Mus musculus

0 known processes

Ints5

integrator complex subunit 5

(Aliases: mKIAA1698,1110055N21Rik)

Ints5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.114
oxidation reduction process GO:0055114 342 0.107
regulation of cellular ketone metabolic process GO:0010565 66 0.106
negative regulation of molecular function GO:0044092 258 0.086
regulation of organelle organization GO:0033043 289 0.082
negative regulation of protein modification process GO:0031400 163 0.067
ossification GO:0001503 216 0.065
nucleobase containing small molecule metabolic process GO:0055086 352 0.063
regulation of hydrolase activity GO:0051336 246 0.059
macromolecule catabolic process GO:0009057 281 0.058
cellular amino acid metabolic process GO:0006520 103 0.056
amine metabolic process GO:0009308 45 0.055
negative regulation of intracellular signal transduction GO:1902532 167 0.055
transmembrane transport GO:0055085 412 0.050
cellular amine metabolic process GO:0044106 44 0.050
proteasomal protein catabolic process GO:0010498 98 0.049
generation of precursor metabolites and energy GO:0006091 103 0.046
purine containing compound biosynthetic process GO:0072522 70 0.045
rhythmic process GO:0048511 174 0.045
multicellular organismal homeostasis GO:0048871 164 0.044
regulation of protein kinase activity GO:0045859 232 0.043
purine nucleotide metabolic process GO:0006163 302 0.042
protein catabolic process GO:0030163 221 0.042
leukocyte differentiation GO:0002521 342 0.042
retrograde transport endosome to golgi GO:0042147 2 0.042
metal ion homeostasis GO:0055065 189 0.040
ribonucleotide metabolic process GO:0009259 291 0.040
negative regulation of cellular amine metabolic process GO:0033239 1 0.040
positive regulation of organelle organization GO:0010638 128 0.040
protein modification by small protein conjugation or removal GO:0070647 207 0.039
dna dealkylation GO:0035510 11 0.038
cytoplasmic transport GO:0016482 234 0.037
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.037
negative regulation of protein metabolic process GO:0051248 282 0.036
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.036
positive regulation of hydrolase activity GO:0051345 148 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.036
negative regulation of phosphate metabolic process GO:0045936 184 0.035
dna metabolic process GO:0006259 303 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
purine containing compound metabolic process GO:0072521 311 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
histone methylation GO:0016571 71 0.033
cellular homeostasis GO:0019725 240 0.033
actin cytoskeleton organization GO:0030036 220 0.032
regulation of mitochondrion organization GO:0010821 27 0.032
ribose phosphate metabolic process GO:0019693 291 0.032
sensory perception GO:0007600 245 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
negative regulation of protein phosphorylation GO:0001933 126 0.031
regulation of cellular catabolic process GO:0031329 242 0.031
homeostasis of number of cells GO:0048872 210 0.031
peptidyl amino acid modification GO:0018193 336 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
negative regulation of kinase activity GO:0033673 81 0.030
negative regulation of phosphorylation GO:0042326 166 0.029
regulation of transferase activity GO:0051338 263 0.029
apoptotic signaling pathway GO:0097190 306 0.029
regulation of protein localization GO:0032880 231 0.029
cellular macromolecule catabolic process GO:0044265 206 0.028
protein targeting GO:0006605 143 0.028
negative regulation of transferase activity GO:0051348 85 0.028
signal transduction by p53 class mediator GO:0072331 51 0.028
skeletal system development GO:0001501 356 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
axonogenesis GO:0007409 274 0.027
nucleoside triphosphate metabolic process GO:0009141 230 0.027
mitochondrion organization GO:0007005 134 0.027
regulation of anatomical structure size GO:0090066 178 0.027
cation transport GO:0006812 399 0.027
development of primary sexual characteristics GO:0045137 143 0.027
myeloid cell differentiation GO:0030099 233 0.027
purine nucleoside catabolic process GO:0006152 205 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
demethylation GO:0070988 23 0.026
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
telencephalon development GO:0021537 186 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
glucose homeostasis GO:0042593 128 0.025
muscle tissue development GO:0060537 308 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
regulation of nucleoside metabolic process GO:0009118 130 0.025
cellular response to dna damage stimulus GO:0006974 207 0.024
regulation of homeostatic process GO:0032844 182 0.024
circadian regulation of gene expression GO:0032922 48 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
calcium ion homeostasis GO:0055074 127 0.024
dephosphorylation GO:0016311 129 0.024
cellular response to cytokine stimulus GO:0071345 189 0.024
tissue remodeling GO:0048771 102 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.023
cation homeostasis GO:0055080 212 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.023
regulation of neuron differentiation GO:0045664 281 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
ion transmembrane transport GO:0034220 361 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
modification dependent macromolecule catabolic process GO:0043632 133 0.022
positive regulation of protein modification process GO:0031401 299 0.021
mitotic cell cycle GO:0000278 195 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
circadian rhythm GO:0007623 114 0.021
nucleoside phosphate biosynthetic process GO:1901293 79 0.021
protein import into nucleus GO:0006606 95 0.021
tissue homeostasis GO:0001894 115 0.020
protein localization to nucleus GO:0034504 121 0.020
positive regulation of growth GO:0045927 104 0.020
multi multicellular organism process GO:0044706 109 0.020
regulation of kinase activity GO:0043549 249 0.020
regulation of cell cycle GO:0051726 281 0.020
carbohydrate homeostasis GO:0033500 128 0.020
energy derivation by oxidation of organic compounds GO:0015980 77 0.020
regulation of intracellular transport GO:0032386 159 0.020
wnt signaling pathway GO:0016055 188 0.020
camera type eye development GO:0043010 266 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
cellular protein catabolic process GO:0044257 155 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
protein ubiquitination GO:0016567 171 0.019
regulation of protein transport GO:0051223 163 0.019
endocytosis GO:0006897 168 0.019
response to light stimulus GO:0009416 135 0.019
cleavage involved in rrna processing GO:0000469 1 0.019
chemotaxis GO:0006935 247 0.019
nucleotide metabolic process GO:0009117 332 0.019
vitamin d receptor signaling pathway GO:0070561 2 0.019
positive regulation of mitochondrion organization GO:0010822 17 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
mrna metabolic process GO:0016071 84 0.018
nitrogen compound transport GO:0071705 271 0.018
purine nucleotide biosynthetic process GO:0006164 65 0.018
nuclear transport GO:0051169 139 0.018
single organism nuclear import GO:1902593 95 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
nucleobase biosynthetic process GO:0046112 3 0.018
male gamete generation GO:0048232 285 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
epithelial cell proliferation GO:0050673 174 0.018
response to organonitrogen compound GO:0010243 246 0.017
spermatogenesis GO:0007283 284 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
cell type specific apoptotic process GO:0097285 268 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
response to reactive oxygen species GO:0000302 56 0.017
regulation of histone methylation GO:0031060 30 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
maturation of ssu rrna GO:0030490 1 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
rna interference GO:0016246 2 0.017
rna processing GO:0006396 105 0.017
cellular response to external stimulus GO:0071496 88 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
regulation of protein serine threonine kinase activity GO:0071900 157 0.017
regulation of circadian rhythm GO:0042752 58 0.017
positive regulation of cell development GO:0010720 237 0.017
maintenance of location GO:0051235 89 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.016
protein localization to organelle GO:0033365 185 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
cytokine production GO:0001816 319 0.016
cellular response to extracellular stimulus GO:0031668 81 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
skeletal system morphogenesis GO:0048705 203 0.016
embryonic placenta development GO:0001892 98 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
nucleoside metabolic process GO:0009116 246 0.016
regulation of atp metabolic process GO:1903578 17 0.016
digestive tract development GO:0048565 190 0.016
response to nutrient levels GO:0031667 109 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
placenta development GO:0001890 140 0.015
protein maturation GO:0051604 176 0.015
dna modification GO:0006304 50 0.015
response to peptide GO:1901652 136 0.015
gland development GO:0048732 330 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
organ growth GO:0035265 117 0.015
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
multicellular organism growth GO:0035264 161 0.015
lipid homeostasis GO:0055088 63 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
regulation of peptidase activity GO:0052547 96 0.015
bone remodeling GO:0046849 53 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
cell cycle arrest GO:0007050 37 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
peptide transport GO:0015833 133 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
heterocycle catabolic process GO:0046700 280 0.014
purine ribonucleotide biosynthetic process GO:0009152 59 0.014
osteoclast differentiation GO:0030316 62 0.014
methylation GO:0032259 134 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
regulation of ossification GO:0030278 112 0.014
negative regulation of protein maturation GO:1903318 79 0.014
respiratory tube development GO:0030323 167 0.014
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.014
t cell differentiation GO:0030217 174 0.014
genetic imprinting GO:0071514 27 0.014
actin filament organization GO:0007015 113 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
male meiosis GO:0007140 37 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
blastocyst growth GO:0001832 23 0.014
regulation of secretion by cell GO:1903530 249 0.014
striated muscle tissue development GO:0014706 293 0.014
connective tissue development GO:0061448 179 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.013
regulation of transcription by chromatin organization GO:0034401 0 0.013
microtubule based process GO:0007017 236 0.013
histone lysine methylation GO:0034968 50 0.013
anatomical structure homeostasis GO:0060249 145 0.013
mapk cascade GO:0000165 281 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
fat cell differentiation GO:0045444 160 0.013
response to acid chemical GO:0001101 111 0.013
hexose metabolic process GO:0019318 98 0.013
response to extracellular stimulus GO:0009991 127 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
protein processing GO:0016485 163 0.013
regulation of cellular response to stress GO:0080135 159 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
divalent inorganic cation transport GO:0072511 178 0.013
regulation of myeloid leukocyte differentiation GO:0002761 58 0.013
negative regulation of growth GO:0045926 99 0.012
cell adhesion GO:0007155 329 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.012
response to oxygen levels GO:0070482 62 0.012
regulation of cellular component size GO:0032535 121 0.012
regulation of neuron projection development GO:0010975 169 0.012
regulation of generation of precursor metabolites and energy GO:0043467 38 0.012
cellular chemical homeostasis GO:0055082 215 0.012
protein oligomerization GO:0051259 67 0.012
hormone secretion GO:0046879 128 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
cellular protein complex assembly GO:0043623 116 0.012
atp metabolic process GO:0046034 75 0.012
cell activation involved in immune response GO:0002263 126 0.012
ribonucleotide biosynthetic process GO:0009260 59 0.012
regulation of ion transport GO:0043269 215 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
negative regulation of cell cycle GO:0045786 123 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
regulation of binding GO:0051098 111 0.012
forebrain development GO:0030900 302 0.012
regulation of secretion GO:0051046 274 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
monosaccharide metabolic process GO:0005996 106 0.012
positive regulation of cellular respiration GO:1901857 3 0.012
negative regulation of rna splicing GO:0033119 12 0.012
regulation of mapk cascade GO:0043408 248 0.012
regulation of proteolysis GO:0030162 164 0.012
positive regulation of phosphatase activity GO:0010922 4 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
negative regulation of ossification GO:0030279 49 0.011
positive regulation of chromosome segregation GO:0051984 4 0.011
epithelial cell development GO:0002064 159 0.011
compound eye development GO:0048749 1 0.011
innate immune response GO:0045087 157 0.011
divalent metal ion transport GO:0070838 172 0.011
multicellular organismal signaling GO:0035637 91 0.011
nuclear import GO:0051170 95 0.011
positive regulation of cell death GO:0010942 224 0.011
locomotory behavior GO:0007626 195 0.011
mammary gland epithelium development GO:0061180 65 0.011
regulation of transmembrane transport GO:0034762 128 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
b cell activation GO:0042113 161 0.011
regulation of hormone levels GO:0010817 211 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
rrna transcription GO:0009303 9 0.011
myeloid cell homeostasis GO:0002262 114 0.011
neuron death GO:0070997 154 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
germ cell development GO:0007281 185 0.011
regulation of cytokine production GO:0001817 266 0.011
macromolecule methylation GO:0043414 120 0.011
maternal process involved in female pregnancy GO:0060135 32 0.011
positive regulation of leukocyte differentiation GO:1902107 86 0.011
regulation of protein import into nucleus GO:0042306 52 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
peptide secretion GO:0002790 114 0.011
regulation of muscle tissue development GO:1901861 97 0.011
nucleoside biosynthetic process GO:0009163 21 0.011
regulation of cell motility GO:2000145 236 0.011
anion transport GO:0006820 177 0.011
ras protein signal transduction GO:0007265 77 0.011
response to radiation GO:0009314 165 0.011
t cell activation GO:0042110 289 0.011
cellular ion homeostasis GO:0006873 165 0.011
response to growth factor GO:0070848 198 0.011
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 1 0.011
regulation of feeding behavior GO:0060259 3 0.011
bone resorption GO:0045453 38 0.011
skin development GO:0043588 220 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
organic cyclic compound catabolic process GO:1901361 295 0.010
regulation of cell cycle process GO:0010564 160 0.010
stem cell differentiation GO:0048863 268 0.010
insulin secretion GO:0030073 89 0.010
cellular response to acid chemical GO:0071229 68 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
negative regulation of proteolysis GO:0045861 74 0.010
peptide hormone secretion GO:0030072 109 0.010
sensory organ morphogenesis GO:0090596 242 0.010
adult behavior GO:0030534 135 0.010
blood circulation GO:0008015 195 0.010
amide transport GO:0042886 138 0.010
endonucleolytic cleavage involved in rrna processing GO:0000478 1 0.010
energy homeostasis GO:0097009 15 0.010
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.010
negative regulation of cytokine production GO:0001818 84 0.010
response to lipopolysaccharide GO:0032496 128 0.010
ribose phosphate biosynthetic process GO:0046390 59 0.010
regulation of protein catabolic process GO:0042176 108 0.010
adaptive immune response GO:0002250 155 0.010
regulation of actin filament based process GO:0032970 99 0.010

Ints5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
gastrointestinal system cancer DOID:3119 0 0.013
intestinal cancer DOID:10155 0 0.013
large intestine cancer DOID:5672 0 0.011