Mus musculus

0 known processes

Aifm2

apoptosis-inducing factor, mitochondrion-associated 2

(Aliases: Amid,5430437E11Rik,PRG3,D730001I10Rik)

Aifm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 323 0.130
oxidation reduction process GO:0055114 342 0.104
cellular amino acid metabolic process GO:0006520 103 0.075
lipid biosynthetic process GO:0008610 179 0.064
glycerolipid metabolic process GO:0046486 122 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.058
small molecule catabolic process GO:0044282 71 0.057
cellular ketone metabolic process GO:0042180 84 0.057
cation transport GO:0006812 399 0.049
fatty acid metabolic process GO:0006631 121 0.047
cellular amine metabolic process GO:0044106 44 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
amine metabolic process GO:0009308 45 0.044
carbohydrate metabolic process GO:0005975 230 0.044
nucleobase containing small molecule metabolic process GO:0055086 352 0.042
nitrogen compound transport GO:0071705 271 0.040
aromatic compound catabolic process GO:0019439 286 0.040
regulation of cellular amine metabolic process GO:0033238 20 0.039
monocarboxylic acid metabolic process GO:0032787 191 0.038
coenzyme metabolic process GO:0006732 52 0.038
lipid modification GO:0030258 65 0.038
sulfur compound metabolic process GO:0006790 100 0.038
nucleotide metabolic process GO:0009117 332 0.038
organic acid catabolic process GO:0016054 51 0.036
transmembrane transport GO:0055085 412 0.035
apoptotic signaling pathway GO:0097190 306 0.034
cofactor metabolic process GO:0051186 80 0.032
regulation of cytokine production GO:0001817 266 0.032
regulation of fatty acid oxidation GO:0046320 10 0.032
heterocycle catabolic process GO:0046700 280 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.031
mitochondrion organization GO:0007005 134 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
regulation of membrane potential GO:0042391 192 0.028
glycerolipid biosynthetic process GO:0045017 50 0.028
ion transmembrane transport GO:0034220 361 0.028
cellular lipid catabolic process GO:0044242 52 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
anion transport GO:0006820 177 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
positive regulation of protein modification process GO:0031401 299 0.028
organic acid transport GO:0015849 101 0.027
membrane organization GO:0061024 245 0.027
cytokine production GO:0001816 319 0.027
organic anion transport GO:0015711 137 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
negative regulation of molecular function GO:0044092 258 0.025
purine containing compound metabolic process GO:0072521 311 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
acylglycerol metabolic process GO:0006639 55 0.025
neutral lipid metabolic process GO:0006638 57 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regulation of hormone levels GO:0010817 211 0.024
regulation of secretion GO:0051046 274 0.024
positive regulation of cell death GO:0010942 224 0.023
regulation of defense response GO:0031347 233 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
response to organonitrogen compound GO:0010243 246 0.023
organophosphate biosynthetic process GO:0090407 122 0.023
carboxylic acid transport GO:0046942 100 0.023
intracellular protein transport GO:0006886 204 0.023
cellular homeostasis GO:0019725 240 0.022
spermatogenesis GO:0007283 284 0.022
macromolecule catabolic process GO:0009057 281 0.022
cellular chemical homeostasis GO:0055082 215 0.022
regulation of lipid metabolic process GO:0019216 118 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
monosaccharide metabolic process GO:0005996 106 0.022
endomembrane system organization GO:0010256 147 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
cytoplasmic transport GO:0016482 234 0.022
glycosyl compound metabolic process GO:1901657 246 0.021
reactive nitrogen species metabolic process GO:2001057 0 0.021
regulation of organelle organization GO:0033043 289 0.021
ras protein signal transduction GO:0007265 77 0.021
regulation of hydrolase activity GO:0051336 246 0.021
peptidyl amino acid modification GO:0018193 336 0.021
carboxylic acid catabolic process GO:0046395 51 0.021
triglyceride metabolic process GO:0006641 51 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.020
response to oxidative stress GO:0006979 123 0.020
cellular response to lipid GO:0071396 145 0.020
actin cytoskeleton organization GO:0030036 220 0.020
leukocyte differentiation GO:0002521 342 0.020
regulation of kinase activity GO:0043549 249 0.020
lipid catabolic process GO:0016042 69 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
amide transport GO:0042886 138 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
nucleoside metabolic process GO:0009116 246 0.020
lipid localization GO:0010876 126 0.020
protein localization to organelle GO:0033365 185 0.020
acylglycerol biosynthetic process GO:0046463 18 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.019
fat cell differentiation GO:0045444 160 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
synaptic transmission GO:0007268 329 0.019
response to organic cyclic compound GO:0014070 198 0.019
cation transmembrane transport GO:0098655 266 0.019
innate immune response GO:0045087 157 0.019
immune effector process GO:0002252 321 0.019
male gamete generation GO:0048232 285 0.019
maintenance of location GO:0051235 89 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
skeletal system development GO:0001501 356 0.019
positive regulation of sequestering of triglyceride GO:0010890 4 0.019
nucleotide catabolic process GO:0009166 217 0.019
ribonucleoside metabolic process GO:0009119 245 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
regulation of proteolysis GO:0030162 164 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
lipid transport GO:0006869 98 0.018
t cell activation GO:0042110 289 0.018
small molecule biosynthetic process GO:0044283 132 0.018
microtubule based process GO:0007017 236 0.017
regulation of cell cycle GO:0051726 281 0.017
alcohol metabolic process GO:0006066 116 0.017
peptide transport GO:0015833 133 0.017
inflammatory response GO:0006954 244 0.017
response to acid chemical GO:0001101 111 0.017
cell adhesion GO:0007155 329 0.017
cell type specific apoptotic process GO:0097285 268 0.017
carbohydrate catabolic process GO:0016052 32 0.017
organelle localization GO:0051640 179 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
lipid oxidation GO:0034440 29 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
hormone secretion GO:0046879 128 0.016
protein maturation GO:0051604 176 0.016
regulation of secretion by cell GO:1903530 249 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
thioester metabolic process GO:0035383 19 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
dna metabolic process GO:0006259 303 0.016
protein ubiquitination GO:0016567 171 0.016
organelle fission GO:0048285 170 0.016
dephosphorylation GO:0016311 129 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
positive regulation of programmed cell death GO:0043068 218 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
multicellular organism growth GO:0035264 161 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
endocytosis GO:0006897 168 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
response to peptide hormone GO:0043434 127 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
carbohydrate homeostasis GO:0033500 128 0.015
glucose metabolic process GO:0006006 92 0.015
germ cell development GO:0007281 185 0.015
lateral inhibition GO:0046331 1 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
protein targeting GO:0006605 143 0.015
response to peptide GO:1901652 136 0.015
organophosphate catabolic process GO:0046434 232 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
nucleoside catabolic process GO:0009164 206 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
action potential GO:0001508 78 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
cation homeostasis GO:0055080 212 0.015
positive regulation of fatty acid oxidation GO:0046321 4 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
regulation of cell activation GO:0050865 289 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
response to lipopolysaccharide GO:0032496 128 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
response to extracellular stimulus GO:0009991 127 0.014
cellular response to acid chemical GO:0071229 68 0.014
regulation of fatty acid metabolic process GO:0019217 28 0.014
regulation of protein transport GO:0051223 163 0.014
triglyceride biosynthetic process GO:0019432 17 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
negative regulation of fatty acid metabolic process GO:0045922 10 0.014
protein oligomerization GO:0051259 67 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
monocarboxylic acid catabolic process GO:0072329 27 0.014
peptide secretion GO:0002790 114 0.014
organic acid biosynthetic process GO:0016053 86 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
protein catabolic process GO:0030163 221 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
fatty acid transmembrane transport GO:1902001 1 0.014
defense response to other organism GO:0098542 197 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
regulation of cell migration GO:0030334 219 0.014
regulation of intracellular transport GO:0032386 159 0.014
regulation of transferase activity GO:0051338 263 0.014
axonogenesis GO:0007409 274 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
protein processing GO:0016485 163 0.014
negative regulation of protein modification process GO:0031400 163 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
fatty acid oxidation GO:0019395 28 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
nuclear transport GO:0051169 139 0.013
anion transmembrane transport GO:0098656 71 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
regulation of anatomical structure size GO:0090066 178 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
sterol homeostasis GO:0055092 45 0.013
regulation of response to wounding GO:1903034 189 0.013
regulation of ion transport GO:0043269 215 0.013
divalent metal ion transport GO:0070838 172 0.013
cellular modified amino acid metabolic process GO:0006575 63 0.013
cellular ion homeostasis GO:0006873 165 0.013
neuronal action potential GO:0019228 54 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
sensory perception GO:0007600 245 0.013
transmission of nerve impulse GO:0019226 76 0.013
regulation of cellular response to stress GO:0080135 159 0.013
negative regulation of immune system process GO:0002683 209 0.013
mapk cascade GO:0000165 281 0.013
chemotaxis GO:0006935 247 0.013
cellular amide metabolic process GO:0043603 58 0.013
gland development GO:0048732 330 0.013
regulation of cell motility GO:2000145 236 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
rho protein signal transduction GO:0007266 32 0.013
regulation of mapk cascade GO:0043408 248 0.013
regulation of inflammatory response GO:0050727 147 0.013
regulation of multi organism process GO:0043900 111 0.013
positive regulation of nervous system development GO:0051962 221 0.013
response to inorganic substance GO:0010035 96 0.013
cholesterol metabolic process GO:0008203 56 0.013
myeloid cell differentiation GO:0030099 233 0.013
developmental maturation GO:0021700 193 0.013
regulation of innate immune response GO:0045088 91 0.013
homeostasis of number of cells GO:0048872 210 0.012
purine containing compound catabolic process GO:0072523 213 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
divalent inorganic cation transport GO:0072511 178 0.012
monocarboxylic acid transport GO:0015718 44 0.012
anatomical structure homeostasis GO:0060249 145 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
hexose metabolic process GO:0019318 98 0.012
muscle cell differentiation GO:0042692 261 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
sterol metabolic process GO:0016125 58 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
positive regulation of cell development GO:0010720 237 0.012
regulation of protein localization GO:0032880 231 0.012
fatty acid catabolic process GO:0009062 25 0.012
regulation of neuron differentiation GO:0045664 281 0.012
lymphocyte differentiation GO:0030098 242 0.012
response to nutrient levels GO:0031667 109 0.012
positive regulation of kinase activity GO:0033674 155 0.012
neuron death GO:0070997 154 0.012
response to radiation GO:0009314 165 0.012
multicellular organismal signaling GO:0035637 91 0.012
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
regulation of peptide secretion GO:0002791 77 0.012
metal ion homeostasis GO:0055065 189 0.012
regulation of protein kinase activity GO:0045859 232 0.012
locomotory behavior GO:0007626 195 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
renal system development GO:0072001 225 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
positive regulation of secretion GO:0051047 130 0.011
forebrain development GO:0030900 302 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
cell substrate adhesion GO:0031589 130 0.011
regulation of homeostatic process GO:0032844 182 0.011
tissue homeostasis GO:0001894 115 0.011
phospholipid metabolic process GO:0006644 87 0.011
very long chain fatty acid catabolic process GO:0042760 2 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
organic hydroxy compound transport GO:0015850 93 0.011
spermatid development GO:0007286 108 0.011
cellular protein complex assembly GO:0043623 116 0.011
positive regulation of transferase activity GO:0051347 167 0.011
regulation of fatty acid beta oxidation GO:0031998 1 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
regulation of feeding behavior GO:0060259 3 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
epithelial cell development GO:0002064 159 0.011
glucose homeostasis GO:0042593 128 0.011
striated muscle tissue development GO:0014706 293 0.011
positive regulation of innate immune response GO:0045089 80 0.011
positive regulation of organelle organization GO:0010638 128 0.011
adult behavior GO:0030534 135 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
camera type eye development GO:0043010 266 0.011
response to oxygen levels GO:0070482 62 0.011
nuclear division GO:0000280 158 0.011
peptide hormone secretion GO:0030072 109 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
fatty acid biosynthetic process GO:0006633 41 0.011
spermatid differentiation GO:0048515 115 0.011
regulation of lipid biosynthetic process GO:0046890 54 0.011
regulation of t cell activation GO:0050863 170 0.011
chromatin organization GO:0006325 206 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
cell chemotaxis GO:0060326 81 0.011
response to monosaccharide GO:0034284 67 0.011
peptide metabolic process GO:0006518 46 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
rna interference GO:0016246 2 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
blood vessel morphogenesis GO:0048514 285 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
lipid homeostasis GO:0055088 63 0.010
acyl coa metabolic process GO:0006637 19 0.010
calcium ion transport GO:0006816 159 0.010
regulation of ras protein signal transduction GO:0046578 114 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
regulation of hormone secretion GO:0046883 88 0.010
regulation of cell projection organization GO:0031344 206 0.010
regulation of peptidase activity GO:0052547 96 0.010
positive regulation of defense response GO:0031349 124 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
vesicle organization GO:0016050 60 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
leukocyte migration GO:0050900 124 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
neutral lipid biosynthetic process GO:0046460 18 0.010
negative regulation of lipid metabolic process GO:0045833 30 0.010
leukocyte proliferation GO:0070661 172 0.010
amino acid transmembrane transport GO:0003333 37 0.010

Aifm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
disease of metabolism DOID:0014667 0 0.027
central nervous system disease DOID:331 0 0.017
inherited metabolic disorder DOID:655 0 0.015
sensory system disease DOID:0050155 0 0.013
immune system disease DOID:2914 0 0.013
organ system cancer DOID:0050686 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
bone disease DOID:0080001 0 0.012
musculoskeletal system disease DOID:17 0 0.012
bone development disease DOID:0080006 0 0.012
connective tissue disease DOID:65 0 0.012