Mus musculus

173 known processes

Kcnma1

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

(Aliases: Slo1,BKCa,MaxiK,Slo,mSlo1,mSlo,5730414M22Rik)

Kcnma1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of neurotransmitter transport GO:0051588 35 0.991
Worm
cytoskeleton dependent intracellular transport GO:0030705 50 0.991
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.991
transmembrane transport GO:0055085 412 0.990
synaptic transmission GO:0007268 329 0.989
generation of ovulation cycle rhythm GO:0060112 1 0.986
regulation of neurotransmitter levels GO:0001505 87 0.983
Worm
microtubule based movement GO:0007018 84 0.982
potassium ion homeostasis GO:0055075 4 0.981
Human
neurotransmitter uptake GO:0001504 14 0.980
microtubule based transport GO:0010970 50 0.979
regulation of blood circulation GO:1903522 93 0.979
Rat
neurofilament cytoskeleton organization GO:0060052 10 0.977
neurotransmitter transport GO:0006836 76 0.977
Worm
cellular potassium ion transport GO:0071804 43 0.972
cation transmembrane transport GO:0098655 266 0.970
inorganic cation transmembrane transport GO:0098662 207 0.968
regulation of ion transport GO:0043269 215 0.963
positive regulation of glial cell proliferation GO:0060252 4 0.956
regulation of system process GO:0044057 200 0.956
potassium ion transmembrane transport GO:0071805 43 0.953
blood circulation GO:0008015 195 0.945
neurotransmitter secretion GO:0007269 62 0.936
Worm
striated muscle contraction GO:0006941 45 0.931
regulation of blood vessel size GO:0050880 56 0.930
smooth muscle contraction GO:0006939 44 0.930
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.927
sperm motility GO:0030317 47 0.924
acetylcholine transport GO:0015870 2 0.915
long term synaptic potentiation GO:0060291 25 0.913
schwann cell proliferation GO:0014010 2 0.912
circulatory system process GO:0003013 197 0.911
heart process GO:0003015 94 0.911
calcium ion transport GO:0006816 159 0.909
muscle contraction GO:0006936 101 0.908
regulation of blood pressure GO:0008217 93 0.907
regulation of anatomical structure size GO:0090066 178 0.902
adult behavior GO:0030534 135 0.893
acetate ester transport GO:1901374 2 0.891
urinary bladder smooth muscle contraction GO:0014832 5 0.890
intermediate filament bundle assembly GO:0045110 3 0.888
calcium ion homeostasis GO:0055074 127 0.882
regulation of membrane potential GO:0042391 192 0.880
regulation of heart contraction GO:0008016 77 0.869
acetylcholine secretion neurotransmission GO:0014055 2 0.868
visual learning GO:0008542 44 0.860
multicellular organismal signaling GO:0035637 91 0.856
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.850
potassium ion transport GO:0006813 52 0.850
peripheral nervous system axon regeneration GO:0014012 2 0.847
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.836
axon cargo transport GO:0008088 33 0.829
heart contraction GO:0060047 93 0.827
divalent inorganic cation transport GO:0072511 178 0.818
axonogenesis GO:0007409 274 0.817
lateral geniculate nucleus development GO:0021771 1 0.815
divalent metal ion transport GO:0070838 172 0.809
cellular metal ion homeostasis GO:0006875 151 0.808
Human
visual perception GO:0007601 52 0.802
gamma aminobutyric acid secretion GO:0014051 6 0.799
positive regulation of schwann cell proliferation GO:0010625 1 0.790
cellular divalent inorganic cation homeostasis GO:0072503 127 0.790
inorganic ion transmembrane transport GO:0098660 234 0.774
regulation of cell projection organization GO:0031344 206 0.769
reflex GO:0060004 22 0.764
cellular calcium ion homeostasis GO:0006874 119 0.755
regulation of circadian sleep wake cycle GO:0042749 3 0.751
visual behavior GO:0007632 45 0.741
bergmann glial cell differentiation GO:0060020 6 0.740
learning GO:0007612 98 0.736
negative regulation of hormone biosynthetic process GO:0032353 4 0.735
cytosolic calcium ion homeostasis GO:0051480 70 0.733
cation homeostasis GO:0055080 212 0.732
Human
cellular ion homeostasis GO:0006873 165 0.730
Human
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.729
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.727
muscle system process GO:0003012 141 0.726
action potential GO:0001508 78 0.724
regulation of neuron projection development GO:0010975 169 0.722
metal ion homeostasis GO:0055065 189 0.720
Human
negative regulation of neuron death GO:1901215 98 0.715
response to light stimulus GO:0009416 135 0.699
ion transmembrane transport GO:0034220 361 0.689
response to radiation GO:0009314 165 0.688
sensory perception GO:0007600 245 0.687
membrane depolarization during sa node cell action potential GO:0086046 2 0.685
calcium ion transmembrane transport GO:0070588 85 0.685
negative regulation of hormone metabolic process GO:0032351 4 0.681
vascular process in circulatory system GO:0003018 62 0.672
response to glycoside GO:1903416 2 0.670
regulation of metal ion transport GO:0010959 106 0.666
membrane depolarization GO:0051899 64 0.660
associative learning GO:0008306 61 0.658
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.658
divalent inorganic cation homeostasis GO:0072507 138 0.657
gamma aminobutyric acid transport GO:0015812 7 0.655
positive regulation of heart rate GO:0010460 10 0.649
negative regulation of action potential GO:0045759 1 0.636
regulation of neurotransmitter uptake GO:0051580 6 0.619
sensory perception of mechanical stimulus GO:0050954 107 0.611
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.608
micturition GO:0060073 6 0.608
intermediate filament cytoskeleton organization GO:0045104 26 0.601
mating behavior sex discrimination GO:0048047 1 0.600
synaptic transmission involved in micturition GO:0060084 3 0.598
sa node cell action potential GO:0086015 4 0.598
microtubule based process GO:0007017 236 0.596
norepinephrine transport GO:0015874 2 0.592
regulation of secretion by cell GO:1903530 249 0.589
Worm
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 16 0.586
intermediate filament based process GO:0045103 27 0.574
negative regulation of neuron apoptotic process GO:0043524 92 0.573
smooth muscle contraction involved in micturition GO:0060083 3 0.570
regulation of muscle contraction GO:0006937 49 0.567
regulation of tube size GO:0035150 57 0.566
synaptic transmission cholinergic GO:0007271 7 0.566
regulation of heart rate GO:0002027 36 0.549
regulation of cell projection size GO:0032536 6 0.545
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.538
positive regulation of dopamine secretion GO:0033603 2 0.522
regulation of muscle system process GO:0090257 80 0.510
detection of external stimulus GO:0009581 61 0.507
adult walking behavior GO:0007628 41 0.503
organic anion transport GO:0015711 137 0.503
locomotory behavior GO:0007626 195 0.502
regulation of vasoconstriction GO:0019229 14 0.478
intermediate filament organization GO:0045109 15 0.478
amine transport GO:0015837 21 0.472
nucleoside monophosphate metabolic process GO:0009123 85 0.470
regulation of neuron death GO:1901214 134 0.468
cation transport GO:0006812 399 0.462
regulation of neuron apoptotic process GO:0043523 122 0.459
excretion GO:0007588 22 0.445
learning or memory GO:0007611 148 0.444
positive regulation of catecholamine secretion GO:0033605 2 0.431
regulation of cellular component size GO:0032535 121 0.425
positive regulation of striated muscle contraction GO:0045989 3 0.416
anion transport GO:0006820 177 0.409
regulation of dopamine secretion GO:0014059 9 0.406
nitrogen compound transport GO:0071705 271 0.406
positive regulation of heart contraction GO:0045823 14 0.399
response to drug GO:0042493 75 0.389
Worm Fly
circadian sleep wake cycle non rem sleep GO:0042748 2 0.385
regulation of striated muscle contraction GO:0006942 25 0.383
neuromuscular process GO:0050905 99 0.378
circadian sleep wake cycle rem sleep GO:0042747 1 0.377
cellular chemical homeostasis GO:0055082 215 0.377
Human
atp metabolic process GO:0046034 75 0.373
regulation of actin filament based process GO:0032970 99 0.372
regulation of postsynaptic membrane potential GO:0060078 48 0.370
peripheral nervous system neuron axonogenesis GO:0048936 3 0.368
striated muscle adaptation GO:0014888 26 0.365
cellular amino acid metabolic process GO:0006520 103 0.362
hindbrain maturation GO:0021578 6 0.359
response to organic cyclic compound GO:0014070 198 0.358
Rat
positive regulation of ion transport GO:0043270 65 0.352
hormone biosynthetic process GO:0042446 16 0.349
regulation of neurotransmitter secretion GO:0046928 29 0.346
Worm
regulation of ion transmembrane transport GO:0034765 119 0.343
detection of abiotic stimulus GO:0009582 60 0.343
regulation of axon diameter GO:0031133 6 0.343
regulation of neuron differentiation GO:0045664 281 0.340
fluid transport GO:0042044 14 0.340
nucleotide metabolic process GO:0009117 332 0.337
nucleoside monophosphate catabolic process GO:0009125 59 0.332
sensory perception of sound GO:0007605 97 0.332
purine ribonucleoside metabolic process GO:0046128 241 0.331
rhythmic behavior GO:0007622 15 0.331
acid secretion GO:0046717 33 0.330
nucleoside triphosphate metabolic process GO:0009141 230 0.330
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.324
vasoconstriction GO:0042310 27 0.320
regulation of vesicle mediated transport GO:0060627 139 0.319
hormone metabolic process GO:0042445 86 0.313
adult locomotory behavior GO:0008344 91 0.309
circadian sleep wake cycle GO:0042745 5 0.303
purine nucleotide metabolic process GO:0006163 302 0.301
carboxylic acid transport GO:0046942 100 0.300
regulation of membrane repolarization GO:0060306 7 0.298
developmental cell growth GO:0048588 84 0.298
catecholamine transport GO:0051937 21 0.296
regulation of transmembrane transport GO:0034762 128 0.295
organonitrogen compound catabolic process GO:1901565 264 0.293
membrane organization GO:0061024 245 0.284
sensory perception of light stimulus GO:0050953 54 0.284
regulation of cellular amine metabolic process GO:0033238 20 0.282
regulation of ion transmembrane transporter activity GO:0032412 54 0.282
pons development GO:0021548 13 0.280
negative regulation of cell projection organization GO:0031345 56 0.277
purine nucleoside triphosphate metabolic process GO:0009144 226 0.275
hydrogen ion transmembrane transport GO:1902600 25 0.274
glial cell development GO:0021782 54 0.272
positive regulation of blood circulation GO:1903524 22 0.270
regulation of schwann cell proliferation GO:0010624 2 0.269
muscle adaptation GO:0043500 39 0.269
response to nicotine GO:0035094 6 0.266
negative regulation of muscle contraction GO:0045932 12 0.266
positive regulation of neuron differentiation GO:0045666 141 0.265
extracellular matrix organization GO:0030198 147 0.265
determination of left right asymmetry in nervous system GO:0035545 1 0.262
positive regulation of calcium ion transport GO:0051928 27 0.261
regulation of systemic arterial blood pressure by baroreceptor feedback GO:0003025 7 0.260
response to organonitrogen compound GO:0010243 246 0.257
synapse organization GO:0050808 125 0.255
organ growth GO:0035265 117 0.254
striated muscle tissue development GO:0014706 293 0.251
optic nerve development GO:0021554 8 0.251
epithelial cell development GO:0002064 159 0.249
central nervous system maturation GO:0021626 6 0.247
regulation of potassium ion transport GO:0043266 16 0.247
amine metabolic process GO:0009308 45 0.246
sodium ion transmembrane transport GO:0035725 49 0.244
optic nerve morphogenesis GO:0021631 6 0.244
organic hydroxy compound metabolic process GO:1901615 203 0.242
regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback GO:0001978 5 0.239
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.236
mitochondrion transport along microtubule GO:0047497 3 0.236
membrane hyperpolarization GO:0060081 21 0.235
cellular protein complex assembly GO:0043623 116 0.231
vestibular nucleus development GO:0021750 2 0.229
behavioral response to nutrient GO:0051780 1 0.229
g protein coupled receptor signaling pathway GO:0007186 243 0.227
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.225
purine ribonucleotide metabolic process GO:0009150 290 0.224
intracellular protein transport GO:0006886 204 0.220
ribose phosphate metabolic process GO:0019693 291 0.218
feeding behavior GO:0007631 62 0.212
Worm
regulation of hormone levels GO:0010817 211 0.211
dopamine transport GO:0015872 15 0.209
regulation of smooth muscle contraction GO:0006940 22 0.205
atp catabolic process GO:0006200 55 0.204
neural nucleus development GO:0048857 22 0.204
cell type specific apoptotic process GO:0097285 268 0.200
regulation of synaptic activity GO:0060025 1 0.196
establishment of mitochondrion localization GO:0051654 4 0.195
multi organism reproductive behavior GO:0044705 29 0.195
Fly
ribonucleoside metabolic process GO:0009119 245 0.194
extracellular structure organization GO:0043062 148 0.193
regulation of calcium ion transport GO:0051924 69 0.193
ribonucleoside triphosphate metabolic process GO:0009199 220 0.192
cerebellar purkinje cell layer development GO:0021680 26 0.190
positive regulation of blood pressure GO:0045777 21 0.188
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.188
response to pain GO:0048265 26 0.186
cellular amine metabolic process GO:0044106 44 0.186
regulation of amine transport GO:0051952 21 0.186
ribonucleotide metabolic process GO:0009259 291 0.184
hexose metabolic process GO:0019318 98 0.183
positive regulation of amine transport GO:0051954 8 0.182
reproductive behavior GO:0019098 32 0.182
Fly
skeletal muscle fiber development GO:0048741 58 0.180
detection of mechanical stimulus GO:0050982 27 0.180
regulation of microtubule depolymerization GO:0031114 13 0.175
detection of stimulus GO:0051606 84 0.171
smad protein signal transduction GO:0060395 21 0.170
sodium ion transport GO:0006814 73 0.169
neuron projection extension GO:1990138 64 0.167
organic hydroxy compound transport GO:0015850 93 0.167
synapse assembly GO:0007416 56 0.161
negative regulation of protein complex disassembly GO:0043242 22 0.161
microtubule polymerization or depolymerization GO:0031109 26 0.161
positive regulation of neuron projection development GO:0010976 79 0.161
hormone secretion GO:0046879 128 0.160
positive regulation of cell projection organization GO:0031346 95 0.160
cellular component assembly involved in morphogenesis GO:0010927 139 0.159
Worm
forebrain development GO:0030900 302 0.159
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.157
negative regulation of protein depolymerization GO:1901880 21 0.157
cell growth GO:0016049 130 0.156
amino acid transport GO:0006865 61 0.156
membrane repolarization GO:0086009 7 0.154
positive regulation of muscle contraction GO:0045933 10 0.153
microtubule cytoskeleton organization GO:0000226 157 0.153
cardiac muscle contraction GO:0060048 32 0.151
cellular response to hormone stimulus GO:0032870 150 0.151
camera type eye development GO:0043010 266 0.150
cellular response to lipid GO:0071396 145 0.150
aromatic compound catabolic process GO:0019439 286 0.149
cellular homeostasis GO:0019725 240 0.149
circadian behavior GO:0048512 13 0.148
purine nucleoside monophosphate metabolic process GO:0009126 81 0.148
optic nerve structural organization GO:0021633 2 0.147
establishment of organelle localization GO:0051656 122 0.145
axon regeneration GO:0031103 12 0.145
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.145
anatomical structure homeostasis GO:0060249 145 0.144
nucleobase containing small molecule metabolic process GO:0055086 352 0.143
positive regulation of growth GO:0045927 104 0.140
regulation of intracellular transport GO:0032386 159 0.139
conditioned taste aversion GO:0001661 4 0.137
neuronal action potential GO:0019228 54 0.134
regulation of synaptic vesicle priming GO:0010807 4 0.133
nucleoside phosphate metabolic process GO:0006753 338 0.133
neuron neuron synaptic transmission GO:0007270 69 0.131
purine ribonucleotide catabolic process GO:0009154 208 0.130
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.130
cerebellum maturation GO:0021590 3 0.128
central nervous system neuron axonogenesis GO:0021955 28 0.126
dopamine secretion GO:0014046 9 0.125
purine containing compound metabolic process GO:0072521 311 0.124
regulation of organ growth GO:0046620 61 0.124
purine nucleoside monophosphate catabolic process GO:0009128 58 0.124
cognition GO:0050890 149 0.123
memory GO:0007613 58 0.123
calcium ion dependent exocytosis of neurotransmitter GO:0048791 7 0.121
rhythmic process GO:0048511 174 0.119
amide transport GO:0042886 138 0.118
regulation of potassium ion transmembrane transporter activity GO:1901016 7 0.118
ribonucleoside monophosphate catabolic process GO:0009158 57 0.117
purine nucleoside triphosphate catabolic process GO:0009146 203 0.109
phenol containing compound metabolic process GO:0018958 60 0.108
cardiac muscle cell contraction GO:0086003 7 0.108
carbohydrate metabolic process GO:0005975 230 0.107
regulation of transferase activity GO:0051338 263 0.107
organophosphate catabolic process GO:0046434 232 0.106
gamma aminobutyric acid signaling pathway GO:0007214 8 0.105
neuromuscular synaptic transmission GO:0007274 16 0.103
cell cell signaling involved in lung development GO:0060495 1 0.102
regulation of transporter activity GO:0032409 57 0.102
sodium ion homeostasis GO:0055078 7 0.102
multi organism behavior GO:0051705 62 0.101
Fly
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.101
monovalent inorganic cation homeostasis GO:0055067 33 0.100
Human
negative regulation of cytoskeleton organization GO:0051494 36 0.099
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.097
ear development GO:0043583 200 0.097
ribonucleoside monophosphate metabolic process GO:0009161 80 0.096
ras protein signal transduction GO:0007265 77 0.095
dephosphorylation GO:0016311 129 0.095
musculoskeletal movement spinal reflex action GO:0050883 3 0.094
neuron death GO:0070997 154 0.092
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.091
glycosyl compound catabolic process GO:1901658 206 0.091
organelle disassembly GO:1903008 2 0.090
carbohydrate derivative catabolic process GO:1901136 231 0.088
positive regulation of protein phosphorylation GO:0001934 242 0.088
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.087
cell communication involved in cardiac conduction GO:0086065 9 0.087
extraocular skeletal muscle development GO:0002074 2 0.086
endocytosis GO:0006897 168 0.086
nucleoside catabolic process GO:0009164 206 0.085
response to steroid hormone GO:0048545 56 0.085
Rat
positive regulation of cell development GO:0010720 237 0.085
negative regulation of potassium ion transport GO:0043267 7 0.084
regulation of lipid metabolic process GO:0019216 118 0.084
muscle fiber development GO:0048747 76 0.083
skeletal muscle organ development GO:0060538 163 0.082
ovulation cycle GO:0042698 59 0.081
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.081
muscle cell development GO:0055001 133 0.081
Worm
nerve development GO:0021675 67 0.081
fertilization GO:0009566 127 0.080
response to cocaine GO:0042220 14 0.080
regulation of norepinephrine secretion GO:0014061 2 0.079
response to ammonium ion GO:0060359 21 0.078
muscle cell differentiation GO:0042692 261 0.078
Worm
medulla oblongata development GO:0021550 3 0.078
regulation of protein depolymerization GO:1901879 26 0.078
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.078
detection of stimulus involved in sensory perception GO:0050906 44 0.078
actin mediated cell contraction GO:0070252 15 0.077
substantia nigra development GO:0021762 2 0.077
regulation of secretion GO:0051046 274 0.077
Worm
nucleoside triphosphate catabolic process GO:0009143 205 0.076
gliogenesis GO:0042063 141 0.076
thyroid hormone metabolic process GO:0042403 16 0.075
developmental growth involved in morphogenesis GO:0060560 138 0.075
negative regulation of interleukin 1 beta production GO:0032691 5 0.075
respiratory gaseous exchange GO:0007585 43 0.075
exocytosis GO:0006887 121 0.075
generation of precursor metabolites and energy GO:0006091 103 0.073
regulation of hydrolase activity GO:0051336 246 0.073
endoplasmic reticulum organization GO:0007029 10 0.073
positive regulation of necrotic cell death GO:0010940 1 0.072
skeletal muscle adaptation GO:0043501 16 0.072
protein depolymerization GO:0051261 34 0.072
synaptic transmission glutamatergic GO:0035249 36 0.071
regulation of catecholamine secretion GO:0050433 12 0.071
norepinephrine secretion GO:0048243 2 0.071
transmission of nerve impulse GO:0019226 76 0.070
negative regulation of cytosolic calcium ion concentration GO:0051481 2 0.070
organic acid transport GO:0015849 101 0.070
cell junction organization GO:0034330 77 0.069
regulation of defense response GO:0031347 233 0.069
catecholamine secretion GO:0050432 15 0.066
protein complex disassembly GO:0043241 40 0.066
response to alkaloid GO:0043279 34 0.066
nucleoside metabolic process GO:0009116 246 0.066
development of primary sexual characteristics GO:0045137 143 0.066
purine ribonucleoside catabolic process GO:0046130 205 0.066
second messenger mediated signaling GO:0019932 73 0.065
maternal determination of anterior posterior axis embryo GO:0008358 2 0.065
regulation of synaptic vesicle transport GO:1902803 13 0.065
purine nucleoside catabolic process GO:0006152 205 0.065
regulation of dopamine metabolic process GO:0042053 10 0.064
negative regulation of cellular component organization GO:0051129 194 0.064
astrocyte development GO:0014002 12 0.064
retina homeostasis GO:0001895 23 0.063
plasma membrane organization GO:0007009 90 0.063
monocarboxylic acid transport GO:0015718 44 0.062
peptide hormone secretion GO:0030072 109 0.062
regulation of exocytosis GO:0017157 61 0.062
protein localization to membrane GO:0072657 108 0.061
multicellular organismal response to stress GO:0033555 62 0.061
positive regulation of protein kinase activity GO:0045860 144 0.060
actin filament based movement GO:0030048 23 0.059
sulfur amino acid metabolic process GO:0000096 9 0.059
social behavior GO:0035176 21 0.059
muscle tissue development GO:0060537 308 0.059
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.059
regulation of action potential GO:0098900 4 0.058
ionotropic glutamate receptor signaling pathway GO:0035235 29 0.058
cerebellum development GO:0021549 77 0.057
detection of light stimulus GO:0009583 25 0.057
neuron apoptotic process GO:0051402 142 0.056
regulation of lipid biosynthetic process GO:0046890 54 0.056
mating GO:0007618 27 0.056
Fly
regulation of kinase activity GO:0043549 249 0.056
cellular response to organonitrogen compound GO:0071417 145 0.056
multicellular organismal homeostasis GO:0048871 164 0.055
spinal cord development GO:0021510 81 0.055
regulation of response to drug GO:2001023 2 0.054
peptide transport GO:0015833 133 0.054
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.054
oocyte construction GO:0007308 2 0.054
regulation of synaptic plasticity GO:0048167 87 0.053
tissue homeostasis GO:0001894 115 0.053
regulation of feeding behavior GO:0060259 3 0.053
neuromuscular process controlling balance GO:0050885 59 0.053
response to temperature stimulus GO:0009266 55 0.053
regulation of the force of heart contraction GO:0002026 17 0.052
male gamete generation GO:0048232 285 0.052
purine containing compound catabolic process GO:0072523 213 0.052
defecation GO:0030421 1 0.051
renal system development GO:0072001 225 0.051
protein polymerization GO:0051258 57 0.051
protein targeting GO:0006605 143 0.050
response to metal ion GO:0010038 47 0.050
Human Rat
sodium ion export GO:0071436 2 0.050
striated muscle cell development GO:0055002 125 0.050
Worm
cellular response to steroid hormone stimulus GO:0071383 33 0.050
multi multicellular organism process GO:0044706 109 0.050
Fly
actin filament organization GO:0007015 113 0.049
regulation of protein complex disassembly GO:0043244 28 0.049
myotube cell development GO:0014904 60 0.049
synaptic vesicle membrane organization GO:0048499 1 0.049
lens development in camera type eye GO:0002088 62 0.049
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.049
glycosyl compound metabolic process GO:1901657 246 0.048
posttranscriptional regulation of gene expression GO:0010608 155 0.048
sleep GO:0030431 7 0.048
macromolecular complex disassembly GO:0032984 43 0.048
regulation of nucleotide catabolic process GO:0030811 122 0.048
regulation of circadian rhythm GO:0042752 58 0.047
gonad development GO:0008406 141 0.047
positive regulation of ion transmembrane transport GO:0034767 24 0.046
ribonucleoside triphosphate catabolic process GO:0009203 199 0.046
multicellular organismal reproductive behavior GO:0033057 23 0.045
Fly
regulation of extent of cell growth GO:0061387 52 0.044
ribonucleotide catabolic process GO:0009261 208 0.044
regulation of synaptic vesicle exocytosis GO:2000300 11 0.044
heterocycle catabolic process GO:0046700 280 0.044
cardiac muscle cell action potential GO:0086001 11 0.044
pole plasm assembly GO:0007315 2 0.044
membrane depolarization during cardiac muscle cell action potential GO:0086012 5 0.044
proton transport GO:0015992 35 0.043
regulation of potassium ion transmembrane transport GO:1901379 11 0.043
response to oxygen levels GO:0070482 62 0.043
cellular response to cytokine stimulus GO:0071345 189 0.042
regulation of steroid biosynthetic process GO:0050810 26 0.042
regulation of steroid hormone biosynthetic process GO:0090030 4 0.042
oocyte anterior posterior axis specification GO:0007314 2 0.042
positive regulation of vasoconstriction GO:0045907 4 0.042
cardiac conduction GO:0061337 17 0.042
glycolytic process GO:0006096 20 0.042
establishment of glial blood brain barrier GO:0060857 2 0.041
regulation of homeostatic process GO:0032844 182 0.041
regulation of calcium ion transmembrane transport GO:1903169 20 0.041
sensory perception of pain GO:0019233 47 0.041
oocyte axis specification GO:0007309 2 0.041
regulation of respiratory system process GO:0044065 13 0.041
ribonucleoside catabolic process GO:0042454 206 0.041
digestive tract development GO:0048565 190 0.040
regulation of cytoplasmic transport GO:1903649 112 0.040
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 1 0.039
monosaccharide metabolic process GO:0005996 106 0.039
nucleotide catabolic process GO:0009166 217 0.039
cellular response to organic cyclic compound GO:0071407 87 0.039
regulation of axon extension GO:0030516 43 0.039
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.038
membrane depolarization during action potential GO:0086010 5 0.038

Kcnma1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.549
nervous system disease DOID:863 0 0.549
central nervous system disease DOID:331 0 0.343
brain disease DOID:936 0 0.343
neuromuscular disease DOID:440 0 0.152
neuropathy DOID:870 0 0.152
charcot marie tooth disease DOID:10595 0 0.093
sensory system disease DOID:0050155 0 0.053