Mus musculus

14 known processes

Serpina5

serine (or cysteine) peptidase inhibitor, clade A, member 5

(Aliases: Pci,4933415L04,PAI-3)

Serpina5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 284 0.341
amine metabolic process GO:0009308 45 0.317
cellular ketone metabolic process GO:0042180 84 0.305
Mouse
cellular amino acid metabolic process GO:0006520 103 0.267
apoptotic signaling pathway GO:0097190 306 0.252
regulation of mapk cascade GO:0043408 248 0.217
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.190
Mouse
positive regulation of programmed cell death GO:0043068 218 0.157
mapk cascade GO:0000165 281 0.155
Mouse
cytokine production GO:0001816 319 0.145
Mouse
positive regulation of protein modification process GO:0031401 299 0.143
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.135
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.128
positive regulation of defense response GO:0031349 124 0.128
positive regulation of protein phosphorylation GO:0001934 242 0.121
Mouse
regulation of hormone levels GO:0010817 211 0.120
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.118
macromolecule catabolic process GO:0009057 281 0.117
fertilization GO:0009566 127 0.115
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.113
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.112
Mouse
carbohydrate metabolic process GO:0005975 230 0.111
Mouse
adaptive immune response GO:0002250 155 0.109
protein processing GO:0016485 163 0.107
Mouse
cellular chemical homeostasis GO:0055082 215 0.099
leukocyte differentiation GO:0002521 342 0.097
neuron death GO:0070997 154 0.093
Mouse
inflammatory response GO:0006954 244 0.091
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.090
Mouse
male gamete generation GO:0048232 285 0.089
positive regulation of apoptotic process GO:0043065 217 0.087
cellular lipid metabolic process GO:0044255 323 0.080
Mouse
cation homeostasis GO:0055080 212 0.080
regulation of homeostatic process GO:0032844 182 0.079
nucleobase containing small molecule metabolic process GO:0055086 352 0.079
cognition GO:0050890 149 0.079
response to organonitrogen compound GO:0010243 246 0.078
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.076
negative regulation of immune system process GO:0002683 209 0.076
ribonucleotide metabolic process GO:0009259 291 0.075
circulatory system process GO:0003013 197 0.075
Mouse
response to peptide GO:1901652 136 0.074
Mouse
positive regulation of cytokine production GO:0001819 174 0.073
Mouse
glycoprotein metabolic process GO:0009100 116 0.073
Mouse
oxidation reduction process GO:0055114 342 0.073
ossification GO:0001503 216 0.072
peptidyl amino acid modification GO:0018193 336 0.070
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.066
regulation of lymphocyte activation GO:0051249 240 0.066
regulation of t cell activation GO:0050863 170 0.065
small gtpase mediated signal transduction GO:0007264 97 0.065
regulation of intracellular transport GO:0032386 159 0.064
cell type specific apoptotic process GO:0097285 268 0.063
Mouse
negative regulation of molecular function GO:0044092 258 0.063
Human Mouse
purine nucleotide metabolic process GO:0006163 302 0.062
lipid biosynthetic process GO:0008610 179 0.062
Mouse
cell cell recognition GO:0009988 44 0.062
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.062
Mouse
innate immune response GO:0045087 157 0.062
skin development GO:0043588 220 0.061
cellular response to insulin stimulus GO:0032869 78 0.061
Mouse
cellular homeostasis GO:0019725 240 0.061
regulation of cellular catabolic process GO:0031329 242 0.061
regulation of cellular amino acid metabolic process GO:0006521 5 0.060
t cell differentiation GO:0030217 174 0.060
regulation of cellular amine metabolic process GO:0033238 20 0.060
wnt signaling pathway GO:0016055 188 0.059
positive regulation of cell death GO:0010942 224 0.058
regulation of cell cycle GO:0051726 281 0.058
positive regulation of secretion GO:0051047 130 0.057
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.057
cellular amine metabolic process GO:0044106 44 0.057
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.056
regulation of proteolysis GO:0030162 164 0.056
Human Mouse
purine containing compound metabolic process GO:0072521 311 0.056
positive regulation of innate immune response GO:0045089 80 0.055
protein modification by small protein conjugation or removal GO:0070647 207 0.055
cellular metal ion homeostasis GO:0006875 151 0.054
regulation of apoptotic signaling pathway GO:2001233 197 0.053
regulation of defense response GO:0031347 233 0.053
Mouse
response to insulin GO:0032868 100 0.052
Mouse
extracellular structure organization GO:0043062 148 0.052
Mouse
skeletal system development GO:0001501 356 0.051
regulation of kinase activity GO:0043549 249 0.050
Mouse
cation transport GO:0006812 399 0.050
proteoglycan metabolic process GO:0006029 38 0.050
ras protein signal transduction GO:0007265 77 0.049
ribonucleoside metabolic process GO:0009119 245 0.049
anatomical structure homeostasis GO:0060249 145 0.047
sperm egg recognition GO:0035036 37 0.047
cellular response to cytokine stimulus GO:0071345 189 0.047
regulation of blood pressure GO:0008217 93 0.047
Mouse
response to growth factor GO:0070848 198 0.046
glucose homeostasis GO:0042593 128 0.046
protein maturation GO:0051604 176 0.046
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.046
binding of sperm to zona pellucida GO:0007339 34 0.046
regulation of leukocyte differentiation GO:1902105 159 0.045
positive regulation of immune effector process GO:0002699 107 0.045
positive regulation of cellular amine metabolic process GO:0033240 5 0.045
regulation of secretion GO:0051046 274 0.045
Mouse
regulation of cellular response to stress GO:0080135 159 0.045
nucleoside phosphate catabolic process GO:1901292 222 0.045
blood vessel morphogenesis GO:0048514 285 0.045
regulation of multi organism process GO:0043900 111 0.045
establishment of blood nerve barrier GO:0008065 3 0.044
Mouse
bone development GO:0060348 120 0.044
hormone metabolic process GO:0042445 86 0.043
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.043
protein catabolic process GO:0030163 221 0.043
cellular divalent inorganic cation homeostasis GO:0072503 127 0.043
divalent inorganic cation homeostasis GO:0072507 138 0.043
regulation of purine nucleotide metabolic process GO:1900542 169 0.042
regulation of cell activation GO:0050865 289 0.042
cellular ion homeostasis GO:0006873 165 0.042
organonitrogen compound biosynthetic process GO:1901566 192 0.041
purine containing compound biosynthetic process GO:0072522 70 0.041
cytoplasmic transport GO:0016482 234 0.040
dna metabolic process GO:0006259 303 0.040
protein localization to organelle GO:0033365 185 0.039
positive regulation of mapk cascade GO:0043410 170 0.039
Mouse
activation of immune response GO:0002253 138 0.039
response to transforming growth factor beta GO:0071559 88 0.039
bone morphogenesis GO:0060349 78 0.039
muscle cell differentiation GO:0042692 261 0.038
Mouse
myeloid cell differentiation GO:0030099 233 0.038
regulation of protein kinase activity GO:0045859 232 0.038
Mouse
regulation of vasculature development GO:1901342 88 0.038
hormone secretion GO:0046879 128 0.038
positive regulation of thymocyte migration GO:2000412 2 0.038
nucleotide metabolic process GO:0009117 332 0.037
purine ribonucleotide metabolic process GO:0009150 290 0.037
single organismal cell cell adhesion GO:0016337 131 0.037
calcium ion homeostasis GO:0055074 127 0.037
sequestering of metal ion GO:0051238 19 0.036
lymphocyte mediated immunity GO:0002449 139 0.036
endothelial cell differentiation GO:0045446 41 0.035
Mouse
negative regulation of t cell activation GO:0050868 65 0.035
epithelial tube morphogenesis GO:0060562 303 0.035
Mouse
nucleoside monophosphate metabolic process GO:0009123 85 0.035
regulation of cytokine secretion GO:0050707 61 0.035
Mouse
regulation of secretion by cell GO:1903530 249 0.035
Mouse
regulation of organelle organization GO:0033043 289 0.034
germ cell development GO:0007281 185 0.034
ribonucleotide catabolic process GO:0009261 208 0.034
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.034
blood circulation GO:0008015 195 0.034
Mouse
cytokine secretion GO:0050663 72 0.034
Mouse
cell recognition GO:0008037 83 0.034
sensory perception GO:0007600 245 0.033
single organism cell adhesion GO:0098602 156 0.033
epidermis development GO:0008544 187 0.033
negative regulation of cell activation GO:0050866 111 0.033
nucleoside metabolic process GO:0009116 246 0.033
cellular response to peptide hormone stimulus GO:0071375 92 0.033
Mouse
intestinal epithelial structure maintenance GO:0060729 4 0.033
hepaticobiliary system development GO:0061008 67 0.033
transition metal ion transport GO:0000041 38 0.033
positive regulation of protein kinase activity GO:0045860 144 0.033
Mouse
transmission of nerve impulse GO:0019226 76 0.033
insulin secretion GO:0030073 89 0.033
regulation of neuron apoptotic process GO:0043523 122 0.033
Mouse
cellular response to peptide GO:1901653 92 0.032
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.032
nitrogen compound transport GO:0071705 271 0.032
regulation of response to wounding GO:1903034 189 0.032
Mouse
negative regulation of neuron apoptotic process GO:0043524 92 0.032
Mouse
glial cell differentiation GO:0010001 131 0.032
Mouse
limb development GO:0060173 166 0.032
regulation of hydrolase activity GO:0051336 246 0.031
Human Mouse
muscle system process GO:0003012 141 0.031
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.031
Mouse
protein modification by small protein conjugation GO:0032446 187 0.031
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.031
Mouse
regulation of ion homeostasis GO:2000021 64 0.031
rhythmic process GO:0048511 174 0.031
Mouse
heterocycle catabolic process GO:0046700 280 0.031
t cell activation GO:0042110 289 0.030
sequestering of calcium ion GO:0051208 18 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
negative regulation of protein processing GO:0010955 79 0.030
Human Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.030
proton transport GO:0015992 35 0.030
lymphocyte differentiation GO:0030098 242 0.030
regulation of leukocyte proliferation GO:0070663 121 0.030
tissue homeostasis GO:0001894 115 0.030
multicellular organism growth GO:0035264 161 0.030
Mouse
positive regulation of homeostatic process GO:0032846 64 0.030
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.030
glycosyl compound metabolic process GO:1901657 246 0.030
blastocyst development GO:0001824 80 0.029
telencephalon development GO:0021537 186 0.029
negative regulation of lymphocyte activation GO:0051250 91 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.029
learning or memory GO:0007611 148 0.029
response to acid chemical GO:0001101 111 0.029
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
phospholipid metabolic process GO:0006644 87 0.028
cellular response to lipid GO:0071396 145 0.028
regulation of membrane potential GO:0042391 192 0.028
neuronal action potential GO:0019228 54 0.028
glycosylation GO:0070085 62 0.028
Mouse
regulation of protein catabolic process GO:0042176 108 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
production of molecular mediator of immune response GO:0002440 103 0.027
multicellular organismal homeostasis GO:0048871 164 0.027
response to osmotic stress GO:0006970 21 0.027
Mouse
ear development GO:0043583 200 0.027
glycoprotein biosynthetic process GO:0009101 89 0.027
Mouse
intrinsic apoptotic signaling pathway GO:0097193 132 0.027
carbohydrate homeostasis GO:0033500 128 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
glucose metabolic process GO:0006006 92 0.027
Mouse
positive regulation of t cell activation GO:0050870 101 0.027
positive regulation of lipid metabolic process GO:0045834 40 0.027
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.027
cellular response to abiotic stimulus GO:0071214 56 0.027
regulation of protein transport GO:0051223 163 0.027
Mouse
neural precursor cell proliferation GO:0061351 121 0.026
negative regulation of cell development GO:0010721 169 0.026
cellular response to gonadotropin stimulus GO:0071371 4 0.026
regulation of t cell differentiation GO:0045580 83 0.026
regulation of cytokine production GO:0001817 266 0.026
Mouse
positive regulation of transferase activity GO:0051347 167 0.026
Mouse
regulation of anatomical structure size GO:0090066 178 0.026
Mouse
action potential GO:0001508 78 0.026
negative regulation of multi organism process GO:0043901 68 0.026
negative regulation of apoptotic signaling pathway GO:2001234 104 0.026
asymmetric stem cell division GO:0098722 3 0.025
regulation of neuron death GO:1901214 134 0.025
Mouse
regulation of cell migration GO:0030334 219 0.025
camera type eye development GO:0043010 266 0.025
sulfur compound metabolic process GO:0006790 100 0.025
activation of mapk activity involved in innate immune response GO:0035419 2 0.025
regulation of map kinase activity GO:0043405 120 0.025
protein ubiquitination GO:0016567 171 0.025
male meiosis GO:0007140 37 0.025
spermatid differentiation GO:0048515 115 0.025
regulation of transferase activity GO:0051338 263 0.025
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.025
positive regulation of nucleotide metabolic process GO:0045981 114 0.025
immune response regulating signaling pathway GO:0002764 125 0.025
regulation of nucleotide metabolic process GO:0006140 169 0.024
response to molecule of bacterial origin GO:0002237 143 0.024
negative regulation of neuron death GO:1901215 98 0.024
Mouse
regulation of angiotensin metabolic process GO:0060177 4 0.024
defense response to other organism GO:0098542 197 0.024
extrinsic apoptotic signaling pathway GO:0097191 126 0.024
positive regulation of map kinase activity GO:0043406 84 0.024
cellular response to acid chemical GO:0071229 68 0.024
positive regulation of cellular catabolic process GO:0031331 148 0.024
regulation of protein serine threonine kinase activity GO:0071900 157 0.024
Mouse
regulation of eosinophil migration GO:2000416 2 0.024
cell substrate adhesion GO:0031589 130 0.024
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.024
metal ion homeostasis GO:0055065 189 0.024
molting cycle GO:0042303 90 0.023
regulation of peptidase activity GO:0052547 96 0.023
Human Mouse
morphogenesis of a branching structure GO:0001763 203 0.023
Mouse
cellular biogenic amine metabolic process GO:0006576 28 0.023
progesterone metabolic process GO:0042448 4 0.023
immune response activating signal transduction GO:0002757 116 0.023
t cell proliferation GO:0042098 120 0.023
response to radiation GO:0009314 165 0.023
mitral valve development GO:0003174 4 0.023
jnk cascade GO:0007254 72 0.023
regulation of hormone secretion GO:0046883 88 0.023
nuclear transport GO:0051169 139 0.023
wound healing GO:0042060 157 0.023
positive regulation of response to wounding GO:1903036 66 0.023
stem cell proliferation GO:0072089 117 0.022
cellular calcium ion homeostasis GO:0006874 119 0.022
regulation of lipid metabolic process GO:0019216 118 0.022
Mouse
renal system development GO:0072001 225 0.022
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
prevention of polyspermy GO:0060468 4 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
cellular response to amino acid stimulus GO:0071230 29 0.022
single fertilization GO:0007338 82 0.022
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.022
regulation of blood vessel size GO:0050880 56 0.022
Mouse
peptide secretion GO:0002790 114 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
Mouse
skeletal muscle organ development GO:0060538 163 0.021
organelle fission GO:0048285 170 0.021
hexose metabolic process GO:0019318 98 0.021
Mouse
retina development in camera type eye GO:0060041 119 0.021
cardiac ventricle development GO:0003231 83 0.021
response to lipopolysaccharide GO:0032496 128 0.021
dephosphorylation GO:0016311 129 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
regulation of thymocyte migration GO:2000410 2 0.021
rho protein signal transduction GO:0007266 32 0.021
regulation of lymphocyte differentiation GO:0045619 107 0.021
defense response to bacterium GO:0042742 119 0.021
skeletal system morphogenesis GO:0048705 203 0.021
positive regulation of cell activation GO:0050867 158 0.021
cellular response to hormone stimulus GO:0032870 150 0.020
Mouse
intracellular protein transport GO:0006886 204 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.020
striated muscle tissue development GO:0014706 293 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
b cell activation GO:0042113 161 0.020
organelle localization GO:0051640 179 0.020
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.020
Mouse
positive regulation of secretion by cell GO:1903532 114 0.020
Mouse
forebrain development GO:0030900 302 0.020
myotube differentiation GO:0014902 105 0.020
muscle tissue development GO:0060537 308 0.020
immunoglobulin mediated immune response GO:0016064 69 0.020
regulation of stress activated mapk cascade GO:0032872 69 0.020
connective tissue development GO:0061448 179 0.020
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.020
positive regulation of inflammatory response GO:0050729 47 0.020
cellular response to monosaccharide stimulus GO:0071326 47 0.019
mitotic cell cycle GO:0000278 195 0.019
ear morphogenesis GO:0042471 118 0.019
immunoglobulin production GO:0002377 73 0.019
thymocyte migration GO:0072679 2 0.019
regulation of peptide secretion GO:0002791 77 0.019
extracellular matrix organization GO:0030198 147 0.019
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
angiogenesis GO:0001525 201 0.019
endocrine process GO:0050886 39 0.019
Mouse
regulation of t cell proliferation GO:0042129 92 0.019
cell division GO:0051301 120 0.019
gonad development GO:0008406 141 0.019
Mouse
macromolecule methylation GO:0043414 120 0.019
regulation of adaptive immune response GO:0002819 90 0.019
regulation of striated muscle cell differentiation GO:0051153 81 0.019
atp metabolic process GO:0046034 75 0.019
cell maturation GO:0048469 127 0.019
peripheral nervous system development GO:0007422 53 0.019
Mouse
regulation of ion transport GO:0043269 215 0.019
nucleotide catabolic process GO:0009166 217 0.019
alcohol metabolic process GO:0006066 116 0.019
Mouse
methylation GO:0032259 134 0.019
development of primary sexual characteristics GO:0045137 143 0.019
Mouse
muscle fiber development GO:0048747 76 0.018
mitotic cell cycle process GO:1903047 159 0.018
kidney epithelium development GO:0072073 121 0.018
Mouse
purine containing compound catabolic process GO:0072523 213 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
Human Mouse
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
cofactor metabolic process GO:0051186 80 0.018
atp catabolic process GO:0006200 55 0.018
cellular response to antibiotic GO:0071236 4 0.018
organophosphate catabolic process GO:0046434 232 0.018
fat cell differentiation GO:0045444 160 0.018
pallium development GO:0021543 120 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
stress activated protein kinase signaling cascade GO:0031098 81 0.018
protein targeting GO:0006605 143 0.018
activation of mapk activity GO:0000187 59 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
myelination GO:0042552 74 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.018
Mouse
regulation of lipid biosynthetic process GO:0046890 54 0.018
Mouse
liver development GO:0001889 66 0.017
hair follicle development GO:0001942 85 0.017
response to monosaccharide GO:0034284 67 0.017
dibenzo p dioxin metabolic process GO:0018894 1 0.017
positive regulation of eosinophil migration GO:2000418 2 0.017
regionalization GO:0003002 337 0.017
endochondral bone morphogenesis GO:0060350 50 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
response to oxidative stress GO:0006979 123 0.017
b cell mediated immunity GO:0019724 71 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
regulation of nucleocytoplasmic transport GO:0046822 73 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
positive regulation of kinase activity GO:0033674 155 0.017
Mouse
positive regulation of proteolysis GO:0045862 85 0.017
carbohydrate biosynthetic process GO:0016051 74 0.017
Mouse
placenta development GO:0001890 140 0.017
jak stat cascade GO:0007259 42 0.017
response to retinoic acid GO:0032526 56 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.016
eosinophil migration GO:0072677 3 0.016
i kappab kinase nf kappab signaling GO:0007249 85 0.016
cellular response to glucose stimulus GO:0071333 45 0.016
androgen biosynthetic process GO:0006702 4 0.016
extracellular matrix dependent thymocyte migration GO:0072680 1 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
regulation of carbohydrate biosynthetic process GO:0043255 40 0.016
Mouse
leukocyte mediated immunity GO:0002443 174 0.016
cellular amide metabolic process GO:0043603 58 0.016
fibronectin dependent thymocyte migration GO:0072681 1 0.016
nuclear division GO:0000280 158 0.016
cytosolic calcium ion homeostasis GO:0051480 70 0.016
peptidyl serine modification GO:0018209 83 0.016
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
heart process GO:0003015 94 0.016
tissue regeneration GO:0042246 22 0.016
striated muscle cell development GO:0055002 125 0.016
regeneration GO:0031099 38 0.016
signal transduction in absence of ligand GO:0038034 55 0.016
regulation of protein kinase b signaling GO:0051896 56 0.016
peptide transport GO:0015833 133 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.015
aromatic compound catabolic process GO:0019439 286 0.015
kidney development GO:0001822 213 0.015
Mouse
chromatin organization GO:0006325 206 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
inner ear morphogenesis GO:0042472 101 0.015
glycerophospholipid metabolic process GO:0006650 71 0.015
activation of innate immune response GO:0002218 56 0.015
nucleoside monophosphate catabolic process GO:0009125 59 0.015
protein import GO:0017038 101 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
cartilage development GO:0051216 140 0.015
mesonephric tubule morphogenesis GO:0072171 63 0.015
Mouse
positive regulation of nervous system development GO:0051962 221 0.015
erk1 and erk2 cascade GO:0070371 77 0.015
peptide metabolic process GO:0006518 46 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.015
Mouse
endocytosis GO:0006897 168 0.015
female gamete generation GO:0007292 74 0.015
Mouse
adult locomotory behavior GO:0008344 91 0.015
macromolecule glycosylation GO:0043413 55 0.015
Mouse
acute inflammatory response GO:0002526 41 0.015
multi multicellular organism process GO:0044706 109 0.015
respiratory system development GO:0060541 190 0.015
immune effector process GO:0002252 321 0.015
negative regulation of immune effector process GO:0002698 55 0.015
face development GO:0060324 38 0.015
retina morphogenesis in camera type eye GO:0060042 45 0.015
axon ensheathment GO:0008366 76 0.015
negative regulation of response to wounding GO:1903035 77 0.014
b cell differentiation GO:0030183 78 0.014
neuron projection guidance GO:0097485 141 0.014
auditory receptor cell fate specification GO:0042667 1 0.014
cellular glucose homeostasis GO:0001678 52 0.014
negative regulation of nervous system development GO:0051961 156 0.014
positive regulation of protein catabolic process GO:0045732 60 0.014
limbic system development GO:0021761 72 0.014
cellular protein catabolic process GO:0044257 155 0.014
positive regulation of adaptive immune response GO:0002821 61 0.014
mechanoreceptor differentiation GO:0042490 67 0.014
organ growth GO:0035265 117 0.014
Mouse
establishment of protein localization to organelle GO:0072594 118 0.014
cellular response to inorganic substance GO:0071241 37 0.014
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.014
regulation of system process GO:0044057 200 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
progesterone biosynthetic process GO:0006701 1 0.014
somite development GO:0061053 81 0.013
cytokine biosynthetic process GO:0042089 68 0.013
dna recombination GO:0006310 92 0.013
proteoglycan biosynthetic process GO:0030166 20 0.013
transition metal ion homeostasis GO:0055076 54 0.013
astrocyte differentiation GO:0048708 43 0.013
Mouse
mesonephros development GO:0001823 97 0.013
Mouse
protein kinase b signaling GO:0043491 74 0.013
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.013
sodium ion transport GO:0006814 73 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
divalent metal ion transport GO:0070838 172 0.013
negative regulation of proteolysis GO:0045861 74 0.013
Human Mouse
ion transmembrane transport GO:0034220 361 0.013
ribonucleoside monophosphate catabolic process GO:0009158 57 0.013
neural tube development GO:0021915 160 0.013
response to inorganic substance GO:0010035 96 0.013
regulation of protein localization GO:0032880 231 0.013
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.013
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
protein glycosylation GO:0006486 55 0.013
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.013
odontogenesis GO:0042476 78 0.013
testosterone biosynthetic process GO:0061370 2 0.013
nucleoside catabolic process GO:0009164 206 0.013
odontogenesis of dentin containing tooth GO:0042475 66 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
negative regulation of homeostatic process GO:0032845 71 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
notch signaling pathway GO:0007219 71 0.013
lymphocyte proliferation GO:0046651 164 0.013

Serpina5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
disease of cellular proliferation DOID:14566 0 0.020
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
musculoskeletal system disease DOID:17 0 0.017
lipid metabolism disorder DOID:3146 0 0.017