Mus musculus

0 known processes

Orai2

ORAI calcium release-activated calcium modulator 2

(Aliases: Tmem142b,A730041O15Rik)

Orai2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine nucleotide metabolic process GO:0006163 302 0.079
nucleoside metabolic process GO:0009116 246 0.074
organic cyclic compound catabolic process GO:1901361 295 0.071
purine ribonucleotide metabolic process GO:0009150 290 0.071
ribonucleoside triphosphate catabolic process GO:0009203 199 0.071
ras protein signal transduction GO:0007265 77 0.070
carbohydrate derivative catabolic process GO:1901136 231 0.069
nucleoside triphosphate metabolic process GO:0009141 230 0.066
nucleoside phosphate metabolic process GO:0006753 338 0.066
nucleoside catabolic process GO:0009164 206 0.065
organophosphate catabolic process GO:0046434 232 0.063
ribose phosphate metabolic process GO:0019693 291 0.062
cellular ketone metabolic process GO:0042180 84 0.062
purine ribonucleoside metabolic process GO:0046128 241 0.060
purine nucleoside catabolic process GO:0006152 205 0.060
ribonucleoside catabolic process GO:0042454 206 0.059
cellular amino acid metabolic process GO:0006520 103 0.059
organonitrogen compound catabolic process GO:1901565 264 0.059
glycosyl compound metabolic process GO:1901657 246 0.058
purine containing compound metabolic process GO:0072521 311 0.057
ribonucleoside metabolic process GO:0009119 245 0.057
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.056
glycosyl compound catabolic process GO:1901658 206 0.056
purine nucleoside metabolic process GO:0042278 241 0.056
nucleoside triphosphate catabolic process GO:0009143 205 0.055
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
purine nucleoside triphosphate metabolic process GO:0009144 226 0.054
heterocycle catabolic process GO:0046700 280 0.052
nucleoside phosphate catabolic process GO:1901292 222 0.052
purine nucleotide catabolic process GO:0006195 211 0.051
small gtpase mediated signal transduction GO:0007264 97 0.050
purine nucleoside triphosphate catabolic process GO:0009146 203 0.050
cellular amine metabolic process GO:0044106 44 0.049
cellular nitrogen compound catabolic process GO:0044270 280 0.049
regulation of hydrolase activity GO:0051336 246 0.049
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.049
nucleotide metabolic process GO:0009117 332 0.049
amine metabolic process GO:0009308 45 0.048
regulation of purine nucleotide metabolic process GO:1900542 169 0.048
ribonucleotide catabolic process GO:0009261 208 0.048
gtp metabolic process GO:0046039 144 0.048
guanosine containing compound catabolic process GO:1901069 144 0.047
positive regulation of gtpase activity GO:0043547 85 0.046
positive regulation of cellular catabolic process GO:0031331 148 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.044
purine containing compound catabolic process GO:0072523 213 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
regulation of gtp catabolic process GO:0033124 113 0.042
positive regulation of gtp catabolic process GO:0033126 85 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.042
regulation of purine nucleotide catabolic process GO:0033121 122 0.041
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
aromatic compound catabolic process GO:0019439 286 0.040
cation transport GO:0006812 399 0.039
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.039
nucleotide catabolic process GO:0009166 217 0.039
macromolecule catabolic process GO:0009057 281 0.038
positive regulation of nucleoside metabolic process GO:0045979 91 0.038
guanosine containing compound metabolic process GO:1901068 144 0.038
regulation of nucleotide metabolic process GO:0006140 169 0.038
regulation of cellular catabolic process GO:0031329 242 0.037
gtp catabolic process GO:0006184 143 0.037
negative regulation of protein metabolic process GO:0051248 282 0.035
regulation of nucleoside metabolic process GO:0009118 130 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.034
positive regulation of nucleotide metabolic process GO:0045981 114 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.032
transmembrane transport GO:0055085 412 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
regulation of nucleotide catabolic process GO:0030811 122 0.031
lymphocyte differentiation GO:0030098 242 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.031
positive regulation of nucleotide catabolic process GO:0030813 88 0.030
peptidyl amino acid modification GO:0018193 336 0.030
regulation of ras gtpase activity GO:0032318 88 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
regulation of kinase activity GO:0043549 249 0.029
positive regulation of hydrolase activity GO:0051345 148 0.029
rho protein signal transduction GO:0007266 32 0.029
cell adhesion GO:0007155 329 0.028
regulation of membrane potential GO:0042391 192 0.028
protein catabolic process GO:0030163 221 0.028
cation transmembrane transport GO:0098655 266 0.027
synaptic transmission GO:0007268 329 0.026
immune effector process GO:0002252 321 0.025
maintenance of location GO:0051235 89 0.025
ion transmembrane transport GO:0034220 361 0.025
protein maturation GO:0051604 176 0.025
regulation of lymphocyte activation GO:0051249 240 0.024
regulation of organelle organization GO:0033043 289 0.024
t cell activation GO:0042110 289 0.024
inorganic cation transmembrane transport GO:0098662 207 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
negative regulation of molecular function GO:0044092 258 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
nitrogen compound transport GO:0071705 271 0.023
leukocyte differentiation GO:0002521 342 0.023
protein processing GO:0016485 163 0.023
membrane organization GO:0061024 245 0.023
divalent inorganic cation transport GO:0072511 178 0.023
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
inflammatory response GO:0006954 244 0.022
cellular homeostasis GO:0019725 240 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
regulation of transferase activity GO:0051338 263 0.022
cellular protein complex assembly GO:0043623 116 0.022
mapk cascade GO:0000165 281 0.022
male gamete generation GO:0048232 285 0.022
organelle assembly GO:0070925 177 0.021
response to light stimulus GO:0009416 135 0.021
oxidation reduction process GO:0055114 342 0.021
sequestering of calcium ion GO:0051208 18 0.021
positive regulation of ras gtpase activity GO:0032320 65 0.021
organelle fission GO:0048285 170 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
positive regulation of cell development GO:0010720 237 0.021
homeostasis of number of cells GO:0048872 210 0.021
inorganic ion transmembrane transport GO:0098660 234 0.020
actin cytoskeleton organization GO:0030036 220 0.020
regulation of cell activation GO:0050865 289 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
cell growth GO:0016049 130 0.020
protein modification by small protein conjugation GO:0032446 187 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
positive regulation of protein modification process GO:0031401 299 0.019
positive regulation of lymphocyte activation GO:0051251 140 0.019
carbohydrate metabolic process GO:0005975 230 0.019
organelle localization GO:0051640 179 0.019
chemotaxis GO:0006935 247 0.019
endomembrane system organization GO:0010256 147 0.019
sequestering of metal ion GO:0051238 19 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
apoptotic signaling pathway GO:0097190 306 0.019
negative regulation of immune system process GO:0002683 209 0.019
regulation of protein kinase activity GO:0045859 232 0.019
t cell differentiation GO:0030217 174 0.018
response to lipopolysaccharide GO:0032496 128 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
regulation of cell projection organization GO:0031344 206 0.018
muscle cell differentiation GO:0042692 261 0.018
cellular lipid metabolic process GO:0044255 323 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
endocytosis GO:0006897 168 0.018
cellular component assembly involved in morphogenesis GO:0010927 139 0.018
dna metabolic process GO:0006259 303 0.017
spermatogenesis GO:0007283 284 0.017
intracellular protein transport GO:0006886 204 0.017
divalent metal ion transport GO:0070838 172 0.017
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.017
cell type specific apoptotic process GO:0097285 268 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
cation homeostasis GO:0055080 212 0.017
cytoplasmic transport GO:0016482 234 0.017
regulation of ion transport GO:0043269 215 0.017
negative regulation of protein modification process GO:0031400 163 0.017
cytokine production GO:0001816 319 0.017
regulation of system process GO:0044057 200 0.016
myeloid cell differentiation GO:0030099 233 0.016
protein localization to membrane GO:0072657 108 0.016
regulation of secretion GO:0051046 274 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
regulation of neuron differentiation GO:0045664 281 0.016
regulation of t cell activation GO:0050863 170 0.016
axonogenesis GO:0007409 274 0.016
leukocyte mediated immunity GO:0002443 174 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
myosin filament organization GO:0031033 3 0.015
oocyte construction GO:0007308 2 0.015
dephosphorylation GO:0016311 129 0.015
myosin filament assembly GO:0031034 2 0.015
amide transport GO:0042886 138 0.015
multicellular organismal signaling GO:0035637 91 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
glucose homeostasis GO:0042593 128 0.015
neuronal action potential GO:0019228 54 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
action potential GO:0001508 78 0.015
cellular chemical homeostasis GO:0055082 215 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
positive regulation of cell activation GO:0050867 158 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
regulation of neuron death GO:1901214 134 0.015
lipid biosynthetic process GO:0008610 179 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
phospholipid metabolic process GO:0006644 87 0.014
positive regulation of cell death GO:0010942 224 0.014
cognition GO:0050890 149 0.014
regulation of secretion by cell GO:1903530 249 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
regulation of cell growth GO:0001558 91 0.014
protein ubiquitination GO:0016567 171 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
regulation of proteolysis GO:0030162 164 0.014
negative regulation of transferase activity GO:0051348 85 0.014
response to growth factor GO:0070848 198 0.014
positive regulation of kinase activity GO:0033674 155 0.014
chromatin organization GO:0006325 206 0.014
mitotic cell cycle GO:0000278 195 0.014
regulation of homeostatic process GO:0032844 182 0.014
regulation of inflammatory response GO:0050727 147 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
oocyte axis specification GO:0007309 2 0.014
protein localization to organelle GO:0033365 185 0.014
striated muscle myosin thick filament assembly GO:0071688 1 0.014
b cell activation GO:0042113 161 0.014
blood circulation GO:0008015 195 0.014
regulation of hormone levels GO:0010817 211 0.014
nuclear division GO:0000280 158 0.013
negative regulation of kinase activity GO:0033673 81 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
regulation of anatomical structure size GO:0090066 178 0.013
carbohydrate homeostasis GO:0033500 128 0.013
adaptive immune response GO:0002250 155 0.013
transmission of nerve impulse GO:0019226 76 0.013
microtubule based process GO:0007017 236 0.013
regulation of protein processing GO:0070613 96 0.013
regulation of protein complex assembly GO:0043254 83 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of actin filament based process GO:0032970 99 0.013
histone modification GO:0016570 159 0.013
leukocyte migration GO:0050900 124 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
germ cell development GO:0007281 185 0.013
cellular response to lipid GO:0071396 145 0.013
regionalization GO:0003002 337 0.013
regulation of transmembrane transport GO:0034762 128 0.013
striated muscle cell development GO:0055002 125 0.013
regulation of neuron projection development GO:0010975 169 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
establishment of organelle localization GO:0051656 122 0.013
response to organonitrogen compound GO:0010243 246 0.013
lymphocyte proliferation GO:0046651 164 0.012
cellular protein catabolic process GO:0044257 155 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
regulation of cell cycle GO:0051726 281 0.012
neuron death GO:0070997 154 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
regulation of response to wounding GO:1903034 189 0.012
peptide transport GO:0015833 133 0.012
positive regulation of nervous system development GO:0051962 221 0.012
regulation of mapk cascade GO:0043408 248 0.012
gland development GO:0048732 330 0.012
regulation of protein maturation GO:1903317 96 0.012
calcium ion transport GO:0006816 159 0.012
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
metal ion homeostasis GO:0055065 189 0.012
positive regulation of t cell activation GO:0050870 101 0.012
plasma membrane organization GO:0007009 90 0.012
lipid localization GO:0010876 126 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
learning or memory GO:0007611 148 0.012
regulation of cytokine production GO:0001817 266 0.012
adult behavior GO:0030534 135 0.012
anatomical structure homeostasis GO:0060249 145 0.012
fertilization GO:0009566 127 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
skeletal system development GO:0001501 356 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
regulation of metal ion transport GO:0010959 106 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
single organism cell adhesion GO:0098602 156 0.012
skin development GO:0043588 220 0.011
regulation of cell adhesion GO:0030155 154 0.011
regulation of intracellular transport GO:0032386 159 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
ossification GO:0001503 216 0.011
regulation of ion transmembrane transporter activity GO:0032412 54 0.011
glycerolipid metabolic process GO:0046486 122 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
response to radiation GO:0009314 165 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
regulation of protein catabolic process GO:0042176 108 0.011
locomotory behavior GO:0007626 195 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
sensory organ morphogenesis GO:0090596 242 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
muscle cell development GO:0055001 133 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
compound eye development GO:0048749 1 0.011
activation of immune response GO:0002253 138 0.011
small molecule biosynthetic process GO:0044283 132 0.011
cell activation involved in immune response GO:0002263 126 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
mitotic cell cycle process GO:1903047 159 0.011
meiotic nuclear division GO:0007126 115 0.011
chromatin modification GO:0016568 187 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
blood vessel morphogenesis GO:0048514 285 0.011
regulation of rho gtpase activity GO:0032319 58 0.011
circulatory system process GO:0003013 197 0.011
mitotic cytokinesis GO:0000281 4 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
wound healing GO:0042060 157 0.011
glycoprotein metabolic process GO:0009100 116 0.011
developmental maturation GO:0021700 193 0.011
regulation of cellular component size GO:0032535 121 0.010
actin filament organization GO:0007015 113 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
neuron apoptotic process GO:0051402 142 0.010
regulation of protein localization GO:0032880 231 0.010
regulation of defense response GO:0031347 233 0.010
alcohol metabolic process GO:0006066 116 0.010
mitochondrion organization GO:0007005 134 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
negative regulation of protein processing GO:0010955 79 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
response to extracellular stimulus GO:0009991 127 0.010
cellular ion homeostasis GO:0006873 165 0.010
muscle tissue development GO:0060537 308 0.010
anion transport GO:0006820 177 0.010
negative regulation of cell development GO:0010721 169 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
leukocyte proliferation GO:0070661 172 0.010
positive regulation of secretion GO:0051047 130 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
response to acid chemical GO:0001101 111 0.010
meiotic cell cycle GO:0051321 122 0.010
positive regulation of cell projection organization GO:0031346 95 0.010
innate immune response GO:0045087 157 0.010
regulation of cell motility GO:2000145 236 0.010
rna processing GO:0006396 105 0.010
protein polymerization GO:0051258 57 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010
glucose metabolic process GO:0006006 92 0.010
cellular response to hormone stimulus GO:0032870 150 0.010

Orai2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.026
disease of anatomical entity DOID:7 0 0.026
disease of metabolism DOID:0014667 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
musculoskeletal system disease DOID:17 0 0.010