Mus musculus

50 known processes

Icosl

icos ligand

(Aliases: B7-H2,BG071784,Icoslg,LICOS,B7RP-1,mKIAA0653,GL50,KIAA0653,GI50,B7h,ICOS-L,GL50-B,Ly115l,AU044799)

Icosl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 45 0.162
cellular amino acid metabolic process GO:0006520 103 0.150
inflammatory response GO:0006954 244 0.146
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.138
cytokine production GO:0001816 319 0.133
organic cyclic compound catabolic process GO:1901361 295 0.117
cation transport GO:0006812 399 0.117
t cell activation GO:0042110 289 0.116
Mouse
muscle cell differentiation GO:0042692 261 0.113
aromatic compound catabolic process GO:0019439 286 0.112
heterocycle catabolic process GO:0046700 280 0.110
cellular ketone metabolic process GO:0042180 84 0.106
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.106
cellular nitrogen compound catabolic process GO:0044270 280 0.101
cellular amine metabolic process GO:0044106 44 0.101
purine nucleotide catabolic process GO:0006195 211 0.099
muscle tissue development GO:0060537 308 0.095
nucleoside phosphate metabolic process GO:0006753 338 0.089
positive regulation of protein modification process GO:0031401 299 0.089
negative regulation of immune system process GO:0002683 209 0.088
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.088
activation of immune response GO:0002253 138 0.086
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.085
purine nucleotide metabolic process GO:0006163 302 0.085
nucleotide metabolic process GO:0009117 332 0.084
negative regulation of protein metabolic process GO:0051248 282 0.083
Mouse
negative regulation of cell proliferation GO:0008285 296 0.082
Mouse
ribonucleoside metabolic process GO:0009119 245 0.081
regulation of cytokine production GO:0001817 266 0.081
ras protein signal transduction GO:0007265 77 0.081
lymphocyte differentiation GO:0030098 242 0.080
Mouse
sequestering of metal ion GO:0051238 19 0.077
immune effector process GO:0002252 321 0.077
Mouse
positive regulation of cell activation GO:0050867 158 0.077
Mouse
axonogenesis GO:0007409 274 0.076
striated muscle tissue development GO:0014706 293 0.075
transmembrane transport GO:0055085 412 0.074
chromatin organization GO:0006325 206 0.073
purine containing compound catabolic process GO:0072523 213 0.073
divalent metal ion transport GO:0070838 172 0.071
chromatin modification GO:0016568 187 0.070
purine nucleoside triphosphate catabolic process GO:0009146 203 0.070
regulation of secretion GO:0051046 274 0.070
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.069
purine nucleoside triphosphate metabolic process GO:0009144 226 0.069
leukocyte differentiation GO:0002521 342 0.069
Mouse
response to growth factor GO:0070848 198 0.069
myeloid cell differentiation GO:0030099 233 0.068
small gtpase mediated signal transduction GO:0007264 97 0.067
organelle fission GO:0048285 170 0.067
regulation of cellular component biogenesis GO:0044087 181 0.067
regulation of cellular amino acid metabolic process GO:0006521 5 0.066
cellular response to growth factor stimulus GO:0071363 197 0.065
reactive oxygen species metabolic process GO:0072593 84 0.065
ribonucleoside catabolic process GO:0042454 206 0.064
renal system development GO:0072001 225 0.064
glycosyl compound catabolic process GO:1901658 206 0.064
regulation of lymphocyte activation GO:0051249 240 0.063
Mouse
nucleoside catabolic process GO:0009164 206 0.063
divalent inorganic cation transport GO:0072511 178 0.062
carbohydrate derivative catabolic process GO:1901136 231 0.062
nucleotide catabolic process GO:0009166 217 0.062
g protein coupled receptor signaling pathway GO:0007186 243 0.062
regulation of homeostatic process GO:0032844 182 0.062
homeostasis of number of cells GO:0048872 210 0.060
glycosyl compound metabolic process GO:1901657 246 0.060
inorganic cation transmembrane transport GO:0098662 207 0.060
positive regulation of cellular amine metabolic process GO:0033240 5 0.060
purine ribonucleotide metabolic process GO:0009150 290 0.059
positive regulation of cell development GO:0010720 237 0.059
nucleoside phosphate catabolic process GO:1901292 222 0.059
organophosphate catabolic process GO:0046434 232 0.058
organonitrogen compound catabolic process GO:1901565 264 0.058
purine containing compound metabolic process GO:0072521 311 0.058
epithelial tube morphogenesis GO:0060562 303 0.057
skeletal muscle organ development GO:0060538 163 0.056
positive regulation of programmed cell death GO:0043068 218 0.056
regulation of cellular catabolic process GO:0031329 242 0.056
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.055
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.055
purine ribonucleoside catabolic process GO:0046130 205 0.055
cell fate commitment GO:0045165 210 0.055
regulation of hydrolase activity GO:0051336 246 0.055
regulation of apoptotic signaling pathway GO:2001233 197 0.054
regulation of organelle organization GO:0033043 289 0.054
ribonucleotide catabolic process GO:0009261 208 0.054
skin development GO:0043588 220 0.054
purine ribonucleotide catabolic process GO:0009154 208 0.054
nucleoside triphosphate metabolic process GO:0009141 230 0.053
cell adhesion GO:0007155 329 0.053
negative regulation of cellular amine metabolic process GO:0033239 1 0.052
sequestering of calcium ion GO:0051208 18 0.052
extracellular structure organization GO:0043062 148 0.052
negative regulation of intracellular signal transduction GO:1902532 167 0.051
Mouse
regulation of secretion by cell GO:1903530 249 0.051
Mouse
organelle localization GO:0051640 179 0.051
rho protein signal transduction GO:0007266 32 0.051
nucleoside metabolic process GO:0009116 246 0.051
ion transmembrane transport GO:0034220 361 0.050
cellular response to cytokine stimulus GO:0071345 189 0.050
regulation of kinase activity GO:0043549 249 0.049
ribonucleoside triphosphate metabolic process GO:0009199 220 0.049
negative regulation of cytokine production GO:0001818 84 0.049
Mouse
mitotic cell cycle process GO:1903047 159 0.048
Mouse
leukocyte migration GO:0050900 124 0.048
nuclear division GO:0000280 158 0.048
regulation of defense response GO:0031347 233 0.047
Mouse
maintenance of location GO:0051235 89 0.047
cellular response to biotic stimulus GO:0071216 92 0.047
negative regulation of cellular protein metabolic process GO:0032269 247 0.047
positive regulation of nervous system development GO:0051962 221 0.046
regulation of cell cycle process GO:0010564 160 0.046
Mouse
response to lipopolysaccharide GO:0032496 128 0.046
cytokine secretion GO:0050663 72 0.046
Mouse
telencephalon development GO:0021537 186 0.046
positive regulation of cell death GO:0010942 224 0.046
forebrain development GO:0030900 302 0.046
alpha beta t cell differentiation GO:0046632 69 0.045
positive regulation of organelle organization GO:0010638 128 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.045
t cell differentiation GO:0030217 174 0.045
Mouse
angiogenesis GO:0001525 201 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
macromolecule catabolic process GO:0009057 281 0.045
positive regulation of neuron differentiation GO:0045666 141 0.045
lymphocyte proliferation GO:0046651 164 0.044
Mouse
regulation of protein transport GO:0051223 163 0.044
Mouse
kidney development GO:0001822 213 0.044
ribose phosphate metabolic process GO:0019693 291 0.044
peptidyl amino acid modification GO:0018193 336 0.043
wound healing GO:0042060 157 0.043
myotube differentiation GO:0014902 105 0.043
purine nucleoside metabolic process GO:0042278 241 0.043
b cell activation GO:0042113 161 0.043
Mouse
cation homeostasis GO:0055080 212 0.043
actin cytoskeleton organization GO:0030036 220 0.043
regulation of cell activation GO:0050865 289 0.042
Mouse
cellular homeostasis GO:0019725 240 0.042
developmental maturation GO:0021700 193 0.042
cation transmembrane transport GO:0098655 266 0.042
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.041
stem cell differentiation GO:0048863 268 0.041
guanosine containing compound metabolic process GO:1901068 144 0.041
cell growth GO:0016049 130 0.041
negative regulation of molecular function GO:0044092 258 0.041
ribonucleotide metabolic process GO:0009259 291 0.041
nucleoside triphosphate catabolic process GO:0009143 205 0.041
protein modification by small protein conjugation or removal GO:0070647 207 0.041
cellular lipid metabolic process GO:0044255 323 0.040
alpha beta t cell activation GO:0046631 91 0.040
adaptive immune response GO:0002250 155 0.040
cytoplasmic transport GO:0016482 234 0.040
cellular chemical homeostasis GO:0055082 215 0.040
regulation of cell cycle GO:0051726 281 0.040
Mouse
gliogenesis GO:0042063 141 0.040
purine ribonucleoside metabolic process GO:0046128 241 0.039
multicellular organismal homeostasis GO:0048871 164 0.039
regulation of mapk cascade GO:0043408 248 0.039
Mouse
gland development GO:0048732 330 0.039
response to molecule of bacterial origin GO:0002237 143 0.039
cellular response to lipopolysaccharide GO:0071222 77 0.039
inorganic ion transmembrane transport GO:0098660 234 0.039
stem cell proliferation GO:0072089 117 0.038
regulation of lymphocyte proliferation GO:0050670 117 0.038
Mouse
axon guidance GO:0007411 141 0.038
neuron projection guidance GO:0097485 141 0.037
mitotic cell cycle GO:0000278 195 0.037
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.037
establishment of organelle localization GO:0051656 122 0.037
regulation of neuron differentiation GO:0045664 281 0.037
mapk cascade GO:0000165 281 0.037
Mouse
extracellular matrix organization GO:0030198 147 0.037
learning or memory GO:0007611 148 0.037
regulation of cell migration GO:0030334 219 0.037
urogenital system development GO:0001655 261 0.037
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.036
negative regulation of protein modification process GO:0031400 163 0.036
regionalization GO:0003002 337 0.036
lymphocyte mediated immunity GO:0002449 139 0.036
cellular response to molecule of bacterial origin GO:0071219 83 0.035
regulation of body fluid levels GO:0050878 162 0.035
protein ubiquitination GO:0016567 171 0.035
regulation of striated muscle cell differentiation GO:0051153 81 0.035
chemotaxis GO:0006935 247 0.035
fat cell differentiation GO:0045444 160 0.035
protein modification by small protein conjugation GO:0032446 187 0.035
regulation of leukocyte proliferation GO:0070663 121 0.035
Mouse
blood vessel morphogenesis GO:0048514 285 0.035
regulation of mitotic cell cycle GO:0007346 126 0.035
Mouse
cell type specific apoptotic process GO:0097285 268 0.035
regulation of leukocyte differentiation GO:1902105 159 0.034
Mouse
cellular response to lipid GO:0071396 145 0.034
leukocyte mediated immunity GO:0002443 174 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.034
anion transport GO:0006820 177 0.034
microtubule based process GO:0007017 236 0.034
regulation of cellular response to stress GO:0080135 159 0.034
cell activation involved in immune response GO:0002263 126 0.034
actin filament organization GO:0007015 113 0.033
small molecule biosynthetic process GO:0044283 132 0.033
morphogenesis of a branching structure GO:0001763 203 0.033
purine nucleoside catabolic process GO:0006152 205 0.033
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.032
positive regulation of cellular catabolic process GO:0031331 148 0.032
positive regulation of gtp catabolic process GO:0033126 85 0.032
regulation of organ morphogenesis GO:2000027 144 0.032
connective tissue development GO:0061448 179 0.032
ossification GO:0001503 216 0.032
Mouse
immune response activating signal transduction GO:0002757 116 0.031
Mouse
cellular metal ion homeostasis GO:0006875 151 0.031
regulation of myotube differentiation GO:0010830 62 0.031
response to transforming growth factor beta GO:0071559 88 0.031
hematopoietic progenitor cell differentiation GO:0002244 143 0.031
guanosine containing compound catabolic process GO:1901069 144 0.031
positive regulation of secretion by cell GO:1903532 114 0.031
Mouse
immune response regulating signaling pathway GO:0002764 125 0.031
Mouse
synaptic transmission GO:0007268 329 0.031
cellular macromolecule catabolic process GO:0044265 206 0.030
regulation of ion transport GO:0043269 215 0.030
histone modification GO:0016570 159 0.030
protein localization to organelle GO:0033365 185 0.030
carbohydrate metabolic process GO:0005975 230 0.030
regulation of cytokine secretion GO:0050707 61 0.030
Mouse
regulation of intracellular transport GO:0032386 159 0.030
regulation of cell motility GO:2000145 236 0.029
placenta development GO:0001890 140 0.029
cellular protein complex assembly GO:0043623 116 0.029
positive regulation of cellular component biogenesis GO:0044089 94 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.029
microtubule cytoskeleton organization GO:0000226 157 0.029
intracellular protein transport GO:0006886 204 0.029
epidermis development GO:0008544 187 0.029
respiratory system development GO:0060541 190 0.029
negative regulation of cell development GO:0010721 169 0.029
regulation of ras gtpase activity GO:0032318 88 0.029
skeletal system development GO:0001501 356 0.029
gtp catabolic process GO:0006184 143 0.029
wnt signaling pathway GO:0016055 188 0.029
meiotic cell cycle GO:0051321 122 0.028
spermatogenesis GO:0007283 284 0.028
cellular ion homeostasis GO:0006873 165 0.028
regulation of anatomical structure size GO:0090066 178 0.028
calcium ion transport GO:0006816 159 0.028
positive regulation of cytokine production GO:0001819 174 0.028
cerebral cortex development GO:0021987 86 0.028
male gamete generation GO:0048232 285 0.028
metal ion homeostasis GO:0055065 189 0.028
single organism cell adhesion GO:0098602 156 0.028
methylation GO:0032259 134 0.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.028
negative regulation of phosphorylation GO:0042326 166 0.028
Mouse
regulation of system process GO:0044057 200 0.028
cell substrate adhesion GO:0031589 130 0.028
cd4 positive alpha beta t cell activation GO:0035710 45 0.028
negative regulation of nervous system development GO:0051961 156 0.028
cellular response to dna damage stimulus GO:0006974 207 0.027
regulation of protein kinase activity GO:0045859 232 0.027
negative regulation of lymphocyte activation GO:0051250 91 0.027
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.027
regulation of cellular component size GO:0032535 121 0.027
regulation of t cell differentiation GO:0045580 83 0.027
Mouse
embryonic epithelial tube formation GO:0001838 130 0.027
regulation of transferase activity GO:0051338 263 0.027
positive regulation of hydrolase activity GO:0051345 148 0.026
cellular calcium ion homeostasis GO:0006874 119 0.026
protein catabolic process GO:0030163 221 0.026
lymphocyte activation involved in immune response GO:0002285 93 0.026
neuron migration GO:0001764 122 0.026
regulation of muscle tissue development GO:1901861 97 0.026
response to organonitrogen compound GO:0010243 246 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
negative regulation of homeostatic process GO:0032845 71 0.026
leukocyte activation involved in immune response GO:0002366 126 0.026
regulation of cell projection organization GO:0031344 206 0.026
positive regulation of nucleotide catabolic process GO:0030813 88 0.026
regulation of cell adhesion GO:0030155 154 0.026
glycoprotein metabolic process GO:0009100 116 0.026
regulation of purine nucleotide catabolic process GO:0033121 122 0.026
t cell proliferation GO:0042098 120 0.026
Mouse
gene silencing GO:0016458 38 0.025
oxidation reduction process GO:0055114 342 0.025
myeloid cell homeostasis GO:0002262 114 0.025
epithelial tube formation GO:0072175 130 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
Mouse
neural precursor cell proliferation GO:0061351 121 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.025
camera type eye development GO:0043010 266 0.025
positive regulation of protein transport GO:0051222 93 0.025
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.025
Mouse
regulation of t cell activation GO:0050863 170 0.025
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.024
regulation of gtp catabolic process GO:0033124 113 0.024
response to inorganic substance GO:0010035 96 0.024
protein localization to nucleus GO:0034504 121 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
regulation of neuron projection development GO:0010975 169 0.024
lateral inhibition GO:0046331 1 0.024
covalent chromatin modification GO:0016569 163 0.024
muscle cell development GO:0055001 133 0.024
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.024
regulation of ion homeostasis GO:2000021 64 0.024
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.024
Mouse
positive regulation of gtpase activity GO:0043547 85 0.024
protein processing GO:0016485 163 0.024
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.024
regulation of lymphocyte differentiation GO:0045619 107 0.024
Mouse
interleukin 8 production GO:0032637 4 0.023
cognition GO:0050890 149 0.023
multi multicellular organism process GO:0044706 109 0.023
regulation of protein secretion GO:0050708 82 0.023
Mouse
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.023
branching morphogenesis of an epithelial tube GO:0048754 159 0.023
cellular response to organonitrogen compound GO:0071417 145 0.023
embryonic placenta development GO:0001892 98 0.023
regulation of myeloid cell differentiation GO:0045637 96 0.023
regulation of lymphocyte mediated immunity GO:0002706 84 0.023
compound eye development GO:0048749 1 0.023
positive regulation of rho gtpase activity GO:0032321 41 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
tendon cell differentiation GO:0035990 4 0.023
cell division GO:0051301 120 0.023
regulation of cytoplasmic transport GO:1903649 112 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.022
locomotory behavior GO:0007626 195 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
regulation of protein localization GO:0032880 231 0.022
Mouse
b cell differentiation GO:0030183 78 0.022
membrane organization GO:0061024 245 0.022
regulation of binding GO:0051098 111 0.022
hemostasis GO:0007599 78 0.022
peptidyl lysine modification GO:0018205 77 0.022
regulation of multi organism process GO:0043900 111 0.022
regulation of inflammatory response GO:0050727 147 0.022
Mouse
epithelial cell proliferation GO:0050673 174 0.022
asymmetric stem cell division GO:0098722 3 0.022
positive regulation of nucleoside metabolic process GO:0045979 91 0.022
digestive system development GO:0055123 200 0.022
regulation of vesicle mediated transport GO:0060627 139 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
mitochondrion organization GO:0007005 134 0.021
regulation of chromosome organization GO:0033044 83 0.021
protein targeting GO:0006605 143 0.021
nuclear transport GO:0051169 139 0.021
regulation of actin filament based process GO:0032970 99 0.021
tube formation GO:0035148 140 0.021
limb development GO:0060173 166 0.021
dendrite development GO:0016358 115 0.021
regulation of metal ion transport GO:0010959 106 0.021
bmp signaling pathway GO:0030509 93 0.021
macromolecule methylation GO:0043414 120 0.021
second messenger mediated signaling GO:0019932 73 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
negative regulation of growth GO:0045926 99 0.021
regulation of cell division GO:0051302 76 0.021
actin polymerization or depolymerization GO:0008154 54 0.021
regulation of hormone levels GO:0010817 211 0.021
stem cell maintenance GO:0019827 130 0.020
calcium ion homeostasis GO:0055074 127 0.020
calcium ion transmembrane transport GO:0070588 85 0.020
negative regulation of synapse assembly GO:0051964 3 0.020
apoptotic signaling pathway GO:0097190 306 0.020
positive regulation of t cell activation GO:0050870 101 0.020
Mouse
striated muscle cell development GO:0055002 125 0.020
cardiac chamber development GO:0003205 108 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
organic anion transport GO:0015711 137 0.020
regulation of cytokine biosynthetic process GO:0042035 59 0.020
cellular response to external stimulus GO:0071496 88 0.020
nucleoside monophosphate metabolic process GO:0009123 85 0.020
regulation of protein catabolic process GO:0042176 108 0.020
mesenchymal cell proliferation GO:0010463 44 0.020
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.020
nucleocytoplasmic transport GO:0006913 139 0.019
response to radiation GO:0009314 165 0.019
organic hydroxy compound biosynthetic process GO:1901617 77 0.019
lipid biosynthetic process GO:0008610 179 0.019
regulation of t cell proliferation GO:0042129 92 0.019
Mouse
negative regulation of immune effector process GO:0002698 55 0.019
cell chemotaxis GO:0060326 81 0.019
myeloid leukocyte differentiation GO:0002573 119 0.019
positive regulation of immune effector process GO:0002699 107 0.019
skeletal muscle fiber development GO:0048741 58 0.019
cellular protein catabolic process GO:0044257 155 0.019
nucleoside monophosphate catabolic process GO:0009125 59 0.019
leukocyte proliferation GO:0070661 172 0.019
Mouse
organelle assembly GO:0070925 177 0.019
response to organic cyclic compound GO:0014070 198 0.019
appendage morphogenesis GO:0035107 149 0.019
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.019
Mouse
single organismal cell cell adhesion GO:0016337 131 0.019
regulation of cytoskeleton organization GO:0051493 122 0.018
intracellular receptor signaling pathway GO:0030522 74 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
establishment of protein localization to organelle GO:0072594 118 0.018
nitrogen compound transport GO:0071705 271 0.018
positive regulation of kinase activity GO:0033674 155 0.018
protein polymerization GO:0051258 57 0.018
erythrocyte differentiation GO:0030218 88 0.018
dorsal ventral axon guidance GO:0033563 3 0.018
appendage development GO:0048736 166 0.018
meiotic nuclear division GO:0007126 115 0.018
muscle fiber development GO:0048747 76 0.018
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
nephron development GO:0072006 109 0.018
response to oxidative stress GO:0006979 123 0.018
protein methylation GO:0006479 81 0.018
positive regulation of innate immune response GO:0045089 80 0.018
Mouse
regulation of ossification GO:0030278 112 0.018
Mouse
organic acid biosynthetic process GO:0016053 86 0.018
positive regulation of growth GO:0045927 104 0.018
glucose homeostasis GO:0042593 128 0.018
neuron death GO:0070997 154 0.018
protein alkylation GO:0008213 81 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
regulation of adaptive immune response GO:0002819 90 0.018
positive regulation of transferase activity GO:0051347 167 0.018
digestive tract development GO:0048565 190 0.018
fatty acid metabolic process GO:0006631 121 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.017
organ growth GO:0035265 117 0.017
pallium development GO:0021543 120 0.017
dna metabolic process GO:0006259 303 0.017
regulation of actin filament length GO:0030832 45 0.017
heart morphogenesis GO:0003007 178 0.017
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
gtp metabolic process GO:0046039 144 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.017
leukocyte chemotaxis GO:0030595 69 0.017
multicellular organismal signaling GO:0035637 91 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
positive regulation of cell adhesion GO:0045785 80 0.017
regulation of protein complex assembly GO:0043254 83 0.017
regulation of nuclear division GO:0051783 56 0.017
i kappab kinase nf kappab signaling GO:0007249 85 0.017
regulation of response to wounding GO:1903034 189 0.017
Mouse
positive regulation of cell cycle GO:0045787 92 0.017
positive regulation of leukocyte proliferation GO:0070665 73 0.017
Mouse
smoothened signaling pathway GO:0007224 105 0.017
stress activated mapk cascade GO:0051403 80 0.017
intestinal epithelial structure maintenance GO:0060729 4 0.017
positive regulation of protein complex assembly GO:0031334 45 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
tissue homeostasis GO:0001894 115 0.017
innate immune response activating signal transduction GO:0002758 50 0.017
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
positive regulation of mitotic cell cycle GO:0045931 41 0.017
protein secretion GO:0009306 111 0.016
Mouse
regulation of b cell activation GO:0050864 81 0.016
t cell differentiation in thymus GO:0033077 77 0.016
regulation of rho protein signal transduction GO:0035023 71 0.016
meiotic cell cycle process GO:1903046 77 0.016
stem cell development GO:0048864 219 0.016
positive regulation of ras gtpase activity GO:0032320 65 0.016
negative regulation of neuron differentiation GO:0045665 101 0.016
rna interference GO:0016246 2 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.016
palate development GO:0060021 76 0.016
positive regulation of ion transport GO:0043270 65 0.016
negative regulation of cell migration GO:0030336 59 0.016
protein import into nucleus GO:0006606 95 0.016
placenta blood vessel development GO:0060674 31 0.016
rhythmic process GO:0048511 174 0.016
atp metabolic process GO:0046034 75 0.016
cell maturation GO:0048469 127 0.016
germ cell development GO:0007281 185 0.016
negative regulation of cell activation GO:0050866 111 0.016
Mouse
protein maturation GO:0051604 176 0.016
negative regulation of neuron apoptotic process GO:0043524 92 0.016
protein import GO:0017038 101 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
gonad development GO:0008406 141 0.016
myeloid leukocyte activation GO:0002274 83 0.016
lipid localization GO:0010876 126 0.016
positive regulation of homeostatic process GO:0032846 64 0.016
spinal cord development GO:0021510 81 0.016
calcium ion transport into cytosol GO:0060402 48 0.016
regulation of transmembrane transport GO:0034762 128 0.016
regulation of actin cytoskeleton organization GO:0032956 84 0.016
mesoderm development GO:0007498 100 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
endocytosis GO:0006897 168 0.015
positive regulation of secretion GO:0051047 130 0.015
Mouse
cellular response to abiotic stimulus GO:0071214 56 0.015
hair follicle development GO:0001942 85 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
lung development GO:0030324 164 0.015
modification dependent protein catabolic process GO:0019941 133 0.015

Icosl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
musculoskeletal system disease DOID:17 0 0.030
disease of metabolism DOID:0014667 0 0.020
nervous system disease DOID:863 0 0.018