Mus musculus

41 known processes

Degs1

degenerative spermatocyte homolog 1 (Drosophila)

(Aliases: Mdes,Degs,Des1,AA536663)

Degs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation homeostasis GO:0055080 212 0.152
ion transmembrane transport GO:0034220 361 0.146
transmembrane transport GO:0055085 412 0.102
cation transport GO:0006812 399 0.101
anion transport GO:0006820 177 0.100
organic anion transport GO:0015711 137 0.095
inorganic ion transmembrane transport GO:0098660 234 0.086
metal ion homeostasis GO:0055065 189 0.079
cation transmembrane transport GO:0098655 266 0.078
cytokine production GO:0001816 319 0.076
engulfment of apoptotic cell GO:0043652 3 0.075
membrane lipid biosynthetic process GO:0046467 32 0.074
membrane organization GO:0061024 245 0.070
mapk cascade GO:0000165 281 0.068
immune effector process GO:0002252 321 0.061
regulation of cytokine production GO:0001817 266 0.061
organic acid transport GO:0015849 101 0.060
cellular lipid metabolic process GO:0044255 323 0.059
sphingolipid biosynthetic process GO:0030148 26 0.054
endomembrane system organization GO:0010256 147 0.053
divalent metal ion transport GO:0070838 172 0.051
regulation of homeostatic process GO:0032844 182 0.051
regulation of cell motility GO:2000145 236 0.049
cellular ion homeostasis GO:0006873 165 0.048
calcium ion homeostasis GO:0055074 127 0.048
lipid transport GO:0006869 98 0.044
regulation of secretion GO:0051046 274 0.043
regulation of angiotensin metabolic process GO:0060177 4 0.041
positive regulation of neutrophil apoptotic process GO:0033031 1 0.041
cellular amino acid metabolic process GO:0006520 103 0.041
angiogenesis GO:0001525 201 0.040
cellular chemical homeostasis GO:0055082 215 0.040
cell adhesion GO:0007155 329 0.040
amine metabolic process GO:0009308 45 0.039
carboxylic acid transport GO:0046942 100 0.039
positive regulation of programmed cell death GO:0043068 218 0.037
positive regulation of apoptotic process GO:0043065 217 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
regulation of protein localization GO:0032880 231 0.035
cellular homeostasis GO:0019725 240 0.035
leukocyte differentiation GO:0002521 342 0.035
cellular amine metabolic process GO:0044106 44 0.035
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.034
regulation of organelle organization GO:0033043 289 0.034
inorganic cation transmembrane transport GO:0098662 207 0.034
nucleoside metabolic process GO:0009116 246 0.034
t cell activation GO:0042110 289 0.033
interleukin 8 secretion GO:0072606 3 0.033
cellular metal ion homeostasis GO:0006875 151 0.033
blood vessel morphogenesis GO:0048514 285 0.032
protein processing GO:0016485 163 0.031
hemostasis GO:0007599 78 0.031
lymphocyte differentiation GO:0030098 242 0.031
regulation of mapk cascade GO:0043408 248 0.031
organic hydroxy compound metabolic process GO:1901615 203 0.030
regulation of vesicle mediated transport GO:0060627 139 0.030
ceramide biosynthetic process GO:0046513 20 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.029
blood coagulation GO:0007596 76 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
leukocyte mediated immunity GO:0002443 174 0.028
regulation of membrane potential GO:0042391 192 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
regulation of hydrolase activity GO:0051336 246 0.027
tissue remodeling GO:0048771 102 0.027
positive regulation of homeostatic process GO:0032846 64 0.027
response to acid chemical GO:0001101 111 0.027
calcium ion transport GO:0006816 159 0.027
negative regulation of interleukin 8 secretion GO:2000483 1 0.026
apoptotic signaling pathway GO:0097190 306 0.026
regionalization GO:0003002 337 0.026
homeostasis of number of cells GO:0048872 210 0.026
cellular divalent inorganic cation homeostasis GO:0072503 127 0.026
negative regulation of molecular function GO:0044092 258 0.026
regulation of wnt signaling pathway GO:0030111 123 0.026
protein localization to membrane GO:0072657 108 0.026
muscle contraction GO:0006936 101 0.026
divalent inorganic cation homeostasis GO:0072507 138 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
organelle assembly GO:0070925 177 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
protein catabolic process GO:0030163 221 0.024
regulation of neutrophil apoptotic process GO:0033029 1 0.024
oxidation reduction process GO:0055114 342 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.024
nucleotide metabolic process GO:0009117 332 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
divalent inorganic cation transport GO:0072511 178 0.024
actin polymerization or depolymerization GO:0008154 54 0.023
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.023
leukocyte homeostasis GO:0001776 79 0.023
lymphocyte mediated immunity GO:0002449 139 0.023
intracellular protein transport GO:0006886 204 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.023
cell cell junction organization GO:0045216 72 0.022
fibrinolysis GO:0042730 3 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
mitotic cell cycle process GO:1903047 159 0.022
multi multicellular organism process GO:0044706 109 0.022
positive regulation of cell death GO:0010942 224 0.022
organophosphate catabolic process GO:0046434 232 0.021
peptidyl amino acid modification GO:0018193 336 0.021
heterocycle catabolic process GO:0046700 280 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
ameboidal type cell migration GO:0001667 128 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
regulation of cellular amino acid metabolic process GO:0006521 5 0.021
regulation of cell migration GO:0030334 219 0.021
sphingolipid metabolic process GO:0006665 45 0.021
positive regulation of protein modification process GO:0031401 299 0.021
regulation of cell activation GO:0050865 289 0.021
regulation of anatomical structure size GO:0090066 178 0.021
cellular ketone metabolic process GO:0042180 84 0.021
muscle system process GO:0003012 141 0.021
ossification GO:0001503 216 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
acid secretion GO:0046717 33 0.020
regulation of protein transport GO:0051223 163 0.020
wnt signaling pathway GO:0016055 188 0.020
regulation of secretion by cell GO:1903530 249 0.020
mitotic cell cycle GO:0000278 195 0.020
b cell activation GO:0042113 161 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.020
amide transport GO:0042886 138 0.020
mitotic cytokinesis GO:0000281 4 0.019
negative regulation of cytokine production GO:0001818 84 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
nucleotide catabolic process GO:0009166 217 0.019
regulation of interleukin 8 production GO:0032677 3 0.019
regulation of response to wounding GO:1903034 189 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
skin development GO:0043588 220 0.019
adaptive immune response GO:0002250 155 0.019
phagocytosis GO:0006909 66 0.019
transmission of nerve impulse GO:0019226 76 0.019
cellular calcium ion homeostasis GO:0006874 119 0.019
regulation of ossification GO:0030278 112 0.019
neutrophil apoptotic process GO:0001781 3 0.019
mitochondrion degradation GO:0000422 3 0.018
gland development GO:0048732 330 0.018
t cell differentiation GO:0030217 174 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
transition metal ion transport GO:0000041 38 0.018
nitrogen compound transport GO:0071705 271 0.018
regulation of muscle contraction GO:0006937 49 0.018
positive regulation of cell adhesion GO:0045785 80 0.017
endocytosis GO:0006897 168 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
inflammatory response GO:0006954 244 0.017
regulation of exocytosis GO:0017157 61 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
cell substrate adhesion GO:0031589 130 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
positive regulation of cell motility GO:2000147 116 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
regulation of interleukin 8 secretion GO:2000482 2 0.017
regulation of angiotensin levels in blood GO:0002002 4 0.017
actin filament organization GO:0007015 113 0.017
monocarboxylic acid transport GO:0015718 44 0.017
aromatic compound catabolic process GO:0019439 286 0.017
regulation of peptidase activity GO:0052547 96 0.017
regulation of cell adhesion GO:0030155 154 0.017
nucleoside catabolic process GO:0009164 206 0.017
skeletal system development GO:0001501 356 0.017
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
neural tube development GO:0021915 160 0.016
regulation of hormone levels GO:0010817 211 0.016
cellular response to lipid GO:0071396 145 0.016
cellular protein catabolic process GO:0044257 155 0.016
phospholipid metabolic process GO:0006644 87 0.016
carbohydrate metabolic process GO:0005975 230 0.016
exocytosis GO:0006887 121 0.016
macromolecule catabolic process GO:0009057 281 0.016
protein localization to plasma membrane GO:0072659 57 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
hormone metabolic process GO:0042445 86 0.016
positive regulation of wnt signaling pathway GO:0030177 45 0.016
alpha beta t cell differentiation GO:0046632 69 0.016
regulation of hemostasis GO:1900046 28 0.016
plasma membrane organization GO:0007009 90 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
regulation of muscle system process GO:0090257 80 0.016
regulation of neuron projection development GO:0010975 169 0.016
ribose phosphate metabolic process GO:0019693 291 0.015
ceramide metabolic process GO:0006672 31 0.015
regulation of system process GO:0044057 200 0.015
positive regulation of cytokine production GO:0001819 174 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
leukocyte apoptotic process GO:0071887 71 0.015
regulation of synaptic plasticity GO:0048167 87 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
circulatory system process GO:0003013 197 0.015
cell activation involved in immune response GO:0002263 126 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
myeloid cell apoptotic process GO:0033028 22 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.014
regulation of cell cycle GO:0051726 281 0.014
myeloid cell differentiation GO:0030099 233 0.014
regulation of cell substrate adhesion GO:0010810 73 0.014
response to organonitrogen compound GO:0010243 246 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
regulation of transferase activity GO:0051338 263 0.014
small molecule biosynthetic process GO:0044283 132 0.014
glycerolipid metabolic process GO:0046486 122 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
organelle localization GO:0051640 179 0.014
fatty acid derivative transport GO:1901571 14 0.014
germ cell development GO:0007281 185 0.014
epidermis development GO:0008544 187 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
defense response to bacterium GO:0042742 119 0.014
tissue homeostasis GO:0001894 115 0.014
regulation of t cell activation GO:0050863 170 0.014
regulation of body fluid levels GO:0050878 162 0.014
interleukin 8 production GO:0032637 4 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
regulation of protein catabolic process GO:0042176 108 0.014
heart morphogenesis GO:0003007 178 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
transition metal ion homeostasis GO:0055076 54 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
protein localization to organelle GO:0033365 185 0.013
sequestering of metal ion GO:0051238 19 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
positive regulation of cell development GO:0010720 237 0.013
lipid biosynthetic process GO:0008610 179 0.013
icosanoid secretion GO:0032309 12 0.013
chemotaxis GO:0006935 247 0.013
cellular protein complex assembly GO:0043623 116 0.013
bone remodeling GO:0046849 53 0.013
cellular amide metabolic process GO:0043603 58 0.013
cognition GO:0050890 149 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
protein kinase b signaling GO:0043491 74 0.013
establishment of vesicle localization GO:0051650 81 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
digestive system development GO:0055123 200 0.013
regulation of myeloid cell apoptotic process GO:0033032 19 0.013
regulation of neuron differentiation GO:0045664 281 0.013
membrane lipid metabolic process GO:0006643 53 0.013
alpha beta t cell activation GO:0046631 91 0.013
stem cell differentiation GO:0048863 268 0.013
purine containing compound catabolic process GO:0072523 213 0.013
segmentation GO:0035282 93 0.013
regulation of leukocyte apoptotic process GO:2000106 56 0.013
positive regulation of cell migration GO:0030335 109 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
action potential GO:0001508 78 0.012
early endosome to late endosome transport GO:0045022 2 0.012
cellular water homeostasis GO:0009992 2 0.012
peptide secretion GO:0002790 114 0.012
regulated secretory pathway GO:0045055 32 0.012
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.012
regulation of ion transport GO:0043269 215 0.012
pigmentation GO:0043473 71 0.012
leukocyte proliferation GO:0070661 172 0.012
membrane fusion GO:0061025 38 0.012
cell type specific apoptotic process GO:0097285 268 0.012
neuronal action potential GO:0019228 54 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
peptide transport GO:0015833 133 0.012
camera type eye development GO:0043010 266 0.012
cytoplasmic transport GO:0016482 234 0.012
regulation of proteolysis GO:0030162 164 0.012
adult locomotory behavior GO:0008344 91 0.012
anatomical structure homeostasis GO:0060249 145 0.012
positive regulation of cell cycle process GO:0090068 61 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
positive regulation of nervous system development GO:0051962 221 0.012
glial cell differentiation GO:0010001 131 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
atp metabolic process GO:0046034 75 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
ras protein signal transduction GO:0007265 77 0.012
multicellular organismal signaling GO:0035637 91 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
forebrain development GO:0030900 302 0.011
amino acid transport GO:0006865 61 0.011
sensory perception GO:0007600 245 0.011
ear development GO:0043583 200 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
purine containing compound metabolic process GO:0072521 311 0.011
cellular response to acid chemical GO:0071229 68 0.011
regulation of kinase activity GO:0043549 249 0.011
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.011
spermatogenesis GO:0007283 284 0.011
epithelial cell development GO:0002064 159 0.011
positive regulation of kinase activity GO:0033674 155 0.011
wound healing GO:0042060 157 0.011
alcohol metabolic process GO:0006066 116 0.011
cardiac chamber development GO:0003205 108 0.011
extracellular matrix organization GO:0030198 147 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
mesoderm morphogenesis GO:0048332 64 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
organic acid biosynthetic process GO:0016053 86 0.011
respiratory system development GO:0060541 190 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
fatty acid transport GO:0015908 28 0.011
l amino acid transport GO:0015807 32 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
regulation of multi organism process GO:0043900 111 0.011
leukocyte migration GO:0050900 124 0.011
extracellular structure organization GO:0043062 148 0.011
protein maturation GO:0051604 176 0.011
inter male aggressive behavior GO:0002121 3 0.011
regulation of synapse structural plasticity GO:0051823 4 0.011
defense response to other organism GO:0098542 197 0.011
maintenance of location GO:0051235 89 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
sensory system development GO:0048880 3 0.011
regulation of vascular smooth muscle contraction GO:0003056 1 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
sequestering of calcium ion GO:0051208 18 0.010
smoothened signaling pathway GO:0007224 105 0.010
neuromuscular process GO:0050905 99 0.010
establishment of protein localization to membrane GO:0090150 54 0.010
response to inorganic substance GO:0010035 96 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
positive regulation of organelle organization GO:0010638 128 0.010
response to lipopolysaccharide GO:0032496 128 0.010
keratinocyte migration GO:0051546 3 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010
regulation of actin filament based process GO:0032970 99 0.010
regulation of mitotic cell cycle phase transition GO:1901990 73 0.010
lateral line system development GO:0048925 1 0.010
regulation of cytoskeleton organization GO:0051493 122 0.010
hydrogen ion transmembrane transport GO:1902600 25 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
myeloid cell homeostasis GO:0002262 114 0.010
monosaccharide metabolic process GO:0005996 106 0.010
b cell differentiation GO:0030183 78 0.010
regulation of coagulation GO:0050818 31 0.010
regulation of protein stability GO:0031647 52 0.010
regulation of systemic arterial blood pressure GO:0003073 61 0.010
regulation of cellular component size GO:0032535 121 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
negative regulation of secretion by cell GO:1903531 54 0.010
exosomal secretion GO:1990182 1 0.010

Degs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.276
inherited metabolic disorder DOID:655 0 0.276
disease of anatomical entity DOID:7 0 0.051
nervous system disease DOID:863 0 0.051
central nervous system disease DOID:331 0 0.023
brain disease DOID:936 0 0.023
lysosomal storage disease DOID:3211 0 0.022
neuropathy DOID:870 0 0.018
musculoskeletal system disease DOID:17 0 0.014
neuromuscular disease DOID:440 0 0.014
charcot marie tooth disease DOID:10595 0 0.014
epilepsy syndrome DOID:1826 0 0.013
electroclinical syndrome DOID:0050701 0 0.013
carbohydrate metabolic disorder DOID:2978 0 0.012
bone development disease DOID:0080006 0 0.011
bone disease DOID:0080001 0 0.011
connective tissue disease DOID:65 0 0.011