Mus musculus

133 known processes

Il1a

interleukin 1 alpha

(Aliases: Il-1a)

Il1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to lipopolysaccharide GO:0071222 77 0.879
regulation of inflammatory response GO:0050727 147 0.827
Mouse
cellular response to biotic stimulus GO:0071216 92 0.705
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.666
response to molecule of bacterial origin GO:0002237 143 0.661
Zebrafish Mouse
monocyte chemotactic protein 1 production GO:0071605 1 0.655
reactive nitrogen species metabolic process GO:2001057 0 0.654
myeloid cell differentiation GO:0030099 233 0.649
inflammatory response GO:0006954 244 0.589
defense response to bacterium GO:0042742 119 0.587
Zebrafish
positive regulation of cytokine production GO:0001819 174 0.578
granulocyte migration GO:0097530 43 0.566
Mouse
regulation of cell activation GO:0050865 289 0.564
cellular response to lipid GO:0071396 145 0.547
cellular response to molecule of bacterial origin GO:0071219 83 0.546
adiponectin secretion GO:0070162 2 0.544
Mouse
inflammatory response to wounding GO:0090594 4 0.514
fat soluble vitamin biosynthetic process GO:0042362 4 0.496
myeloid leukocyte differentiation GO:0002573 119 0.488
cell chemotaxis GO:0060326 81 0.471
Mouse
myeloid leukocyte migration GO:0097529 57 0.462
Mouse
chemotaxis GO:0006935 247 0.457
Mouse
regulation of response to wounding GO:1903034 189 0.446
Mouse
response to arsenic containing substance GO:0046685 5 0.442
Zebrafish
response to lipopolysaccharide GO:0032496 128 0.441
Zebrafish Mouse
regulation of acute inflammatory response GO:0002673 27 0.439
Mouse
single organism cell adhesion GO:0098602 156 0.439
regulation of defense response GO:0031347 233 0.436
Mouse
single organismal cell cell adhesion GO:0016337 131 0.433
leukocyte chemotaxis GO:0030595 69 0.424
Mouse
positive regulation of angiogenesis GO:0045766 46 0.416
defense response to other organism GO:0098542 197 0.403
Zebrafish
t cell proliferation GO:0042098 120 0.400
response to atp GO:0033198 8 0.398
Mouse
neutrophil migration GO:1990266 37 0.398
Mouse
neutrophil chemotaxis GO:0030593 36 0.397
Mouse
apoptotic signaling pathway GO:0097190 306 0.385
mapk cascade GO:0000165 281 0.383
Mouse
vitamin d biosynthetic process GO:0042368 3 0.382
negative regulation of lipid metabolic process GO:0045833 30 0.372
Mouse
wound healing involved in inflammatory response GO:0002246 4 0.367
regulation of cytokine production GO:0001817 266 0.367
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.366
protein catabolic process GO:0030163 221 0.360
positive regulation of lipid catabolic process GO:0050996 6 0.359
Mouse
positive regulation of cell motility GO:2000147 116 0.354
response to organic cyclic compound GO:0014070 198 0.353
Zebrafish Mouse
regulation of t cell activation GO:0050863 170 0.345
macromolecule catabolic process GO:0009057 281 0.341
leukocyte apoptotic process GO:0071887 71 0.340
positive regulation of programmed cell death GO:0043068 218 0.331
leukocyte migration GO:0050900 124 0.330
Mouse
regulation of chemotaxis GO:0050920 53 0.330
keratinocyte migration GO:0051546 3 0.326
regulation of lymphocyte activation GO:0051249 240 0.326
cellular ketone metabolic process GO:0042180 84 0.321
granulocyte chemotaxis GO:0071621 39 0.317
Mouse
positive regulation of cell activation GO:0050867 158 0.317
cytokine production GO:0001816 319 0.314
positive regulation of defense response GO:0031349 124 0.312
Mouse
regulation of adiponectin secretion GO:0070163 2 0.310
Mouse
wound healing GO:0042060 157 0.300
regulation of cellular catabolic process GO:0031329 242 0.289
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.285
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.281
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.279
anion transport GO:0006820 177 0.278
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.277
Mouse
regulation of lipid catabolic process GO:0050994 15 0.277
Mouse
activation of immune response GO:0002253 138 0.277
alcohol metabolic process GO:0006066 116 0.276
leukocyte homeostasis GO:0001776 79 0.274
leukocyte differentiation GO:0002521 342 0.274
positive regulation of cellular catabolic process GO:0031331 148 0.263
t cell activation GO:0042110 289 0.261
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.259
nik nf kappab signaling GO:0038061 14 0.256
Zebrafish
gland development GO:0048732 330 0.256
positive regulation of lipid metabolic process GO:0045834 40 0.256
Mouse
leukocyte proliferation GO:0070661 172 0.255
negative regulation of map kinase activity GO:0043407 34 0.253
Mouse
signal transduction in absence of ligand GO:0038034 55 0.253
regulation of interleukin 8 production GO:0032677 3 0.252
regulation of monocyte chemotaxis GO:0090025 3 0.252
positive regulation of immune effector process GO:0002699 107 0.251
regulation of proteolysis GO:0030162 164 0.247
detection of fungus GO:0016046 2 0.242
regulation of mapk cascade GO:0043408 248 0.238
Mouse
regulation of vascular endothelial growth factor production GO:0010574 13 0.237
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.237
regulation of steroid biosynthetic process GO:0050810 26 0.237
response to organophosphorus GO:0046683 22 0.236
Mouse
cytokine metabolic process GO:0042107 71 0.235
Human Mouse
regulation of leukocyte apoptotic process GO:2000106 56 0.230
response to organonitrogen compound GO:0010243 246 0.226
Mouse
positive regulation of monocyte chemotaxis GO:0090026 2 0.226
defense response to gram positive bacterium GO:0050830 50 0.223
leukocyte cell cell adhesion GO:0007159 14 0.220
regulation of cell migration GO:0030334 219 0.220
innate immune response GO:0045087 157 0.219
positive regulation of lipid transport GO:0032370 22 0.219
Mouse
positive regulation of transferase activity GO:0051347 167 0.218
protein kinase b signaling GO:0043491 74 0.217
steroid metabolic process GO:0008202 119 0.213
regulation of reactive oxygen species metabolic process GO:2000377 40 0.210
rho protein signal transduction GO:0007266 32 0.209
regulation of lymphocyte proliferation GO:0050670 117 0.205
positive regulation of cell migration GO:0030335 109 0.205
regulation of vasculature development GO:1901342 88 0.205
positive regulation of t cell activation GO:0050870 101 0.205
regulation of insulin receptor signaling pathway GO:0046626 21 0.202
Mouse
cytokine secretion GO:0050663 72 0.201
Human
vitamin metabolic process GO:0006766 23 0.201
lipid biosynthetic process GO:0008610 179 0.200
jnk cascade GO:0007254 72 0.200
Mouse
lymphocyte proliferation GO:0046651 164 0.198
leukocyte activation involved in immune response GO:0002366 126 0.197
regulation of transferase activity GO:0051338 263 0.195
Mouse
acute inflammatory response GO:0002526 41 0.193
Mouse
positive regulation of chemokine biosynthetic process GO:0045080 6 0.192
Mouse
amine metabolic process GO:0009308 45 0.189
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.189
negative regulation of protein modification process GO:0031400 163 0.188
Mouse
regulation of t cell proliferation GO:0042129 92 0.186
positive regulation of kinase activity GO:0033674 155 0.186
cellular response to cytokine stimulus GO:0071345 189 0.185
Human
regulation of hydrolase activity GO:0051336 246 0.185
organic anion transport GO:0015711 137 0.184
Mouse
carboxylic acid transport GO:0046942 100 0.183
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.182
small molecule biosynthetic process GO:0044283 132 0.182
interleukin 2 biosynthetic process GO:0042094 15 0.181
Human
regulation of secretion GO:0051046 274 0.180
Human Mouse
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.179
homeostasis of number of cells GO:0048872 210 0.179
regulation of innate immune response GO:0045088 91 0.179
protein maturation GO:0051604 176 0.177
positive regulation of protein modification process GO:0031401 299 0.176
positive regulation of protein kinase activity GO:0045860 144 0.176
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.176
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.174
regulation of cellular ketone metabolic process GO:0010565 66 0.172
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.172
g protein coupled receptor signaling pathway GO:0007186 243 0.171
mature dendritic cell differentiation GO:0097029 3 0.170
positive regulation of cytokine biosynthetic process GO:0042108 40 0.169
Human Mouse
positive regulation of proteolysis GO:0045862 85 0.168
blood coagulation GO:0007596 76 0.168
activation of innate immune response GO:0002218 56 0.168
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.167
regulation of interleukin 2 production GO:0032663 28 0.165
Human
reactive oxygen species metabolic process GO:0072593 84 0.165
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.160
organic hydroxy compound metabolic process GO:1901615 203 0.160
cellular amino acid metabolic process GO:0006520 103 0.159
regulation of cellular response to stress GO:0080135 159 0.157
Mouse
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.157
negative regulation of protein processing GO:0010955 79 0.157
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.156
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.156
positive regulation of interferon gamma production GO:0032729 39 0.156
negative regulation of secretion GO:0051048 61 0.156
Mouse
positive regulation of innate immune response GO:0045089 80 0.155
regulation of interferon gamma production GO:0032649 57 0.155
cellular homeostasis GO:0019725 240 0.155
regulation of stress activated mapk cascade GO:0032872 69 0.154
Mouse
positive regulation of map kinase activity GO:0043406 84 0.153
vascular endothelial growth factor production GO:0010573 13 0.152
positive regulation of granulocyte chemotaxis GO:0071624 12 0.152
cellular response to organic cyclic compound GO:0071407 87 0.151
steroid biosynthetic process GO:0006694 47 0.151
extrinsic apoptotic signaling pathway GO:0097191 126 0.150
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.150
cellular chemical homeostasis GO:0055082 215 0.150
regulation of jnk cascade GO:0046328 62 0.149
Mouse
positive regulation of leukocyte proliferation GO:0070665 73 0.147
positive regulation of macrophage chemotaxis GO:0010759 5 0.147
regulation of lipid metabolic process GO:0019216 118 0.147
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.143
Mouse
regulation of hormone levels GO:0010817 211 0.142
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.141
Human Mouse
nucleotide catabolic process GO:0009166 217 0.139
negative regulation of macrophage apoptotic process GO:2000110 3 0.138
regulation of protein serine threonine kinase activity GO:0071900 157 0.136
Mouse
regulation of map kinase activity GO:0043405 120 0.136
Mouse
dendritic cell differentiation GO:0097028 26 0.136
nitrogen compound transport GO:0071705 271 0.136
Mouse
positive regulation of neutrophil chemotaxis GO:0090023 12 0.135
regulation of protein processing GO:0070613 96 0.135
cellular amine metabolic process GO:0044106 44 0.135
maintenance of location GO:0051235 89 0.135
positive regulation of secretion by cell GO:1903532 114 0.135
Human
positive regulation of protein phosphorylation GO:0001934 242 0.134
regulation of hemostasis GO:1900046 28 0.133
positive regulation of lymphocyte proliferation GO:0050671 70 0.132
alcohol biosynthetic process GO:0046165 43 0.132
chemokine metabolic process GO:0050755 10 0.130
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.128
Mouse
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.128
regulation of muscle tissue development GO:1901861 97 0.127
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.126
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.126
cell activation involved in immune response GO:0002263 126 0.126
positive regulation of acute inflammatory response GO:0002675 16 0.126
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.124
regulation of cell motility GO:2000145 236 0.124
response to purine containing compound GO:0014074 28 0.124
Mouse
stress activated protein kinase signaling cascade GO:0031098 81 0.123
Mouse
positive regulation of fatty acid transport GO:2000193 8 0.122
Mouse
negative regulation of myoblast differentiation GO:0045662 18 0.121
reactive oxygen species biosynthetic process GO:1903409 8 0.121
regulation of chemokine production GO:0032642 30 0.120
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.120
regulation of neutrophil chemotaxis GO:0090022 14 0.120
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.119
organic acid transport GO:0015849 101 0.119
Mouse
pattern recognition receptor signaling pathway GO:0002221 47 0.118
positive regulation of apoptotic process GO:0043065 217 0.118
regulation of protein catabolic process GO:0042176 108 0.118
thymocyte migration GO:0072679 2 0.116
ribonucleotide catabolic process GO:0009261 208 0.116
adaptive immune response GO:0002250 155 0.116
aromatic compound catabolic process GO:0019439 286 0.116
regulation of cell adhesion GO:0030155 154 0.115
protein localization to nucleus GO:0034504 121 0.114
sequestering of calcium ion GO:0051208 18 0.114
cell adhesion GO:0007155 329 0.113
regulation of neutrophil migration GO:1902622 14 0.112
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.112
regulation of angiogenesis GO:0045765 81 0.112
fat soluble vitamin metabolic process GO:0006775 11 0.111
stress activated mapk cascade GO:0051403 80 0.111
Mouse
regulation of glucose transport GO:0010827 32 0.110
Mouse
positive regulation of protein secretion GO:0050714 52 0.110
Human
angiogenesis GO:0001525 201 0.110
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.110
regulation of lymphocyte apoptotic process GO:0070228 41 0.108
interleukin 8 production GO:0032637 4 0.108
organonitrogen compound catabolic process GO:1901565 264 0.108
lipid catabolic process GO:0016042 69 0.108
Mouse
activation of mapk activity GO:0000187 59 0.108
protein processing GO:0016485 163 0.106
protein import GO:0017038 101 0.106
endocrine process GO:0050886 39 0.105
Mouse
glycosyl compound catabolic process GO:1901658 206 0.105
interferon gamma production GO:0032609 67 0.105
positive regulation of interleukin 8 production GO:0032757 2 0.105
membrane organization GO:0061024 245 0.105
positive regulation of cellular amine metabolic process GO:0033240 5 0.104
positive regulation of chemotaxis GO:0050921 38 0.102
regulation of establishment of protein localization GO:0070201 181 0.102
Human
regulation of fatty acid transport GO:2000191 10 0.101
Mouse
nitric oxide biosynthetic process GO:0006809 25 0.101
regulation of protein secretion GO:0050708 82 0.101
Human
positive regulation of homeostatic process GO:0032846 64 0.101
Mouse
mucopolysaccharide metabolic process GO:1903510 25 0.101
regulation of kinase activity GO:0043549 249 0.100
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.100
positive regulation of eosinophil migration GO:2000418 2 0.100
protein secretion GO:0009306 111 0.099
Human
regulation of ion homeostasis GO:2000021 64 0.099
positive regulation of cell death GO:0010942 224 0.098
regulation of thymocyte migration GO:2000410 2 0.097
macrophage chemotaxis GO:0048246 14 0.097
tissue remodeling GO:0048771 102 0.096
negative regulation of hydrolase activity GO:0051346 71 0.096
lipid localization GO:0010876 126 0.095
Mouse
immune effector process GO:0002252 321 0.094
skeletal muscle fiber development GO:0048741 58 0.094
positive regulation of steroid biosynthetic process GO:0010893 4 0.094
positive regulation of intracellular transport GO:0032388 70 0.093
positive regulation of thymocyte migration GO:2000412 2 0.092
positive regulation of cell development GO:0010720 237 0.092
cellular metal ion homeostasis GO:0006875 151 0.092
immune response regulating signaling pathway GO:0002764 125 0.092
regulation of cellular amine metabolic process GO:0033238 20 0.092
interleukin 1 beta production GO:0032611 30 0.092
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.091
Mouse
positive regulation of hematopoietic stem cell proliferation GO:1902035 2 0.090
t helper 2 cell cytokine production GO:0035745 4 0.090
regulation of eosinophil migration GO:2000416 2 0.089
cytoplasmic transport GO:0016482 234 0.089
negative regulation of phosphorylation GO:0042326 166 0.089
Mouse
negative regulation of immune system process GO:0002683 209 0.088
regulation of hormone secretion GO:0046883 88 0.088
Mouse
regulation of intracellular transport GO:0032386 159 0.088
peptide hormone secretion GO:0030072 109 0.088
Mouse
response to insulin GO:0032868 100 0.087
Mouse
interleukin 12 secretion GO:0072610 3 0.087
blood vessel morphogenesis GO:0048514 285 0.087
positive regulation of ion transport GO:0043270 65 0.087
Mouse
organic hydroxy compound biosynthetic process GO:1901617 77 0.087
cellular response to insulin stimulus GO:0032869 78 0.086
Mouse
positive regulation of protein transport GO:0051222 93 0.086
Human
regulation of prostaglandin secretion GO:0032306 5 0.086
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.086
homotypic cell cell adhesion GO:0034109 28 0.085
multicellular organismal homeostasis GO:0048871 164 0.085
Mouse
icosanoid transport GO:0071715 14 0.084
Mouse
regulation of steroid metabolic process GO:0019218 39 0.084
detection of yeast GO:0001879 2 0.084
cytosolic calcium ion transport GO:0060401 48 0.083
b cell chemotaxis GO:0035754 3 0.083
response to growth factor GO:0070848 198 0.083
monosaccharide transport GO:0015749 58 0.082
Mouse
lymphocyte activation involved in immune response GO:0002285 93 0.081
negative regulation of apoptotic signaling pathway GO:2001234 104 0.081
response to alcohol GO:0097305 48 0.081
regulation of t cell differentiation GO:0045580 83 0.081
cellular response to drug GO:0035690 15 0.078
positive regulation of intracellular protein transport GO:0090316 42 0.078
cell type specific apoptotic process GO:0097285 268 0.078
purine nucleoside triphosphate metabolic process GO:0009144 226 0.078
positive regulation vascular endothelial growth factor production GO:0010575 10 0.077
cellular response to peptide GO:1901653 92 0.077
Mouse
negative regulation of kinase activity GO:0033673 81 0.077
Mouse
peptidyl amino acid modification GO:0018193 336 0.077
calcium ion homeostasis GO:0055074 127 0.076
regulation of organic acid transport GO:0032890 16 0.076
Mouse
regulation of protein kinase activity GO:0045859 232 0.076
Mouse
regulation of interleukin 6 production GO:0032675 55 0.076
Mouse
regulation of interleukin 2 biosynthetic process GO:0045076 13 0.075
Human
regulation of defense response to bacterium GO:1900424 3 0.075
peptide secretion GO:0002790 114 0.075
Mouse
prostaglandin transport GO:0015732 7 0.075
Mouse
peptidyl tyrosine modification GO:0018212 145 0.074
t cell apoptotic process GO:0070231 39 0.074
small gtpase mediated signal transduction GO:0007264 97 0.074
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.074
negative regulation of secretion by cell GO:1903531 54 0.073
Mouse
response to peptide GO:1901652 136 0.073
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.072
purine containing compound catabolic process GO:0072523 213 0.071
nitric oxide metabolic process GO:0046209 25 0.071
regulation of nik nf kappab signaling GO:1901222 10 0.071
Zebrafish
insulin receptor signaling pathway GO:0008286 49 0.071
Mouse
monocarboxylic acid transport GO:0015718 44 0.071
Mouse
sequestering of metal ion GO:0051238 19 0.071
phosphatidylinositol mediated signaling GO:0048015 41 0.071
organic cyclic compound catabolic process GO:1901361 295 0.070
heat generation GO:0031649 13 0.070
Mouse
cellular response to external stimulus GO:0071496 88 0.070
lymphocyte apoptotic process GO:0070227 54 0.070
carbohydrate transport GO:0008643 62 0.069
Mouse
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.069
exocytosis GO:0006887 121 0.069
regulation of membrane potential GO:0042391 192 0.069
antibacterial peptide biosynthetic process GO:0002780 2 0.068
regulation of monocyte chemotactic protein 1 production GO:0071637 1 0.068
regulation of nitric oxide biosynthetic process GO:0045428 18 0.068
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.068
regulation of protein kinase b signaling GO:0051896 56 0.068
negative regulation of proteolysis GO:0045861 74 0.068
nucleoside phosphate metabolic process GO:0006753 338 0.067
regulation of protein localization GO:0032880 231 0.067
Human
purine nucleoside triphosphate catabolic process GO:0009146 203 0.067
cellular ion homeostasis GO:0006873 165 0.067
nuclear transport GO:0051169 139 0.066
protein localization to organelle GO:0033365 185 0.066
muscle cell differentiation GO:0042692 261 0.066
regulation of protein transport GO:0051223 163 0.066
Human
epithelial cell proliferation GO:0050673 174 0.066
immune response activating signal transduction GO:0002757 116 0.066
regulation of secretion by cell GO:1903530 249 0.066
Human Mouse
negative regulation of cell activation GO:0050866 111 0.065
myotube differentiation GO:0014902 105 0.065
negative regulation of cell proliferation GO:0008285 296 0.065
Human
response to drug GO:0042493 75 0.065
regulation of system process GO:0044057 200 0.065
Mouse
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.064
Mouse
nuclear division GO:0000280 158 0.064
Human
mononuclear cell migration GO:0071674 8 0.064
ribonucleoside catabolic process GO:0042454 206 0.064
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.063
fat cell differentiation GO:0045444 160 0.063
positive regulation of hydrolase activity GO:0051345 148 0.063
intracellular protein transport GO:0006886 204 0.063
positive regulation of jnk cascade GO:0046330 46 0.063
Mouse
endocytosis GO:0006897 168 0.063
protein import into nucleus GO:0006606 95 0.063
fatty acid transport GO:0015908 28 0.063
Mouse
lipid transport GO:0006869 98 0.062
Mouse
negative regulation of hormone secretion GO:0046888 20 0.062
Mouse
lymphocyte differentiation GO:0030098 242 0.062
morphogenesis of a branching structure GO:0001763 203 0.062
regulation of ras protein signal transduction GO:0046578 114 0.061
negative regulation of transferase activity GO:0051348 85 0.061
Mouse
positive regulation of behavior GO:0048520 40 0.060
positive regulation of prostaglandin secretion GO:0032308 5 0.060
Mouse
negative regulation of toll like receptor 2 signaling pathway GO:0034136 3 0.060
heterocycle catabolic process GO:0046700 280 0.060
regulation of lipid biosynthetic process GO:0046890 54 0.060
ribonucleoside metabolic process GO:0009119 245 0.060
positive regulation of stress activated mapk cascade GO:0032874 48 0.060
Mouse
single organism nuclear import GO:1902593 95 0.059
positive regulation of cytokine secretion GO:0050715 41 0.059
Human
cellular response to oxidative stress GO:0034599 76 0.059
regulation of rho protein signal transduction GO:0035023 71 0.059
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.059
regulation of nuclear division GO:0051783 56 0.058
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.058
gtp catabolic process GO:0006184 143 0.058
purine nucleoside metabolic process GO:0042278 241 0.058
regulation of cell cycle process GO:0010564 160 0.058
Human
positive regulation of mapk cascade GO:0043410 170 0.058
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.058
nucleoside phosphate catabolic process GO:1901292 222 0.057
alpha beta t cell activation GO:0046631 91 0.057
ribonucleoside triphosphate metabolic process GO:0009199 220 0.057
regulation of protein localization to nucleus GO:1900180 60 0.057
acid secretion GO:0046717 33 0.057
Mouse
negative regulation of endopeptidase activity GO:0010951 44 0.057
negative regulation of cytokine production GO:0001818 84 0.057
Mouse
regulation of protein maturation GO:1903317 96 0.056
negative regulation of intracellular signal transduction GO:1902532 167 0.056
Mouse
myoblast differentiation GO:0045445 52 0.056
regulation of vitamin metabolic process GO:0030656 3 0.056
nucleoside metabolic process GO:0009116 246 0.056
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.055
Mouse
connective tissue replacement involved in inflammatory response wound healing GO:0002248 3 0.055
glucose transport GO:0015758 56 0.055
Mouse
gtp metabolic process GO:0046039 144 0.055
nucleoside triphosphate catabolic process GO:0009143 205 0.055
sequestering of triglyceride GO:0030730 6 0.054
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.054
divalent metal ion transport GO:0070838 172 0.054
regulation of neutrophil mediated killing of bacterium GO:0070950 1 0.054
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.054
mammary gland epithelium development GO:0061180 65 0.054
cellular response to organonitrogen compound GO:0071417 145 0.054
Mouse
inositol lipid mediated signaling GO:0048017 41 0.053
hexose transport GO:0008645 56 0.053
Mouse
eosinophil migration GO:0072677 3 0.053
cellular response to molecule of fungal origin GO:0071226 2 0.053
regulation of cytoplasmic transport GO:1903649 112 0.053
positive regulation of nucleoside metabolic process GO:0045979 91 0.052
i kappab kinase nf kappab signaling GO:0007249 85 0.052
Mouse
regulation of granulocyte chemotaxis GO:0071622 17 0.052
regulation of organelle organization GO:0033043 289 0.052
Human
nuclear import GO:0051170 95 0.052
muscle fiber development GO:0048747 76 0.052
negative regulation of molecular function GO:0044092 258 0.052
Mouse
regulation of multi organism process GO:0043900 111 0.052
regulation of lipid transport GO:0032368 36 0.052
Mouse
myotube cell development GO:0014904 60 0.051
interleukin 1 secretion GO:0050701 16 0.051
regulation of icosanoid secretion GO:0032303 8 0.051
Mouse
ectopic germ cell programmed cell death GO:0035234 9 0.051
cell substrate adhesion GO:0031589 130 0.051
aminoglycan metabolic process GO:0006022 34 0.051
positive regulation of interleukin 6 biosynthetic process GO:0045410 6 0.051
Mouse
purine nucleoside catabolic process GO:0006152 205 0.051
positive regulation of neutrophil migration GO:1902624 12 0.051
positive regulation of protein localization to nucleus GO:1900182 30 0.050
regulation of intracellular protein transport GO:0033157 82 0.050
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.050
second messenger mediated signaling GO:0019932 73 0.050
regulation of interleukin 1 beta secretion GO:0050706 15 0.050
morphogenesis of a branching epithelium GO:0061138 193 0.050
regulation of cellular response to insulin stimulus GO:1900076 30 0.049
Mouse
regulation of ion transport GO:0043269 215 0.049
Mouse
regulation of b cell chemotaxis GO:2000537 2 0.049
extracellular structure organization GO:0043062 148 0.049
glycoprotein metabolic process GO:0009100 116 0.049
purine ribonucleoside catabolic process GO:0046130 205 0.049
inflammatory cell apoptotic process GO:0006925 11 0.049
leukocyte mediated immunity GO:0002443 174 0.049
response to oxidative stress GO:0006979 123 0.048
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.048
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.048
purine nucleotide metabolic process GO:0006163 302 0.048
regulation of peptidase activity GO:0052547 96 0.048
positive regulation of response to wounding GO:1903036 66 0.048
Mouse
astrocyte cell migration GO:0043615 3 0.048
cytokine mediated signaling pathway GO:0019221 115 0.048
Human
negative regulation of mapk cascade GO:0043409 65 0.048
Mouse
hyaluronan metabolic process GO:0030212 4 0.048
positive regulation of inflammatory response GO:0050729 47 0.048
Mouse
peptide transport GO:0015833 133 0.048
Mouse
regulation of monooxygenase activity GO:0032768 7 0.047
cell killing GO:0001906 67 0.047
organophosphate catabolic process GO:0046434 232 0.047
defense response to virus GO:0051607 68 0.047
nucleoside catabolic process GO:0009164 206 0.047
positive regulation of b cell chemotaxis GO:2000538 2 0.047
response to transforming growth factor beta GO:0071559 88 0.047
positive regulation of secretion GO:0051047 130 0.047
Human Mouse
positive regulation of organic acid transport GO:0032892 11 0.047
Mouse
regulation of cell projection assembly GO:0060491 38 0.047
icosanoid secretion GO:0032309 12 0.047
Mouse
striated muscle cell development GO:0055002 125 0.047
positive regulation of lymphocyte migration GO:2000403 11 0.046
coagulation GO:0050817 78 0.046
purine nucleotide catabolic process GO:0006195 211 0.046
response to inorganic substance GO:0010035 96 0.046
Human

Il1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.130
cancer DOID:162 0 0.097
organ system cancer DOID:0050686 0 0.097
gastrointestinal system cancer DOID:3119 0 0.079