Mus musculus

0 known processes

Def8

differentially expressed in FDCP 8

(Aliases: D8Ertd713e,AI449518)

Def8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.113
organonitrogen compound catabolic process GO:1901565 264 0.063
cation transmembrane transport GO:0098655 266 0.060
oxidation reduction process GO:0055114 342 0.054
anion transport GO:0006820 177 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.053
organic acid transport GO:0015849 101 0.053
nucleoside phosphate metabolic process GO:0006753 338 0.051
carbohydrate derivative biosynthetic process GO:1901137 183 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.047
ribonucleoside metabolic process GO:0009119 245 0.046
cellular ketone metabolic process GO:0042180 84 0.046
nucleoside metabolic process GO:0009116 246 0.043
cation transport GO:0006812 399 0.043
ion transmembrane transport GO:0034220 361 0.042
organic anion transport GO:0015711 137 0.041
purine nucleoside triphosphate metabolic process GO:0009144 226 0.041
purine nucleoside metabolic process GO:0042278 241 0.039
purine nucleotide metabolic process GO:0006163 302 0.039
glycosyl compound metabolic process GO:1901657 246 0.038
intracellular protein transport GO:0006886 204 0.038
purine ribonucleoside catabolic process GO:0046130 205 0.038
aromatic compound catabolic process GO:0019439 286 0.037
purine containing compound metabolic process GO:0072521 311 0.035
peptidyl amino acid modification GO:0018193 336 0.035
cellular amine metabolic process GO:0044106 44 0.034
ras protein signal transduction GO:0007265 77 0.034
cofactor metabolic process GO:0051186 80 0.034
transmembrane transport GO:0055085 412 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
organonitrogen compound biosynthetic process GO:1901566 192 0.034
apoptotic signaling pathway GO:0097190 306 0.033
cellular lipid metabolic process GO:0044255 323 0.033
amine metabolic process GO:0009308 45 0.033
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
sulfur compound metabolic process GO:0006790 100 0.033
purine ribonucleoside metabolic process GO:0046128 241 0.032
cytoplasmic transport GO:0016482 234 0.032
inorganic ion transmembrane transport GO:0098660 234 0.031
sodium ion transmembrane transport GO:0035725 49 0.031
heterocycle catabolic process GO:0046700 280 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.030
purine nucleoside catabolic process GO:0006152 205 0.030
nucleotide metabolic process GO:0009117 332 0.030
regulation of secretion GO:0051046 274 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
alpha amino acid metabolic process GO:1901605 59 0.029
carboxylic acid catabolic process GO:0046395 51 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
regulation of cellular component biogenesis GO:0044087 181 0.029
regulation of cellular catabolic process GO:0031329 242 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.029
compound eye development GO:0048749 1 0.029
small gtpase mediated signal transduction GO:0007264 97 0.028
regulation of cell activation GO:0050865 289 0.028
male sex differentiation GO:0046661 109 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.026
positive regulation of programmed cell death GO:0043068 218 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
ribonucleoside catabolic process GO:0042454 206 0.026
inflammatory response GO:0006954 244 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
regulation of hormone levels GO:0010817 211 0.025
regulation of homeostatic process GO:0032844 182 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
negative regulation of molecular function GO:0044092 258 0.025
protein processing GO:0016485 163 0.024
nucleotide catabolic process GO:0009166 217 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
inorganic cation transmembrane transport GO:0098662 207 0.024
regulation of defense response GO:0031347 233 0.024
protein maturation GO:0051604 176 0.024
adiponectin activated signaling pathway GO:0033211 4 0.023
protein targeting GO:0006605 143 0.023
positive regulation of cell death GO:0010942 224 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
cellular homeostasis GO:0019725 240 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
development of primary male sexual characteristics GO:0046546 88 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
cellular chemical homeostasis GO:0055082 215 0.023
cation homeostasis GO:0055080 212 0.022
response to organonitrogen compound GO:0010243 246 0.022
organophosphate catabolic process GO:0046434 232 0.022
regulation of ion transmembrane transporter activity GO:0032412 54 0.022
endocytosis GO:0006897 168 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
lytic vacuole organization GO:0080171 21 0.022
organic cyclic compound catabolic process GO:1901361 295 0.021
regulation of hydrolase activity GO:0051336 246 0.021
glycoprotein biosynthetic process GO:0009101 89 0.021
regulation of neuron death GO:1901214 134 0.021
gland development GO:0048732 330 0.021
lipid transport GO:0006869 98 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
endomembrane system organization GO:0010256 147 0.021
forebrain development GO:0030900 302 0.021
monocarboxylic acid metabolic process GO:0032787 191 0.021
morphogenesis of a branching structure GO:0001763 203 0.021
cellular amino acid catabolic process GO:0009063 25 0.020
nuclear transport GO:0051169 139 0.020
oocyte axis specification GO:0007309 2 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
metal ion homeostasis GO:0055065 189 0.020
glucose homeostasis GO:0042593 128 0.020
actin cytoskeleton organization GO:0030036 220 0.020
leukocyte differentiation GO:0002521 342 0.020
glycoprotein metabolic process GO:0009100 116 0.020
vacuole organization GO:0007033 38 0.020
regulation of cell motility GO:2000145 236 0.020
macromolecule catabolic process GO:0009057 281 0.020
positive regulation of secretion GO:0051047 130 0.020
regulation of cell migration GO:0030334 219 0.019
regulation of protein localization GO:0032880 231 0.019
very long chain fatty acid catabolic process GO:0042760 2 0.019
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.019
neurotransmitter transport GO:0006836 76 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
synaptic transmission GO:0007268 329 0.019
purine containing compound catabolic process GO:0072523 213 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
regulation of cellular response to stress GO:0080135 159 0.018
fatty acid transmembrane transport GO:1902001 1 0.018
negative regulation of neuron apoptotic process GO:0043524 92 0.018
t cell activation GO:0042110 289 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
developmental maturation GO:0021700 193 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
positive regulation of protein modification process GO:0031401 299 0.018
telencephalon development GO:0021537 186 0.018
cellular modified amino acid metabolic process GO:0006575 63 0.018
regulation of kinase activity GO:0043549 249 0.017
small molecule catabolic process GO:0044282 71 0.017
response to inorganic substance GO:0010035 96 0.017
nitrogen compound transport GO:0071705 271 0.017
carbohydrate metabolic process GO:0005975 230 0.017
carbohydrate homeostasis GO:0033500 128 0.017
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.017
cellular amino acid biosynthetic process GO:0008652 22 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
carboxylic acid transport GO:0046942 100 0.017
stem cell development GO:0048864 219 0.017
vesicle localization GO:0051648 86 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
oocyte construction GO:0007308 2 0.016
cellular ion homeostasis GO:0006873 165 0.016
protein catabolic process GO:0030163 221 0.016
rho protein signal transduction GO:0007266 32 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
glycerolipid metabolic process GO:0046486 122 0.016
skin development GO:0043588 220 0.016
sensory perception GO:0007600 245 0.016
lipid localization GO:0010876 126 0.016
alpha amino acid catabolic process GO:1901606 18 0.016
tube formation GO:0035148 140 0.016
gtp metabolic process GO:0046039 144 0.016
skeletal system development GO:0001501 356 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
neuron death GO:0070997 154 0.016
neuron apoptotic process GO:0051402 142 0.016
response to organic cyclic compound GO:0014070 198 0.016
response to oxidative stress GO:0006979 123 0.016
regulation of protein kinase activity GO:0045859 232 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
neural tube development GO:0021915 160 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
regulation of secretion by cell GO:1903530 249 0.015
regulation of proteolysis GO:0030162 164 0.015
organelle localization GO:0051640 179 0.015
regulation of ossification GO:0030278 112 0.015
ossification GO:0001503 216 0.015
retrograde transport endosome to golgi GO:0042147 2 0.015
cellular response to lipid GO:0071396 145 0.015
regulation of feeding behavior GO:0060259 3 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
regulation of transferase activity GO:0051338 263 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
signal transduction in absence of ligand GO:0038034 55 0.015
sodium ion transport GO:0006814 73 0.015
alpha amino acid biosynthetic process GO:1901607 15 0.015
divalent inorganic cation transport GO:0072511 178 0.015
negative regulation of cell cycle GO:0045786 123 0.014
negative regulation of nervous system development GO:0051961 156 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
membrane organization GO:0061024 245 0.014
regulation of membrane potential GO:0042391 192 0.014
cell type specific apoptotic process GO:0097285 268 0.014
cytokine production GO:0001816 319 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
protein glycosylation GO:0006486 55 0.014
wnt signaling pathway GO:0016055 188 0.014
appendage development GO:0048736 166 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
stem cell differentiation GO:0048863 268 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
protein localization to organelle GO:0033365 185 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
microtubule based process GO:0007017 236 0.014
regulation of cell adhesion GO:0030155 154 0.014
cell substrate adhesion GO:0031589 130 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
regulation of metal ion transport GO:0010959 106 0.014
cellular metal ion homeostasis GO:0006875 151 0.013
leukocyte proliferation GO:0070661 172 0.013
lysosome organization GO:0007040 21 0.013
regulation of organelle organization GO:0033043 289 0.013
gtp catabolic process GO:0006184 143 0.013
sequestering of calcium ion GO:0051208 18 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
epithelial tube formation GO:0072175 130 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
response to radiation GO:0009314 165 0.013
autophagy GO:0006914 45 0.013
sensory system development GO:0048880 3 0.013
establishment of vesicle localization GO:0051650 81 0.013
positive regulation of kinase activity GO:0033674 155 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
organic hydroxy compound transport GO:0015850 93 0.013
learning GO:0007612 98 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
pallium development GO:0021543 120 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
regionalization GO:0003002 337 0.013
amide transport GO:0042886 138 0.012
lymphocyte proliferation GO:0046651 164 0.012
nucleoside catabolic process GO:0009164 206 0.012
plasma membrane organization GO:0007009 90 0.012
glycosylation GO:0070085 62 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
dephosphorylation GO:0016311 129 0.012
regulation of cytokine production GO:0001817 266 0.012
negative regulation of protein modification process GO:0031400 163 0.012
lateral inhibition GO:0046331 1 0.012
tube closure GO:0060606 91 0.012
maintenance of location GO:0051235 89 0.012
organic acid biosynthetic process GO:0016053 86 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
regulation of protein maturation GO:1903317 96 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
negative regulation of cell development GO:0010721 169 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
calcium ion homeostasis GO:0055074 127 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
appendage morphogenesis GO:0035107 149 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
limb development GO:0060173 166 0.012
urogenital system development GO:0001655 261 0.012
response to peptide GO:1901652 136 0.012
anatomical structure homeostasis GO:0060249 145 0.011
blood vessel morphogenesis GO:0048514 285 0.011
cell adhesion GO:0007155 329 0.011
monocarboxylic acid transport GO:0015718 44 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
amino acid transport GO:0006865 61 0.011
protein localization to nucleus GO:0034504 121 0.011
protein ubiquitination GO:0016567 171 0.011
lymphocyte differentiation GO:0030098 242 0.011
rap protein signal transduction GO:0032486 3 0.011
regulation of translation GO:0006417 71 0.011
translation GO:0006412 93 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
cell fate commitment GO:0045165 210 0.011
locomotory behavior GO:0007626 195 0.011
coenzyme metabolic process GO:0006732 52 0.011
peptide transport GO:0015833 133 0.011
respiratory tube development GO:0030323 167 0.011
cofactor biosynthetic process GO:0051188 41 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
glycerophospholipid metabolic process GO:0006650 71 0.011
cellular response to nutrient levels GO:0031669 64 0.011
immune effector process GO:0002252 321 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
regulation of transmembrane transport GO:0034762 128 0.011
circulatory system process GO:0003013 197 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
lateral line system development GO:0048925 1 0.011
fatty acid metabolic process GO:0006631 121 0.011
fatty acid transport GO:0015908 28 0.011
spermatogenesis GO:0007283 284 0.011
asymmetric stem cell division GO:0098722 3 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
lipid biosynthetic process GO:0008610 179 0.011
regulation of ion transport GO:0043269 215 0.011
adult behavior GO:0030534 135 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
regulation of cell cycle GO:0051726 281 0.011
macromolecule glycosylation GO:0043413 55 0.011
actin filament organization GO:0007015 113 0.010
protein import into nucleus GO:0006606 95 0.010
aspartate family amino acid metabolic process GO:0009066 10 0.010
cellular response to oxidative stress GO:0034599 76 0.010
regulation of cell cycle process GO:0010564 160 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
regulation of synaptic plasticity GO:0048167 87 0.010
tissue homeostasis GO:0001894 115 0.010
divalent metal ion transport GO:0070838 172 0.010
regulation of endocytosis GO:0030100 69 0.010
development of primary sexual characteristics GO:0045137 143 0.010
chemotaxis GO:0006935 247 0.010
regulation of cell size GO:0008361 72 0.010
spermatid differentiation GO:0048515 115 0.010
regulation of peptide transport GO:0090087 91 0.010
negative regulation of synapse assembly GO:0051964 3 0.010
atp metabolic process GO:0046034 75 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010

Def8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
cancer DOID:162 0 0.020
organ system cancer DOID:0050686 0 0.020
disease of anatomical entity DOID:7 0 0.019
immune system disease DOID:2914 0 0.019
inherited metabolic disorder DOID:655 0 0.016
nervous system disease DOID:863 0 0.014
hematopoietic system disease DOID:74 0 0.012
central nervous system disease DOID:331 0 0.011