Mus musculus

75 known processes

Klre1

killer cell lectin-like receptor family E member 1

(Aliases: NKG2I,Klre-1)

Klre1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.220
regulation of cytokine production GO:0001817 266 0.153
leukocyte mediated cytotoxicity GO:0001909 62 0.149
cytokine production GO:0001816 319 0.130
regulation of natural killer cell mediated immunity GO:0002715 19 0.119
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.114
lymphocyte mediated immunity GO:0002449 139 0.112
regulation of defense response GO:0031347 233 0.109
cellular response to lipopolysaccharide GO:0071222 77 0.105
Mouse
regulation of innate immune response GO:0045088 91 0.104
positive regulation of cytokine production GO:0001819 174 0.101
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.099
Mouse
response to molecule of bacterial origin GO:0002237 143 0.098
Mouse
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.090
cell killing GO:0001906 67 0.090
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.089
positive regulation of leukocyte mediated immunity GO:0002705 70 0.082
immune response regulating signaling pathway GO:0002764 125 0.081
response to lipopolysaccharide GO:0032496 128 0.079
Mouse
leukocyte mediated immunity GO:0002443 174 0.079
innate immune response GO:0045087 157 0.075
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.073
cation transport GO:0006812 399 0.073
cellular response to lipid GO:0071396 145 0.072
Mouse
positive regulation of defense response GO:0031349 124 0.071
adaptive immune response GO:0002250 155 0.070
positive regulation of innate immune response GO:0045089 80 0.066
reactive oxygen species metabolic process GO:0072593 84 0.063
natural killer cell mediated immunity GO:0002228 29 0.061
cellular response to molecule of bacterial origin GO:0071219 83 0.060
Mouse
immune effector process GO:0002252 321 0.059
detection of yeast GO:0001879 2 0.058
Mouse
cellular amino acid metabolic process GO:0006520 103 0.058
macromolecule catabolic process GO:0009057 281 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.055
cell adhesion GO:0007155 329 0.053
Mouse
regulation of protein localization GO:0032880 231 0.052
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.051
reactive oxygen species biosynthetic process GO:1903409 8 0.051
myeloid cell differentiation GO:0030099 233 0.051
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.050
nucleobase containing small molecule metabolic process GO:0055086 352 0.050
positive regulation of cell killing GO:0031343 33 0.049
mapk cascade GO:0000165 281 0.049
small gtpase mediated signal transduction GO:0007264 97 0.049
regulation of hormone levels GO:0010817 211 0.047
regulation of mapk cascade GO:0043408 248 0.047
regulation of secretion by cell GO:1903530 249 0.047
regulation of hydrolase activity GO:0051336 246 0.047
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.046
regulation of leukocyte mediated immunity GO:0002703 104 0.046
organic cyclic compound catabolic process GO:1901361 295 0.046
leukocyte activation involved in immune response GO:0002366 126 0.046
Mouse
regulation of establishment of protein localization GO:0070201 181 0.045
cytokine secretion GO:0050663 72 0.045
cellular amine metabolic process GO:0044106 44 0.044
response to molecule of fungal origin GO:0002238 4 0.043
Mouse
purine containing compound metabolic process GO:0072521 311 0.043
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.043
detection of fungus GO:0016046 2 0.043
Mouse
apoptotic signaling pathway GO:0097190 306 0.043
regulation of cytokine secretion GO:0050707 61 0.042
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.042
single organism cell adhesion GO:0098602 156 0.042
Mouse
cellular ketone metabolic process GO:0042180 84 0.042
cell type specific apoptotic process GO:0097285 268 0.041
nitrogen compound transport GO:0071705 271 0.041
positive regulation of protein transport GO:0051222 93 0.040
g protein coupled receptor signaling pathway GO:0007186 243 0.040
regulation of lymphocyte activation GO:0051249 240 0.040
leukocyte differentiation GO:0002521 342 0.039
positive regulation of immune effector process GO:0002699 107 0.039
natural killer cell mediated cytotoxicity GO:0042267 29 0.039
reactive nitrogen species metabolic process GO:2001057 0 0.039
ras protein signal transduction GO:0007265 77 0.038
negative regulation of immune system process GO:0002683 209 0.038
Rat
regulation of cell killing GO:0031341 40 0.037
defense response to other organism GO:0098542 197 0.037
Mouse
t cell activation GO:0042110 289 0.037
positive regulation of programmed cell death GO:0043068 218 0.036
cell activation involved in immune response GO:0002263 126 0.036
Mouse
positive regulation of cell death GO:0010942 224 0.036
cellular response to biotic stimulus GO:0071216 92 0.036
Mouse
cellular homeostasis GO:0019725 240 0.035
amine metabolic process GO:0009308 45 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.034
regulation of cellular catabolic process GO:0031329 242 0.033
cellular response to cytokine stimulus GO:0071345 189 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
heterocycle catabolic process GO:0046700 280 0.033
regulation of secretion GO:0051046 274 0.033
regulation of protein transport GO:0051223 163 0.032
angiogenesis GO:0001525 201 0.032
aromatic compound catabolic process GO:0019439 286 0.032
calcium ion homeostasis GO:0055074 127 0.031
membrane organization GO:0061024 245 0.031
Mouse
positive regulation of secretion GO:0051047 130 0.031
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.031
negative regulation of protein metabolic process GO:0051248 282 0.031
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
regulation of lymphocyte mediated immunity GO:0002706 84 0.030
negative regulation of growth GO:0045926 99 0.030
negative regulation of phosphate metabolic process GO:0045936 184 0.030
muscle tissue development GO:0060537 308 0.030
regulation of vesicle mediated transport GO:0060627 139 0.030
Mouse
regulation of cell migration GO:0030334 219 0.029
interferon gamma production GO:0032609 67 0.029
defense response to gram positive bacterium GO:0050830 50 0.029
Mouse
regulation of blood pressure GO:0008217 93 0.029
anion transport GO:0006820 177 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
immune response activating signal transduction GO:0002757 116 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.028
protein secretion GO:0009306 111 0.028
protein maturation GO:0051604 176 0.028
intracellular protein transport GO:0006886 204 0.028
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.027
inflammatory response GO:0006954 244 0.027
positive regulation of apoptotic process GO:0043065 217 0.027
divalent inorganic cation transport GO:0072511 178 0.027
cation homeostasis GO:0055080 212 0.026
rho protein signal transduction GO:0007266 32 0.026
dna metabolic process GO:0006259 303 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
regulation of interferon gamma production GO:0032649 57 0.026
regulation of intracellular transport GO:0032386 159 0.026
interspecies interaction between organisms GO:0044419 83 0.026
cell recognition GO:0008037 83 0.026
Mouse
detection of other organism GO:0098543 8 0.025
Mouse
cellular chemical homeostasis GO:0055082 215 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
regulation of cellular amine metabolic process GO:0033238 20 0.024
nucleoside catabolic process GO:0009164 206 0.024
divalent inorganic cation homeostasis GO:0072507 138 0.024
regulation of transferase activity GO:0051338 263 0.024
regulation of protein kinase activity GO:0045859 232 0.024
antigen processing and presentation GO:0019882 47 0.024
activation of innate immune response GO:0002218 56 0.024
multicellular organismal homeostasis GO:0048871 164 0.024
negative regulation of multi organism process GO:0043901 68 0.024
positive regulation of secretion by cell GO:1903532 114 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
striated muscle tissue development GO:0014706 293 0.023
response to acid chemical GO:0001101 111 0.023
positive regulation of protein secretion GO:0050714 52 0.023
positive regulation of protein modification process GO:0031401 299 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
anatomical structure homeostasis GO:0060249 145 0.023
single organismal cell cell adhesion GO:0016337 131 0.023
Mouse
regulation of ion transport GO:0043269 215 0.023
endocytosis GO:0006897 168 0.023
Mouse
regulation of proteolysis GO:0030162 164 0.023
protein processing GO:0016485 163 0.023
positive regulation of kinase activity GO:0033674 155 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
regulation of cell motility GO:2000145 236 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.023
organophosphate catabolic process GO:0046434 232 0.023
nucleoside metabolic process GO:0009116 246 0.023
positive regulation of hydrolase activity GO:0051345 148 0.022
regulation of protein secretion GO:0050708 82 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
blood vessel morphogenesis GO:0048514 285 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
activation of immune response GO:0002253 138 0.022
regulation of adaptive immune response GO:0002819 90 0.022
cellular lipid metabolic process GO:0044255 323 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
t cell mediated immunity GO:0002456 50 0.022
regulation of kinase activity GO:0043549 249 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
positive regulation of endocytosis GO:0045807 42 0.022
Mouse
leukocyte migration GO:0050900 124 0.021
action potential GO:0001508 78 0.021
muscle fiber development GO:0048747 76 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
response to organonitrogen compound GO:0010243 246 0.021
nucleotide metabolic process GO:0009117 332 0.021
regulation of systemic arterial blood pressure GO:0003073 61 0.021
regulation of cell activation GO:0050865 289 0.021
detection of stimulus GO:0051606 84 0.021
Mouse
cellular ion homeostasis GO:0006873 165 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
protein catabolic process GO:0030163 221 0.021
regulation of angiotensin metabolic process GO:0060177 4 0.021
leukocyte proliferation GO:0070661 172 0.021
regulation of inflammatory response GO:0050727 147 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
regulation of ion homeostasis GO:2000021 64 0.020
innate immune response activating signal transduction GO:0002758 50 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
regulation of membrane potential GO:0042391 192 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
regulation of ras protein signal transduction GO:0046578 114 0.020
ossification GO:0001503 216 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
metal ion homeostasis GO:0055065 189 0.020
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.020
Mouse
positive regulation of cell motility GO:2000147 116 0.020
protein localization to organelle GO:0033365 185 0.020
hormone secretion GO:0046879 128 0.019
carbohydrate metabolic process GO:0005975 230 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
homeostasis of number of cells GO:0048872 210 0.019
synaptic transmission GO:0007268 329 0.019
circulatory system process GO:0003013 197 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
blood circulation GO:0008015 195 0.019
response to growth factor GO:0070848 198 0.019
multicellular organismal signaling GO:0035637 91 0.019
regulation of response to wounding GO:1903034 189 0.019
transmembrane transport GO:0055085 412 0.019
lymphocyte activation involved in immune response GO:0002285 93 0.019
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.019
meiotic cell cycle GO:0051321 122 0.019
organic acid transport GO:0015849 101 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.019
muscle cell differentiation GO:0042692 261 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
cellular response to acid chemical GO:0071229 68 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.019
organic anion transport GO:0015711 137 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
purine containing compound catabolic process GO:0072523 213 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
regulation of cell adhesion GO:0030155 154 0.019
negative regulation of molecular function GO:0044092 258 0.019
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.018
positive regulation of transferase activity GO:0051347 167 0.018
defense response to bacterium GO:0042742 119 0.018
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
male gamete generation GO:0048232 285 0.018
positive regulation of proteolysis GO:0045862 85 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
peptidyl amino acid modification GO:0018193 336 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
positive regulation of t cell activation GO:0050870 101 0.018
maintenance of location GO:0051235 89 0.018
regulation of multi organism process GO:0043900 111 0.018
divalent metal ion transport GO:0070838 172 0.018
mature dendritic cell differentiation GO:0097029 3 0.018
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
spermatogenesis GO:0007283 284 0.018
telencephalon development GO:0021537 186 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
cytokine mediated signaling pathway GO:0019221 115 0.018
regulation of angiotensin levels in blood GO:0002002 4 0.018
positive regulation of lymphocyte activation GO:0051251 140 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
tissue remodeling GO:0048771 102 0.018
oxidation reduction process GO:0055114 342 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
regulation of organelle organization GO:0033043 289 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
tissue homeostasis GO:0001894 115 0.017
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.017
nucleotide catabolic process GO:0009166 217 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
fertilization GO:0009566 127 0.017
sequestering of calcium ion GO:0051208 18 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
positive regulation of cell migration GO:0030335 109 0.017
regulation of peptidase activity GO:0052547 96 0.017
sequestering of metal ion GO:0051238 19 0.017
glycoprotein metabolic process GO:0009100 116 0.017
cytoplasmic transport GO:0016482 234 0.016
production of molecular mediator of immune response GO:0002440 103 0.016
regulation of homeostatic process GO:0032844 182 0.016
pattern recognition receptor signaling pathway GO:0002221 47 0.016
Mouse
i kappab kinase nf kappab signaling GO:0007249 85 0.016
regulation of endocytosis GO:0030100 69 0.016
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.016
positive regulation of cell activation GO:0050867 158 0.016
nuclear transport GO:0051169 139 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
response to organic cyclic compound GO:0014070 198 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
b cell activation GO:0042113 161 0.016
protein ubiquitination GO:0016567 171 0.016
t cell mediated cytotoxicity GO:0001913 26 0.016
carboxylic acid transport GO:0046942 100 0.016
gtp metabolic process GO:0046039 144 0.016
sensory perception GO:0007600 245 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
calcium ion transport GO:0006816 159 0.016
regulation of anatomical structure size GO:0090066 178 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
regulation of tumor necrosis factor production GO:0032680 49 0.016
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.016
regulation of cellular response to stress GO:0080135 159 0.016
germ cell development GO:0007281 185 0.016
protein localization to nucleus GO:0034504 121 0.016
regulation of map kinase activity GO:0043405 120 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
interleukin 1 production GO:0032612 31 0.015
regulation of cysteine type endopeptidase activity GO:2000116 65 0.015
alpha beta t cell activation GO:0046631 91 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
organelle fission GO:0048285 170 0.015
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.015
transmission of nerve impulse GO:0019226 76 0.015
lipid localization GO:0010876 126 0.015
gland development GO:0048732 330 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
response to drug GO:0042493 75 0.015
Mouse
glycoprotein biosynthetic process GO:0009101 89 0.014
gtp catabolic process GO:0006184 143 0.014
muscle cell development GO:0055001 133 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
multi multicellular organism process GO:0044706 109 0.014
activation of mapk activity GO:0000187 59 0.014
regulation of angiogenesis GO:0045765 81 0.014
cognition GO:0050890 149 0.014
regulation of natural killer cell activation GO:0032814 22 0.014
skeletal muscle organ development GO:0060538 163 0.014
response to peptide GO:1901652 136 0.014
transepithelial chloride transport GO:0030321 4 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
positive regulation of phagocytosis GO:0050766 26 0.014
Mouse
endomembrane system organization GO:0010256 147 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
positive regulation of adaptive immune response GO:0002821 61 0.014
amide transport GO:0042886 138 0.014
organic hydroxy compound transport GO:0015850 93 0.014
regulation of striated muscle cell differentiation GO:0051153 81 0.014
peptide transport GO:0015833 133 0.014
positive regulation of tumor necrosis factor production GO:0032760 30 0.014
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
positive regulation of map kinase activity GO:0043406 84 0.014
spermatid development GO:0007286 108 0.014
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
peptide hormone secretion GO:0030072 109 0.014
negative regulation of defense response GO:0031348 77 0.014
Rat
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
chemotaxis GO:0006935 247 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
guanosine containing compound metabolic process GO:1901068 144 0.014
establishment of protein localization to organelle GO:0072594 118 0.013
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
forebrain development GO:0030900 302 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
regulation of cell projection organization GO:0031344 206 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
carbohydrate homeostasis GO:0033500 128 0.013
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
exocytosis GO:0006887 121 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
meiotic nuclear division GO:0007126 115 0.013
phagocytosis GO:0006909 66 0.013
Mouse
nuclear division GO:0000280 158 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
cellular response to molecule of fungal origin GO:0071226 2 0.013
Mouse
lymphocyte differentiation GO:0030098 242 0.013
positive regulation of lymphocyte proliferation GO:0050671 70 0.013
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.013
Mouse
myeloid leukocyte activation GO:0002274 83 0.013
protein targeting GO:0006605 143 0.013
regulation of muscle tissue development GO:1901861 97 0.013
positive regulation of gtpase activity GO:0043547 85 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.013
cellular protein catabolic process GO:0044257 155 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
renal system development GO:0072001 225 0.012
lymphocyte homeostasis GO:0002260 64 0.012
monosaccharide transport GO:0015749 58 0.012
positive regulation of intracellular transport GO:0032388 70 0.012
regulation of rho protein signal transduction GO:0035023 71 0.012
response to transforming growth factor beta GO:0071559 88 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
amino acid transport GO:0006865 61 0.012
erk1 and erk2 cascade GO:0070371 77 0.012
detection of external biotic stimulus GO:0098581 9 0.012
Mouse
organophosphate biosynthetic process GO:0090407 122 0.012
sulfur compound metabolic process GO:0006790 100 0.012
neuronal action potential GO:0019228 54 0.012
regulation of production of molecular mediator of immune response GO:0002700 65 0.012
nitric oxide biosynthetic process GO:0006809 25 0.012
Mouse
nitric oxide metabolic process GO:0046209 25 0.012
Mouse
regulation of b cell activation GO:0050864 81 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
regulation of ossification GO:0030278 112 0.012
glucose homeostasis GO:0042593 128 0.012
peptide secretion GO:0002790 114 0.012
leukocyte homeostasis GO:0001776 79 0.012
negative regulation of nik nf kappab signaling GO:1901223 2 0.012
ion transmembrane transport GO:0034220 361 0.012
negative regulation of macrophage apoptotic process GO:2000110 3 0.012
striated muscle cell development GO:0055002 125 0.012
glucose transport GO:0015758 56 0.012
positive regulation of interferon gamma production GO:0032729 39 0.012
regulation of peptide transport GO:0090087 91 0.012
negative regulation of hydrolase activity GO:0051346 71 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
positive regulation of cytokine secretion GO:0050715 41 0.011
epithelial cell proliferation GO:0050673 174 0.011
t cell activation involved in immune response GO:0002286 43 0.011
cellular protein complex assembly GO:0043623 116 0.011
cation transmembrane transport GO:0098655 266 0.011
positive regulation of phospholipase activity GO:0010518 3 0.011
carbohydrate transport GO:0008643 62 0.011
interleukin 8 secretion GO:0072606 3 0.011
response to light stimulus GO:0009416 135 0.011
regulation of cell cycle GO:0051726 281 0.011
myotube differentiation GO:0014902 105 0.011
respiratory tube development GO:0030323 167 0.011
positive regulation of ras gtpase activity GO:0032320 65 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
positive regulation of nervous system development GO:0051962 221 0.011
regulation of phagocytosis GO:0050764 33 0.011
Mouse
single organism nuclear import GO:1902593 95 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
regulation of translation GO:0006417 71 0.011
neuron apoptotic process GO:0051402 142 0.011
lipid transport GO:0006869 98 0.011
negative regulation of protein modification process GO:0031400 163 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
lipid biosynthetic process GO:0008610 179 0.011
t cell differentiation GO:0030217 174 0.011
organelle assembly GO:0070925 177 0.011
hexose transport GO:0008645 56 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
stem cell differentiation GO:0048863 268 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.011
immunoglobulin production GO:0002377 73 0.011
regulation of nitric oxide biosynthetic process GO:0045428 18 0.011
Mouse
negative regulation of cell cycle GO:0045786 123 0.011
single fertilization GO:0007338 82 0.011
urogenital system development GO:0001655 261 0.011
regulation of myotube differentiation GO:0010830 62 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
growth of symbiont involved in interaction with host GO:0044116 23 0.011
regulation of protein catabolic process GO:0042176 108 0.011
lymphocyte proliferation GO:0046651 164 0.011
positive regulation of ion transport GO:0043270 65 0.011
cell chemotaxis GO:0060326 81 0.011
stress activated mapk cascade GO:0051403 80 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
organelle localization GO:0051640 179 0.011
positive regulation of cell adhesion GO:0045785 80 0.010
mitochondrion organization GO:0007005 134 0.010
leukocyte apoptotic process GO:0071887 71 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
regulation of system process GO:0044057 200 0.010
natural killer cell activation GO:0030101 44 0.010
negative regulation of nervous system development GO:0051961 156 0.010
regulation of t cell proliferation GO:0042129 92 0.010
cell substrate adhesion GO:0031589 130 0.010
mrna metabolic process GO:0016071 84 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
mitotic cell cycle GO:0000278 195 0.010
cellular response to drug GO:0035690 15 0.010
Mouse
regulation of growth of symbiont in host GO:0044126 19 0.010
response to radiation GO:0009314 165 0.010
growth of symbiont in host GO:0044117 23 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
positive regulation of inflammatory response GO:0050729 47 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
response to nutrient levels GO:0031667 109 0.010
receptor mediated endocytosis GO:0006898 51 0.010
Mouse
nuclear import GO:0051170 95 0.010
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.010
jnk cascade GO:0007254 72 0.010

Klre1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
immune system disease DOID:2914 0 0.012
disease of metabolism DOID:0014667 0 0.012