Mus musculus

11 known processes

Klk1b9

kallikrein 1-related peptidase b9

(Aliases: mGk-9,Klk9,Egfbp-3,Egfbp3)

Klk1b9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
kinin cascade GO:0002254 2 0.880
Mouse
tissue kallikrein kinin cascade GO:0002255 1 0.875
Mouse
left ventricular cardiac muscle tissue morphogenesis GO:0003220 2 0.870
Mouse
negative regulation of neuron projection regeneration GO:0070571 3 0.781
Mouse
positive regulation of vasoconstriction GO:0045907 4 0.779
Rat
protein activation cascade GO:0072376 19 0.736
Mouse
binding of sperm to zona pellucida GO:0007339 34 0.539
Mouse
positive regulation of lipid kinase activity GO:0090218 11 0.419
Mouse
bradykinin biosynthetic process GO:0002936 1 0.360
Mouse
phospholipid metabolic process GO:0006644 87 0.349
Mouse
protein maturation GO:0051604 176 0.332
regulation of membrane potential GO:0042391 192 0.328
brain renin angiotensin system GO:0002035 5 0.322
Mouse
circulatory system process GO:0003013 197 0.319
Mouse Rat
sperm egg recognition GO:0035036 37 0.305
Mouse
peptide metabolic process GO:0006518 46 0.277
Mouse
striated muscle contraction GO:0006941 45 0.276
Mouse
cellular amide metabolic process GO:0043603 58 0.273
Mouse
vasodilation GO:0042311 28 0.266
Mouse
muscle contraction GO:0006936 101 0.265
Mouse
action potential GO:0001508 78 0.262
keratinocyte proliferation GO:0043616 21 0.260
Mouse
cell cell recognition GO:0009988 44 0.258
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.242
Mouse
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.236
Mouse
inflammatory response GO:0006954 244 0.231
Mouse
regulation of kinase activity GO:0043549 249 0.230
Mouse
heart process GO:0003015 94 0.229
Mouse
regulation of tube size GO:0035150 57 0.221
Mouse Rat
heart morphogenesis GO:0003007 178 0.216
Mouse
protein catabolic process GO:0030163 221 0.213
Mouse
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.211
Mouse
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.210
Mouse
cognition GO:0050890 149 0.208
Mouse
heart contraction GO:0060047 93 0.205
Mouse
zymogen activation GO:0031638 41 0.204
cellular lipid metabolic process GO:0044255 323 0.198
Mouse
negative regulation of neuron projection development GO:0010977 50 0.197
Mouse
ensheathment of neurons GO:0007272 76 0.194
Mouse
blood circulation GO:0008015 195 0.194
Mouse Rat
regulation of neuron projection development GO:0010975 169 0.193
Mouse
macromolecule catabolic process GO:0009057 281 0.192
Mouse
regulation of myelination GO:0031641 20 0.185
Mouse
transmission of nerve impulse GO:0019226 76 0.185
protein processing GO:0016485 163 0.182
memory GO:0007613 58 0.179
Mouse
learning or memory GO:0007611 148 0.173
Mouse
regulation of blood vessel size GO:0050880 56 0.170
Mouse Rat
regulation of blood pressure GO:0008217 93 0.169
Mouse
regulation of system process GO:0044057 200 0.168
Mouse Rat
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.167
Mouse
striated muscle tissue development GO:0014706 293 0.165
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.161
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.160
Mouse
regulation of transferase activity GO:0051338 263 0.159
Mouse
neuronal action potential GO:0019228 54 0.157
fertilization GO:0009566 127 0.156
Mouse
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 11 0.151
Mouse
regulation of blood volume by renin angiotensin GO:0002016 7 0.149
Mouse
regulation of blood circulation GO:1903522 93 0.145
Rat
regulation of neuron projection regeneration GO:0070570 7 0.143
Mouse
positive regulation of transferase activity GO:0051347 167 0.140
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.134
Mouse
multicellular organismal signaling GO:0035637 91 0.133
cardiac muscle contraction GO:0060048 32 0.132
Mouse
regulation of lipid kinase activity GO:0043550 14 0.130
Mouse
cardiac left ventricle morphogenesis GO:0003214 9 0.125
Mouse
transmembrane transport GO:0055085 412 0.118
cardiac ventricle morphogenesis GO:0003208 50 0.117
Mouse
cardiac ventricle development GO:0003231 83 0.110
Mouse
synapse organization GO:0050808 125 0.108
Mouse
peptide biosynthetic process GO:0043043 11 0.104
Mouse
regulation of cell projection organization GO:0031344 206 0.101
Mouse
muscle system process GO:0003012 141 0.101
Mouse
extracellular structure organization GO:0043062 148 0.101
Mouse
muscle tissue development GO:0060537 308 0.096
Mouse
myelination GO:0042552 74 0.096
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.096
Mouse
endocrine process GO:0050886 39 0.095
Mouse
single fertilization GO:0007338 82 0.090
Mouse
extracellular matrix organization GO:0030198 147 0.088
Mouse
cell recognition GO:0008037 83 0.086
Mouse
regulation of neuron differentiation GO:0045664 281 0.086
Mouse
ion transmembrane transport GO:0034220 361 0.083
negative regulation of response to wounding GO:1903035 77 0.080
Mouse
cation transport GO:0006812 399 0.079
negative regulation of cell projection organization GO:0031345 56 0.079
Mouse
cardiac muscle tissue development GO:0048738 130 0.077
Mouse
regulation of response to wounding GO:1903034 189 0.075
Mouse
positive regulation of kinase activity GO:0033674 155 0.075
Mouse
nitrogen compound transport GO:0071705 271 0.074
regulation of anatomical structure size GO:0090066 178 0.074
Mouse Rat
axon ensheathment GO:0008366 76 0.071
Mouse
regulation of cellular response to stress GO:0080135 159 0.070
Mouse
regulation of lipid metabolic process GO:0019216 118 0.064
Mouse
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.063
Mouse
cardiac chamber development GO:0003205 108 0.062
Mouse
odontogenesis GO:0042476 78 0.062
Mouse
negative regulation of cellular component organization GO:0051129 194 0.060
Mouse
muscle tissue morphogenesis GO:0060415 53 0.060
Mouse
negative regulation of neurological system process GO:0031645 7 0.060
Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.058
Mouse
regulation of neurological system process GO:0031644 22 0.058
Mouse
positive regulation of blood circulation GO:1903524 22 0.056
Rat
epithelial cell proliferation GO:0050673 174 0.055
Mouse
vascular process in circulatory system GO:0003018 62 0.055
Mouse Rat
ventricular cardiac muscle tissue development GO:0003229 38 0.054
Mouse
vasoconstriction GO:0042310 27 0.053
Rat
carbohydrate derivative biosynthetic process GO:1901137 183 0.052
positive regulation of lipid metabolic process GO:0045834 40 0.050
Mouse
amine metabolic process GO:0009308 45 0.047
nucleotide metabolic process GO:0009117 332 0.043
odontogenesis of dentin containing tooth GO:0042475 66 0.043
Mouse
negative regulation of nervous system development GO:0051961 156 0.042
Mouse
spermatogenesis GO:0007283 284 0.042
sterol homeostasis GO:0055092 45 0.041
regulation of body fluid levels GO:0050878 162 0.041
synaptic transmission GO:0007268 329 0.039
Mouse
male gamete generation GO:0048232 285 0.038
maintenance of location GO:0051235 89 0.037
lipid localization GO:0010876 126 0.036
cellular amino acid metabolic process GO:0006520 103 0.035
organic hydroxy compound transport GO:0015850 93 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
amide transport GO:0042886 138 0.033
acute inflammatory response GO:0002526 41 0.032
Mouse
cellular amine metabolic process GO:0044106 44 0.032
negative regulation of myelination GO:0031642 6 0.031
Mouse
regulation of ion transport GO:0043269 215 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.030
cellular ketone metabolic process GO:0042180 84 0.030
monocarboxylic acid metabolic process GO:0032787 191 0.029
amide biosynthetic process GO:0043604 16 0.029
Mouse
amelogenesis GO:0097186 12 0.029
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.028
negative regulation of cholesterol transport GO:0032375 4 0.028
cation transmembrane transport GO:0098655 266 0.028
regeneration GO:0031099 38 0.028
Mouse
blastocyst development GO:0001824 80 0.028
organic acid biosynthetic process GO:0016053 86 0.028
negative regulation of neuron differentiation GO:0045665 101 0.026
Mouse
membrane organization GO:0061024 245 0.026
positive regulation of cell death GO:0010942 224 0.026
small molecule biosynthetic process GO:0044283 132 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
response to organonitrogen compound GO:0010243 246 0.026
negative regulation of cell development GO:0010721 169 0.025
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.025
endomembrane system organization GO:0010256 147 0.025
skin development GO:0043588 220 0.025
peptide secretion GO:0002790 114 0.025
sensory perception of sound GO:0007605 97 0.025
oxidation reduction process GO:0055114 342 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
organic anion transport GO:0015711 137 0.025
sterol transport GO:0015918 38 0.025
negative regulation of protein metabolic process GO:0051248 282 0.024
carbohydrate metabolic process GO:0005975 230 0.023
organophosphate biosynthetic process GO:0090407 122 0.022
cholesterol transport GO:0030301 38 0.022
cellular homeostasis GO:0019725 240 0.022
regulation of vasoconstriction GO:0019229 14 0.022
Rat
purine ribonucleotide metabolic process GO:0009150 290 0.022
multicellular organism growth GO:0035264 161 0.021
lipid transport GO:0006869 98 0.021
respiratory system development GO:0060541 190 0.021
regulation of secretion GO:0051046 274 0.021
response to organic cyclic compound GO:0014070 198 0.021
organelle fission GO:0048285 170 0.021
glucose homeostasis GO:0042593 128 0.021
ribose phosphate metabolic process GO:0019693 291 0.020
carboxylic acid biosynthetic process GO:0046394 86 0.020
purine containing compound metabolic process GO:0072521 311 0.020
regulation of cytokine production GO:0001817 266 0.020
response to extracellular stimulus GO:0009991 127 0.020
divalent metal ion transport GO:0070838 172 0.020
nucleoside metabolic process GO:0009116 246 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
neuron projection regeneration GO:0031102 14 0.020
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.019
wnt signaling pathway GO:0016055 188 0.019
axon regeneration GO:0031103 12 0.019
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
regulation of secretion by cell GO:1903530 249 0.019
spermatid development GO:0007286 108 0.019
negative regulation of immune system process GO:0002683 209 0.019
myeloid cell differentiation GO:0030099 233 0.018
regulation of cell activation GO:0050865 289 0.018
purine containing compound catabolic process GO:0072523 213 0.018
regulation of cellular ketone metabolic process GO:0010565 66 0.018
anion transport GO:0006820 177 0.018
blastocyst growth GO:0001832 23 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
negative regulation of protein modification process GO:0031400 163 0.018
spermatid differentiation GO:0048515 115 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
cellular response to lipid GO:0071396 145 0.018
regulation of cell division GO:0051302 76 0.018
homeostasis of number of cells GO:0048872 210 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
lipid homeostasis GO:0055088 63 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
sphingolipid metabolic process GO:0006665 45 0.017
negative regulation of sterol transport GO:0032372 4 0.017
lipid biosynthetic process GO:0008610 179 0.017
nuclear division GO:0000280 158 0.017
sensory organ morphogenesis GO:0090596 242 0.017
cytoplasmic transport GO:0016482 234 0.017
peptide hormone secretion GO:0030072 109 0.017
digestion GO:0007586 40 0.017
aromatic compound catabolic process GO:0019439 286 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
cellular calcium ion homeostasis GO:0006874 119 0.017
regulation of intracellular transport GO:0032386 159 0.016
peptide transport GO:0015833 133 0.016
regulation of transmembrane transport GO:0034762 128 0.016
intestinal epithelial structure maintenance GO:0060729 4 0.016
striated muscle myosin thick filament assembly GO:0071688 1 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
methylation GO:0032259 134 0.016
inner cell mass cell proliferation GO:0001833 15 0.016
cytokine production GO:0001816 319 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
response to nutrient levels GO:0031667 109 0.015
cholesterol homeostasis GO:0042632 44 0.015
regulation of sterol transport GO:0032371 17 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
sulfur compound metabolic process GO:0006790 100 0.015
sperm motility GO:0030317 47 0.015
glutathione metabolic process GO:0006749 16 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
germ cell development GO:0007281 185 0.015
c21 steroid hormone biosynthetic process GO:0006700 3 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.014
amino acid transport GO:0006865 61 0.014
regulation of metal ion transport GO:0010959 106 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
heterocycle catabolic process GO:0046700 280 0.014
alpha amino acid metabolic process GO:1901605 59 0.014
gland development GO:0048732 330 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
regulation of peptide transport GO:0090087 91 0.014
nucleoside catabolic process GO:0009164 206 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of protein localization GO:0032880 231 0.013
regulation of defense response GO:0031347 233 0.013
organic acid transport GO:0015849 101 0.013
meiotic cell cycle process GO:1903046 77 0.013
sequestering of metal ion GO:0051238 19 0.013
skeletal system development GO:0001501 356 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
positive regulation of potassium ion transport GO:0043268 3 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
hormone secretion GO:0046879 128 0.013
intracellular protein transport GO:0006886 204 0.013
metanephric glomerulus development GO:0072224 13 0.013
innate immune response GO:0045087 157 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
eye photoreceptor cell differentiation GO:0001754 41 0.013
chromatin modification GO:0016568 187 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
body fluid secretion GO:0007589 53 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
leukocyte differentiation GO:0002521 342 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
ceramide metabolic process GO:0006672 31 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
leukocyte migration GO:0050900 124 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
developmental maturation GO:0021700 193 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
cellular chemical homeostasis GO:0055082 215 0.012
regulation of peptide hormone secretion GO:0090276 75 0.012
stem cell differentiation GO:0048863 268 0.012
nucleotide catabolic process GO:0009166 217 0.012
regulation of mapk cascade GO:0043408 248 0.012
exocytosis GO:0006887 121 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
morphogenesis of a polarized epithelium GO:0001738 37 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
detection of molecule of bacterial origin GO:0032490 2 0.012
regulation of protein catabolic process GO:0042176 108 0.012
insulin secretion GO:0030073 89 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
tissue homeostasis GO:0001894 115 0.012
response to acid chemical GO:0001101 111 0.012
coagulation GO:0050817 78 0.012
regulation of hormone levels GO:0010817 211 0.012
membrane lipid biosynthetic process GO:0046467 32 0.012
progesterone metabolic process GO:0042448 4 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
alcohol metabolic process GO:0006066 116 0.011
negative regulation of molecular function GO:0044092 258 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of peptide secretion GO:0002791 77 0.011
carboxylic acid transport GO:0046942 100 0.011
plasma membrane organization GO:0007009 90 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
cholesterol efflux GO:0033344 24 0.011
innate immune response in mucosa GO:0002227 3 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
cation homeostasis GO:0055080 212 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
digestive system development GO:0055123 200 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
organelle localization GO:0051640 179 0.011
alpha amino acid biosynthetic process GO:1901607 15 0.011
divalent inorganic cation transport GO:0072511 178 0.011
carbohydrate homeostasis GO:0033500 128 0.011
cellular protein catabolic process GO:0044257 155 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
icosanoid metabolic process GO:0006690 33 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
protein localization to nucleus GO:0034504 121 0.011
cell maturation GO:0048469 127 0.010
posttranscriptional regulation of gene expression GO:0010608 155 0.010
organelle assembly GO:0070925 177 0.010
fatty acid biosynthetic process GO:0006633 41 0.010
rna interference GO:0016246 2 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
inorganic anion transport GO:0015698 43 0.010
cell type specific apoptotic process GO:0097285 268 0.010
dna metabolic process GO:0006259 303 0.010
anatomical structure homeostasis GO:0060249 145 0.010
atp catabolic process GO:0006200 55 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
myeloid cell homeostasis GO:0002262 114 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
retina development in camera type eye GO:0060041 119 0.010
astrocyte fate commitment GO:0060018 4 0.010
oligopeptide transmembrane transport GO:0035672 4 0.010
regulation of proteolysis GO:0030162 164 0.010
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.010
protein localization to organelle GO:0033365 185 0.010
organophosphate catabolic process GO:0046434 232 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
activation of immune response GO:0002253 138 0.010
rho protein signal transduction GO:0007266 32 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
epithelial cell development GO:0002064 159 0.010

Klk1b9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
disease of metabolism DOID:0014667 0 0.012
immune system disease DOID:2914 0 0.012
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
bone disease DOID:0080001 0 0.011