Mus musculus

0 known processes

Fgd2

FYVE, RhoGEF and PH domain containing 2

(Aliases: ZFYVE4)

Fgd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell activation GO:0050865 289 0.103
ras protein signal transduction GO:0007265 77 0.084
cellular chemical homeostasis GO:0055082 215 0.071
regulation of lymphocyte activation GO:0051249 240 0.069
regulation of cellular ketone metabolic process GO:0010565 66 0.067
leukocyte differentiation GO:0002521 342 0.064
cytokine production GO:0001816 319 0.058
negative regulation of protein metabolic process GO:0051248 282 0.055
ion transmembrane transport GO:0034220 361 0.055
t cell activation GO:0042110 289 0.054
cellular homeostasis GO:0019725 240 0.052
reactive oxygen species metabolic process GO:0072593 84 0.051
cation transport GO:0006812 399 0.050
regulation of cellular amino acid metabolic process GO:0006521 5 0.050
myeloid cell differentiation GO:0030099 233 0.049
calcium ion transport GO:0006816 159 0.047
small gtpase mediated signal transduction GO:0007264 97 0.047
homeostasis of number of cells GO:0048872 210 0.046
transmembrane transport GO:0055085 412 0.044
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.043
response to organonitrogen compound GO:0010243 246 0.043
regulation of mapk cascade GO:0043408 248 0.043
leukocyte homeostasis GO:0001776 79 0.041
positive regulation of gtp catabolic process GO:0033126 85 0.040
regulation of system process GO:0044057 200 0.039
cell adhesion GO:0007155 329 0.038
negative regulation of cell proliferation GO:0008285 296 0.037
cation homeostasis GO:0055080 212 0.036
immune effector process GO:0002252 321 0.035
cellular ketone metabolic process GO:0042180 84 0.034
regulation of secretion GO:0051046 274 0.034
purine containing compound catabolic process GO:0072523 213 0.034
membrane organization GO:0061024 245 0.034
cellular lipid metabolic process GO:0044255 323 0.034
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.033
regulation of t cell activation GO:0050863 170 0.033
cellular amino acid metabolic process GO:0006520 103 0.033
inorganic cation transmembrane transport GO:0098662 207 0.033
mapk cascade GO:0000165 281 0.032
male gamete generation GO:0048232 285 0.032
cellular response to cytokine stimulus GO:0071345 189 0.032
muscle tissue development GO:0060537 308 0.032
regulation of cytoplasmic transport GO:1903649 112 0.032
muscle system process GO:0003012 141 0.032
b cell activation GO:0042113 161 0.032
sensory perception GO:0007600 245 0.031
cellular metal ion homeostasis GO:0006875 151 0.030
sequestering of calcium ion GO:0051208 18 0.030
peptidyl amino acid modification GO:0018193 336 0.029
leukocyte mediated immunity GO:0002443 174 0.029
carbohydrate metabolic process GO:0005975 230 0.029
negative regulation of cellular amine metabolic process GO:0033239 1 0.028
metal ion homeostasis GO:0055065 189 0.028
cellular divalent inorganic cation homeostasis GO:0072503 127 0.028
cardiac chamber development GO:0003205 108 0.028
regulation of protein kinase activity GO:0045859 232 0.028
posttranscriptional regulation of gene expression GO:0010608 155 0.027
activation of immune response GO:0002253 138 0.027
positive regulation of nervous system development GO:0051962 221 0.027
g protein coupled receptor signaling pathway GO:0007186 243 0.027
cellular calcium ion homeostasis GO:0006874 119 0.027
inflammatory response GO:0006954 244 0.027
muscle contraction GO:0006936 101 0.026
synapse organization GO:0050808 125 0.026
spermatogenesis GO:0007283 284 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
myeloid leukocyte activation GO:0002274 83 0.026
cation transmembrane transport GO:0098655 266 0.026
positive regulation of cellular catabolic process GO:0031331 148 0.026
monocarboxylic acid metabolic process GO:0032787 191 0.026
cognition GO:0050890 149 0.025
hematopoietic progenitor cell differentiation GO:0002244 143 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
regulation of membrane potential GO:0042391 192 0.025
cellular component assembly involved in morphogenesis GO:0010927 139 0.025
divalent metal ion transport GO:0070838 172 0.025
maintenance of location GO:0051235 89 0.025
calcium ion homeostasis GO:0055074 127 0.025
cell substrate adhesion GO:0031589 130 0.025
axonogenesis GO:0007409 274 0.024
cellular ion homeostasis GO:0006873 165 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
amine metabolic process GO:0009308 45 0.024
sequestering of metal ion GO:0051238 19 0.024
chemotaxis GO:0006935 247 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
negative regulation of protein modification process GO:0031400 163 0.023
innate immune response GO:0045087 157 0.023
regulation of transferase activity GO:0051338 263 0.023
circulatory system process GO:0003013 197 0.023
regulation of ion transport GO:0043269 215 0.023
positive regulation of cytokine production GO:0001819 174 0.022
nucleotide metabolic process GO:0009117 332 0.022
renal system development GO:0072001 225 0.022
heart morphogenesis GO:0003007 178 0.022
rho protein signal transduction GO:0007266 32 0.022
actin cytoskeleton organization GO:0030036 220 0.022
nitrogen compound transport GO:0071705 271 0.022
negative regulation of immune system process GO:0002683 209 0.022
cellular amine metabolic process GO:0044106 44 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.022
myeloid leukocyte differentiation GO:0002573 119 0.021
divalent inorganic cation transport GO:0072511 178 0.021
cytoplasmic transport GO:0016482 234 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
glycerolipid metabolic process GO:0046486 122 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
immune response activating signal transduction GO:0002757 116 0.021
multicellular organismal signaling GO:0035637 91 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
regulation of hydrolase activity GO:0051336 246 0.021
regulation of myeloid cell differentiation GO:0045637 96 0.021
cellular response to peptide GO:1901653 92 0.020
cell type specific apoptotic process GO:0097285 268 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.020
striated muscle contraction GO:0006941 45 0.020
learning or memory GO:0007611 148 0.020
response to peptide hormone GO:0043434 127 0.020
regulation of blood circulation GO:1903522 93 0.020
positive regulation of t cell activation GO:0050870 101 0.020
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
digestive system development GO:0055123 200 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
purine containing compound metabolic process GO:0072521 311 0.020
regulation of secretion by cell GO:1903530 249 0.019
regulation of organelle organization GO:0033043 289 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
regulation of cytokine production GO:0001817 266 0.019
striated muscle tissue development GO:0014706 293 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
organelle assembly GO:0070925 177 0.019
positive regulation of transferase activity GO:0051347 167 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
endomembrane system organization GO:0010256 147 0.019
regulation of kinase activity GO:0043549 249 0.019
regulation of innate immune response GO:0045088 91 0.019
heart process GO:0003015 94 0.019
protein catabolic process GO:0030163 221 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
adaptive immune response GO:0002250 155 0.019
response to oxidative stress GO:0006979 123 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
positive regulation of kinase activity GO:0033674 155 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
regulation of cell adhesion GO:0030155 154 0.018
response to extracellular stimulus GO:0009991 127 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
positive regulation of protein modification process GO:0031401 299 0.018
b cell homeostasis GO:0001782 34 0.018
hemostasis GO:0007599 78 0.018
gland development GO:0048732 330 0.018
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 17 0.018
response to organic cyclic compound GO:0014070 198 0.018
carbohydrate homeostasis GO:0033500 128 0.018
calcium ion transport into cytosol GO:0060402 48 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.017
camera type eye development GO:0043010 266 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
regulation of muscle system process GO:0090257 80 0.017
positive regulation of cell death GO:0010942 224 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
cell activation involved in immune response GO:0002263 126 0.017
negative regulation of molecular function GO:0044092 258 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.017
urogenital system development GO:0001655 261 0.017
response to peptide GO:1901652 136 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
positive regulation of cell migration GO:0030335 109 0.017
regulation of map kinase activity GO:0043405 120 0.017
heterocycle catabolic process GO:0046700 280 0.017
glucose homeostasis GO:0042593 128 0.017
response to lipopolysaccharide GO:0032496 128 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
ear development GO:0043583 200 0.017
protein ubiquitination GO:0016567 171 0.017
epithelial cell development GO:0002064 159 0.016
Worm
purine nucleoside metabolic process GO:0042278 241 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
positive regulation of cell development GO:0010720 237 0.016
cellular response to biotic stimulus GO:0071216 92 0.016
methylation GO:0032259 134 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
positive regulation of cell motility GO:2000147 116 0.016
response to transforming growth factor beta GO:0071559 88 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
germ cell development GO:0007281 185 0.016
actin filament based movement GO:0030048 23 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
respiratory system development GO:0060541 190 0.016
regulation of cell migration GO:0030334 219 0.016
regulation of cell projection organization GO:0031344 206 0.016
tissue homeostasis GO:0001894 115 0.016
regulation of anatomical structure size GO:0090066 178 0.016
Worm
regulation of lipid metabolic process GO:0019216 118 0.015
aromatic compound catabolic process GO:0019439 286 0.015
cardiac ventricle development GO:0003231 83 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
intestinal epithelial structure maintenance GO:0060729 4 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
b cell mediated immunity GO:0019724 71 0.015
nucleotide catabolic process GO:0009166 217 0.015
learning GO:0007612 98 0.015
spermatid development GO:0007286 108 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
regulation of homeostatic process GO:0032844 182 0.015
regulation of intracellular transport GO:0032386 159 0.015
lymphocyte proliferation GO:0046651 164 0.015
response to growth factor GO:0070848 198 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
anatomical structure homeostasis GO:0060249 145 0.015
glycoprotein metabolic process GO:0009100 116 0.015
skeletal system development GO:0001501 356 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
regulation of vesicle mediated transport GO:0060627 139 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
cellular protein complex assembly GO:0043623 116 0.014
oxidation reduction process GO:0055114 342 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
regulation of neuron differentiation GO:0045664 281 0.014
tube formation GO:0035148 140 0.014
establishment of vesicle localization GO:0051650 81 0.014
interleukin 6 production GO:0032635 58 0.014
transmission of nerve impulse GO:0019226 76 0.014
lymphocyte homeostasis GO:0002260 64 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
lymphocyte differentiation GO:0030098 242 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
germinal center formation GO:0002467 16 0.014
hormone secretion GO:0046879 128 0.014
regulation of hormone levels GO:0010817 211 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
oocyte axis specification GO:0007309 2 0.014
gonad development GO:0008406 141 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.014
negative regulation of synapse assembly GO:0051964 3 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
response to insulin GO:0032868 100 0.013
cytokine mediated signaling pathway GO:0019221 115 0.013
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.013
locomotory behavior GO:0007626 195 0.013
rac protein signal transduction GO:0016601 13 0.013
macromolecule catabolic process GO:0009057 281 0.013
regulation of cell cycle process GO:0010564 160 0.013
neural tube development GO:0021915 160 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
positive regulation of vasoconstriction GO:0045907 4 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
cytosolic calcium ion homeostasis GO:0051480 70 0.013
nucleoside catabolic process GO:0009164 206 0.013
tendon cell differentiation GO:0035990 4 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
microtubule based process GO:0007017 236 0.013
response to radiation GO:0009314 165 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
leukocyte proliferation GO:0070661 172 0.013
leukocyte migration GO:0050900 124 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
gtp catabolic process GO:0006184 143 0.013
apoptotic signaling pathway GO:0097190 306 0.013
multicellular organism growth GO:0035264 161 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
leukocyte chemotaxis GO:0030595 69 0.013
antigen processing and presentation of exogenous antigen GO:0019884 26 0.013
regulation of protein secretion GO:0050708 82 0.013
asymmetric stem cell division GO:0098722 3 0.013
heart contraction GO:0060047 93 0.013
vesicle localization GO:0051648 86 0.013
epithelial cell proliferation GO:0050673 174 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
intracellular protein transport GO:0006886 204 0.012
cardiac muscle tissue development GO:0048738 130 0.012
regulation of b cell activation GO:0050864 81 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
response to nutrient levels GO:0031667 109 0.012
mesoderm development GO:0007498 100 0.012
oocyte construction GO:0007308 2 0.012
toll like receptor 9 signaling pathway GO:0034162 6 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
regulation of body fluid levels GO:0050878 162 0.012
cellular response to lipid GO:0071396 145 0.012
cardiocyte differentiation GO:0035051 87 0.012
regulation of cell motility GO:2000145 236 0.012
sensory organ morphogenesis GO:0090596 242 0.012
regulation of cell cycle GO:0051726 281 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
antigen receptor mediated signaling pathway GO:0050851 64 0.012
regulation of adaptive immune response GO:0002819 90 0.012
regulation of transmembrane transport GO:0034762 128 0.012
glial cell differentiation GO:0010001 131 0.012
superoxide metabolic process GO:0006801 27 0.012
dna metabolic process GO:0006259 303 0.012
organophosphate catabolic process GO:0046434 232 0.012
response to inorganic substance GO:0010035 96 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
regulation of metal ion transport GO:0010959 106 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
mesodermal cell migration GO:0008078 4 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.012
kidney development GO:0001822 213 0.012
fertilization GO:0009566 127 0.012
cytosolic calcium ion transport GO:0060401 48 0.012
action potential GO:0001508 78 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
innate immune response activating signal transduction GO:0002758 50 0.012
endocytosis GO:0006897 168 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
macromolecule methylation GO:0043414 120 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
cerebellar cortex development GO:0021695 48 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
organic anion transport GO:0015711 137 0.011
forebrain development GO:0030900 302 0.011
dendrite development GO:0016358 115 0.011
humoral immune response GO:0006959 57 0.011
regulation of natural killer cell activation GO:0032814 22 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
neuronal action potential GO:0019228 54 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
mature dendritic cell differentiation GO:0097029 3 0.011
spermatid differentiation GO:0048515 115 0.011
positive regulation of b cell activation GO:0050871 49 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
mitochondrion distribution GO:0048311 4 0.011
myeloid leukocyte mediated immunity GO:0002444 42 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
lateral inhibition GO:0046331 1 0.011
antigen processing and presentation of peptide antigen GO:0048002 29 0.011
phospholipid metabolic process GO:0006644 87 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
regulation of neuron projection development GO:0010975 169 0.011
compound eye development GO:0048749 1 0.011
primary neural tube formation GO:0014020 95 0.011
nuclear division GO:0000280 158 0.011
bone resorption GO:0045453 38 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of erk1 and erk2 cascade GO:0070372 71 0.011
neuron apoptotic process GO:0051402 142 0.011
macromolecule glycosylation GO:0043413 55 0.011
skin development GO:0043588 220 0.011
defense response to bacterium GO:0042742 119 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.011
protein glycosylation GO:0006486 55 0.011
activation of innate immune response GO:0002218 56 0.011
regulation of protein localization GO:0032880 231 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
cellular response to oxidative stress GO:0034599 76 0.010
b cell proliferation GO:0042100 53 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
positive regulation of adaptive immune response GO:0002821 61 0.010
sulfur compound metabolic process GO:0006790 100 0.010
regulation of cellular response to stress GO:0080135 159 0.010
connective tissue development GO:0061448 179 0.010
positive regulation of secretion GO:0051047 130 0.010
bmp signaling pathway GO:0030509 93 0.010
cell chemotaxis GO:0060326 81 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.010
positive regulation of neuron projection development GO:0010976 79 0.010
ribonucleotide metabolic process GO:0009259 291 0.010
stem cell proliferation GO:0072089 117 0.010
gastrulation GO:0007369 116 0.010
response to light stimulus GO:0009416 135 0.010
erythrocyte differentiation GO:0030218 88 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
t cell receptor signaling pathway GO:0050852 46 0.010
cell fate commitment GO:0045165 210 0.010
t cell differentiation GO:0030217 174 0.010
negative regulation of cell activation GO:0050866 111 0.010

Fgd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015