|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.833
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.819
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.765
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.760
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.752
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.650
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.642
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.625
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.614
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.595
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.588
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.571
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.555
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.486
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.466
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.465
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.452
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.450
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.448
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.447
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.430
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.407
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.398
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.381
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.372
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.366
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.342
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.338
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.337
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.331
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.322
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.315
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.311
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.309
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.301
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.299
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.295
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.295
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.294
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.292
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.291
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.287
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.280
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.278
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.269
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.268
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.262
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.257
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.256
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.253
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.253
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.252
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.249
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.242
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.230
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.227
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.226
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.224
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.222
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.222
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.221
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.221
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.219
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.216
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.212
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.211
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.210
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.208
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.208
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.205
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.203
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.203
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.198
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.196
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.194
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.194
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.188
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.185
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.185
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.182
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.181
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.179
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.178
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.176
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.175
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.173
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.172
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.165
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.164
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.162
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.159
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.158
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.157
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.157
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.157
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.156
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.154
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.153
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.152
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.150
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.150
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.150
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.149
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.149
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.149
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.149
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.146
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.142
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.142
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.139
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.137
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.137
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.134
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.134
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.134
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.134
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.132
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.132
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.131
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.130
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.130
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.129
|
|
|
|
regulation of hippo signaling
|
GO:0035330 |
1 |
0.128
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.128
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.127
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.127
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.125
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.124
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.124
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.123
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.123
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.123
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.120
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.120
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.120
|
|
|
|
hippo signaling
|
GO:0035329 |
11 |
0.119
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.118
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.118
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.118
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.117
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.116
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.116
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.115
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.115
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.114
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.114
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.113
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.111
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.111
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.111
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.111
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.110
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.109
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.108
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.108
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.108
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.107
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.107
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.105
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.105
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.105
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.105
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.105
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.105
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.104
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.104
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.104
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.103
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.103
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.102
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.102
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.101
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.101
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.101
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.101
|
|
|
|
voluntary musculoskeletal movement
|
GO:0050882 |
3 |
0.100
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.100
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.099
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.097
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.096
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.096
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.096
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.095
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.095
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.095
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.095
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.094
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.093
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.092
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.092
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.092
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.092
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.091
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.091
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.091
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.090
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.090
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.089
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.089
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.088
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.088
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.087
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.087
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.087
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.086
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.085
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.085
|
Mouse |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.085
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.083
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.083
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.083
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.083
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.083
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.083
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.083
|
Mouse |
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.082
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.081
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.081
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.081
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.080
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.080
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.079
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.079
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.079
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.079
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.078
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.078
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.078
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.076
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.076
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.076
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.076
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.075
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.075
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.075
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.074
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.073
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.073
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.072
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.072
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.072
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.072
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.072
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.071
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.071
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.071
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.071
|
|
|
|
cellular response to ethanol
|
GO:0071361 |
3 |
0.071
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.071
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.071
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.071
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.070
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.070
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.070
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.069
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.069
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.068
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.068
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.068
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.067
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.066
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.066
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
4 |
0.066
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.065
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.065
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.065
|
Mouse |
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.064
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.064
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.064
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.064
|
|
|
|
regulation of synaptic transmission gabaergic
|
GO:0032228 |
17 |
0.064
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.063
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.063
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.063
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.063
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.063
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.063
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.062
|
|
|
|
adult walking behavior
|
GO:0007628 |
41 |
0.062
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.062
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.061
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.061
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.061
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.061
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.061
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.061
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.060
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.060
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.060
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.060
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.059
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.059
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.059
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.059
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.058
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.058
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.058
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
18 |
0.057
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.057
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.057
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.056
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.056
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.056
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.056
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.055
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.055
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.055
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.055
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.055
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.055
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.055
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.054
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.054
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.054
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.054
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.054
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.054
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.054
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.054
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.053
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.053
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.053
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.053
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.053
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.053
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.053
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.053
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.053
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.053
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.052
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.052
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.052
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.052
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.052
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.051
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.051
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.051
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.050
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.050
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.050
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.050
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.050
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.049
|
|
|
|
memory
|
GO:0007613 |
58 |
0.049
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.049
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.049
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.049
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.049
|
|
|
|
regulation of clathrin mediated endocytosis
|
GO:2000369 |
4 |
0.048
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.048
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.048
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.048
|
|
|
|
positive regulation of cardiac muscle contraction
|
GO:0060452 |
2 |
0.048
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.048
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.048
|
|
|
|
glucose import
|
GO:0046323 |
32 |
0.048
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.048
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.047
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.047
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.047
|
Mouse |
|
|
hormone secretion
|
GO:0046879 |
128 |
0.047
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.047
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.047
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.047
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.047
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.046
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.046
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.046
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.046
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.046
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.046
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.046
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.046
|
|
|
|
photoreceptor cell morphogenesis
|
GO:0008594 |
3 |
0.045
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.045
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.045
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.045
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.044
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.044
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.044
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.044
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.044
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.044
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.043
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.043
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.043
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.043
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.043
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.043
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.043
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.043
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.043
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.042
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.042
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.042
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.042
|
Mouse |
|
|
neural tube development
|
GO:0021915 |
160 |
0.042
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.041
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.041
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.041
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.041
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.041
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.041
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
29 |
0.041
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.041
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.040
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.040
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.040
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.040
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
3 |
0.040
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.039
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.039
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.039
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.039
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.039
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.039
|
|
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
1 |
0.039
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.039
|
|
|
|
neural retina development
|
GO:0003407 |
41 |
0.039
|
|
|
|
positive regulation of dense core granule biogenesis
|
GO:2000707 |
1 |
0.038
|
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
8 |
0.038
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.038
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.038
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.038
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.038
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.038
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.038
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.038
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.037
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
35 |
0.037
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.037
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.037
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.037
|
|
|
|
microglia development
|
GO:0014005 |
2 |
0.036
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.036
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.036
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.036
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.036
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.036
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.036
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.036
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.036
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.036
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.036
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.035
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.035
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.035
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.035
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.035
|
Mouse |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.035
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.035
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.035
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.035
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.035
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.035
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.035
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.035
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.034
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.034
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.034
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.034
|
|
|
|
iris morphogenesis
|
GO:0061072 |
2 |
0.034
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.034
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.034
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.034
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.033
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.033
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.033
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.033
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.033
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.033
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
26 |
0.033
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.033
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.033
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.033
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.033
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.032
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.032
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
3 |
0.032
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.032
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.032
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.032
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.032
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.032
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.032
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.032
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.031
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.031
|
|
|
|
histone threonine phosphorylation
|
GO:0035405 |
1 |
0.031
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.031
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.031
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.031
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.031
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.031
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.031
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.031
|
|
