Mus musculus

87 known processes

Cep290

centrosomal protein 290

(Aliases: BC004690,Nphp6,MGC7859)

Cep290 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 81 0.996
cilium morphogenesis GO:0060271 102 0.991
intraciliary transport GO:0042073 9 0.963
cytoskeleton dependent intracellular transport GO:0030705 50 0.952
microtubule based movement GO:0007018 84 0.903
microtubule based transport GO:0010970 50 0.786
cellular component assembly involved in morphogenesis GO:0010927 139 0.785
nucleoside phosphate metabolic process GO:0006753 338 0.736
microtubule anchoring at microtubule organizing center GO:0072393 5 0.696
organelle assembly GO:0070925 177 0.600
maintenance of location GO:0051235 89 0.431
nucleobase containing small molecule metabolic process GO:0055086 352 0.400
regulation of intracellular transport GO:0032386 159 0.326
nucleotide metabolic process GO:0009117 332 0.321
microtubule based process GO:0007017 236 0.248
regulation of blood circulation GO:1903522 93 0.241
photoreceptor cell development GO:0042461 40 0.206
Zebrafish
positive regulation of hydrolase activity GO:0051345 148 0.199
membrane organization GO:0061024 245 0.197
cytoplasmic transport GO:0016482 234 0.179
regulation of ryanodine sensitive calcium release channel activity GO:0060314 10 0.167
nucleus localization GO:0051647 20 0.166
intracellular protein transport GO:0006886 204 0.165
regulation of nucleotide metabolic process GO:0006140 169 0.160
purine nucleoside catabolic process GO:0006152 205 0.156
stem cell development GO:0048864 219 0.154
nucleotide catabolic process GO:0009166 217 0.137
purine nucleotide metabolic process GO:0006163 302 0.135
ribonucleoside triphosphate catabolic process GO:0009203 199 0.125
nucleoside triphosphate catabolic process GO:0009143 205 0.125
photoreceptor cell differentiation GO:0046530 52 0.125
Zebrafish
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.121
regulation of binding GO:0051098 111 0.119
cation transmembrane transport GO:0098655 266 0.119
cellular nitrogen compound catabolic process GO:0044270 280 0.115
nucleoside monophosphate metabolic process GO:0009123 85 0.111
inorganic cation transmembrane transport GO:0098662 207 0.109
forebrain development GO:0030900 302 0.108
purine nucleotide catabolic process GO:0006195 211 0.106
organelle localization GO:0051640 179 0.106
purine containing compound catabolic process GO:0072523 213 0.103
glycosyl compound catabolic process GO:1901658 206 0.103
microtubule organizing center organization GO:0031023 28 0.097
sequestering of calcium ion GO:0051208 18 0.097
nucleoside metabolic process GO:0009116 246 0.093
purine ribonucleotide catabolic process GO:0009154 208 0.092
purine containing compound metabolic process GO:0072521 311 0.088
ribonucleoside catabolic process GO:0042454 206 0.087
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.086
organophosphate catabolic process GO:0046434 232 0.085
interkinetic nuclear migration GO:0022027 8 0.084
muscle system process GO:0003012 141 0.080
transmembrane transport GO:0055085 412 0.079
establishment of organelle localization GO:0051656 122 0.078
regulation of ion transmembrane transport GO:0034765 119 0.077
regulation of cell cycle GO:0051726 281 0.077
cation homeostasis GO:0055080 212 0.076
purine nucleoside triphosphate catabolic process GO:0009146 203 0.076
inorganic ion transmembrane transport GO:0098660 234 0.075
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.072
nucleoside phosphate catabolic process GO:1901292 222 0.069
positive regulation of phosphoprotein phosphatase activity GO:0032516 1 0.069
atp metabolic process GO:0046034 75 0.069
protein catabolic process GO:0030163 221 0.069
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.066
purine nucleoside metabolic process GO:0042278 241 0.066
intraciliary retrograde transport GO:0035721 3 0.065
ribonucleoside metabolic process GO:0009119 245 0.065
protein localization to organelle GO:0033365 185 0.064
microtubule cytoskeleton organization GO:0000226 157 0.063
purine ribonucleoside catabolic process GO:0046130 205 0.061
stem cell maintenance GO:0019827 130 0.061
regulation of establishment of protein localization GO:0070201 181 0.061
regulation of muscle contraction GO:0006937 49 0.059
protein ubiquitination GO:0016567 171 0.059
calcium ion homeostasis GO:0055074 127 0.059
cellular macromolecule catabolic process GO:0044265 206 0.058
ribonucleotide metabolic process GO:0009259 291 0.057
atp catabolic process GO:0006200 55 0.057
protein modification by small protein conjugation or removal GO:0070647 207 0.057
cardiac muscle contraction GO:0060048 32 0.056
cytoplasmic microtubule organization GO:0031122 14 0.055
microtubule anchoring GO:0034453 9 0.054
regulation of muscle system process GO:0090257 80 0.054
maintenance of location in cell GO:0051651 24 0.053
cellular ion homeostasis GO:0006873 165 0.053
cellular homeostasis GO:0019725 240 0.052
positive regulation of nucleotide metabolic process GO:0045981 114 0.052
striated muscle contraction GO:0006941 45 0.051
neural nucleus development GO:0048857 22 0.051
divalent inorganic cation transport GO:0072511 178 0.050
cation transport GO:0006812 399 0.050
regulation of transmembrane transport GO:0034762 128 0.050
cellular metal ion homeostasis GO:0006875 151 0.050
eye photoreceptor cell differentiation GO:0001754 41 0.049
Zebrafish
protein processing GO:0016485 163 0.049
calcium ion transmembrane transport GO:0070588 85 0.048
positive regulation of protein transport GO:0051222 93 0.048
nucleoside triphosphate metabolic process GO:0009141 230 0.047
regulation of hydrolase activity GO:0051336 246 0.047
positive regulation of intracellular protein transport GO:0090316 42 0.047
divalent inorganic cation homeostasis GO:0072507 138 0.046
purine nucleoside triphosphate metabolic process GO:0009144 226 0.045
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.045
regulation of system process GO:0044057 200 0.045
regulation of protein transport GO:0051223 163 0.045
ribonucleoside monophosphate metabolic process GO:0009161 80 0.044
protein localization to membrane GO:0072657 108 0.043
positive regulation of protein modification process GO:0031401 299 0.043
nucleoside catabolic process GO:0009164 206 0.042
response to inorganic substance GO:0010035 96 0.042
camera type eye development GO:0043010 266 0.042
cellular divalent inorganic cation homeostasis GO:0072503 127 0.041
metal ion homeostasis GO:0055065 189 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.040
aromatic compound catabolic process GO:0019439 286 0.040
divalent metal ion transport GO:0070838 172 0.040
macromolecule catabolic process GO:0009057 281 0.040
substantia nigra development GO:0021762 2 0.040
regulation of metal ion transport GO:0010959 106 0.040
ribonucleoside triphosphate metabolic process GO:0009199 220 0.038
embryonic organ morphogenesis GO:0048562 276 0.038
Zebrafish
regulation of intracellular protein transport GO:0033157 82 0.037
ribose phosphate metabolic process GO:0019693 291 0.037
regulation of cardiac muscle contraction GO:0055117 21 0.037
chemotaxis GO:0006935 247 0.036
circulatory system process GO:0003013 197 0.036
cyclic nucleotide metabolic process GO:0009187 59 0.036
purine nucleoside monophosphate catabolic process GO:0009128 58 0.036
male meiosis i GO:0007141 16 0.036
organonitrogen compound catabolic process GO:1901565 264 0.036
regulation of ion transport GO:0043269 215 0.036
calcium ion transport GO:0006816 159 0.036
glycosyl compound metabolic process GO:1901657 246 0.035
stem cell differentiation GO:0048863 268 0.035
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.035
ion transmembrane transport GO:0034220 361 0.035
amine metabolic process GO:0009308 45 0.035
heterocycle catabolic process GO:0046700 280 0.035
purine ribonucleoside metabolic process GO:0046128 241 0.034
regulation of striated muscle contraction GO:0006942 25 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
digestive tract morphogenesis GO:0048546 147 0.032
Zebrafish
cell proliferation in forebrain GO:0021846 30 0.031
ribonucleotide catabolic process GO:0009261 208 0.031
nucleoside monophosphate catabolic process GO:0009125 59 0.031
regulation of cytoplasmic transport GO:1903649 112 0.031
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.030
negative regulation of nervous system development GO:0051961 156 0.030
positive regulation of calcium ion transport GO:0051928 27 0.030
male meiosis GO:0007140 37 0.029
neural precursor cell proliferation GO:0061351 121 0.029
regulation of protein maturation GO:1903317 96 0.029
cellular chemical homeostasis GO:0055082 215 0.028
cellular amine metabolic process GO:0044106 44 0.028
cell cycle g2 m phase transition GO:0044839 20 0.028
response to calcium ion GO:0051592 20 0.027
negative regulation of cell development GO:0010721 169 0.027
regulation of transferase activity GO:0051338 263 0.027
sensory organ morphogenesis GO:0090596 242 0.027
Zebrafish
small gtpase mediated signal transduction GO:0007264 97 0.027
nucleocytoplasmic transport GO:0006913 139 0.026
endomembrane system organization GO:0010256 147 0.026
axonogenesis GO:0007409 274 0.026
dephosphorylation GO:0016311 129 0.026
single organism nuclear import GO:1902593 95 0.026
midbrain development GO:0030901 35 0.026
regulation of ion homeostasis GO:2000021 64 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
determination of left right symmetry GO:0007368 80 0.025
digestive system development GO:0055123 200 0.025
Zebrafish
regulation of homeostatic process GO:0032844 182 0.025
protein depolymerization GO:0051261 34 0.025
cytosolic calcium ion transport GO:0060401 48 0.024
cellular ketone metabolic process GO:0042180 84 0.024
cell type specific apoptotic process GO:0097285 268 0.024
regulation of heart contraction GO:0008016 77 0.024
regulation of neurotransmitter levels GO:0001505 87 0.024
microtubule anchoring at centrosome GO:0034454 3 0.024
regulation of calcium ion transport into cytosol GO:0010522 31 0.024
cellular calcium ion homeostasis GO:0006874 119 0.024
neuron projection extension GO:1990138 64 0.023
cellular protein complex assembly GO:0043623 116 0.023
anatomical structure homeostasis GO:0060249 145 0.023
protein localization to microtubule cytoskeleton GO:0072698 8 0.023
response to interleukin 4 GO:0070670 23 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
ras protein signal transduction GO:0007265 77 0.023
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
regulation of cellular ketone metabolic process GO:0010565 66 0.022
developmental growth involved in morphogenesis GO:0060560 138 0.022
ribonucleoside monophosphate catabolic process GO:0009158 57 0.022
heart contraction GO:0060047 93 0.022
sensory perception GO:0007600 245 0.022
calcium ion transport into cytosol GO:0060402 48 0.022
positive regulation of ion transmembrane transport GO:0034767 24 0.021
regulation of protein localization GO:0032880 231 0.021
neuron projection guidance GO:0097485 141 0.021
protein maturation GO:0051604 176 0.021
cell growth GO:0016049 130 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
regulation of transporter activity GO:0032409 57 0.021
muscle cell differentiation GO:0042692 261 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
purine nucleoside monophosphate metabolic process GO:0009126 81 0.020
neurotransmitter transport GO:0006836 76 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
cytosolic calcium ion homeostasis GO:0051480 70 0.020
endoplasmic reticulum to cytosol transport GO:1903513 12 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
positive regulation of binding GO:0051099 49 0.019
protein refolding GO:0042026 1 0.019
cellular amino acid metabolic process GO:0006520 103 0.019
maintenance of protein location in cell GO:0032507 20 0.019
axon guidance GO:0007411 141 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
meiosis i GO:0007127 60 0.019
regulation of cation channel activity GO:2001257 22 0.019
positive regulation of ion transport GO:0043270 65 0.018
organelle disassembly GO:1903008 2 0.018
muscle contraction GO:0006936 101 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.018
regulation of heart rate GO:0002027 36 0.017
positive regulation of transferase activity GO:0051347 167 0.017
blood circulation GO:0008015 195 0.017
protein targeting GO:0006605 143 0.017
photoreceptor cell morphogenesis GO:0008594 3 0.017
positive regulation of cell death GO:0010942 224 0.017
response to organonitrogen compound GO:0010243 246 0.017
olfactory learning GO:0008355 2 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
negative regulation of proteolysis GO:0045861 74 0.016
epithelial tube formation GO:0072175 130 0.016
negative regulation of homeostatic process GO:0032845 71 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
heart process GO:0003015 94 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
somatic diversification of immunoglobulins GO:0016445 43 0.016
regulation of cell shape GO:0008360 39 0.016
tissue homeostasis GO:0001894 115 0.015
telencephalon development GO:0021537 186 0.015
multicellular organism growth GO:0035264 161 0.015
protein import GO:0017038 101 0.015
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.015
regulation of protein processing GO:0070613 96 0.015
learning GO:0007612 98 0.015
cell recognition GO:0008037 83 0.015
protein localization to cytoskeleton GO:0044380 9 0.014
response to growth factor GO:0070848 198 0.014
regulation of protein dephosphorylation GO:0035304 4 0.014
response to metal ion GO:0010038 47 0.014
regulation of dna binding GO:0051101 39 0.014
b cell activation GO:0042113 161 0.014
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.014
sensory perception of light stimulus GO:0050953 54 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
positive regulation of transmembrane transport GO:0034764 29 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
regulation of protein ubiquitination GO:0031396 52 0.014
oocyte anterior posterior axis specification GO:0007314 2 0.014
alcohol metabolic process GO:0006066 116 0.014
protein localization to mitochondrion GO:0070585 15 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
actin filament based movement GO:0030048 23 0.013
protein polymerization GO:0051258 57 0.013
feeding behavior GO:0007631 62 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
cellular protein catabolic process GO:0044257 155 0.013
potassium ion homeostasis GO:0055075 4 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
male sex differentiation GO:0046661 109 0.013
lymphocyte differentiation GO:0030098 242 0.013
regulation of ion transmembrane transporter activity GO:0032412 54 0.013
positive regulation of cation channel activity GO:2001259 8 0.013
plasma membrane organization GO:0007009 90 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
dna modification GO:0006304 50 0.013
positive regulation of phosphatase activity GO:0010922 4 0.013
primary neural tube formation GO:0014020 95 0.012
response to oxygen levels GO:0070482 62 0.012
regulation of kinase activity GO:0043549 249 0.012
immune effector process GO:0002252 321 0.012
cytokinesis GO:0000910 17 0.012
protein localization to nucleus GO:0034504 121 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
t cell activation GO:0042110 289 0.012
neurotransmitter secretion GO:0007269 62 0.012
establishment of vesicle localization GO:0051650 81 0.012
regulation of cytokinesis GO:0032465 5 0.012
connective tissue development GO:0061448 179 0.012
response to reactive oxygen species GO:0000302 56 0.012
regulation of cellular response to stress GO:0080135 159 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
mitochondrion organization GO:0007005 134 0.012
spermatogenesis GO:0007283 284 0.012
establishment of protein localization to membrane GO:0090150 54 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
gastrulation GO:0007369 116 0.012
Zebrafish
regulation of cellular amine metabolic process GO:0033238 20 0.012
striated muscle cell development GO:0055002 125 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
digestive tract development GO:0048565 190 0.011
Zebrafish
g protein coupled receptor signaling pathway GO:0007186 243 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
cellular protein complex disassembly GO:0043624 36 0.011
skeletal system development GO:0001501 356 0.011
dna metabolic process GO:0006259 303 0.011
actin mediated cell contraction GO:0070252 15 0.011
response to oxidative stress GO:0006979 123 0.011
wnt signaling pathway GO:0016055 188 0.011
placenta development GO:0001890 140 0.011
respiratory system development GO:0060541 190 0.011
action potential GO:0001508 78 0.011
cellular response to interleukin 4 GO:0071353 21 0.011
ventricular system development GO:0021591 27 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
cilium movement GO:0003341 28 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
t cell differentiation in thymus GO:0033077 77 0.011
regulation of cell division GO:0051302 76 0.011
dorsal ventral axon guidance GO:0033563 3 0.011
telomere maintenance GO:0000723 19 0.010
hindbrain development GO:0030902 128 0.010
Zebrafish
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.010
stress granule disassembly GO:0035617 2 0.010
centrosome organization GO:0051297 26 0.010
neuronal action potential GO:0019228 54 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
methylation GO:0032259 134 0.010

Cep290 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.412
cancer DOID:162 0 0.351
organ system cancer DOID:0050686 0 0.266
endocrine gland cancer DOID:170 0 0.095
disease of anatomical entity DOID:7 0 0.082
nervous system disease DOID:863 0 0.082
retinal disease DOID:5679 0 0.044
retinal degeneration DOID:8466 0 0.044
sensory system disease DOID:0050155 0 0.044
eye and adnexa disease DOID:1492 0 0.044
eye disease DOID:5614 0 0.044
thyroid cancer DOID:1781 0 0.019
retinitis pigmentosa DOID:10584 0 0.012
central nervous system disease DOID:331 0 0.010
neurodegenerative disease DOID:1289 0 0.010