Mus musculus

91 known processes

Tmed2

transmembrane emp24 domain trafficking protein 2

(Aliases: p24beta1,Sid394,MGC102446,1110032D12Rik,1810020N21Rik,Rnp24)

Tmed2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoplasmic transport GO:0016482 234 0.178
Yeast Worm
membrane organization GO:0061024 245 0.170
Human
regulation of protein localization GO:0032880 231 0.087
leukocyte differentiation GO:0002521 342 0.087
skeletal system development GO:0001501 356 0.085
cellular amino acid metabolic process GO:0006520 103 0.082
regulation of secretion by cell GO:1903530 249 0.078
ribonucleotide metabolic process GO:0009259 291 0.075
Human
peptidyl amino acid modification GO:0018193 336 0.074
regulation of apoptotic signaling pathway GO:2001233 197 0.065
apoptotic signaling pathway GO:0097190 306 0.062
carbohydrate derivative biosynthetic process GO:1901137 183 0.062
localization within membrane GO:0051668 4 0.061
amine metabolic process GO:0009308 45 0.061
purine ribonucleotide metabolic process GO:0009150 290 0.059
Human
positive regulation of protein modification process GO:0031401 299 0.057
intracellular protein transport GO:0006886 204 0.055
Human
purine containing compound metabolic process GO:0072521 311 0.055
Human
regulation of secretion GO:0051046 274 0.055
positive regulation of secretion by cell GO:1903532 114 0.054
cation homeostasis GO:0055080 212 0.051
endomembrane system organization GO:0010256 147 0.050
Human
carbohydrate metabolic process GO:0005975 230 0.050
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
nitrogen compound transport GO:0071705 271 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.045
cellular homeostasis GO:0019725 240 0.045
cellular amine metabolic process GO:0044106 44 0.044
er nucleus signaling pathway GO:0006984 27 0.044
regulation of hormone levels GO:0010817 211 0.042
intra golgi vesicle mediated transport GO:0006891 1 0.042
establishment of vesicle localization GO:0051650 81 0.040
multi multicellular organism process GO:0044706 109 0.040
organelle localization GO:0051640 179 0.040
response to topologically incorrect protein GO:0035966 25 0.038
macromolecule glycosylation GO:0043413 55 0.037
aromatic compound catabolic process GO:0019439 286 0.037
Human
response to organonitrogen compound GO:0010243 246 0.037
purine nucleoside triphosphate metabolic process GO:0009144 226 0.037
Human
regulation of establishment of protein localization GO:0070201 181 0.036
oxidation reduction process GO:0055114 342 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.035
glycoprotein biosynthetic process GO:0009101 89 0.035
endocytosis GO:0006897 168 0.035
regulation of protein exit from endoplasmic reticulum GO:0070861 1 0.035
establishment of organelle localization GO:0051656 122 0.035
regulation of cellular component biogenesis GO:0044087 181 0.034
response to organic cyclic compound GO:0014070 198 0.034
response to unfolded protein GO:0006986 21 0.034
male gamete generation GO:0048232 285 0.034
positive regulation of growth GO:0045927 104 0.033
regulation of leukocyte differentiation GO:1902105 159 0.033
nucleoside catabolic process GO:0009164 206 0.033
Human
positive regulation of protein phosphorylation GO:0001934 242 0.033
regionalization GO:0003002 337 0.033
lymphocyte differentiation GO:0030098 242 0.032
nucleoside metabolic process GO:0009116 246 0.032
Human
positive regulation of kinase activity GO:0033674 155 0.030
regulation of cell activation GO:0050865 289 0.030
gland development GO:0048732 330 0.030
cellular response to antibiotic GO:0071236 4 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.029
Human
inorganic ion transmembrane transport GO:0098660 234 0.029
male sex differentiation GO:0046661 109 0.029
regulation of intracellular transport GO:0032386 159 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
regulation of lymphocyte activation GO:0051249 240 0.029
regulation of organelle organization GO:0033043 289 0.029
cellular ketone metabolic process GO:0042180 84 0.029
glycoprotein metabolic process GO:0009100 116 0.028
extrinsic apoptotic signaling pathway GO:0097191 126 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
Human
regulation of cell migration GO:0030334 219 0.027
regulation of vesicle mediated transport GO:0060627 139 0.027
camera type eye development GO:0043010 266 0.026
circulatory system process GO:0003013 197 0.026
immune effector process GO:0002252 321 0.025
myeloid cell differentiation GO:0030099 233 0.025
regulation of mapk cascade GO:0043408 248 0.025
regulation of lymphocyte differentiation GO:0045619 107 0.024
digestive tract development GO:0048565 190 0.024
regulation of intracellular protein transport GO:0033157 82 0.024
placenta development GO:0001890 140 0.024
spermatogenesis GO:0007283 284 0.023
regulation of kinase activity GO:0043549 249 0.023
cell adhesion GO:0007155 329 0.023
forebrain development GO:0030900 302 0.023
muscle cell differentiation GO:0042692 261 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
Human
amide transport GO:0042886 138 0.023
4 hydroxyproline metabolic process GO:0019471 5 0.023
heterocycle catabolic process GO:0046700 280 0.023
Human
cellular response to biotic stimulus GO:0071216 92 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
Human
negative regulation of cellular component organization GO:0051129 194 0.022
negative regulation of molecular function GO:0044092 258 0.022
Human
regulation of protein kinase activity GO:0045859 232 0.022
transmembrane transport GO:0055085 412 0.022
regulation of protein transport GO:0051223 163 0.022
positive regulation of protein kinase activity GO:0045860 144 0.022
regulation of hydrolase activity GO:0051336 246 0.022
Human
nucleotide metabolic process GO:0009117 332 0.021
Human
regulation of cellular ketone metabolic process GO:0010565 66 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
cation transport GO:0006812 399 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
cation transmembrane transport GO:0098655 266 0.021
response to growth factor GO:0070848 198 0.021
t cell activation GO:0042110 289 0.020
lateral inhibition GO:0046331 1 0.020
protein targeting GO:0006605 143 0.020
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
Human
regulation of cell motility GO:2000145 236 0.020
cellular chemical homeostasis GO:0055082 215 0.020
synaptic transmission GO:0007268 329 0.020
ubiquitin dependent protein catabolic process GO:0006511 129 0.020
ribonucleotide biosynthetic process GO:0009260 59 0.019
proteasomal protein catabolic process GO:0010498 98 0.019
inter male aggressive behavior GO:0002121 3 0.019
cellular response to lipid GO:0071396 145 0.019
chromatin organization GO:0006325 206 0.019
maintenance of location GO:0051235 89 0.019
Yeast
establishment of protein localization to organelle GO:0072594 118 0.019
positive regulation of secretion GO:0051047 130 0.019
bone development GO:0060348 120 0.019
multicellular organismal signaling GO:0035637 91 0.019
lymphocyte mediated immunity GO:0002449 139 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
Human
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
regulation of er to golgi vesicle mediated transport GO:0060628 4 0.018
skeletal system morphogenesis GO:0048705 203 0.018
calcium ion homeostasis GO:0055074 127 0.018
protein exit from endoplasmic reticulum GO:0032527 1 0.018
epithelial cell proliferation GO:0050673 174 0.018
ion transmembrane transport GO:0034220 361 0.018
hormone secretion GO:0046879 128 0.018
positive regulation of cell motility GO:2000147 116 0.018
nucleocytoplasmic transport GO:0006913 139 0.017
development of primary male sexual characteristics GO:0046546 88 0.017
t cell differentiation GO:0030217 174 0.017
cellular ion homeostasis GO:0006873 165 0.017
golgi vesicle transport GO:0048193 30 0.017
Yeast Worm
asymmetric stem cell division GO:0098722 3 0.017
positive regulation of phospholipase activity GO:0010518 3 0.017
muscle tissue development GO:0060537 308 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
Human
regulation of actin filament based process GO:0032970 99 0.017
histone modification GO:0016570 159 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
spermatid development GO:0007286 108 0.017
cellular lipid metabolic process GO:0044255 323 0.017
cartilage development GO:0051216 140 0.016
negative regulation of cell activation GO:0050866 111 0.016
regulation of t cell differentiation GO:0045580 83 0.016
connective tissue development GO:0061448 179 0.016
regulation of vacuole organization GO:0044088 4 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
Human
positive regulation of mapk cascade GO:0043410 170 0.016
response to oxygen radical GO:0000305 16 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
Human
nucleoside phosphate metabolic process GO:0006753 338 0.016
Human
endoplasmic reticulum unfolded protein response GO:0030968 19 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
substantia nigra development GO:0021762 2 0.016
male gonad development GO:0008584 88 0.016
regulation of multi organism process GO:0043900 111 0.016
multicellular organism growth GO:0035264 161 0.016
actin polymerization or depolymerization GO:0008154 54 0.016
compound eye development GO:0048749 1 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
Human
macromolecule catabolic process GO:0009057 281 0.015
multi organism reproductive behavior GO:0044705 29 0.015
extracellular structure organization GO:0043062 148 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
Human
regulation of protein complex assembly GO:0043254 83 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
cytokine production GO:0001816 319 0.015
positive regulation of cell death GO:0010942 224 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
protein maturation GO:0051604 176 0.015
methylation GO:0032259 134 0.015
regulation of cytokine production GO:0001817 266 0.015
sensory perception GO:0007600 245 0.015
action potential GO:0001508 78 0.015
regulation of anatomical structure size GO:0090066 178 0.015
cellular response to external stimulus GO:0071496 88 0.015
establishment of protein localization to membrane GO:0090150 54 0.015
Human
purine containing compound biosynthetic process GO:0072522 70 0.015
epithelial cell development GO:0002064 159 0.015
vacuole organization GO:0007033 38 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
Human
striated muscle tissue development GO:0014706 293 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
ras protein signal transduction GO:0007265 77 0.014
peptide hormone secretion GO:0030072 109 0.014
nucleotide biosynthetic process GO:0009165 78 0.014
multi organism behavior GO:0051705 62 0.014
b cell activation GO:0042113 161 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
lung development GO:0030324 164 0.014
protein folding GO:0006457 28 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
protein localization to membrane GO:0072657 108 0.014
Human
divalent inorganic cation transport GO:0072511 178 0.014
glucose metabolic process GO:0006006 92 0.014
digestive system development GO:0055123 200 0.014
regulation of t cell activation GO:0050863 170 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
Human
myeloid leukocyte differentiation GO:0002573 119 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
extracellular matrix organization GO:0030198 147 0.014
anatomical structure homeostasis GO:0060249 145 0.014
regulation of protein stability GO:0031647 52 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
cellular protein complex assembly GO:0043623 116 0.013
regulation of response to wounding GO:1903034 189 0.013
mapk cascade GO:0000165 281 0.013
receptor mediated endocytosis GO:0006898 51 0.013
protein acylation GO:0043543 64 0.013
golgi organization GO:0007030 9 0.013
Human
chromatin modification GO:0016568 187 0.013
spermatid differentiation GO:0048515 115 0.013
peptide transport GO:0015833 133 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
Human
response to molecule of bacterial origin GO:0002237 143 0.013
mitotic cytokinesis GO:0000281 4 0.013
response to lipopolysaccharide GO:0032496 128 0.013
regulation of reproductive process GO:2000241 66 0.013
wnt signaling pathway GO:0016055 188 0.013
cell aging GO:0007569 35 0.013
hexose metabolic process GO:0019318 98 0.013
positive regulation of protein transport GO:0051222 93 0.013
single organism cell adhesion GO:0098602 156 0.013
blood circulation GO:0008015 195 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.013
regulation of endocytosis GO:0030100 69 0.013
innate immune response GO:0045087 157 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
multicellular organismal homeostasis GO:0048871 164 0.012
inflammatory response GO:0006954 244 0.012
metal ion homeostasis GO:0055065 189 0.012
metencephalon development GO:0022037 89 0.012
vesicle localization GO:0051648 86 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
dephosphorylation GO:0016311 129 0.012
nucleotide catabolic process GO:0009166 217 0.012
Human
purine nucleotide catabolic process GO:0006195 211 0.012
Human
protein secretion GO:0009306 111 0.012
regulation of membrane potential GO:0042391 192 0.012
glucose homeostasis GO:0042593 128 0.012
respiratory system development GO:0060541 190 0.012
regulation of lamellipodium assembly GO:0010591 3 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
chromosome segregation GO:0007059 48 0.012
gtp catabolic process GO:0006184 143 0.012
Human
positive regulation of endocytosis GO:0045807 42 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
developmental maturation GO:0021700 193 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
leukocyte mediated immunity GO:0002443 174 0.012
peptide secretion GO:0002790 114 0.011
regulation of hormone secretion GO:0046883 88 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
Human
carbohydrate homeostasis GO:0033500 128 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
Human
cellular response to nutrient levels GO:0031669 64 0.011
limb development GO:0060173 166 0.011
post mating behavior GO:0045297 3 0.011
membrane lipid metabolic process GO:0006643 53 0.011
positive regulation of transferase activity GO:0051347 167 0.011
response to inorganic substance GO:0010035 96 0.011
regulation of peptide hormone secretion GO:0090276 75 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
midgut development GO:0007494 4 0.011
positive regulation of peptide hormone secretion GO:0090277 31 0.011
ossification GO:0001503 216 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
Human
peptidyl lysine modification GO:0018205 77 0.011
rna processing GO:0006396 105 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
neuron death GO:0070997 154 0.011
negative regulation of immune system process GO:0002683 209 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
Human
blood vessel morphogenesis GO:0048514 285 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
Human
monosaccharide metabolic process GO:0005996 106 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
cellular response to topologically incorrect protein GO:0035967 25 0.010
guanosine containing compound catabolic process GO:1901069 144 0.010
Human
tissue homeostasis GO:0001894 115 0.010
gtp metabolic process GO:0046039 144 0.010
Human
positive regulation of organelle organization GO:0010638 128 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
maintenance of location in cell GO:0051651 24 0.010
Yeast
peptidyl asparagine modification GO:0018196 1 0.010
exocytosis GO:0006887 121 0.010
glial cell differentiation GO:0010001 131 0.010
sphingolipid metabolic process GO:0006665 45 0.010
protein glycosylation GO:0006486 55 0.010
copii coated vesicle budding GO:0090114 2 0.010

Tmed2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.030
inherited metabolic disorder DOID:655 0 0.030
bone development disease DOID:0080006 0 0.013
bone disease DOID:0080001 0 0.013
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013