Mus musculus

30 known processes

Nprl3

nitrogen permease regulator-like 3 (S. cerevisiae)

(Aliases: Mare,Aag,m(alpha)RE,HS-40,Phg,HS-26,CGTHBA,Prox1)

Nprl3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 66 0.136
cellular ketone metabolic process GO:0042180 84 0.107
cellular amino acid metabolic process GO:0006520 103 0.095
cell junction maintenance GO:0034331 4 0.094
regulation of cellular amine metabolic process GO:0033238 20 0.089
cellular amine metabolic process GO:0044106 44 0.084
cellular response to arsenic containing substance GO:0071243 4 0.083
ras protein signal transduction GO:0007265 77 0.083
regulation of cellular amino acid metabolic process GO:0006521 5 0.080
cellular nitrogen compound catabolic process GO:0044270 280 0.071
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.065
aromatic compound catabolic process GO:0019439 286 0.061
macromolecule catabolic process GO:0009057 281 0.060
cellular response to cadmium ion GO:0071276 3 0.056
cellular response to dna damage stimulus GO:0006974 207 0.056
amine metabolic process GO:0009308 45 0.056
carbohydrate derivative catabolic process GO:1901136 231 0.054
organic cyclic compound catabolic process GO:1901361 295 0.053
carbohydrate derivative biosynthetic process GO:1901137 183 0.049
organophosphate catabolic process GO:0046434 232 0.049
organonitrogen compound catabolic process GO:1901565 264 0.049
heterocycle catabolic process GO:0046700 280 0.048
organonitrogen compound biosynthetic process GO:1901566 192 0.047
small gtpase mediated signal transduction GO:0007264 97 0.046
nucleoside triphosphate metabolic process GO:0009141 230 0.046
skeletal system development GO:0001501 356 0.045
ribose phosphate metabolic process GO:0019693 291 0.040
nucleotide catabolic process GO:0009166 217 0.038
protein catabolic process GO:0030163 221 0.038
cellular response to cytokine stimulus GO:0071345 189 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
transmembrane transport GO:0055085 412 0.037
ribonucleoside catabolic process GO:0042454 206 0.036
regulation of ras protein signal transduction GO:0046578 114 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
glycosyl compound metabolic process GO:1901657 246 0.036
purine containing compound metabolic process GO:0072521 311 0.035
regulation of response to drug GO:2001023 2 0.034
nucleotide metabolic process GO:0009117 332 0.033
ribonucleoside metabolic process GO:0009119 245 0.033
negative regulation of phosphorus metabolic process GO:0010563 184 0.032
positive regulation of protein export from nucleus GO:0046827 4 0.031
nucleoside metabolic process GO:0009116 246 0.031
apoptotic signaling pathway GO:0097190 306 0.031
positive regulation of protein phosphorylation GO:0001934 242 0.031
guanosine containing compound catabolic process GO:1901069 144 0.031
negative regulation of phosphate metabolic process GO:0045936 184 0.031
regulation of protein localization GO:0032880 231 0.031
peptidyl amino acid modification GO:0018193 336 0.029
ribonucleotide catabolic process GO:0009261 208 0.029
negative regulation of transposition GO:0010529 2 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
response to epidermal growth factor GO:0070849 4 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
purine containing compound catabolic process GO:0072523 213 0.027
cellular response to biotic stimulus GO:0071216 92 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
nitrogen compound transport GO:0071705 271 0.026
response to lipopolysaccharide GO:0032496 128 0.026
glycoprotein biosynthetic process GO:0009101 89 0.026
regulation of organelle organization GO:0033043 289 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
synaptic transmission GO:0007268 329 0.026
sensory perception GO:0007600 245 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
mapk cascade GO:0000165 281 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
guanosine containing compound metabolic process GO:1901068 144 0.025
response to organonitrogen compound GO:0010243 246 0.025
regulation of protein transport GO:0051223 163 0.025
cellular response to lipopolysaccharide GO:0071222 77 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
nuclear transport GO:0051169 139 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
cellular response to molecule of bacterial origin GO:0071219 83 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
connective tissue development GO:0061448 179 0.024
cytokine mediated signaling pathway GO:0019221 115 0.024
nucleoside catabolic process GO:0009164 206 0.024
cellular homeostasis GO:0019725 240 0.024
negative regulation of phosphorylation GO:0042326 166 0.024
pyrimidine containing compound metabolic process GO:0072527 11 0.023
regulation of mapk cascade GO:0043408 248 0.023
positive regulation of protein modification process GO:0031401 299 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
cytoplasmic transport GO:0016482 234 0.023
cellular response to lipid GO:0071396 145 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
dna metabolic process GO:0006259 303 0.023
carbohydrate metabolic process GO:0005975 230 0.023
cation transport GO:0006812 399 0.023
regulation of transposition GO:0010528 2 0.023
chromatin organization GO:0006325 206 0.022
response to nutrient levels GO:0031667 109 0.022
negative regulation of cell cycle GO:0045786 123 0.022
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.022
regulation of translation GO:0006417 71 0.022
activation of immune response GO:0002253 138 0.022
glycoprotein metabolic process GO:0009100 116 0.022
anion transport GO:0006820 177 0.022
cation transmembrane transport GO:0098655 266 0.021
histone modification GO:0016570 159 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
gland development GO:0048732 330 0.021
photoreceptor cell differentiation GO:0046530 52 0.021
rho protein signal transduction GO:0007266 32 0.021
regulation of cell cycle GO:0051726 281 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
response to growth factor GO:0070848 198 0.020
protein targeting GO:0006605 143 0.020
mitotic cell cycle GO:0000278 195 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
oxidation reduction process GO:0055114 342 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
fatty acid metabolic process GO:0006631 121 0.020
cellular lipid metabolic process GO:0044255 323 0.020
cell type specific apoptotic process GO:0097285 268 0.020
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.020
adherens junction maintenance GO:0034334 1 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
single organism nuclear import GO:1902593 95 0.019
response to starvation GO:0042594 65 0.019
translation GO:0006412 93 0.018
peptidyl tyrosine phosphorylation GO:0018108 143 0.018
peptide transport GO:0015833 133 0.018
cell cycle switching GO:0060184 1 0.018
rab protein signal transduction GO:0032482 1 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
chromatin modification GO:0016568 187 0.018
inflammatory response GO:0006954 244 0.018
negative regulation of molecular function GO:0044092 258 0.018
regulation of secretion by cell GO:1903530 249 0.018
intracellular protein transport GO:0006886 204 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
response to organic cyclic compound GO:0014070 198 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
nuclear division GO:0000280 158 0.017
ion transmembrane transport GO:0034220 361 0.017
protein localization to organelle GO:0033365 185 0.017
pyrimidine nucleobase metabolic process GO:0006206 3 0.017
gtp catabolic process GO:0006184 143 0.016
regulation of response to wounding GO:1903034 189 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
positive regulation of cell death GO:0010942 224 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
myeloid cell differentiation GO:0030099 233 0.016
positive regulation of organelle organization GO:0010638 128 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
organelle fission GO:0048285 170 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
response to extracellular stimulus GO:0009991 127 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.015
covalent chromatin modification GO:0016569 163 0.015
mitotic cell cycle process GO:1903047 159 0.015
dna repair GO:0006281 107 0.015
positive regulation of tor signaling GO:0032008 3 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
macroautophagy GO:0016236 21 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
cellular response to starvation GO:0009267 57 0.015
immune response activating signal transduction GO:0002757 116 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
nuclear import GO:0051170 95 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
cellular response to inorganic substance GO:0071241 37 0.014
regulation of cellular response to stress GO:0080135 159 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
adult behavior GO:0030534 135 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
protein import GO:0017038 101 0.014
cellular response to nutrient levels GO:0031669 64 0.014
developmental maturation GO:0021700 193 0.014
microtubule based process GO:0007017 236 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
cation homeostasis GO:0055080 212 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
peptidyl serine modification GO:0018209 83 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
cytokine production GO:0001816 319 0.014
protein export from nucleus GO:0006611 20 0.014
regulation of intracellular transport GO:0032386 159 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
response to inorganic substance GO:0010035 96 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
negative regulation of mapk cascade GO:0043409 65 0.013
locomotory behavior GO:0007626 195 0.013
membrane organization GO:0061024 245 0.013
embryonic limb morphogenesis GO:0030326 126 0.013
regulation of meiotic cell cycle GO:0051445 34 0.013
compound eye development GO:0048749 1 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
organic acid biosynthetic process GO:0016053 86 0.013
positive regulation of protein transport GO:0051222 93 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
jnk cascade GO:0007254 72 0.013
immune effector process GO:0002252 321 0.013
mitotic nuclear division GO:0007067 48 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
regulation of cell cycle process GO:0010564 160 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
regionalization GO:0003002 337 0.013
rna processing GO:0006396 105 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.012
regulation of membrane potential GO:0042391 192 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
protein acylation GO:0043543 64 0.012
cartilage development GO:0051216 140 0.012
positive regulation of nervous system development GO:0051962 221 0.012
regulation of transferase activity GO:0051338 263 0.012
amide transport GO:0042886 138 0.012
cellular ion homeostasis GO:0006873 165 0.012
nuclear export GO:0051168 34 0.012
homeostasis of number of cells GO:0048872 210 0.012
immune response regulating signaling pathway GO:0002764 125 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
cilium morphogenesis GO:0060271 102 0.012
carbohydrate homeostasis GO:0033500 128 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
regulation of ion transport GO:0043269 215 0.012
sulfur compound metabolic process GO:0006790 100 0.012
regulation of cytokine production GO:0001817 266 0.012
wnt signaling pathway GO:0016055 188 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
organic anion transport GO:0015711 137 0.012
response to oxidative stress GO:0006979 123 0.012
negative regulation of cellular catabolic process GO:0031330 47 0.012
lipid biosynthetic process GO:0008610 179 0.012
organelle assembly GO:0070925 177 0.011
actin cytoskeleton organization GO:0030036 220 0.011
positive regulation of gtpase activity GO:0043547 85 0.011
cellular response to external stimulus GO:0071496 88 0.011
protein glycosylation GO:0006486 55 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
regulation of chromosome organization GO:0033044 83 0.011
sequestering of metal ion GO:0051238 19 0.011
response to peptide hormone GO:0043434 127 0.011
negative regulation of immune system process GO:0002683 209 0.011
regulation of defense response GO:0031347 233 0.011
negative regulation of dna replication GO:0008156 4 0.011
male gamete generation GO:0048232 285 0.011
wound healing GO:0042060 157 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
regulation of macroautophagy GO:0016241 12 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
regulation of binding GO:0051098 111 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
glucose homeostasis GO:0042593 128 0.011
extracellular structure organization GO:0043062 148 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
response to drug GO:0042493 75 0.011
meiotic cell cycle GO:0051321 122 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
neuron death GO:0070997 154 0.011
extracellular matrix organization GO:0030198 147 0.011
cell maturation GO:0048469 127 0.011
cellularization GO:0007349 1 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
glycosylation GO:0070085 62 0.011
placenta development GO:0001890 140 0.011
leukocyte differentiation GO:0002521 342 0.011
rna interference GO:0016246 2 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
cellular chemical homeostasis GO:0055082 215 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
t cell receptor signaling pathway GO:0050852 46 0.010
divalent metal ion transport GO:0070838 172 0.010
bone development GO:0060348 120 0.010
multicellular organism growth GO:0035264 161 0.010
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.010
skeletal system morphogenesis GO:0048705 203 0.010
cognition GO:0050890 149 0.010
development of primary sexual characteristics GO:0045137 143 0.010
negative regulation of macroautophagy GO:0016242 5 0.010
cell junction organization GO:0034330 77 0.010
protein processing GO:0016485 163 0.010
carboxylic acid transport GO:0046942 100 0.010
regulation of neuron differentiation GO:0045664 281 0.010
regulation of ras gtpase activity GO:0032318 88 0.010
innate immune response GO:0045087 157 0.010

Nprl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.046
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.042
hematopoietic system disease DOID:74 0 0.033
musculoskeletal system disease DOID:17 0 0.021
muscular disease DOID:0080000 0 0.017
myopathy DOID:423 0 0.017
muscle tissue disease DOID:66 0 0.017
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
anemia DOID:2355 0 0.013
central nervous system disease DOID:331 0 0.012
neuropathy DOID:870 0 0.011
neuromuscular disease DOID:440 0 0.011
inherited metabolic disorder DOID:655 0 0.010
disease of metabolism DOID:0014667 0 0.010