Mus musculus

0 known processes

Pla2g6

phospholipase A2, group VI

(Aliases: iPLA2beta,iPLA(2)beta,BB112799,iPLA2)

Pla2g6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic hydroxy compound metabolic process GO:1901615 203 0.100
purine containing compound metabolic process GO:0072521 311 0.098
cellular ketone metabolic process GO:0042180 84 0.089
amine metabolic process GO:0009308 45 0.077
cellular amino acid metabolic process GO:0006520 103 0.074
macromolecule catabolic process GO:0009057 281 0.065
regulation of cellular amine metabolic process GO:0033238 20 0.064
regulation of cellular ketone metabolic process GO:0010565 66 0.059
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
heterocycle catabolic process GO:0046700 280 0.058
aromatic compound catabolic process GO:0019439 286 0.058
organic cyclic compound catabolic process GO:1901361 295 0.057
ribonucleoside triphosphate metabolic process GO:0009199 220 0.055
nucleoside phosphate metabolic process GO:0006753 338 0.054
cellular amine metabolic process GO:0044106 44 0.053
cation transport GO:0006812 399 0.052
Rat
ras protein signal transduction GO:0007265 77 0.051
purine ribonucleoside catabolic process GO:0046130 205 0.049
ribonucleotide metabolic process GO:0009259 291 0.048
nucleotide metabolic process GO:0009117 332 0.048
ribonucleoside metabolic process GO:0009119 245 0.048
alcohol metabolic process GO:0006066 116 0.047
purine nucleotide metabolic process GO:0006163 302 0.047
carbohydrate derivative biosynthetic process GO:1901137 183 0.047
spermatogenesis GO:0007283 284 0.046
organophosphate catabolic process GO:0046434 232 0.046
male gamete generation GO:0048232 285 0.045
acetylcholine transport GO:0015870 2 0.044
response to organonitrogen compound GO:0010243 246 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.043
ribose phosphate metabolic process GO:0019693 291 0.043
cellular lipid metabolic process GO:0044255 323 0.043
Human Rat
glycosyl compound metabolic process GO:1901657 246 0.043
purine ribonucleotide metabolic process GO:0009150 290 0.041
synaptic transmission GO:0007268 329 0.041
Rat
cellular nitrogen compound catabolic process GO:0044270 280 0.041
protein localization to organelle GO:0033365 185 0.041
intracellular protein transport GO:0006886 204 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
purine nucleoside triphosphate metabolic process GO:0009144 226 0.039
organonitrogen compound catabolic process GO:1901565 264 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.038
spermatid differentiation GO:0048515 115 0.037
carbohydrate derivative catabolic process GO:1901136 231 0.037
peptidyl amino acid modification GO:0018193 336 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
purine ribonucleoside metabolic process GO:0046128 241 0.035
protein maturation GO:0051604 176 0.035
cytoplasmic transport GO:0016482 234 0.035
protein modification by small protein conjugation or removal GO:0070647 207 0.035
protein catabolic process GO:0030163 221 0.034
carbohydrate metabolic process GO:0005975 230 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
positive regulation of hydrolase activity GO:0051345 148 0.033
ion transmembrane transport GO:0034220 361 0.033
Rat
purine containing compound catabolic process GO:0072523 213 0.033
positive regulation of protein phosphorylation GO:0001934 242 0.033
Rat
transmembrane transport GO:0055085 412 0.032
Rat
purine nucleoside metabolic process GO:0042278 241 0.032
nucleoside metabolic process GO:0009116 246 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
dna metabolic process GO:0006259 303 0.031
organelle fission GO:0048285 170 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.030
reactive nitrogen species metabolic process GO:2001057 0 0.030
cytokine production GO:0001816 319 0.029
ribonucleoside catabolic process GO:0042454 206 0.029
regulation of neuron differentiation GO:0045664 281 0.029
cellular macromolecule catabolic process GO:0044265 206 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.028
positive regulation of protein modification process GO:0031401 299 0.028
Rat
nitrogen compound transport GO:0071705 271 0.028
Rat
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
acetate ester transport GO:1901374 2 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
nuclear division GO:0000280 158 0.026
purine nucleotide catabolic process GO:0006195 211 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
regulation of cell motility GO:2000145 236 0.026
organelle assembly GO:0070925 177 0.026
cilium morphogenesis GO:0060271 102 0.026
positive regulation of cellular catabolic process GO:0031331 148 0.026
regulation of defense response GO:0031347 233 0.026
oxidation reduction process GO:0055114 342 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
protein processing GO:0016485 163 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
regulation of intracellular transport GO:0032386 159 0.025
regulation of secretion by cell GO:1903530 249 0.025
Rat
regulation of cell projection organization GO:0031344 206 0.025
immune effector process GO:0002252 321 0.025
regulation of kinase activity GO:0043549 249 0.025
regulation of lipoprotein lipase activity GO:0051004 4 0.025
regulation of proteolysis GO:0030162 164 0.024
regulation of organelle organization GO:0033043 289 0.024
Rat
protein targeting GO:0006605 143 0.024
compound eye development GO:0048749 1 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.024
cation homeostasis GO:0055080 212 0.023
Rat
regulation of cellular catabolic process GO:0031329 242 0.023
maintenance of location GO:0051235 89 0.023
microtubule based movement GO:0007018 84 0.023
nucleoside catabolic process GO:0009164 206 0.023
reactive oxygen species biosynthetic process GO:1903409 8 0.022
germ cell development GO:0007281 185 0.022
carbohydrate homeostasis GO:0033500 128 0.022
Rat
establishment of protein localization to organelle GO:0072594 118 0.022
regulation of hydrolase activity GO:0051336 246 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
regulation of secretion GO:0051046 274 0.022
Rat
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
spermatid development GO:0007286 108 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
regulation of transferase activity GO:0051338 263 0.021
protein ubiquitination GO:0016567 171 0.021
mitochondrion organization GO:0007005 134 0.021
Rat
cell adhesion GO:0007155 329 0.021
hormone secretion GO:0046879 128 0.021
Rat
skeletal system development GO:0001501 356 0.021
cholesterol metabolic process GO:0008203 56 0.020
microtubule based process GO:0007017 236 0.020
regulation of membrane potential GO:0042391 192 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
regulation of protein localization GO:0032880 231 0.020
protein localization to membrane GO:0072657 108 0.020
regulation of cytokine production GO:0001817 266 0.020
glycoprotein metabolic process GO:0009100 116 0.020
protein localization to peroxisome GO:0072662 4 0.020
nucleotide catabolic process GO:0009166 217 0.020
reactive oxygen species metabolic process GO:0072593 84 0.019
cellular homeostasis GO:0019725 240 0.019
Rat
protein glycosylation GO:0006486 55 0.019
cellular protein catabolic process GO:0044257 155 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
glycerolipid metabolic process GO:0046486 122 0.019
Human
locomotory behavior GO:0007626 195 0.019
sensory perception GO:0007600 245 0.019
chemotaxis GO:0006935 247 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
positive regulation of transferase activity GO:0051347 167 0.018
regulation of protein transport GO:0051223 163 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
regulation of cell migration GO:0030334 219 0.018
regulation of nucleoside metabolic process GO:0009118 130 0.018
positive regulation of apoptotic process GO:0043065 217 0.017
Rat
rho protein signal transduction GO:0007266 32 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
Rat
nuclear transport GO:0051169 139 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
leukocyte differentiation GO:0002521 342 0.017
protein targeting to peroxisome GO:0006625 4 0.017
sterol metabolic process GO:0016125 58 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
apoptotic signaling pathway GO:0097190 306 0.017
Rat
anion transport GO:0006820 177 0.017
Rat
negative regulation of protein modification process GO:0031400 163 0.017
regulation of protein kinase activity GO:0045859 232 0.017
small molecule catabolic process GO:0044282 71 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
camera type eye development GO:0043010 266 0.017
organic anion transport GO:0015711 137 0.017
Rat
response to radiation GO:0009314 165 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.017
negative regulation of molecular function GO:0044092 258 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.016
lipid transport GO:0006869 98 0.016
Rat
anion transmembrane transport GO:0098656 71 0.016
steroid metabolic process GO:0008202 119 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
actin cytoskeleton organization GO:0030036 220 0.016
cellular response to peptide GO:1901653 92 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
response to peptide hormone GO:0043434 127 0.016
sequestering of calcium ion GO:0051208 18 0.016
leukocyte migration GO:0050900 124 0.016
cation transmembrane transport GO:0098655 266 0.016
Rat
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.016
glycosylation GO:0070085 62 0.015
organic acid transport GO:0015849 101 0.015
Rat
dna repair GO:0006281 107 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
regulation of homeostatic process GO:0032844 182 0.015
Rat
asymmetric stem cell division GO:0098722 3 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
membrane organization GO:0061024 245 0.015
meiotic cell cycle GO:0051321 122 0.015
bone development GO:0060348 120 0.015
regulation of cell cycle GO:0051726 281 0.015
regulation of cell adhesion GO:0030155 154 0.015
chromatin organization GO:0006325 206 0.015
gtp metabolic process GO:0046039 144 0.015
peptide secretion GO:0002790 114 0.015
Rat
small gtpase mediated signal transduction GO:0007264 97 0.015
chromatin modification GO:0016568 187 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
regulation of hormone levels GO:0010817 211 0.014
Rat
glycerophospholipid metabolic process GO:0006650 71 0.014
Human
multicellular organismal signaling GO:0035637 91 0.014
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.014
gtp catabolic process GO:0006184 143 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
Rat
renal system development GO:0072001 225 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
Rat
carboxylic acid transport GO:0046942 100 0.014
Rat
cellular response to lipopolysaccharide GO:0071222 77 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
ossification GO:0001503 216 0.014
calcium ion homeostasis GO:0055074 127 0.014
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
response to lipopolysaccharide GO:0032496 128 0.014
regulation of cellular response to stress GO:0080135 159 0.014
asymmetric neuroblast division GO:0055059 1 0.014
forebrain development GO:0030900 302 0.014
response to light stimulus GO:0009416 135 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
positive regulation of kinase activity GO:0033674 155 0.014
metal ion homeostasis GO:0055065 189 0.014
Rat
positive regulation of triglyceride lipase activity GO:0061365 3 0.014
multicellular organism growth GO:0035264 161 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
positive regulation of cell migration GO:0030335 109 0.013
exocytosis GO:0006887 121 0.013
Rat
insulin secretion GO:0030073 89 0.013
Rat
cell growth GO:0016049 130 0.013
atp metabolic process GO:0046034 75 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
response to nutrient levels GO:0031667 109 0.013
ameboidal type cell migration GO:0001667 128 0.013
muscle tissue development GO:0060537 308 0.013
response to peptide GO:1901652 136 0.013
histone modification GO:0016570 159 0.013
endocytosis GO:0006897 168 0.013
regulation of cholesterol metabolic process GO:0090181 14 0.013
positive regulation of cell development GO:0010720 237 0.013
t cell activation GO:0042110 289 0.013
positive regulation of cell death GO:0010942 224 0.013
Rat
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
endomembrane system organization GO:0010256 147 0.013
regulation of protein targeting GO:1903533 61 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
regulation of ral gtpase activity GO:0032315 4 0.013
negative regulation of cell development GO:0010721 169 0.013
regulation of gtp catabolic process GO:0033124 113 0.013
connective tissue development GO:0061448 179 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
neuron death GO:0070997 154 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
Rat
regulation of binding GO:0051098 111 0.013
response to oxidative stress GO:0006979 123 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
respiratory tube development GO:0030323 167 0.012
meiotic nuclear division GO:0007126 115 0.012
macromolecule glycosylation GO:0043413 55 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
lateral inhibition GO:0046331 1 0.012
fatty acid metabolic process GO:0006631 121 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
skeletal system morphogenesis GO:0048705 203 0.012
response to temperature stimulus GO:0009266 55 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
Rat
cellular response to growth factor stimulus GO:0071363 197 0.012
response to growth factor GO:0070848 198 0.012
response to extracellular stimulus GO:0009991 127 0.012
small molecule biosynthetic process GO:0044283 132 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
Rat
sensory organ morphogenesis GO:0090596 242 0.012
mapk cascade GO:0000165 281 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
organic acid catabolic process GO:0016054 51 0.012
regulation of protein catabolic process GO:0042176 108 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
Rat
inorganic ion transmembrane transport GO:0098660 234 0.012
Rat
cellular response to cytokine stimulus GO:0071345 189 0.012
lipid localization GO:0010876 126 0.012
Rat
telencephalon development GO:0021537 186 0.012
triglyceride metabolic process GO:0006641 51 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
mitotic cell cycle GO:0000278 195 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
response to endoplasmic reticulum stress GO:0034976 53 0.012
Rat
anatomical structure homeostasis GO:0060249 145 0.011
learning GO:0007612 98 0.011
response to insulin GO:0032868 100 0.011
cell substrate adhesion GO:0031589 130 0.011
mrna metabolic process GO:0016071 84 0.011
sequestering of metal ion GO:0051238 19 0.011
regulation of system process GO:0044057 200 0.011
Rat
muscle system process GO:0003012 141 0.011
Rat
learning or memory GO:0007611 148 0.011
Rat
covalent chromatin modification GO:0016569 163 0.011
cellular protein complex assembly GO:0043623 116 0.011
fat cell differentiation GO:0045444 160 0.011
negative regulation of nervous system development GO:0051961 156 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
energy derivation by oxidation of organic compounds GO:0015980 77 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
extracellular matrix organization GO:0030198 147 0.011
sensory system development GO:0048880 3 0.011
carboxylic acid catabolic process GO:0046395 51 0.011
regulation of mapk cascade GO:0043408 248 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
oocyte axis specification GO:0007309 2 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
Rat
regulation of lymphocyte activation GO:0051249 240 0.011
smoothened signaling pathway GO:0007224 105 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
neutral lipid metabolic process GO:0006638 57 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
response to starvation GO:0042594 65 0.011
regulation of neuron death GO:1901214 134 0.011
response to inorganic substance GO:0010035 96 0.011
axonogenesis GO:0007409 274 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
peptide hormone secretion GO:0030072 109 0.011
Rat
negative regulation of growth GO:0045926 99 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
negative regulation of proteolysis GO:0045861 74 0.011
rna processing GO:0006396 105 0.011
regulation of cell cycle process GO:0010564 160 0.011
establishment of protein localization to peroxisome GO:0072663 4 0.011
action potential GO:0001508 78 0.011
protein import GO:0017038 101 0.011
positive regulation of ras gtpase activity GO:0032320 65 0.011
negative regulation of dna replication GO:0008156 4 0.010
peptide transport GO:0015833 133 0.010
Rat
extracellular structure organization GO:0043062 148 0.010
interleukin 8 production GO:0032637 4 0.010
rhythmic process GO:0048511 174 0.010
amide transport GO:0042886 138 0.010
Rat
positive regulation of cell projection organization GO:0031346 95 0.010
positive regulation of lipoprotein lipase activity GO:0051006 3 0.010
positive regulation of intracellular transport GO:0032388 70 0.010
positive regulation of organelle organization GO:0010638 128 0.010
Rat
transmission of nerve impulse GO:0019226 76 0.010
glycerolipid biosynthetic process GO:0045017 50 0.010
Human
negative regulation of synapse assembly GO:0051964 3 0.010
retina morphogenesis in camera type eye GO:0060042 45 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
inflammatory response GO:0006954 244 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
methylation GO:0032259 134 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
fertilization GO:0009566 127 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
ral protein signal transduction GO:0032484 2 0.010
protein autophosphorylation GO:0046777 61 0.010

Pla2g6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
Human
nervous system disease DOID:863 0 0.034
Human
disease of cellular proliferation DOID:14566 0 0.026
cancer DOID:162 0 0.025
organ system cancer DOID:0050686 0 0.025
central nervous system disease DOID:331 0 0.020
Human
brain disease DOID:936 0 0.020
immune system disease DOID:2914 0 0.019
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.012