Mus musculus

0 known processes

Nup98

nucleoporin 98

(Aliases: MGC118567,Nup96,4732457F17,AI849286)

Nup98 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.115
cellular ketone metabolic process GO:0042180 84 0.100
regulation of organelle organization GO:0033043 289 0.088
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.086
mitotic cell cycle GO:0000278 195 0.079
protein modification by small protein conjugation or removal GO:0070647 207 0.069
regulation of chromosome organization GO:0033044 83 0.069
cellular macromolecule catabolic process GO:0044265 206 0.067
peptidyl amino acid modification GO:0018193 336 0.064
chromatin organization GO:0006325 206 0.059
positive regulation of cell death GO:0010942 224 0.058
macromolecule catabolic process GO:0009057 281 0.056
stem cell differentiation GO:0048863 268 0.055
amine metabolic process GO:0009308 45 0.055
regulation of cell cycle GO:0051726 281 0.055
negative regulation of cellular protein metabolic process GO:0032269 247 0.052
intracellular protein transport GO:0006886 204 0.050
chromatin modification GO:0016568 187 0.049
regulation of inflammatory response GO:0050727 147 0.048
regulation of response to wounding GO:1903034 189 0.047
positive regulation of apoptotic process GO:0043065 217 0.046
development of primary sexual characteristics GO:0045137 143 0.046
Worm
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.045
regulation of cellular ketone metabolic process GO:0010565 66 0.044
cellular amine metabolic process GO:0044106 44 0.042
rna processing GO:0006396 105 0.042
gonad development GO:0008406 141 0.042
Worm
positive regulation of programmed cell death GO:0043068 218 0.040
apoptotic signaling pathway GO:0097190 306 0.039
spermatogenesis GO:0007283 284 0.039
posttranscriptional regulation of gene expression GO:0010608 155 0.039
nitrogen compound transport GO:0071705 271 0.039
histone modification GO:0016570 159 0.038
cellular response to hormone stimulus GO:0032870 150 0.037
modification dependent macromolecule catabolic process GO:0043632 133 0.037
protein ubiquitination GO:0016567 171 0.037
cellular response to organonitrogen compound GO:0071417 145 0.037
inflammatory response GO:0006954 244 0.037
male gamete generation GO:0048232 285 0.036
negative regulation of protein metabolic process GO:0051248 282 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
response to growth factor GO:0070848 198 0.036
regulation of cell cycle process GO:0010564 160 0.035
ribose phosphate metabolic process GO:0019693 291 0.035
stem cell maintenance GO:0019827 130 0.035
stem cell development GO:0048864 219 0.035
positive regulation of lymphocyte activation GO:0051251 140 0.034
negative regulation of cell proliferation GO:0008285 296 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
negative regulation of intracellular signal transduction GO:1902532 167 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
cellular response to growth factor stimulus GO:0071363 197 0.032
regulation of cell activation GO:0050865 289 0.032
aromatic compound catabolic process GO:0019439 286 0.032
cell adhesion GO:0007155 329 0.031
skeletal system development GO:0001501 356 0.031
protein localization to nucleus GO:0034504 121 0.031
nucleocytoplasmic transport GO:0006913 139 0.031
positive regulation of hydrolase activity GO:0051345 148 0.030
protein catabolic process GO:0030163 221 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.030
gland development GO:0048732 330 0.029
germ cell development GO:0007281 185 0.029
Worm
regulation of membrane potential GO:0042391 192 0.029
organelle fission GO:0048285 170 0.029
mitotic cell cycle process GO:1903047 159 0.029
regulation of intracellular transport GO:0032386 159 0.028
cellular lipid metabolic process GO:0044255 323 0.028
action potential GO:0001508 78 0.028
positive regulation of t cell activation GO:0050870 101 0.027
oocyte axis specification GO:0007309 2 0.027
Worm
regulation of hydrolase activity GO:0051336 246 0.027
compound eye development GO:0048749 1 0.027
membrane organization GO:0061024 245 0.027
protein import into nucleus GO:0006606 95 0.026
response to oxidative stress GO:0006979 123 0.026
regulation of lymphocyte activation GO:0051249 240 0.026
protein localization to organelle GO:0033365 185 0.026
regulation of nucleotide metabolic process GO:0006140 169 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
positive regulation of protein modification process GO:0031401 299 0.026
response to peptide GO:1901652 136 0.026
protein acylation GO:0043543 64 0.026
negative regulation of protein modification process GO:0031400 163 0.026
negative regulation of molecular function GO:0044092 258 0.026
protein import GO:0017038 101 0.026
regulation of proteolysis GO:0030162 164 0.026
sulfur compound metabolic process GO:0006790 100 0.026
regulation of leukocyte mediated immunity GO:0002703 104 0.025
rhythmic process GO:0048511 174 0.025
negative regulation of nervous system development GO:0051961 156 0.025
sensory organ morphogenesis GO:0090596 242 0.025
protein maturation GO:0051604 176 0.025
b cell activation GO:0042113 161 0.025
t cell activation GO:0042110 289 0.024
lymphocyte mediated immunity GO:0002449 139 0.024
modification dependent protein catabolic process GO:0019941 133 0.024
immunoglobulin production GO:0002377 73 0.024
response to organonitrogen compound GO:0010243 246 0.024
methylation GO:0032259 134 0.024
protein alkylation GO:0008213 81 0.024
multicellular organismal signaling GO:0035637 91 0.024
negative regulation of cell development GO:0010721 169 0.024
transmission of nerve impulse GO:0019226 76 0.023
mrna metabolic process GO:0016071 84 0.023
intrinsic apoptotic signaling pathway GO:0097193 132 0.023
regulation of chromatin organization GO:1902275 57 0.023
urogenital system development GO:0001655 261 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
embryonic epithelial tube formation GO:0001838 130 0.023
covalent chromatin modification GO:0016569 163 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
cytokine mediated signaling pathway GO:0019221 115 0.023
microtubule based process GO:0007017 236 0.023
i kappab kinase nf kappab signaling GO:0007249 85 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
ossification GO:0001503 216 0.022
response to peptide hormone GO:0043434 127 0.022
macromolecule methylation GO:0043414 120 0.022
transmembrane transport GO:0055085 412 0.022
regulation of defense response GO:0031347 233 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
cellular response to peptide hormone stimulus GO:0071375 92 0.022
respiratory system development GO:0060541 190 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
protein targeting GO:0006605 143 0.021
multicellular organismal homeostasis GO:0048871 164 0.021
blood vessel morphogenesis GO:0048514 285 0.021
regulation of transferase activity GO:0051338 263 0.021
dna metabolic process GO:0006259 303 0.021
Human
leukocyte mediated immunity GO:0002443 174 0.021
spermatid development GO:0007286 108 0.021
multicellular organism growth GO:0035264 161 0.021
regulation of homeostatic process GO:0032844 182 0.021
protein methylation GO:0006479 81 0.021
renal system development GO:0072001 225 0.021
histone acetylation GO:0016573 41 0.021
nucleotide metabolic process GO:0009117 332 0.021
regulation of histone modification GO:0031056 56 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
nuclear transport GO:0051169 139 0.020
histone methylation GO:0016571 71 0.020
nuclear division GO:0000280 158 0.020
regulation of system process GO:0044057 200 0.020
leukocyte differentiation GO:0002521 342 0.020
cell activation involved in immune response GO:0002263 126 0.020
regulation of t cell activation GO:0050863 170 0.020
nucleus organization GO:0006997 45 0.020
Human Worm
cellular response to lipid GO:0071396 145 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
fatty acid metabolic process GO:0006631 121 0.020
morphogenesis of a branching epithelium GO:0061138 193 0.020
spermatid differentiation GO:0048515 115 0.020
peptidyl lysine modification GO:0018205 77 0.020
immune effector process GO:0002252 321 0.020
regulation of mapk cascade GO:0043408 248 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
myeloid cell differentiation GO:0030099 233 0.019
connective tissue development GO:0061448 179 0.019
nucleoside metabolic process GO:0009116 246 0.019
response to lipopolysaccharide GO:0032496 128 0.019
regulation of cellular response to stress GO:0080135 159 0.019
regulation of kinase activity GO:0043549 249 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
ras protein signal transduction GO:0007265 77 0.019
cation transmembrane transport GO:0098655 266 0.019
fat cell differentiation GO:0045444 160 0.019
respiratory tube development GO:0030323 167 0.018
regulation of protein localization GO:0032880 231 0.018
b cell differentiation GO:0030183 78 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
histone lysine methylation GO:0034968 50 0.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
t cell differentiation GO:0030217 174 0.018
cation transport GO:0006812 399 0.018
defense response to other organism GO:0098542 197 0.018
regulation of protein stability GO:0031647 52 0.018
regulation of cell adhesion GO:0030155 154 0.018
cytoplasmic transport GO:0016482 234 0.018
lymphocyte differentiation GO:0030098 242 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
cell maturation GO:0048469 127 0.018
Worm
leukocyte activation involved in immune response GO:0002366 126 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
cellular response to oxidative stress GO:0034599 76 0.017
regulation of hormone levels GO:0010817 211 0.017
purine containing compound metabolic process GO:0072521 311 0.017
regulation of lymphocyte mediated immunity GO:0002706 84 0.017
nuclear import GO:0051170 95 0.017
adaptive immune response GO:0002250 155 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
positive regulation of cell cycle GO:0045787 92 0.017
glucose homeostasis GO:0042593 128 0.017
production of molecular mediator of immune response GO:0002440 103 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
regulation of cytokine production GO:0001817 266 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
locomotory behavior GO:0007626 195 0.017
gliogenesis GO:0042063 141 0.017
regulation of adaptive immune response GO:0002819 90 0.017
homeostasis of number of cells GO:0048872 210 0.017
negative regulation of immune system process GO:0002683 209 0.017
cell type specific apoptotic process GO:0097285 268 0.016
regionalization GO:0003002 337 0.016
Worm
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
meiotic cell cycle GO:0051321 122 0.016
t cell proliferation GO:0042098 120 0.016
maintenance of location GO:0051235 89 0.016
mrna processing GO:0006397 63 0.016
developmental maturation GO:0021700 193 0.016
Worm
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
response to inorganic substance GO:0010035 96 0.016
alpha amino acid metabolic process GO:1901605 59 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
purine containing compound catabolic process GO:0072523 213 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
somatic cell dna recombination GO:0016444 51 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
regulation of neuron differentiation GO:0045664 281 0.016
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.016
camera type eye development GO:0043010 266 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
cellular protein catabolic process GO:0044257 155 0.015
lipid localization GO:0010876 126 0.015
ion transmembrane transport GO:0034220 361 0.015
positive regulation of leukocyte mediated immunity GO:0002705 70 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
dna recombination GO:0006310 92 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
cellular response to peptide GO:1901653 92 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
organelle assembly GO:0070925 177 0.015
regulation of binding GO:0051098 111 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
regulation of chromatin modification GO:1903308 57 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
carbohydrate homeostasis GO:0033500 128 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
alpha beta t cell activation GO:0046631 91 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
mapk cascade GO:0000165 281 0.015
regulation of protein kinase activity GO:0045859 232 0.015
regulation of cell migration GO:0030334 219 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
rna localization GO:0006403 23 0.015
response to radiation GO:0009314 165 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
positive regulation of leukocyte differentiation GO:1902107 86 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
regulation of secretion by cell GO:1903530 249 0.014
single organism nuclear import GO:1902593 95 0.014
cytokine production GO:0001816 319 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
regulation of t cell proliferation GO:0042129 92 0.014
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
regulation of immunoglobulin production GO:0002637 42 0.014
innate immune response GO:0045087 157 0.014
regulation of protein transport GO:0051223 163 0.014
axonogenesis GO:0007409 274 0.014
rna splicing GO:0008380 54 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
regulation of cell motility GO:2000145 236 0.014
nucleobase containing compound transport GO:0015931 27 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
cellular amide metabolic process GO:0043603 58 0.014
neuronal action potential GO:0019228 54 0.014
positive regulation of lymphocyte differentiation GO:0045621 61 0.014
skeletal system morphogenesis GO:0048705 203 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.014
negative regulation of chromosome organization GO:2001251 30 0.014
angiogenesis GO:0001525 201 0.013
regulation of production of molecular mediator of immune response GO:0002700 65 0.013
positive regulation of adaptive immune response GO:0002821 61 0.013
negative regulation of organelle organization GO:0010639 90 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
cardiac muscle cell contraction GO:0086003 7 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
peptidyl lysine acetylation GO:0018394 45 0.013
meiotic nuclear division GO:0007126 115 0.013
carbohydrate metabolic process GO:0005975 230 0.013
sequestering of calcium ion GO:0051208 18 0.013
natural killer cell activation GO:0030101 44 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
response to insulin GO:0032868 100 0.013
adult behavior GO:0030534 135 0.013
nucleotide catabolic process GO:0009166 217 0.013
negative regulation of cell activation GO:0050866 111 0.013
neural tube development GO:0021915 160 0.013
response to organic cyclic compound GO:0014070 198 0.013
leukocyte apoptotic process GO:0071887 71 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
lung development GO:0030324 164 0.012
lipid biosynthetic process GO:0008610 179 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
blastocyst development GO:0001824 80 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
regulation of carbohydrate metabolic process GO:0006109 75 0.012
tube formation GO:0035148 140 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
response to acid chemical GO:0001101 111 0.012
somatic diversification of immunoglobulins GO:0016445 43 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
regulation of response to dna damage stimulus GO:2001020 34 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
positive regulation of t cell differentiation GO:0045582 52 0.012
regulation of body fluid levels GO:0050878 162 0.012
regulation of histone methylation GO:0031060 30 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
muscle cell differentiation GO:0042692 261 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
cellular homeostasis GO:0019725 240 0.012
positive regulation of b cell activation GO:0050871 49 0.012
regulation of protein complex assembly GO:0043254 83 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
positive regulation of growth GO:0045927 104 0.012
alpha beta t cell differentiation GO:0046632 69 0.012
response to light stimulus GO:0009416 135 0.012
cellular modified amino acid metabolic process GO:0006575 63 0.012
regulation of secretion GO:0051046 274 0.012
organophosphate catabolic process GO:0046434 232 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
digestive system development GO:0055123 200 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
circulatory system process GO:0003013 197 0.012
negative regulation of inflammatory response GO:0050728 61 0.012
jak stat cascade GO:0007259 42 0.012
male sex differentiation GO:0046661 109 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
epithelial tube formation GO:0072175 130 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
regulation of dna recombination GO:0000018 34 0.012
actin mediated cell contraction GO:0070252 15 0.012
engulfment of apoptotic cell GO:0043652 3 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
regulation of t cell differentiation GO:0045580 83 0.011
cellular protein complex assembly GO:0043623 116 0.011
Human
purine nucleoside metabolic process GO:0042278 241 0.011
lymphocyte proliferation GO:0046651 164 0.011
positive regulation of nervous system development GO:0051962 221 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
gene silencing by rna GO:0031047 19 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
anatomical structure homeostasis GO:0060249 145 0.011
oxidation reduction process GO:0055114 342 0.011
intracellular receptor signaling pathway GO:0030522 74 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
activation of immune response GO:0002253 138 0.011
learning or memory GO:0007611 148 0.011
somatic sex determination GO:0018993 2 0.011
negative regulation of defense response GO:0031348 77 0.011
cellular response to acid chemical GO:0071229 68 0.011
oocyte construction GO:0007308 2 0.011
Worm
blood circulation GO:0008015 195 0.011
rna splicing via transesterification reactions GO:0000375 43 0.011
regulation of protein catabolic process GO:0042176 108 0.011
female gamete generation GO:0007292 74 0.011
Worm
internal protein amino acid acetylation GO:0006475 42 0.011
forebrain development GO:0030900 302 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
signal transduction by p53 class mediator GO:0072331 51 0.011
natural killer cell proliferation GO:0001787 3 0.010
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
regulation of cytoskeleton organization GO:0051493 122 0.010
ncrna processing GO:0034470 26 0.010
mrna splicing via spliceosome GO:0000398 43 0.010
axon ensheathment GO:0008366 76 0.010
multi multicellular organism process GO:0044706 109 0.010
regulation of lymphocyte proliferation GO:0050670 117 0.010
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.010
internal peptidyl lysine acetylation GO:0018393 42 0.010
circadian rhythm GO:0007623 114 0.010
organic anion transport GO:0015711 137 0.010
positive regulation of nucleoside metabolic process GO:0045979 91 0.010
tube closure GO:0060606 91 0.010
positive regulation of cell activation GO:0050867 158 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
positive regulation of proteolysis GO:0045862 85 0.010
protein processing GO:0016485 163 0.010
cognition GO:0050890 149 0.010
cell division GO:0051301 120 0.010
cartilage development GO:0051216 140 0.010
epithelial cell development GO:0002064 159 0.010

Nup98 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.039
disease of anatomical entity DOID:7 0 0.039
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
central nervous system disease DOID:331 0 0.013