Mus musculus

82 known processes

Creb5

cAMP responsive element binding protein 5

(Aliases: Crebpa,D430026C09Rik)

Creb5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.126
amine metabolic process GO:0009308 45 0.090
cellular amino acid metabolic process GO:0006520 103 0.085
purine nucleotide metabolic process GO:0006163 302 0.081
regulation of cellular ketone metabolic process GO:0010565 66 0.080
heterocycle catabolic process GO:0046700 280 0.079
nucleobase containing small molecule metabolic process GO:0055086 352 0.073
purine nucleotide catabolic process GO:0006195 211 0.069
purine containing compound metabolic process GO:0072521 311 0.066
regulation of cellular amine metabolic process GO:0033238 20 0.066
organonitrogen compound catabolic process GO:1901565 264 0.063
regulation of hydrolase activity GO:0051336 246 0.063
regulation of cellular amino acid metabolic process GO:0006521 5 0.061
nucleoside phosphate metabolic process GO:0006753 338 0.061
negative regulation of cellular protein metabolic process GO:0032269 247 0.060
Mouse
immune effector process GO:0002252 321 0.059
nucleotide metabolic process GO:0009117 332 0.059
nucleoside triphosphate metabolic process GO:0009141 230 0.057
cellular ketone metabolic process GO:0042180 84 0.057
purine ribonucleoside catabolic process GO:0046130 205 0.056
negative regulation of molecular function GO:0044092 258 0.055
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.054
organic cyclic compound catabolic process GO:1901361 295 0.053
cellular nitrogen compound catabolic process GO:0044270 280 0.053
carbohydrate derivative catabolic process GO:1901136 231 0.052
cytokine production GO:0001816 319 0.052
Mouse
ribonucleotide metabolic process GO:0009259 291 0.052
transmembrane transport GO:0055085 412 0.051
purine ribonucleotide catabolic process GO:0009154 208 0.051
cell adhesion GO:0007155 329 0.051
ion transmembrane transport GO:0034220 361 0.051
organophosphate catabolic process GO:0046434 232 0.051
ribonucleoside triphosphate catabolic process GO:0009203 199 0.050
nucleoside phosphate catabolic process GO:1901292 222 0.049
purine nucleoside triphosphate metabolic process GO:0009144 226 0.048
cation transport GO:0006812 399 0.048
aromatic compound catabolic process GO:0019439 286 0.048
purine nucleoside catabolic process GO:0006152 205 0.047
ribonucleotide catabolic process GO:0009261 208 0.046
nucleotide catabolic process GO:0009166 217 0.046
ribonucleoside triphosphate metabolic process GO:0009199 220 0.046
regulation of nucleotide metabolic process GO:0006140 169 0.046
negative regulation of protein metabolic process GO:0051248 282 0.046
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.045
peptidyl amino acid modification GO:0018193 336 0.045
cation transmembrane transport GO:0098655 266 0.045
regulation of cellular catabolic process GO:0031329 242 0.044
inorganic cation transmembrane transport GO:0098662 207 0.043
regulation of transferase activity GO:0051338 263 0.043
ribose phosphate metabolic process GO:0019693 291 0.043
purine ribonucleoside metabolic process GO:0046128 241 0.043
regulation of organelle organization GO:0033043 289 0.042
ras protein signal transduction GO:0007265 77 0.042
glycosyl compound metabolic process GO:1901657 246 0.041
inflammatory response GO:0006954 244 0.041
ribonucleoside metabolic process GO:0009119 245 0.041
macromolecule catabolic process GO:0009057 281 0.040
purine ribonucleotide metabolic process GO:0009150 290 0.040
nucleoside metabolic process GO:0009116 246 0.039
regulation of neuron differentiation GO:0045664 281 0.039
synaptic transmission GO:0007268 329 0.039
gtp catabolic process GO:0006184 143 0.039
nucleoside catabolic process GO:0009164 206 0.039
purine containing compound catabolic process GO:0072523 213 0.039
extracellular structure organization GO:0043062 148 0.039
regulation of nucleoside metabolic process GO:0009118 130 0.038
regulation of kinase activity GO:0043549 249 0.038
nucleoside triphosphate catabolic process GO:0009143 205 0.038
negative regulation of cellular amine metabolic process GO:0033239 1 0.037
positive regulation of protein modification process GO:0031401 299 0.037
regulation of defense response GO:0031347 233 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.036
glycosyl compound catabolic process GO:1901658 206 0.036
ribonucleoside catabolic process GO:0042454 206 0.036
purine nucleoside metabolic process GO:0042278 241 0.035
muscle tissue development GO:0060537 308 0.035
negative regulation of protein modification process GO:0031400 163 0.035
Mouse
regulation of response to wounding GO:1903034 189 0.035
anion transport GO:0006820 177 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.034
regulation of protein serine threonine kinase activity GO:0071900 157 0.034
negative regulation of cellular component organization GO:0051129 194 0.034
protein maturation GO:0051604 176 0.034
negative regulation of phosphorylation GO:0042326 166 0.033
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.033
cellular lipid metabolic process GO:0044255 323 0.032
divalent inorganic cation homeostasis GO:0072507 138 0.031
rho protein signal transduction GO:0007266 32 0.031
negative regulation of phosphorus metabolic process GO:0010563 184 0.031
Mouse
neuron apoptotic process GO:0051402 142 0.031
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.030
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
guanosine containing compound metabolic process GO:1901068 144 0.030
g protein coupled receptor signaling pathway GO:0007186 243 0.030
regulation of cell projection organization GO:0031344 206 0.029
inorganic ion transmembrane transport GO:0098660 234 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
organic anion transport GO:0015711 137 0.028
positive regulation of cellular catabolic process GO:0031331 148 0.028
regulation of protein kinase activity GO:0045859 232 0.028
small gtpase mediated signal transduction GO:0007264 97 0.027
cellular ion homeostasis GO:0006873 165 0.027
forebrain development GO:0030900 302 0.027
regulation of cytokine production GO:0001817 266 0.027
Mouse
protein processing GO:0016485 163 0.027
apoptotic signaling pathway GO:0097190 306 0.027
cation homeostasis GO:0055080 212 0.027
cellular homeostasis GO:0019725 240 0.026
regulation of ion transport GO:0043269 215 0.026
negative regulation of hydrolase activity GO:0051346 71 0.025
regulation of gtp catabolic process GO:0033124 113 0.025
skeletal muscle organ development GO:0060538 163 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
regulation of cell activation GO:0050865 289 0.025
regulation of anatomical structure size GO:0090066 178 0.025
mapk cascade GO:0000165 281 0.024
extracellular matrix organization GO:0030198 147 0.024
calcium ion homeostasis GO:0055074 127 0.024
gtp metabolic process GO:0046039 144 0.024
guanosine containing compound catabolic process GO:1901069 144 0.024
regulation of proteolysis GO:0030162 164 0.024
divalent inorganic cation transport GO:0072511 178 0.023
regulation of purine nucleotide catabolic process GO:0033121 122 0.023
gliogenesis GO:0042063 141 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
Mouse
fertilization GO:0009566 127 0.023
fat cell differentiation GO:0045444 160 0.023
chemotaxis GO:0006935 247 0.023
response to lipopolysaccharide GO:0032496 128 0.023
neuron death GO:0070997 154 0.023
Mouse
response to molecule of bacterial origin GO:0002237 143 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
angiogenesis GO:0001525 201 0.023
Mouse
regulation of transmembrane transport GO:0034762 128 0.022
regulation of ras gtpase activity GO:0032318 88 0.022
cognition GO:0050890 149 0.022
protein catabolic process GO:0030163 221 0.022
calcium ion transmembrane transport GO:0070588 85 0.022
cellular divalent inorganic cation homeostasis GO:0072503 127 0.022
positive regulation of cell development GO:0010720 237 0.022
metal ion homeostasis GO:0055065 189 0.022
cellular chemical homeostasis GO:0055082 215 0.021
regulation of system process GO:0044057 200 0.021
leukocyte differentiation GO:0002521 342 0.021
Mouse
regulation of cell migration GO:0030334 219 0.021
regulation of cellular component size GO:0032535 121 0.021
response to inorganic substance GO:0010035 96 0.021
Mouse
defense response to other organism GO:0098542 197 0.021
skeletal system development GO:0001501 356 0.021
membrane organization GO:0061024 245 0.020
blood vessel morphogenesis GO:0048514 285 0.020
Mouse
axonogenesis GO:0007409 274 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
regulation of homeostatic process GO:0032844 182 0.020
positive regulation of kinase activity GO:0033674 155 0.019
muscle cell differentiation GO:0042692 261 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
regulation of secretion GO:0051046 274 0.019
microtubule cytoskeleton organization GO:0000226 157 0.019
lipid transport GO:0006869 98 0.019
calcium ion transport GO:0006816 159 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.018
carboxylic acid transport GO:0046942 100 0.018
protein localization to membrane GO:0072657 108 0.018
muscle fiber development GO:0048747 76 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
developmental growth involved in morphogenesis GO:0060560 138 0.018
regulation of peptidase activity GO:0052547 96 0.018
kidney development GO:0001822 213 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
positive regulation of cytokine production GO:0001819 174 0.018
Mouse
single organism cell adhesion GO:0098602 156 0.018
positive regulation of nervous system development GO:0051962 221 0.018
single organismal cell cell adhesion GO:0016337 131 0.018
positive regulation of mapk cascade GO:0043410 170 0.018
sensory perception GO:0007600 245 0.018
cellular metal ion homeostasis GO:0006875 151 0.017
response to organic cyclic compound GO:0014070 198 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
myotube differentiation GO:0014902 105 0.017
leukocyte migration GO:0050900 124 0.017
regulation of metal ion transport GO:0010959 106 0.017
developmental maturation GO:0021700 193 0.017
neuron migration GO:0001764 122 0.017
protein ubiquitination GO:0016567 171 0.017
t cell activation GO:0042110 289 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
regulation of inflammatory response GO:0050727 147 0.017
response to oxidative stress GO:0006979 123 0.017
regulation of mapk cascade GO:0043408 248 0.017
cell type specific apoptotic process GO:0097285 268 0.017
Mouse
positive regulation of apoptotic process GO:0043065 217 0.017
positive regulation of transferase activity GO:0051347 167 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
striated muscle tissue development GO:0014706 293 0.017
positive regulation of cell death GO:0010942 224 0.017
learning or memory GO:0007611 148 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.016
divalent metal ion transport GO:0070838 172 0.016
regulation of hormone levels GO:0010817 211 0.016
stem cell differentiation GO:0048863 268 0.016
regulation of cell adhesion GO:0030155 154 0.016
oxidation reduction process GO:0055114 342 0.016
gland development GO:0048732 330 0.016
Mouse
peptidyl tyrosine modification GO:0018212 145 0.016
organelle localization GO:0051640 179 0.016
nuclear division GO:0000280 158 0.016
positive regulation of gtpase activity GO:0043547 85 0.016
wnt signaling pathway GO:0016055 188 0.016
regulation of neuron projection development GO:0010975 169 0.016
regulation of protein catabolic process GO:0042176 108 0.016
urogenital system development GO:0001655 261 0.016
regulation of cell cycle GO:0051726 281 0.016
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.016
regulation of body fluid levels GO:0050878 162 0.016
cellular response to biotic stimulus GO:0071216 92 0.016
cell recognition GO:0008037 83 0.016
regulation of reproductive process GO:2000241 66 0.016
connective tissue development GO:0061448 179 0.015
nitrogen compound transport GO:0071705 271 0.015
branching morphogenesis of an epithelial tube GO:0048754 159 0.015
sequestering of metal ion GO:0051238 19 0.015
renal system development GO:0072001 225 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
glial cell differentiation GO:0010001 131 0.015
monocarboxylic acid transport GO:0015718 44 0.015
oocyte construction GO:0007308 2 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
muscle cell development GO:0055001 133 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
response to organonitrogen compound GO:0010243 246 0.015
epithelial cell development GO:0002064 159 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
regulation of interleukin 10 secretion GO:2001179 4 0.015
negative regulation of cell development GO:0010721 169 0.015
tube closure GO:0060606 91 0.015
blood circulation GO:0008015 195 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
peptidyl tyrosine phosphorylation GO:0018108 143 0.015
negative regulation of response to wounding GO:1903035 77 0.015
regulation of synaptic plasticity GO:0048167 87 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
male gamete generation GO:0048232 285 0.015
regulation of multi organism process GO:0043900 111 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
organic acid transport GO:0015849 101 0.015
circulatory system process GO:0003013 197 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
regulation of membrane potential GO:0042391 192 0.014
ossification GO:0001503 216 0.014
Mouse
skeletal system morphogenesis GO:0048705 203 0.014
rhythmic process GO:0048511 174 0.014
cell growth GO:0016049 130 0.014
regulation of binding GO:0051098 111 0.014
oocyte axis specification GO:0007309 2 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
negative regulation of nervous system development GO:0051961 156 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
wound healing GO:0042060 157 0.014
anatomical structure homeostasis GO:0060249 145 0.014
positive regulation of immune effector process GO:0002699 107 0.014
interleukin 10 secretion GO:0072608 4 0.014
chromatin organization GO:0006325 206 0.014
positive regulation of cell activation GO:0050867 158 0.014
myeloid cell differentiation GO:0030099 233 0.014
Mouse
tissue remodeling GO:0048771 102 0.014
cell activation involved in immune response GO:0002263 126 0.014
phospholipid metabolic process GO:0006644 87 0.014
regulation of cell growth GO:0001558 91 0.014
sensory organ morphogenesis GO:0090596 242 0.014
regulation of map kinase activity GO:0043405 120 0.014
intracellular protein transport GO:0006886 204 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
microtubule based process GO:0007017 236 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
endocytosis GO:0006897 168 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
histone modification GO:0016570 159 0.013
cellular response to lipid GO:0071396 145 0.013
organelle fission GO:0048285 170 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
maintenance of location GO:0051235 89 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
dna metabolic process GO:0006259 303 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
positive regulation of neuron projection development GO:0010976 79 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
synapse organization GO:0050808 125 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
chromatin modification GO:0016568 187 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
striated muscle cell development GO:0055002 125 0.013
camera type eye development GO:0043010 266 0.013
tube formation GO:0035148 140 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
negative regulation of organelle organization GO:0010639 90 0.013
glycoprotein metabolic process GO:0009100 116 0.013
lymphocyte differentiation GO:0030098 242 0.013
cellular response to growth factor stimulus GO:0071363 197 0.012
exocytosis GO:0006887 121 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
regionalization GO:0003002 337 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
negative regulation of transferase activity GO:0051348 85 0.012
hemostasis GO:0007599 78 0.012
germ cell development GO:0007281 185 0.012
cytoplasmic transport GO:0016482 234 0.012
negative regulation of neuron death GO:1901215 98 0.012
Mouse
compound eye development GO:0048749 1 0.012
defense response to bacterium GO:0042742 119 0.012
negative regulation of kinase activity GO:0033673 81 0.012
rna processing GO:0006396 105 0.012
placenta development GO:0001890 140 0.012
Mouse
regulation of extent of cell growth GO:0061387 52 0.012
negative regulation of immune system process GO:0002683 209 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
regulation of protein processing GO:0070613 96 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
regulation of cell size GO:0008361 72 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of rho protein signal transduction GO:0035023 71 0.012
regulation of cellular response to stress GO:0080135 159 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
response to acid chemical GO:0001101 111 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
embryonic placenta development GO:0001892 98 0.011
Mouse
regulation of cell motility GO:2000145 236 0.011
dendrite development GO:0016358 115 0.011
negative regulation of endopeptidase activity GO:0010951 44 0.011
homeostasis of number of cells GO:0048872 210 0.011
asymmetric stem cell division GO:0098722 3 0.011
lipid localization GO:0010876 126 0.011
covalent chromatin modification GO:0016569 163 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
protein localization to organelle GO:0033365 185 0.011
glycerophospholipid metabolic process GO:0006650 71 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
rap protein signal transduction GO:0032486 3 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
telencephalon development GO:0021537 186 0.011
epithelial tube formation GO:0072175 130 0.011
positive regulation of neuron projection regeneration GO:0070572 2 0.011
multicellular organismal signaling GO:0035637 91 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.011
tissue homeostasis GO:0001894 115 0.011
second messenger mediated signaling GO:0019932 73 0.011
mrna metabolic process GO:0016071 84 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of myotube differentiation GO:0010830 62 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
locomotory behavior GO:0007626 195 0.011
leukocyte mediated immunity GO:0002443 174 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
regulation of secretion by cell GO:1903530 249 0.011
asymmetric neuroblast division GO:0055059 1 0.011
sensory system development GO:0048880 3 0.011
positive regulation of secretion GO:0051047 130 0.011
cell maturation GO:0048469 127 0.011
actin cytoskeleton organization GO:0030036 220 0.011
multicellular organism growth GO:0035264 161 0.010
regulation of calcium ion transport GO:0051924 69 0.010
positive regulation of proteolysis GO:0045862 85 0.010
positive regulation of ras gtpase activity GO:0032320 65 0.010
blood coagulation GO:0007596 76 0.010
negative regulation of protein maturation GO:1903318 79 0.010
spermatogenesis GO:0007283 284 0.010
cellular protein complex assembly GO:0043623 116 0.010
stem cell development GO:0048864 219 0.010
single fertilization GO:0007338 82 0.010
multicellular organismal response to stress GO:0033555 62 0.010
neuromuscular process GO:0050905 99 0.010
regulation of protein maturation GO:1903317 96 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.010
learning GO:0007612 98 0.010
regulation of neuron death GO:1901214 134 0.010
Mouse
lipid catabolic process GO:0016042 69 0.010
regulation of blood pressure GO:0008217 93 0.010
negative regulation of cell projection organization GO:0031345 56 0.010
hormone secretion GO:0046879 128 0.010
respiratory system development GO:0060541 190 0.010
regulation of protein localization GO:0032880 231 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
negative regulation of proteolysis GO:0045861 74 0.010
dephosphorylation GO:0016311 129 0.010
regulation of t cell activation GO:0050863 170 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
retina development in camera type eye GO:0060041 119 0.010
transmission of nerve impulse GO:0019226 76 0.010
innate immune response GO:0045087 157 0.010
cytosolic calcium ion homeostasis GO:0051480 70 0.010
positive regulation of leukocyte mediated immunity GO:0002705 70 0.010
negative regulation of protein processing GO:0010955 79 0.010
response to oxygen levels GO:0070482 62 0.010

Creb5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
musculoskeletal system disease DOID:17 0 0.022
disease of metabolism DOID:0014667 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
connective tissue disease DOID:65 0 0.016
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015
bone disease DOID:0080001 0 0.014
central nervous system disease DOID:331 0 0.013
neurodegenerative disease DOID:1289 0 0.011
inherited metabolic disorder DOID:655 0 0.010