Mus musculus

0 known processes

Sh3kbp1

SH3-domain kinase binding protein 1

(Aliases: Ruk,1200007H22Rik,IN85,Seta,1700125L08Rik,5830464D22Rik,AI447724)

Sh3kbp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.837
synaptic transmission GO:0007268 329 0.741
memory GO:0007613 58 0.678
regulation of cellular amine metabolic process GO:0033238 20 0.606
cellular amine metabolic process GO:0044106 44 0.589
negative regulation of phosphorylation GO:0042326 166 0.577
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.548
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.529
organophosphate catabolic process GO:0046434 232 0.493
small gtpase mediated signal transduction GO:0007264 97 0.492
regulation of cytoskeleton organization GO:0051493 122 0.487
Mouse
regulation of actin filament length GO:0030832 45 0.468
establishment of organelle localization GO:0051656 122 0.460
regulation of kinase activity GO:0043549 249 0.459
olfactory learning GO:0008355 2 0.451
regulation of protein kinase activity GO:0045859 232 0.414
gtp metabolic process GO:0046039 144 0.398
purine nucleotide metabolic process GO:0006163 302 0.396
regulation of mapk cascade GO:0043408 248 0.391
negative regulation of phosphorus metabolic process GO:0010563 184 0.380
ion transmembrane transport GO:0034220 361 0.369
glycosyl compound catabolic process GO:1901658 206 0.362
locomotory behavior GO:0007626 195 0.354
purine containing compound metabolic process GO:0072521 311 0.342
guanosine containing compound catabolic process GO:1901069 144 0.337
cellular nitrogen compound catabolic process GO:0044270 280 0.315
negative regulation of protein phosphorylation GO:0001933 126 0.313
negative regulation of phosphate metabolic process GO:0045936 184 0.312
regulation of b cell differentiation GO:0045577 23 0.312
mapk cascade GO:0000165 281 0.312
positive regulation of mapk cascade GO:0043410 170 0.304
guanosine containing compound metabolic process GO:1901068 144 0.304
ribonucleotide catabolic process GO:0009261 208 0.300
cellular response to growth factor stimulus GO:0071363 197 0.288
glycosyl compound metabolic process GO:1901657 246 0.282
nucleotide catabolic process GO:0009166 217 0.282
amine metabolic process GO:0009308 45 0.277
regulation of actin polymerization or depolymerization GO:0008064 45 0.277
regulation of gtp catabolic process GO:0033124 113 0.277
leukocyte differentiation GO:0002521 342 0.275
negative regulation of cellular amine metabolic process GO:0033239 1 0.272
purine nucleoside triphosphate catabolic process GO:0009146 203 0.267
positive regulation of ras gtpase activity GO:0032320 65 0.265
purine nucleoside catabolic process GO:0006152 205 0.261
organic cyclic compound catabolic process GO:1901361 295 0.261
negative regulation of cellular protein metabolic process GO:0032269 247 0.253
gtp catabolic process GO:0006184 143 0.252
actin cytoskeleton organization GO:0030036 220 0.251
Mouse Fly
actin filament polymerization GO:0030041 44 0.248
positive regulation of cellular catabolic process GO:0031331 148 0.247
mitotic cell cycle GO:0000278 195 0.246
purine ribonucleoside metabolic process GO:0046128 241 0.245
purine nucleotide catabolic process GO:0006195 211 0.243
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.243
phospholipid metabolic process GO:0006644 87 0.241
organonitrogen compound catabolic process GO:1901565 264 0.240
cation transport GO:0006812 399 0.234
synaptic transmission gabaergic GO:0051932 19 0.228
cellular ketone metabolic process GO:0042180 84 0.226
negative regulation of protein metabolic process GO:0051248 282 0.225
membrane organization GO:0061024 245 0.225
positive regulation of leukocyte differentiation GO:1902107 86 0.223
neuron neuron synaptic transmission GO:0007270 69 0.221
transmembrane transport GO:0055085 412 0.220
regulation of transferase activity GO:0051338 263 0.220
ribonucleoside metabolic process GO:0009119 245 0.219
ribonucleoside catabolic process GO:0042454 206 0.216
activation of immune response GO:0002253 138 0.215
purine ribonucleotide metabolic process GO:0009150 290 0.215
regulation of cell projection organization GO:0031344 206 0.214
regulation of cellular catabolic process GO:0031329 242 0.208
positive regulation of gtp catabolic process GO:0033126 85 0.208
regulation of cell activation GO:0050865 289 0.205
cell junction maintenance GO:0034331 4 0.203
learning or memory GO:0007611 148 0.202
sequestering of metal ion GO:0051238 19 0.202
circulatory system process GO:0003013 197 0.202
sensory perception GO:0007600 245 0.200
purine nucleoside triphosphate metabolic process GO:0009144 226 0.199
mitotic cell cycle process GO:1903047 159 0.199
ribonucleotide metabolic process GO:0009259 291 0.194
negative regulation of protein tyrosine kinase activity GO:0061099 3 0.190
nucleoside triphosphate metabolic process GO:0009141 230 0.190
response to organonitrogen compound GO:0010243 246 0.189
regulation of ion transport GO:0043269 215 0.188
adult behavior GO:0030534 135 0.187
regulation of secretion by cell GO:1903530 249 0.186
synaptic vesicle recycling GO:0036465 19 0.186
regulation of organelle organization GO:0033043 289 0.185
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.185
glutamate receptor signaling pathway GO:0007215 35 0.182
cation transmembrane transport GO:0098655 266 0.180
regulation of anatomical structure size GO:0090066 178 0.179
positive regulation of cellular amine metabolic process GO:0033240 5 0.179
nucleoside phosphate catabolic process GO:1901292 222 0.179
divalent metal ion transport GO:0070838 172 0.178
regulation of intracellular transport GO:0032386 159 0.176
regulation of hydrolase activity GO:0051336 246 0.176
regulation of actin filament based process GO:0032970 99 0.176
Mouse
regulation of rho gtpase activity GO:0032319 58 0.175
regulation of system process GO:0044057 200 0.174
nucleotide metabolic process GO:0009117 332 0.172
positive regulation of rho gtpase activity GO:0032321 41 0.166
regulation of actin filament polymerization GO:0030833 38 0.164
cytokinesis GO:0000910 17 0.163
Fly
behavioral response to nutrient GO:0051780 1 0.163
nucleoside phosphate metabolic process GO:0006753 338 0.161
immune response activating signal transduction GO:0002757 116 0.160
regulation of purine nucleotide metabolic process GO:1900542 169 0.159
inorganic ion transmembrane transport GO:0098660 234 0.159
regulation of vesicle mediated transport GO:0060627 139 0.157
Fly
positive regulation of cell death GO:0010942 224 0.156
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.153
regulation of secretion GO:0051046 274 0.152
positive regulation of gtpase activity GO:0043547 85 0.149
heterocycle catabolic process GO:0046700 280 0.149
regulation of synaptic plasticity GO:0048167 87 0.149
purine nucleoside metabolic process GO:0042278 241 0.149
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.148
synaptic vesicle transport GO:0048489 57 0.147
axonogenesis GO:0007409 274 0.145
positive regulation of nervous system development GO:0051962 221 0.145
regulation of cellular component size GO:0032535 121 0.144
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.144
establishment of vesicle localization GO:0051650 81 0.143
ribose phosphate metabolic process GO:0019693 291 0.141
adult locomotory behavior GO:0008344 91 0.140
organelle localization GO:0051640 179 0.137
ribonucleoside triphosphate metabolic process GO:0009199 220 0.136
negative regulation of mapk cascade GO:0043409 65 0.136
regulation of cellular ketone metabolic process GO:0010565 66 0.135
aromatic compound catabolic process GO:0019439 286 0.134
positive regulation of lymphocyte differentiation GO:0045621 61 0.133
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.129
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.128
regulation of ras protein signal transduction GO:0046578 114 0.127
ribonucleoside triphosphate catabolic process GO:0009203 199 0.127
axon guidance GO:0007411 141 0.125
b cell receptor signaling pathway GO:0050853 20 0.122
trivalent inorganic cation transport GO:0072512 5 0.121
cellular amino acid metabolic process GO:0006520 103 0.119
muscle cell differentiation GO:0042692 261 0.117
regulation of erbb signaling pathway GO:1901184 16 0.116
cation homeostasis GO:0055080 212 0.116
positive regulation of transferase activity GO:0051347 167 0.116
cognition GO:0050890 149 0.115
inorganic cation transmembrane transport GO:0098662 207 0.115
negative regulation of kinase activity GO:0033673 81 0.114
regulation of neuron differentiation GO:0045664 281 0.112
cytoplasmic transport GO:0016482 234 0.111
establishment of synaptic vesicle localization GO:0097480 57 0.111
rho protein signal transduction GO:0007266 32 0.111
short term memory GO:0007614 5 0.111
regulation of t cell activation GO:0050863 170 0.111
g protein coupled receptor signaling pathway GO:0007186 243 0.111
negative regulation of epidermal growth factor activated receptor activity GO:0007175 3 0.110
regulation of nucleotide catabolic process GO:0030811 122 0.110
positive regulation of kinase activity GO:0033674 155 0.108
engulfment of apoptotic cell GO:0043652 3 0.107
blood vessel morphogenesis GO:0048514 285 0.106
negative regulation of protein modification process GO:0031400 163 0.105
regulation of lymphocyte differentiation GO:0045619 107 0.104
synaptic vesicle localization GO:0097479 59 0.104
negative regulation of cell proliferation GO:0008285 296 0.103
positive regulation of necrotic cell death GO:0010940 1 0.102
nucleobase containing small molecule metabolic process GO:0055086 352 0.101
peptidyl serine modification GO:0018209 83 0.101
negative regulation of cellular component organization GO:0051129 194 0.101
regulation of neuron projection development GO:0010975 169 0.101
negative regulation of transferase activity GO:0051348 85 0.097
nucleoside triphosphate catabolic process GO:0009143 205 0.097
regulation of protein localization GO:0032880 231 0.097
Mouse
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.096
sensory organ morphogenesis GO:0090596 242 0.096
Fly
organic hydroxy compound metabolic process GO:1901615 203 0.096
regulation of ion transmembrane transporter activity GO:0032412 54 0.096
positive regulation of rac gtpase activity GO:0032855 14 0.096
regulation of protein complex assembly GO:0043254 83 0.095
release of sequestered calcium ion into cytosol GO:0051209 42 0.093
regulation of leukocyte differentiation GO:1902105 159 0.092
b 1 b cell differentiation GO:0001923 3 0.092
protein kinase b signaling GO:0043491 74 0.091
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.091
purine ribonucleoside catabolic process GO:0046130 205 0.090
response to growth factor GO:0070848 198 0.090
response to peptide hormone GO:0043434 127 0.090
receptor internalization GO:0031623 16 0.090
regulation of membrane potential GO:0042391 192 0.089
b cell differentiation GO:0030183 78 0.089
cytokine production GO:0001816 319 0.089
Mouse
learning GO:0007612 98 0.088
nucleoside metabolic process GO:0009116 246 0.088
cell junction organization GO:0034330 77 0.087
embryonic placenta development GO:0001892 98 0.086
membrane tubulation GO:0097320 4 0.085
synapse organization GO:0050808 125 0.085
cellular ion homeostasis GO:0006873 165 0.085
endomembrane system organization GO:0010256 147 0.084
cell division GO:0051301 120 0.083
Fly
sensory perception of mechanical stimulus GO:0050954 107 0.083
regulation of cell migration GO:0030334 219 0.082
macromolecule catabolic process GO:0009057 281 0.082
spermatogenesis GO:0007283 284 0.082
negative regulation of molecular function GO:0044092 258 0.082
developmental maturation GO:0021700 193 0.081
regulation of ras gtpase activity GO:0032318 88 0.081
carbohydrate derivative catabolic process GO:1901136 231 0.080
regulation of epidermal growth factor activated receptor activity GO:0007176 7 0.080
regulation of exocytosis GO:0017157 61 0.079
positive regulation of cell development GO:0010720 237 0.079
purine ribonucleotide catabolic process GO:0009154 208 0.079
synaptic vesicle endocytosis GO:0048488 19 0.078
regionalization GO:0003002 337 0.078
cellular homeostasis GO:0019725 240 0.078
nucleoside catabolic process GO:0009164 206 0.077
peptidyl tyrosine modification GO:0018212 145 0.077
regulation of t cell proliferation GO:0042129 92 0.074
peptidyl amino acid modification GO:0018193 336 0.074
peptidyl serine phosphorylation GO:0018105 74 0.074
heart process GO:0003015 94 0.074
regulation of cell cycle GO:0051726 281 0.074
negative regulation of homeostatic process GO:0032845 71 0.073
leukocyte migration GO:0050900 124 0.073
positive regulation of protein phosphorylation GO:0001934 242 0.073
cellular protein complex assembly GO:0043623 116 0.073
blood circulation GO:0008015 195 0.073
placenta development GO:0001890 140 0.073
mitotic cytokinesis GO:0000281 4 0.072
regulation of cd24 biosynthetic process GO:2000559 1 0.072
notch signaling pathway GO:0007219 71 0.071
regulation of lymphocyte proliferation GO:0050670 117 0.071
spermatid differentiation GO:0048515 115 0.070
protein catabolic process GO:0030163 221 0.070
regulation of body fluid levels GO:0050878 162 0.069
labyrinthine layer development GO:0060711 49 0.069
cell adhesion GO:0007155 329 0.068
regulation of mast cell activation GO:0033003 21 0.068
activation of meiosis GO:0090427 4 0.068
regulation of glutamate receptor signaling pathway GO:1900449 16 0.067
negative regulation of intracellular signal transduction GO:1902532 167 0.067
renal system development GO:0072001 225 0.067
small molecule biosynthetic process GO:0044283 132 0.067
embryonic organ morphogenesis GO:0048562 276 0.067
alcohol metabolic process GO:0006066 116 0.066
regulation of erk1 and erk2 cascade GO:0070372 71 0.066
b 1a b cell differentiation GO:0002337 2 0.066
cellularization GO:0007349 1 0.065
regulation of transporter activity GO:0032409 57 0.064
adherens junction maintenance GO:0034334 1 0.064
regulation of neuronal synaptic plasticity GO:0048168 30 0.064
regulation of nucleoside metabolic process GO:0009118 130 0.064
urogenital system development GO:0001655 261 0.064
response to extracellular stimulus GO:0009991 127 0.064
lymphocyte proliferation GO:0046651 164 0.063
negative regulation of receptor activity GO:2000272 5 0.062
epithelial tube morphogenesis GO:0060562 303 0.062
regulation of postsynaptic membrane potential GO:0060078 48 0.062
germ cell development GO:0007281 185 0.062
Fly
lipid transport GO:0006869 98 0.062
camera type eye development GO:0043010 266 0.062
heart contraction GO:0060047 93 0.062
single organism cell adhesion GO:0098602 156 0.061
glycerolipid metabolic process GO:0046486 122 0.061
associative learning GO:0008306 61 0.060
actin polymerization or depolymerization GO:0008154 54 0.060
lipid localization GO:0010876 126 0.060
positive regulation of protein kinase activity GO:0045860 144 0.060
monocyte extravasation GO:0035696 2 0.060
regulation of actin cytoskeleton organization GO:0032956 84 0.060
Mouse
action potential GO:0001508 78 0.059
spermatid development GO:0007286 108 0.059
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.059
t cell differentiation in thymus GO:0033077 77 0.059
lateral inhibition GO:0046331 1 0.058
Fly
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.058
negative regulation of ras protein signal transduction GO:0046580 18 0.058
regulation of muscle system process GO:0090257 80 0.058
positive regulation of apoptotic process GO:0043065 217 0.057
regulation of heart contraction GO:0008016 77 0.057
divalent inorganic cation transport GO:0072511 178 0.057
regulation of synaptic transmission gabaergic GO:0032228 17 0.057
morphogenesis of a polarized epithelium GO:0001738 37 0.055
positive regulation of protein modification process GO:0031401 299 0.055
organophosphate biosynthetic process GO:0090407 122 0.055
regulation of ion transmembrane transport GO:0034765 119 0.055
developmental growth involved in morphogenesis GO:0060560 138 0.055
erk1 and erk2 cascade GO:0070371 77 0.055
multicellular organismal homeostasis GO:0048871 164 0.055
regulation of cellular component biogenesis GO:0044087 181 0.054
antigen receptor mediated signaling pathway GO:0050851 64 0.054
establishment or maintenance of cell polarity GO:0007163 86 0.054
angiogenesis GO:0001525 201 0.054
morphogenesis of a branching structure GO:0001763 203 0.053
carbohydrate derivative biosynthetic process GO:1901137 183 0.053
glial cell differentiation GO:0010001 131 0.053
regulation of cell cycle process GO:0010564 160 0.053
response to nutrient levels GO:0031667 109 0.053
positive regulation of secretion by cell GO:1903532 114 0.052
cell activation involved in immune response GO:0002263 126 0.052
negative regulation of cell migration GO:0030336 59 0.052
phospholipid transport GO:0015914 21 0.052
gastrulation GO:0007369 116 0.052
regulation of neurotransmitter levels GO:0001505 87 0.052
cellular chemical homeostasis GO:0055082 215 0.052
regulation of rho protein signal transduction GO:0035023 71 0.051
positive regulation of neuron projection development GO:0010976 79 0.051
positive regulation of organelle organization GO:0010638 128 0.051
regulation of proteolysis GO:0030162 164 0.050
chemotaxis GO:0006935 247 0.050
regulation of receptor activity GO:0010469 41 0.050
neuron projection guidance GO:0097485 141 0.050
regulation of cytokine production GO:0001817 266 0.050
Mouse
t cell anergy GO:0002870 4 0.049
b cell activation GO:0042113 161 0.049
regulation of protein catabolic process GO:0042176 108 0.049
vesicle organization GO:0016050 60 0.049
calcium ion homeostasis GO:0055074 127 0.049
calcium ion transmembrane transport GO:0070588 85 0.049
protein secretion GO:0009306 111 0.049
protein localization to membrane GO:0072657 108 0.048
sequestering of calcium ion GO:0051208 18 0.048
directional locomotion GO:0033058 3 0.048
fat cell differentiation GO:0045444 160 0.048
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.048
response to radiation GO:0009314 165 0.048
plasma membrane organization GO:0007009 90 0.047
insulin receptor signaling pathway GO:0008286 49 0.047
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.047
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.047
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.046
purine containing compound catabolic process GO:0072523 213 0.046
positive regulation of cell activation GO:0050867 158 0.046
digestive system development GO:0055123 200 0.046
regulation of circadian sleep wake cycle GO:0042749 3 0.046
homeostasis of number of cells GO:0048872 210 0.046
activation of meiosis involved in egg activation GO:0060466 2 0.045
regulation of transmembrane transport GO:0034762 128 0.045
negative regulation of t cell proliferation GO:0042130 38 0.045
positive regulation of protein catabolic process GO:0045732 60 0.045
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.045
regulation of apoptotic signaling pathway GO:2001233 197 0.045
positive regulation of nucleotide metabolic process GO:0045981 114 0.045
activation of mapk activity GO:0000187 59 0.045
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.044
leukocyte mediated immunity GO:0002443 174 0.044
negative regulation of cell development GO:0010721 169 0.044
regulation of monocyte extravasation GO:2000437 2 0.044
muscle system process GO:0003012 141 0.044
lipid biosynthetic process GO:0008610 179 0.044
forebrain development GO:0030900 302 0.044
branching morphogenesis of an epithelial tube GO:0048754 159 0.043
cellular protein catabolic process GO:0044257 155 0.043
canonical wnt signaling pathway GO:0060070 130 0.043
positive regulation of neuron differentiation GO:0045666 141 0.043
regulation of lymphocyte activation GO:0051249 240 0.042
wnt signaling pathway GO:0016055 188 0.042
anion transport GO:0006820 177 0.042
phagosome maturation GO:0090382 4 0.042
sensory perception of chemical stimulus GO:0007606 51 0.041
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.041
positive regulation of nucleoside metabolic process GO:0045979 91 0.041
cellular response to hormone stimulus GO:0032870 150 0.040
negative regulation of map kinase activity GO:0043407 34 0.040
embryonic epithelial tube formation GO:0001838 130 0.040
male gamete generation GO:0048232 285 0.040
cell growth GO:0016049 130 0.040
myeloid cell differentiation GO:0030099 233 0.040
dendrite development GO:0016358 115 0.040
regulation of nucleotide metabolic process GO:0006140 169 0.040
hemostasis GO:0007599 78 0.039
phospholipid biosynthetic process GO:0008654 36 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.039
multicellular organism growth GO:0035264 161 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.039
organic hydroxy compound transport GO:0015850 93 0.039
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 6 0.039
single organismal cell cell adhesion GO:0016337 131 0.039
synaptic vesicle membrane organization GO:0048499 1 0.039
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.039
regulation of blood circulation GO:1903522 93 0.039
metal ion homeostasis GO:0055065 189 0.038
peptidyl tyrosine phosphorylation GO:0018108 143 0.038
protein maturation GO:0051604 176 0.038
regulation of cellular protein catabolic process GO:1903362 61 0.038
cellular calcium ion homeostasis GO:0006874 119 0.038
neuromuscular process GO:0050905 99 0.038
cellular metal ion homeostasis GO:0006875 151 0.038
meiotic cell cycle GO:0051321 122 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
t cell proliferation GO:0042098 120 0.037
homotypic cell cell adhesion GO:0034109 28 0.037
regulation of cation channel activity GO:2001257 22 0.037
muscle contraction GO:0006936 101 0.037
regulation of protein serine threonine kinase activity GO:0071900 157 0.036
response to lipopolysaccharide GO:0032496 128 0.036
inflammatory response GO:0006954 244 0.035
negative regulation of erbb signaling pathway GO:1901185 7 0.035
regulation of cell division GO:0051302 76 0.035
olfactory bulb axon guidance GO:0071678 1 0.035
cellular divalent inorganic cation homeostasis GO:0072503 127 0.035
regulation of purine nucleotide catabolic process GO:0033121 122 0.035
microtubule cytoskeleton organization GO:0000226 157 0.035
cell cell junction organization GO:0045216 72 0.035
regulation of cell growth GO:0001558 91 0.035
divalent inorganic cation homeostasis GO:0072507 138 0.035
regulation of cell motility GO:2000145 236 0.035
organonitrogen compound biosynthetic process GO:1901566 192 0.035
lymphocyte differentiation GO:0030098 242 0.035
negative regulation of immune system process GO:0002683 209 0.035
positive regulation of apoptotic signaling pathway GO:2001235 95 0.034
positive regulation of hydrolase activity GO:0051345 148 0.034
positive regulation of reproductive process GO:2000243 19 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.034
telencephalon development GO:0021537 186 0.034
neuron projection extension GO:1990138 64 0.034
maternal determination of anterior posterior axis embryo GO:0008358 2 0.034
positive regulation of actin filament polymerization GO:0030838 26 0.034
protein polymerization GO:0051258 57 0.034
male courtship behavior GO:0008049 2 0.033
negative regulation of cell activation GO:0050866 111 0.033
positive regulation of cell cycle GO:0045787 92 0.033
glycerophospholipid metabolic process GO:0006650 71 0.033
regulation of neurotransmitter transport GO:0051588 35 0.033
gliogenesis GO:0042063 141 0.033
photoreceptor cell differentiation GO:0046530 52 0.033
positive regulation of binding GO:0051099 49 0.033
peptidyl threonine phosphorylation GO:0018107 31 0.033
membrane depolarization GO:0051899 64 0.033
calcium ion transport GO:0006816 159 0.033
cellular response to organonitrogen compound GO:0071417 145 0.032
regulation of calcium ion transport GO:0051924 69 0.032
vesicle localization GO:0051648 86 0.032
regulation of protein binding GO:0043393 60 0.032
positive regulation of proteolysis GO:0045862 85 0.032
positive regulation of secretion GO:0051047 130 0.032
modification dependent macromolecule catabolic process GO:0043632 133 0.032
leukocyte proliferation GO:0070661 172 0.032
immature b cell differentiation GO:0002327 10 0.032
muscle fiber development GO:0048747 76 0.032
negative regulation of epithelial cell proliferation GO:0050680 64 0.032
gland development GO:0048732 330 0.031
immune response regulating signaling pathway GO:0002764 125 0.031
exocytosis GO:0006887 121 0.031
negative regulation of cell motility GO:2000146 61 0.031
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.031
transition metal ion transport GO:0000041 38 0.031
negative regulation of wnt signaling pathway GO:0030178 73 0.031
glial cell development GO:0021782 54 0.031
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.031
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.031
regulation of mitotic cell cycle GO:0007346 126 0.031
regulation of epidermal growth factor receptor signaling pathway GO:0042058 13 0.031
peptidyl threonine modification GO:0018210 31 0.031
oxidation reduction process GO:0055114 342 0.030
protein processing GO:0016485 163 0.030
innate immune response GO:0045087 157 0.030
cytokine secretion GO:0050663 72 0.030
neuromuscular process controlling balance GO:0050885 59 0.030
regulation of protein tyrosine kinase activity GO:0061097 17 0.030
regulation of cell shape GO:0008360 39 0.030
Human
response to inactivity GO:0014854 4 0.030
positive regulation of b cell differentiation GO:0045579 13 0.030
receptor mediated endocytosis GO:0006898 51 0.030
Fly
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.030
oocyte anterior posterior axis specification GO:0007314 2 0.030
digestive tract development GO:0048565 190 0.030
regulation of neurotransmitter secretion GO:0046928 29 0.029
regulation of hormone levels GO:0010817 211 0.029
organelle fission GO:0048285 170 0.029
regulation of membrane lipid distribution GO:0097035 16 0.029
positive regulation of b cell receptor signaling pathway GO:0050861 4 0.029
detection of stimulus GO:0051606 84 0.029
cerebral cortex development GO:0021987 86 0.029
positive regulation of growth GO:0045927 104 0.029
cellular component assembly involved in morphogenesis GO:0010927 139 0.029
response to inorganic substance GO:0010035 96 0.029
phagocytosis GO:0006909 66 0.029
skeletal system development GO:0001501 356 0.029
negative regulation of monocyte extravasation GO:2000438 1 0.029
sperm individualization GO:0007291 1 0.029
leukocyte activation involved in immune response GO:0002366 126 0.028
lens development in camera type eye GO:0002088 62 0.028
feeding behavior GO:0007631 62 0.028
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.028
cyclic nucleotide metabolic process GO:0009187 59 0.028
mitochondrion organization GO:0007005 134 0.028
maintenance of location GO:0051235 89 0.027
striated muscle cell development GO:0055002 125 0.027

Sh3kbp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.120
nervous system disease DOID:863 0 0.120
neuropathy DOID:870 0 0.120
muscular disease DOID:0080000 0 0.057
musculoskeletal system disease DOID:17 0 0.057
primary immunodeficiency disease DOID:612 0 0.055
immune system disease DOID:2914 0 0.055
neuromuscular disease DOID:440 0 0.052
hematopoietic system disease DOID:74 0 0.044