Mus musculus

0 known processes

Prl2a1

prolactin family 2, subfamily a, member 1

(Aliases: Prlpm,PLP-M)

Prl2a1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of microvillus organization GO:0032530 3 0.492
Mouse
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.432
Mouse
regulation of microvillus assembly GO:0032534 3 0.382
Mouse
striated muscle tissue development GO:0014706 293 0.267
Mouse
negative regulation of endothelial cell migration GO:0010596 4 0.245
Mouse
regulation of cell projection organization GO:0031344 206 0.146
Mouse
stem cell proliferation GO:0072089 117 0.138
Mouse
muscle cell differentiation GO:0042692 261 0.130
Mouse
skeletal muscle fiber development GO:0048741 58 0.126
Mouse
myotube cell development GO:0014904 60 0.106
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.098
macromolecule catabolic process GO:0009057 281 0.085
muscle cell development GO:0055001 133 0.078
Mouse
regulation of cell motility GO:2000145 236 0.078
Mouse
amine metabolic process GO:0009308 45 0.072
regulation of myotube differentiation GO:0010830 62 0.067
Mouse
negative regulation of myoblast differentiation GO:0045662 18 0.062
Mouse
protein catabolic process GO:0030163 221 0.061
regulation of skeletal muscle fiber development GO:0048742 36 0.054
Mouse
negative regulation of muscle cell differentiation GO:0051148 33 0.053
Mouse
positive regulation of cell projection organization GO:0031346 95 0.053
Mouse
positive regulation of cell development GO:0010720 237 0.051
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.049
regulation of transferase activity GO:0051338 263 0.046
regulation of cell migration GO:0030334 219 0.045
Mouse
muscle fiber development GO:0048747 76 0.045
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.045
skeletal muscle organ development GO:0060538 163 0.044
Mouse
embryonic organ morphogenesis GO:0048562 276 0.044
muscle tissue development GO:0060537 308 0.044
Mouse
positive regulation of protein modification process GO:0031401 299 0.043
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.043
negative regulation of cell migration GO:0030336 59 0.043
Mouse
striated muscle cell development GO:0055002 125 0.041
Mouse
synaptic transmission GO:0007268 329 0.040
regulation of striated muscle cell differentiation GO:0051153 81 0.040
Mouse
blood vessel morphogenesis GO:0048514 285 0.039
Mouse
cellular ketone metabolic process GO:0042180 84 0.039
regulation of cell activation GO:0050865 289 0.038
nitrogen compound transport GO:0071705 271 0.038
regulation of cellular component biogenesis GO:0044087 181 0.038
Mouse
sensory perception GO:0007600 245 0.037
negative regulation of cell motility GO:2000146 61 0.037
Mouse
regulation of protein kinase activity GO:0045859 232 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.035
cellular amine metabolic process GO:0044106 44 0.035
regulation of stem cell proliferation GO:0072091 78 0.035
Mouse
cellular amino acid metabolic process GO:0006520 103 0.035
negative regulation of intracellular signal transduction GO:1902532 167 0.035
leukocyte migration GO:0050900 124 0.034
positive regulation of cell migration GO:0030335 109 0.034
Mouse
ameboidal type cell migration GO:0001667 128 0.034
Mouse
myotube differentiation GO:0014902 105 0.033
Mouse
response to lipopolysaccharide GO:0032496 128 0.033
regulation of system process GO:0044057 200 0.031
regulation of muscle tissue development GO:1901861 97 0.031
Mouse
positive regulation of cell motility GO:2000147 116 0.030
Mouse
immune effector process GO:0002252 321 0.030
cellular response to organonitrogen compound GO:0071417 145 0.029
cation transmembrane transport GO:0098655 266 0.029
camera type eye development GO:0043010 266 0.029
ion transmembrane transport GO:0034220 361 0.028
regulation of neuron differentiation GO:0045664 281 0.028
response to growth factor GO:0070848 198 0.028
axonogenesis GO:0007409 274 0.028
regulation of cell projection assembly GO:0060491 38 0.028
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.028
response to oxidative stress GO:0006979 123 0.027
inflammatory response GO:0006954 244 0.026
regulation of lymphocyte activation GO:0051249 240 0.026
regulation of kinase activity GO:0043549 249 0.026
sensory perception of sound GO:0007605 97 0.026
sensory perception of mechanical stimulus GO:0050954 107 0.026
sulfur compound metabolic process GO:0006790 100 0.025
cellular homeostasis GO:0019725 240 0.025
muscle contraction GO:0006936 101 0.025
epidermis development GO:0008544 187 0.025
cytokine production GO:0001816 319 0.025
cation transport GO:0006812 399 0.024
eosinophil migration GO:0072677 3 0.024
regulation of action potential GO:0098900 4 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
anion transport GO:0006820 177 0.024
tissue migration GO:0090130 68 0.023
Mouse
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
protein processing GO:0016485 163 0.023
regulation of vasculature development GO:1901342 88 0.023
Mouse
nucleotide metabolic process GO:0009117 332 0.022
positive regulation of cell activation GO:0050867 158 0.022
skin development GO:0043588 220 0.022
mapk cascade GO:0000165 281 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
positive regulation of protein kinase activity GO:0045860 144 0.022
chondroitin sulfate metabolic process GO:0030204 17 0.022
regulation of cell cycle GO:0051726 281 0.022
response to organonitrogen compound GO:0010243 246 0.021
myoblast differentiation GO:0045445 52 0.021
Mouse
negative regulation of vasculature development GO:1901343 26 0.021
Mouse
regulation of b cell activation GO:0050864 81 0.021
epithelium migration GO:0090132 63 0.021
Mouse
endothelial cell migration GO:0043542 44 0.021
Mouse
small molecule biosynthetic process GO:0044283 132 0.021
apoptotic signaling pathway GO:0097190 306 0.021
negative regulation of cytokine production GO:0001818 84 0.020
negative regulation of cell development GO:0010721 169 0.020
epithelial cell migration GO:0010631 63 0.020
Mouse
positive regulation of neuroblast proliferation GO:0002052 19 0.020
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 42 0.020
Mouse
ossification GO:0001503 216 0.020
multicellular organismal homeostasis GO:0048871 164 0.020
cellular response to insulin stimulus GO:0032869 78 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
purine containing compound catabolic process GO:0072523 213 0.019
response to organic cyclic compound GO:0014070 198 0.019
heart process GO:0003015 94 0.019
acetylcholine secretion neurotransmission GO:0014055 2 0.019
negative regulation of epithelial cell migration GO:0010633 9 0.019
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.019
intracellular protein transport GO:0006886 204 0.019
cofactor metabolic process GO:0051186 80 0.019
chemotaxis GO:0006935 247 0.019
positive regulation of endothelial cell migration GO:0010595 12 0.019
Mouse
negative regulation of cellular component organization GO:0051129 194 0.019
action potential GO:0001508 78 0.018
positive regulation of angiogenesis GO:0045766 46 0.018
Mouse
cellular response to hormone stimulus GO:0032870 150 0.018
negative regulation of angiogenesis GO:0016525 25 0.018
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.018
regulation of membrane potential GO:0042391 192 0.018
sensory organ morphogenesis GO:0090596 242 0.018
regulation of blood vessel endothelial cell migration GO:0043535 12 0.018
Mouse
regulation of multi organism process GO:0043900 111 0.018
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
peptidyl amino acid modification GO:0018193 336 0.018
wnt signaling pathway GO:0016055 188 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
response to insulin GO:0032868 100 0.017
neuroblast proliferation GO:0007405 49 0.017
Mouse
positive regulation of catecholamine secretion GO:0033605 2 0.017
membrane organization GO:0061024 245 0.017
purine containing compound metabolic process GO:0072521 311 0.017
cellular protein complex assembly GO:0043623 116 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
regulation of circadian sleep wake cycle GO:0042749 3 0.017
regulation of neuron projection development GO:0010975 169 0.017
neuron projection guidance GO:0097485 141 0.017
lymphocyte differentiation GO:0030098 242 0.017
neural precursor cell proliferation GO:0061351 121 0.017
Mouse
response to radiation GO:0009314 165 0.017
regulation of cellular ketone metabolic process GO:0010565 66 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
spermatogenesis GO:0007283 284 0.016
muscle system process GO:0003012 141 0.016
transforming growth factor beta secretion GO:0038044 1 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
cellular response to peptide GO:1901653 92 0.016
t cell activation GO:0042110 289 0.016
regulation of organelle organization GO:0033043 289 0.016
leukocyte differentiation GO:0002521 342 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
regulation of defense response GO:0031347 233 0.016
cellular protein catabolic process GO:0044257 155 0.016
synaptic transmission involved in micturition GO:0060084 3 0.016
transmembrane transport GO:0055085 412 0.016
ras protein signal transduction GO:0007265 77 0.016
cellular ion homeostasis GO:0006873 165 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
response to acid chemical GO:0001101 111 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
regulation of mapk cascade GO:0043408 248 0.016
reactive oxygen species metabolic process GO:0072593 84 0.015
protein localization to organelle GO:0033365 185 0.015
respiratory gaseous exchange GO:0007585 43 0.015
response to peptide GO:1901652 136 0.015
response to hypoxia GO:0001666 58 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
regulation of ion transport GO:0043269 215 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
regulation of epithelial cell migration GO:0010632 35 0.015
Mouse
regulation of proteolysis GO:0030162 164 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
positive regulation of defense response GO:0031349 124 0.015
positive regulation of stem cell proliferation GO:2000648 59 0.015
Mouse
response to peptide hormone GO:0043434 127 0.015
learning GO:0007612 98 0.015
negative regulation of molecular function GO:0044092 258 0.015
organic hydroxy compound biosynthetic process GO:1901617 77 0.015
nucleotide catabolic process GO:0009166 217 0.014
regulation of secretion GO:0051046 274 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
regulation of protein catabolic process GO:0042176 108 0.014
gland development GO:0048732 330 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
innate immune response GO:0045087 157 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
positive regulation of nervous system development GO:0051962 221 0.014
Mouse
pigmentation GO:0043473 71 0.014
detection of abiotic stimulus GO:0009582 60 0.014
protein maturation GO:0051604 176 0.014
multi multicellular organism process GO:0044706 109 0.014
positive regulation of protein catabolic process GO:0045732 60 0.014
regulation of myoblast differentiation GO:0045661 29 0.014
Mouse
b cell activation GO:0042113 161 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
microtubule based process GO:0007017 236 0.014
regulation of neuron death GO:1901214 134 0.014
chromatin organization GO:0006325 206 0.014
positive regulation of dopamine secretion GO:0033603 2 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
telencephalon development GO:0021537 186 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
cellular response to lipid GO:0071396 145 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
positive regulation of thymocyte migration GO:2000412 2 0.013
regulation of cytokine production GO:0001817 266 0.013
protein ubiquitination GO:0016567 171 0.013
response to extracellular stimulus GO:0009991 127 0.013
response to inorganic substance GO:0010035 96 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
male gamete generation GO:0048232 285 0.013
potassium ion transport GO:0006813 52 0.013
regulation of body fluid levels GO:0050878 162 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
regulation of heart contraction GO:0008016 77 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
homeostasis of number of cells GO:0048872 210 0.013
circulatory system process GO:0003013 197 0.012
negative regulation of interleukin 5 production GO:0032714 4 0.012
organic hydroxy compound transport GO:0015850 93 0.012
regulation of interleukin 10 secretion GO:2001179 4 0.012
negative regulation of multi organism process GO:0043901 68 0.012
mesodermal cell migration GO:0008078 4 0.012
dendrite development GO:0016358 115 0.012
oxidation reduction process GO:0055114 342 0.012
glycoprotein metabolic process GO:0009100 116 0.012
regulation of engulfment of apoptotic cell GO:1901074 2 0.012
positive regulation of epithelial cell migration GO:0010634 19 0.012
Mouse
negative regulation of transferase activity GO:0051348 85 0.012
anatomical structure homeostasis GO:0060249 145 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
negative regulation of action potential GO:0045759 1 0.012
regulation of inflammatory response GO:0050727 147 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
axon guidance GO:0007411 141 0.012
wound healing GO:0042060 157 0.012
acetylcholine transport GO:0015870 2 0.012
cell chemotaxis GO:0060326 81 0.012
positive regulation of b cell activation GO:0050871 49 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
regulation of neural precursor cell proliferation GO:2000177 70 0.012
Mouse
mitotic cell cycle GO:0000278 195 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
regulation of neuroblast proliferation GO:1902692 27 0.011
Mouse
myeloid leukocyte migration GO:0097529 57 0.011
rhythmic process GO:0048511 174 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
sensory perception of light stimulus GO:0050953 54 0.011
compound eye development GO:0048749 1 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
tissue homeostasis GO:0001894 115 0.011
cellular chemical homeostasis GO:0055082 215 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
regulation of homeostatic process GO:0032844 182 0.011
regulation of angiogenesis GO:0045765 81 0.011
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.011
stem cell differentiation GO:0048863 268 0.011
inner ear morphogenesis GO:0042472 101 0.011
angiogenesis GO:0001525 201 0.011
Mouse
leukocyte mediated immunity GO:0002443 174 0.011
prevention of polyspermy GO:0060468 4 0.011
cell type specific apoptotic process GO:0097285 268 0.011
heterocycle catabolic process GO:0046700 280 0.011
digestive system development GO:0055123 200 0.011
protein localization to nucleus GO:0034504 121 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
lymphocyte proliferation GO:0046651 164 0.011
cellular lipid metabolic process GO:0044255 323 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.011
neuron death GO:0070997 154 0.011
lung development GO:0030324 164 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
negative regulation of protein modification process GO:0031400 163 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
midgut development GO:0007494 4 0.011
regulation of actin nucleation GO:0051125 4 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
response to decreased oxygen levels GO:0036293 59 0.011
defense response to gram positive bacterium GO:0050830 50 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
negative regulation of organelle organization GO:0010639 90 0.011
positive regulation of transferase activity GO:0051347 167 0.010
thymocyte migration GO:0072679 2 0.010
positive regulation of cellular amine metabolic process GO:0033240 5 0.010
response to oxygen levels GO:0070482 62 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
ribose phosphate biosynthetic process GO:0046390 59 0.010
norepinephrine secretion GO:0048243 2 0.010
organic anion transport GO:0015711 137 0.010
positive regulation of eosinophil migration GO:2000418 2 0.010
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.010
cognition GO:0050890 149 0.010
nuclear transport GO:0051169 139 0.010
interleukin 10 secretion GO:0072608 4 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
viral gene expression GO:0019080 3 0.010
developmental maturation GO:0021700 193 0.010
peptidyl serine modification GO:0018209 83 0.010
acetate ester transport GO:1901374 2 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
amino acid transport GO:0006865 61 0.010
germ cell development GO:0007281 185 0.010
regulation of hydrolase activity GO:0051336 246 0.010
nucleoside catabolic process GO:0009164 206 0.010
positive regulation of cell adhesion GO:0045785 80 0.010
detection of stimulus GO:0051606 84 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
cartilage development GO:0051216 140 0.010
regulation of cell adhesion GO:0030155 154 0.010
regulation of eosinophil migration GO:2000416 2 0.010
positive regulation of interleukin 8 production GO:0032757 2 0.010
interleukin 6 production GO:0032635 58 0.010

Prl2a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.013
lipid metabolism disorder DOID:3146 0 0.013