 0.018
regulation of angiogenesis GO:0045765 81 0.018
positive regulation of t cell proliferation GO:0042102 52 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
nuclear membrane organization GO:0071763 4 0.018
interleukin 1 production GO:0032612 31 0.018
generation of precursor metabolites and energy GO:0006091 103 0.018
t helper 17 cell differentiation GO:0072539 7 0.018
stem cell maintenance GO:0019827 130 0.018
negative regulation of cytokine biosynthetic process GO:0042036 13 0.018
regulation of b cell mediated immunity GO:0002712 37 0.018
glycolytic process GO:0006096 20 0.018
positive regulation of cell activation GO:0050867 158 0.018
regulation of body fluid levels GO:0050878 162 0.018
regulation of toll like receptor signaling pathway GO:0034121 20 0.018
neuromuscular process GO:0050905 99 0.018
ear development GO:0043583 200 0.017
photoreceptor cell differentiation GO:0046530 52 0.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.017
regulation of neuron migration GO:2001222 22 0.017
response to organonitrogen compound GO:0010243 246 0.017
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 2 0.017
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
nucleoside monophosphate catabolic process GO:0009125 59 0.017
growth hormone receptor signaling pathway GO:0060396 7 0.017
regulation of b cell differentiation GO:0045577 23 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
leukocyte apoptotic process GO:0071887 71 0.017
positive regulation of actin nucleation GO:0051127 3 0.017
regulation of viral genome replication GO:0045069 13 0.017
i kappab kinase nf kappab signaling GO:0007249 85 0.017
regulation of peptidase activity GO:0052547 96 0.017
protein localization to organelle GO:0033365 185 0.017
peptidyl lysine modification GO:0018205 77 0.017
protein localization to nucleus GO:0034504 121 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
spermatogenesis GO:0007283 284 0.017

Tapbp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 0 0.929
severe combined immunodeficiency DOID:627 0 0.929
combined t cell and b cell immunodeficiency DOID:628 0 0.929
immune system disease DOID:2914 0 0.929
disease of anatomical entity DOID:7 0 0.929
nervous system disease DOID:863 0 0.059
central nervous system disease DOID:331 0 0.030
disease of metabolism DOID:0014667 0 0.022
bone remodeling disease DOID:0080005 0 0.017
bone disease DOID:0080001 0 0.017
osteopetrosis DOID:13533 0 0.017
musculoskeletal system disease DOID:17 0 0.017
connective tissue disease DOID:65 0 0.017
osteosclerosis DOID:4254 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017