Mus musculus

270 known processes

Mif

macrophage migration inhibitory factor

(Aliases: GIF,Glif,MGC107654)

Mif biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.189
regulation of cellular amino acid metabolic process GO:0006521 5 0.089
regulation of cellular ketone metabolic process GO:0010565 66 0.087
nucleobase containing small molecule metabolic process GO:0055086 352 0.076
purine containing compound metabolic process GO:0072521 311 0.075
amine metabolic process GO:0009308 45 0.071
apoptotic signaling pathway GO:0097190 306 0.064
negative regulation of protein metabolic process GO:0051248 282 0.059
cellular amine metabolic process GO:0044106 44 0.059
nucleotide metabolic process GO:0009117 332 0.057
cellular ketone metabolic process GO:0042180 84 0.055
regulation of cellular amine metabolic process GO:0033238 20 0.054
aspartate family amino acid metabolic process GO:0009066 10 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.047
cellular response to dna damage stimulus GO:0006974 207 0.045
organonitrogen compound biosynthetic process GO:1901566 192 0.045
nucleoside phosphate metabolic process GO:0006753 338 0.045
positive regulation of cellular amine metabolic process GO:0033240 5 0.045
regulation of transferase activity GO:0051338 263 0.044
macromolecule catabolic process GO:0009057 281 0.043
alpha amino acid metabolic process GO:1901605 59 0.042
organic cyclic compound catabolic process GO:1901361 295 0.041
aromatic compound catabolic process GO:0019439 286 0.040
cellular response to lipid GO:0071396 145 0.040
regulation of kinase activity GO:0043549 249 0.039
negative regulation of molecular function GO:0044092 258 0.039
defense response to other organism GO:0098542 197 0.039
spermatogenesis GO:0007283 284 0.039
regulation of apoptotic signaling pathway GO:2001233 197 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
organelle assembly GO:0070925 177 0.038
transmembrane transport GO:0055085 412 0.038
dna metabolic process GO:0006259 303 0.037
male gamete generation GO:0048232 285 0.037
single fertilization GO:0007338 82 0.037
glycosyl compound metabolic process GO:1901657 246 0.035
positive regulation of programmed cell death GO:0043068 218 0.035
nucleoside metabolic process GO:0009116 246 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.034
cellular macromolecule catabolic process GO:0044265 206 0.034
response to molecule of bacterial origin GO:0002237 143 0.034
ribonucleotide metabolic process GO:0009259 291 0.034
nucleoside phosphate catabolic process GO:1901292 222 0.034
cellular nitrogen compound catabolic process GO:0044270 280 0.034
response to organic cyclic compound GO:0014070 198 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
ribonucleoside metabolic process GO:0009119 245 0.033
fertilization GO:0009566 127 0.032
negative regulation of cell proliferation GO:0008285 296 0.032
purine nucleoside metabolic process GO:0042278 241 0.031
reactive oxygen species metabolic process GO:0072593 84 0.031
epithelial cell proliferation GO:0050673 174 0.031
protein maturation GO:0051604 176 0.030
leukocyte mediated immunity GO:0002443 174 0.030
blood vessel morphogenesis GO:0048514 285 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
single organism cell adhesion GO:0098602 156 0.029
positive regulation of cell death GO:0010942 224 0.029
response to radiation GO:0009314 165 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
carbohydrate derivative catabolic process GO:1901136 231 0.028
oxidation reduction process GO:0055114 342 0.028
cellular homeostasis GO:0019725 240 0.028
nucleoside monophosphate metabolic process GO:0009123 85 0.028
heterocycle catabolic process GO:0046700 280 0.028
muscle cell differentiation GO:0042692 261 0.027
regulation of protein localization GO:0032880 231 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
response to lipopolysaccharide GO:0032496 128 0.026
ion transmembrane transport GO:0034220 361 0.026
regulation of reactive oxygen species metabolic process GO:2000377 40 0.026
monocarboxylic acid metabolic process GO:0032787 191 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
epithelial cell development GO:0002064 159 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
positive regulation of protein modification process GO:0031401 299 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
regulation of mapk cascade GO:0043408 248 0.024
cellular response to biotic stimulus GO:0071216 92 0.024
cytoplasmic transport GO:0016482 234 0.024
sulfur compound metabolic process GO:0006790 100 0.024
intracellular protein transport GO:0006886 204 0.024
mapk cascade GO:0000165 281 0.024
blood circulation GO:0008015 195 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
protein catabolic process GO:0030163 221 0.024
protein localization to organelle GO:0033365 185 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
cellular response to lipopolysaccharide GO:0071222 77 0.023
homeostasis of number of cells GO:0048872 210 0.023
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.023
regulation of cell migration GO:0030334 219 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
maintenance of location GO:0051235 89 0.023
cellular amino acid biosynthetic process GO:0008652 22 0.023
reactive nitrogen species metabolic process GO:2001057 0 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
cellular chemical homeostasis GO:0055082 215 0.022
germ cell development GO:0007281 185 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
pole plasm assembly GO:0007315 2 0.022
carbohydrate metabolic process GO:0005975 230 0.022
regulation of peptidase activity GO:0052547 96 0.022
peptidyl amino acid modification GO:0018193 336 0.022
oocyte construction GO:0007308 2 0.021
meiotic cell cycle GO:0051321 122 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
regulation of body fluid levels GO:0050878 162 0.021
regulation of hydrolase activity GO:0051336 246 0.021
locomotory behavior GO:0007626 195 0.021
oocyte axis specification GO:0007309 2 0.021
response to organonitrogen compound GO:0010243 246 0.021
negative regulation of protein modification process GO:0031400 163 0.021
leukocyte proliferation GO:0070661 172 0.021
regulation of endopeptidase activity GO:0052548 89 0.021
methylation GO:0032259 134 0.021
regulation of protein kinase activity GO:0045859 232 0.021
gland development GO:0048732 330 0.021
meiotic nuclear division GO:0007126 115 0.021
kidney development GO:0001822 213 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
angiogenesis GO:0001525 201 0.020
cellular response to molecule of bacterial origin GO:0071219 83 0.020
mitotic cell cycle process GO:1903047 159 0.020
response to decreased oxygen levels GO:0036293 59 0.020
microtubule based process GO:0007017 236 0.020
regulation of proteolysis GO:0030162 164 0.020
membrane organization GO:0061024 245 0.020
cation transport GO:0006812 399 0.020
striated muscle cell development GO:0055002 125 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
cytokine production GO:0001816 319 0.019
cell type specific apoptotic process GO:0097285 268 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
leukocyte differentiation GO:0002521 342 0.019
regulation of cell activation GO:0050865 289 0.019
response to drug GO:0042493 75 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
ameboidal type cell migration GO:0001667 128 0.019
chromatin organization GO:0006325 206 0.019
regulation of secretion GO:0051046 274 0.018
regulation of organelle organization GO:0033043 289 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
regulation of cytokine production GO:0001817 266 0.018
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.018
innate immune response GO:0045087 157 0.018
response to oxygen levels GO:0070482 62 0.018
negative regulation of immune system process GO:0002683 209 0.018
organelle fission GO:0048285 170 0.018
negative regulation of protein maturation GO:1903318 79 0.018
striated muscle tissue development GO:0014706 293 0.017
regulation of multi organism process GO:0043900 111 0.017
ras protein signal transduction GO:0007265 77 0.017
muscle tissue development GO:0060537 308 0.017
b cell activation GO:0042113 161 0.017
cellular ion homeostasis GO:0006873 165 0.017
protein processing GO:0016485 163 0.017
regulation of cell cycle GO:0051726 281 0.017
multicellular organism growth GO:0035264 161 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
regulation of cell substrate adhesion GO:0010810 73 0.017
organophosphate catabolic process GO:0046434 232 0.017
positive regulation of cell migration GO:0030335 109 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
morphogenesis of a branching structure GO:0001763 203 0.017
negative regulation of protein processing GO:0010955 79 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
serine family amino acid metabolic process GO:0009069 7 0.017
protein ubiquitination GO:0016567 171 0.016
response to acid chemical GO:0001101 111 0.016
mitochondrion organization GO:0007005 134 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
cell recognition GO:0008037 83 0.016
telencephalon development GO:0021537 186 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
regulation of chromosome organization GO:0033044 83 0.016
coenzyme metabolic process GO:0006732 52 0.016
mitotic cell cycle GO:0000278 195 0.016
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
gonad development GO:0008406 141 0.016
renal system development GO:0072001 225 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
compound eye development GO:0048749 1 0.015
epithelium migration GO:0090132 63 0.015
oocyte anterior posterior axis specification GO:0007314 2 0.015
nucleoside phosphate biosynthetic process GO:1901293 79 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
organic acid biosynthetic process GO:0016053 86 0.015
regulation of cell cycle process GO:0010564 160 0.015
positive regulation of cell motility GO:2000147 116 0.015
regulation of neuron differentiation GO:0045664 281 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
macromolecule methylation GO:0043414 120 0.015
cell adhesion GO:0007155 329 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
circulatory system process GO:0003013 197 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
morphogenesis of a branching epithelium GO:0061138 193 0.015
regulation of protein maturation GO:1903317 96 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
mesonephric tubule development GO:0072164 94 0.015
endocytosis GO:0006897 168 0.015
male gonad development GO:0008584 88 0.015
regulation of reproductive process GO:2000241 66 0.015
camera type eye development GO:0043010 266 0.015
regionalization GO:0003002 337 0.014
negative regulation of hydrolase activity GO:0051346 71 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
intracellular mrna localization GO:0008298 4 0.014
regulation of response to wounding GO:1903034 189 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
regulation of anatomical structure size GO:0090066 178 0.014
forebrain development GO:0030900 302 0.014
lipid biosynthetic process GO:0008610 179 0.014
skeletal system morphogenesis GO:0048705 203 0.014
carbohydrate homeostasis GO:0033500 128 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
cellular protein complex assembly GO:0043623 116 0.014
negative regulation of cell development GO:0010721 169 0.014
alpha amino acid biosynthetic process GO:1901607 15 0.014
muscle cell development GO:0055001 133 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
endomembrane system organization GO:0010256 147 0.013
lateral inhibition GO:0046331 1 0.013
nucleotide catabolic process GO:0009166 217 0.013
wound healing GO:0042060 157 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
stem cell differentiation GO:0048863 268 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
positive regulation of immune effector process GO:0002699 107 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
response to ionizing radiation GO:0010212 42 0.013
anatomical structure homeostasis GO:0060249 145 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
translation GO:0006412 93 0.013
regulation of cell adhesion GO:0030155 154 0.013
regulation of ion transport GO:0043269 215 0.013
cation transmembrane transport GO:0098655 266 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
regulation of protein catabolic process GO:0042176 108 0.013
chromatin modification GO:0016568 187 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
cellular amino acid catabolic process GO:0009063 25 0.013
carboxylic acid catabolic process GO:0046395 51 0.013
ureteric bud development GO:0001657 94 0.013
organelle localization GO:0051640 179 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
cognition GO:0050890 149 0.013
myeloid cell differentiation GO:0030099 233 0.013
regulation of cell motility GO:2000145 236 0.013
positive regulation of transferase activity GO:0051347 167 0.013
regulation of translation GO:0006417 71 0.013
response to oxidative stress GO:0006979 123 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
regulation of cellular response to stress GO:0080135 159 0.013
response to extracellular stimulus GO:0009991 127 0.013
nuclear division GO:0000280 158 0.013
respiratory tube development GO:0030323 167 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
stem cell development GO:0048864 219 0.012
positive regulation of cell development GO:0010720 237 0.012
glycoprotein metabolic process GO:0009100 116 0.012
ear development GO:0043583 200 0.012
Zebrafish
modification dependent macromolecule catabolic process GO:0043632 133 0.012
neuron death GO:0070997 154 0.012
cofactor metabolic process GO:0051186 80 0.012
organic acid catabolic process GO:0016054 51 0.012
respiratory system development GO:0060541 190 0.012
chemotaxis GO:0006935 247 0.012
negative regulation of proteolysis GO:0045861 74 0.012
lymphocyte differentiation GO:0030098 242 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
sensory organ morphogenesis GO:0090596 242 0.012
purine containing compound biosynthetic process GO:0072522 70 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
axonogenesis GO:0007409 274 0.012
response to nutrient levels GO:0031667 109 0.012
response to light stimulus GO:0009416 135 0.012
multi multicellular organism process GO:0044706 109 0.012
muscle system process GO:0003012 141 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
regulation of membrane potential GO:0042391 192 0.012
purine nucleobase metabolic process GO:0006144 4 0.012
anion transport GO:0006820 177 0.012
muscle adaptation GO:0043500 39 0.012
glycosyl compound catabolic process GO:1901658 206 0.011
interspecies interaction between organisms GO:0044419 83 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
mesonephric epithelium development GO:0072163 94 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
regulation of protein processing GO:0070613 96 0.011
response to hypoxia GO:0001666 58 0.011
positive regulation of organelle organization GO:0010638 128 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
epithelial cell migration GO:0010631 63 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
myeloid cell homeostasis GO:0002262 114 0.011
regulation of hormone levels GO:0010817 211 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
mrna metabolic process GO:0016071 84 0.011
regulation of system process GO:0044057 200 0.011
myosin filament organization GO:0031033 3 0.011
hexose metabolic process GO:0019318 98 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
positive regulation of kinase activity GO:0033674 155 0.011
purine nucleobase biosynthetic process GO:0009113 3 0.011
sensory perception GO:0007600 245 0.011
steroid metabolic process GO:0008202 119 0.011
tissue migration GO:0090130 68 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
dephosphorylation GO:0016311 129 0.011
inflammatory response GO:0006954 244 0.011
glial cell differentiation GO:0010001 131 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
cation homeostasis GO:0055080 212 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
receptor mediated endocytosis GO:0006898 51 0.011
immune effector process GO:0002252 321 0.011
adaptive immune response GO:0002250 155 0.011
cell substrate adhesion GO:0031589 130 0.011
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.011
retina development in camera type eye GO:0060041 119 0.010
cellularization GO:0007349 1 0.010
purine containing compound catabolic process GO:0072523 213 0.010
nitrogen compound transport GO:0071705 271 0.010
glutamine family amino acid biosynthetic process GO:0009084 2 0.010
metal ion homeostasis GO:0055065 189 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
myosin filament assembly GO:0031034 2 0.010
protein targeting GO:0006605 143 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
response to growth factor GO:0070848 198 0.010
t cell activation GO:0042110 289 0.010
kidney epithelium development GO:0072073 121 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
protein alkylation GO:0008213 81 0.010
muscle fiber development GO:0048747 76 0.010
plasma membrane organization GO:0007009 90 0.010
purine nucleoside biosynthetic process GO:0042451 19 0.010
regulation of protein transport GO:0051223 163 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
negative regulation of nervous system development GO:0051961 156 0.010
hemostasis GO:0007599 78 0.010
fat cell differentiation GO:0045444 160 0.010
lung development GO:0030324 164 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
skeletal muscle organ development GO:0060538 163 0.010
tissue homeostasis GO:0001894 115 0.010
regulation of intracellular transport GO:0032386 159 0.010
rna interference GO:0016246 2 0.010

Mif disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.015
amino acid metabolic disorder DOID:9252 0 0.015
central nervous system disease DOID:331 0 0.012
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
immune system disease DOID:2914 0 0.011