Mus musculus

0 known processes

Isca1

iron-sulfur cluster assembly 1 homolog (S. cerevisiae)

(Aliases: Hbld2,1810010A06Rik)

Isca1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of mitochondrial fission GO:0090140 3 0.138
pyruvate transport GO:0006848 2 0.093
protein catabolic process GO:0030163 221 0.093
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.074
carbohydrate metabolic process GO:0005975 230 0.066
nucleobase containing small molecule metabolic process GO:0055086 352 0.065
protein modification by small protein conjugation or removal GO:0070647 207 0.060
cellular amino acid metabolic process GO:0006520 103 0.056
pyruvate metabolic process GO:0006090 28 0.054
nitrogen compound transport GO:0071705 271 0.053
apoptotic signaling pathway GO:0097190 306 0.052
cellular amine metabolic process GO:0044106 44 0.052
nucleoside metabolic process GO:0009116 246 0.050
amp metabolic process GO:0046033 4 0.048
negative regulation of cellular protein metabolic process GO:0032269 247 0.047
negative regulation of apoptotic signaling pathway GO:2001234 104 0.046
organic hydroxy compound metabolic process GO:1901615 203 0.046
regulation of apoptotic signaling pathway GO:2001233 197 0.045
translational initiation GO:0006413 24 0.045
cellular ketone metabolic process GO:0042180 84 0.045
intracellular protein transport GO:0006886 204 0.044
amine metabolic process GO:0009308 45 0.044
positive regulation of meiosis i GO:0060903 5 0.044
purine ribonucleotide metabolic process GO:0009150 290 0.044
transmembrane transport GO:0055085 412 0.043
alcohol metabolic process GO:0006066 116 0.042
intrinsic apoptotic signaling pathway GO:0097193 132 0.041
protein ubiquitination GO:0016567 171 0.039
organonitrogen compound biosynthetic process GO:1901566 192 0.039
Yeast
monocarboxylic acid metabolic process GO:0032787 191 0.038
Yeast
cellular macromolecule catabolic process GO:0044265 206 0.038
carboxylic acid biosynthetic process GO:0046394 86 0.037
Yeast
gpi anchor metabolic process GO:0006505 7 0.037
oxidation reduction process GO:0055114 342 0.035
negative regulation of phosphorus metabolic process GO:0010563 184 0.035
protein targeting GO:0006605 143 0.034
organic acid transport GO:0015849 101 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.033
mitochondrion degradation GO:0000422 3 0.033
nucleotide metabolic process GO:0009117 332 0.033
organic anion transport GO:0015711 137 0.032
regulation of membrane potential GO:0042391 192 0.031
protein modification by small protein conjugation GO:0032446 187 0.031
fat cell differentiation GO:0045444 160 0.031
regulation of transferase activity GO:0051338 263 0.030
cellular protein catabolic process GO:0044257 155 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
phospholipid metabolic process GO:0006644 87 0.029
misfolded protein transport GO:0070843 1 0.029
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.028
organic acid biosynthetic process GO:0016053 86 0.028
Yeast
anion transport GO:0006820 177 0.028
spermatogenesis GO:0007283 284 0.027
translation GO:0006412 93 0.027
macromolecule catabolic process GO:0009057 281 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
generation of precursor metabolites and energy GO:0006091 103 0.026
myeloid cell homeostasis GO:0002262 114 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
sulfur compound biosynthetic process GO:0044272 37 0.026
Yeast
regulation of cellular response to stress GO:0080135 159 0.025
proteasomal protein catabolic process GO:0010498 98 0.024
chromosome organization involved in meiosis GO:0070192 39 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
nucleoside monophosphate metabolic process GO:0009123 85 0.024
negative regulation of molecular function GO:0044092 258 0.023
transmission of nerve impulse GO:0019226 76 0.023
ion transmembrane transport GO:0034220 361 0.023
myeloid cell differentiation GO:0030099 233 0.023
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
male gamete generation GO:0048232 285 0.022
canonical wnt signaling pathway GO:0060070 130 0.022
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.022
regulation of intracellular transport GO:0032386 159 0.021
atp metabolic process GO:0046034 75 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
carboxylic acid transport GO:0046942 100 0.021
protein localization to organelle GO:0033365 185 0.021
negative regulation of protein modification process GO:0031400 163 0.020
modification dependent macromolecule catabolic process GO:0043632 133 0.020
homeostasis of number of cells GO:0048872 210 0.020
negative regulation of phosphorylation GO:0042326 166 0.019
regulation of organelle organization GO:0033043 289 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
cation homeostasis GO:0055080 212 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
negative regulation of kinase activity GO:0033673 81 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
cell maturation GO:0048469 127 0.018
negative regulation of inclusion body assembly GO:0090084 1 0.018
positive regulation of organelle organization GO:0010638 128 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
regulation of cellular ketone metabolic process GO:0010565 66 0.018
purine nucleotide metabolic process GO:0006163 302 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
peptidyl amino acid modification GO:0018193 336 0.017
erythrocyte differentiation GO:0030218 88 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
organelle fission GO:0048285 170 0.017
chiasma assembly GO:0051026 6 0.017
mitochondrion organization GO:0007005 134 0.017
regulation of protein localization GO:0032880 231 0.017
response to organonitrogen compound GO:0010243 246 0.017
translesion synthesis GO:0019985 1 0.017
dephosphorylation GO:0016311 129 0.017
acyl coa biosynthetic process GO:0071616 7 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
acetyl coa biosynthetic process GO:0006085 5 0.017
endoplasmic reticulum tubular network organization GO:0071786 1 0.017
placenta development GO:0001890 140 0.016
forebrain development GO:0030900 302 0.016
regulation of transmembrane transport GO:0034762 128 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
negative regulation of cell development GO:0010721 169 0.016
cellular homeostasis GO:0019725 240 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
protein lipidation GO:0006497 28 0.016
regulation of peptide transport GO:0090087 91 0.015
carbohydrate catabolic process GO:0016052 32 0.015
microtubule based process GO:0007017 236 0.015
thioester biosynthetic process GO:0035384 7 0.015
metal ion homeostasis GO:0055065 189 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
rna processing GO:0006396 105 0.014
purine containing compound metabolic process GO:0072521 311 0.014
regulation of secretion by cell GO:1903530 249 0.014
lipoprotein biosynthetic process GO:0042158 33 0.014
regulation of proteolysis GO:0030162 164 0.014
positive regulation of protein transport GO:0051222 93 0.014
regulation of map kinase activity GO:0043405 120 0.014
small molecule biosynthetic process GO:0044283 132 0.014
Yeast
wnt signaling pathway GO:0016055 188 0.014
endocytosis GO:0006897 168 0.014
muscle tissue development GO:0060537 308 0.014
protein maturation GO:0051604 176 0.014
regulation of inclusion body assembly GO:0090083 1 0.014
positive regulation of protein modification process GO:0031401 299 0.014
endomembrane system organization GO:0010256 147 0.014
protein folding GO:0006457 28 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
energy derivation by oxidation of organic compounds GO:0015980 77 0.014
regulation of mitochondrion organization GO:0010821 27 0.014
germ cell development GO:0007281 185 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
cellular lipid metabolic process GO:0044255 323 0.014
engulfment of apoptotic cell GO:0043652 3 0.013
response to extracellular stimulus GO:0009991 127 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
water soluble vitamin biosynthetic process GO:0042364 3 0.013
Yeast
ribonucleoside metabolic process GO:0009119 245 0.013
regulation of polyamine transmembrane transport GO:1902267 5 0.013
action potential GO:0001508 78 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
iron sulfur cluster assembly GO:0016226 3 0.013
Yeast
sulfur compound metabolic process GO:0006790 100 0.013
Yeast
mapk cascade GO:0000165 281 0.013
response to oxidative stress GO:0006979 123 0.013
dipeptide transport GO:0042938 2 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
negative regulation of camp mediated signaling GO:0043951 3 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
multicellular organismal signaling GO:0035637 91 0.013
mitochondrial transport GO:0006839 36 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
peptide transport GO:0015833 133 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
gland development GO:0048732 330 0.012
monocarboxylic acid transport GO:0015718 44 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
leukocyte differentiation GO:0002521 342 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
glycerophospholipid biosynthetic process GO:0046474 32 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
regulation of cellular amine metabolic process GO:0033238 20 0.012
hexose biosynthetic process GO:0019319 39 0.012
response to nutrient levels GO:0031667 109 0.012
lipoprotein metabolic process GO:0042157 43 0.012
regulation of hydrolase activity GO:0051336 246 0.012
lipid biosynthetic process GO:0008610 179 0.012
cofactor metabolic process GO:0051186 80 0.012
Yeast
regulation of secretion GO:0051046 274 0.012
dna endoreduplication GO:0042023 4 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.011
regulation of protein catabolic process GO:0042176 108 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
glycerolipid biosynthetic process GO:0045017 50 0.011
protein refolding GO:0042026 1 0.011
spermatid development GO:0007286 108 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
negative regulation of transferase activity GO:0051348 85 0.011
gpi anchor biosynthetic process GO:0006506 6 0.011
heterocycle catabolic process GO:0046700 280 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
protein homooligomerization GO:0051260 43 0.011
gtp metabolic process GO:0046039 144 0.011
cofactor biosynthetic process GO:0051188 41 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
regulation of homeostatic process GO:0032844 182 0.011
response to acid chemical GO:0001101 111 0.011
cardiac muscle tissue development GO:0048738 130 0.011
developmental maturation GO:0021700 193 0.011
cytoplasmic transport GO:0016482 234 0.010
ensheathment of neurons GO:0007272 76 0.010
sequestering of calcium ion GO:0051208 18 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
cell type specific apoptotic process GO:0097285 268 0.010
monocarboxylic acid biosynthetic process GO:0072330 61 0.010
Yeast
cellular modified amino acid metabolic process GO:0006575 63 0.010
ras protein signal transduction GO:0007265 77 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
organophosphate catabolic process GO:0046434 232 0.010
coenzyme biosynthetic process GO:0009108 23 0.010
stress activated protein kinase signaling cascade GO:0031098 81 0.010
multi multicellular organism process GO:0044706 109 0.010
regulation of kinase activity GO:0043549 249 0.010
myelination GO:0042552 74 0.010
nuclear transport GO:0051169 139 0.010

Isca1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.041
disease of cellular proliferation DOID:14566 0 0.041
organ system cancer DOID:0050686 0 0.041
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
nervous system disease DOID:863 0 0.012
eye disease DOID:5614 0 0.012