Mus musculus

7 known processes

Hacl1

2-hydroxyacyl-CoA lyase 1

(Aliases: Hpcl,1600020H07Rik,Phyh2)

Hacl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.320
Human Rat
monocarboxylic acid metabolic process GO:0032787 191 0.114
Human Rat
lipid catabolic process GO:0016042 69 0.090
Human Rat
cellular ketone metabolic process GO:0042180 84 0.088
organic hydroxy compound metabolic process GO:1901615 203 0.081
fatty acid metabolic process GO:0006631 121 0.079
Human Rat
cellular amino acid metabolic process GO:0006520 103 0.077
lipid biosynthetic process GO:0008610 179 0.075
cellular lipid metabolic process GO:0044255 323 0.073
Human Rat
fatty acid oxidation GO:0019395 28 0.068
Human Rat
regulation of cellular ketone metabolic process GO:0010565 66 0.067
small molecule catabolic process GO:0044282 71 0.064
Human Rat
sulfur compound metabolic process GO:0006790 100 0.060
small molecule biosynthetic process GO:0044283 132 0.059
cellular amine metabolic process GO:0044106 44 0.056
organic acid catabolic process GO:0016054 51 0.054
Human Rat
carboxylic acid catabolic process GO:0046395 51 0.053
Human Rat
cofactor metabolic process GO:0051186 80 0.053
amine metabolic process GO:0009308 45 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
fatty acid alpha oxidation GO:0001561 2 0.037
Human Rat
organic cyclic compound catabolic process GO:1901361 295 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
cation transport GO:0006812 399 0.031
thioester metabolic process GO:0035383 19 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
carboxylic acid biosynthetic process GO:0046394 86 0.030
macromolecule catabolic process GO:0009057 281 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.029
transmembrane transport GO:0055085 412 0.028
steroid metabolic process GO:0008202 119 0.028
alcohol metabolic process GO:0006066 116 0.026
organic acid biosynthetic process GO:0016053 86 0.026
response to organic cyclic compound GO:0014070 198 0.026
monocarboxylic acid catabolic process GO:0072329 27 0.026
Human Rat
heterocycle catabolic process GO:0046700 280 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
organonitrogen compound catabolic process GO:1901565 264 0.024
aromatic compound catabolic process GO:0019439 286 0.024
nucleotide metabolic process GO:0009117 332 0.024
acyl coa metabolic process GO:0006637 19 0.023
carbohydrate metabolic process GO:0005975 230 0.023
reactive nitrogen species metabolic process GO:2001057 0 0.023
acetate metabolic process GO:0006083 1 0.023
very long chain fatty acid catabolic process GO:0042760 2 0.023
fat cell differentiation GO:0045444 160 0.022
purine containing compound metabolic process GO:0072521 311 0.022
male gamete generation GO:0048232 285 0.022
cellular alcohol metabolic process GO:0044107 3 0.021
sterol metabolic process GO:0016125 58 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.020
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.020
glycerolipid metabolic process GO:0046486 122 0.020
cellular alcohol biosynthetic process GO:0044108 3 0.020
protein maturation GO:0051604 176 0.020
peptidyl amino acid modification GO:0018193 336 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
response to organonitrogen compound GO:0010243 246 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
protein processing GO:0016485 163 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
anion transport GO:0006820 177 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
innate immune response GO:0045087 157 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
cellular lipid catabolic process GO:0044242 52 0.018
Human Rat
ion transmembrane transport GO:0034220 361 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
lipid oxidation GO:0034440 29 0.018
Human Rat
regulation of organelle organization GO:0033043 289 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
spermatogenesis GO:0007283 284 0.018
maintenance of location GO:0051235 89 0.018
regulation of hormone levels GO:0010817 211 0.018
protein catabolic process GO:0030163 221 0.018
lipid modification GO:0030258 65 0.018
Human Rat
fatty acid beta oxidation GO:0006635 16 0.018
cation transmembrane transport GO:0098655 266 0.017
apoptotic signaling pathway GO:0097190 306 0.017
intracellular protein transport GO:0006886 204 0.017
organic hydroxy compound biosynthetic process GO:1901617 77 0.016
membrane organization GO:0061024 245 0.016
regulation of cytokine production GO:0001817 266 0.016
protein oligomerization GO:0051259 67 0.016
Human
purine nucleoside metabolic process GO:0042278 241 0.016
cellular modified amino acid metabolic process GO:0006575 63 0.016
coenzyme a metabolic process GO:0015936 8 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
striated muscle tissue development GO:0014706 293 0.016
mitochondrion organization GO:0007005 134 0.015
ossification GO:0001503 216 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
organic anion transport GO:0015711 137 0.015
microtubule based process GO:0007017 236 0.015
fatty acid catabolic process GO:0009062 25 0.015
Human Rat
ribonucleotide metabolic process GO:0009259 291 0.015
protein homooligomerization GO:0051260 43 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
glucose homeostasis GO:0042593 128 0.015
dna metabolic process GO:0006259 303 0.015
nucleoside metabolic process GO:0009116 246 0.015
nucleoside bisphosphate metabolic process GO:0033865 9 0.015
regulation of membrane potential GO:0042391 192 0.014
sensory perception GO:0007600 245 0.014
t cell activation GO:0042110 289 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
organelle fission GO:0048285 170 0.014
renal system development GO:0072001 225 0.014
regulation of cell activation GO:0050865 289 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
coenzyme catabolic process GO:0009109 5 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
xenobiotic catabolic process GO:0042178 1 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
regulation of protein maturation GO:1903317 96 0.013
ras protein signal transduction GO:0007265 77 0.013
cell type specific apoptotic process GO:0097285 268 0.013
cellular protein catabolic process GO:0044257 155 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
glucose metabolic process GO:0006006 92 0.013
cytokine production GO:0001816 319 0.013
sensory organ morphogenesis GO:0090596 242 0.013
cellular amino acid catabolic process GO:0009063 25 0.013
cytoplasmic transport GO:0016482 234 0.013
nitrogen compound transport GO:0071705 271 0.013
regulation of intracellular transport GO:0032386 159 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
nucleotide catabolic process GO:0009166 217 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
skeletal system development GO:0001501 356 0.013
nucleoside catabolic process GO:0009164 206 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
organophosphate catabolic process GO:0046434 232 0.013
leukocyte differentiation GO:0002521 342 0.013
positive regulation of protein modification process GO:0031401 299 0.013
fatty acid derivative metabolic process GO:1901568 33 0.013
cholesterol metabolic process GO:0008203 56 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
purine containing compound catabolic process GO:0072523 213 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
regulation of homeostatic process GO:0032844 182 0.013
fat soluble vitamin biosynthetic process GO:0042362 4 0.012
hexose metabolic process GO:0019318 98 0.012
immune effector process GO:0002252 321 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
steroid biosynthetic process GO:0006694 47 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
cellular homeostasis GO:0019725 240 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
response to extracellular stimulus GO:0009991 127 0.012
protein localization to organelle GO:0033365 185 0.012
nuclear division GO:0000280 158 0.012
negative regulation of molecular function GO:0044092 258 0.012
regulation of cell cycle GO:0051726 281 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
lipid localization GO:0010876 126 0.012
regulation of transferase activity GO:0051338 263 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
carbohydrate homeostasis GO:0033500 128 0.012
regulation of secretion GO:0051046 274 0.012
homeostasis of number of cells GO:0048872 210 0.011
lipid transport GO:0006869 98 0.011
midgut development GO:0007494 4 0.011
regulation of t cell activation GO:0050863 170 0.011
regulation of secretion by cell GO:1903530 249 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
regulation of protein localization GO:0032880 231 0.011
cellular chemical homeostasis GO:0055082 215 0.011
ear development GO:0043583 200 0.011
fatty acid biosynthetic process GO:0006633 41 0.011
regulation of protein processing GO:0070613 96 0.011
substantia nigra development GO:0021762 2 0.011
cofactor catabolic process GO:0051187 6 0.011
regulation of mapk cascade GO:0043408 248 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
inflammatory response GO:0006954 244 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
skin development GO:0043588 220 0.011
response to peptide GO:1901652 136 0.011
cellular amide metabolic process GO:0043603 58 0.011
transmission of nerve impulse GO:0019226 76 0.011
response to oxidative stress GO:0006979 123 0.011
regulation of defense response GO:0031347 233 0.011
regulation of cellular response to stress GO:0080135 159 0.011
skeletal system morphogenesis GO:0048705 203 0.011
muscle cell differentiation GO:0042692 261 0.011
response to lipopolysaccharide GO:0032496 128 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
multicellular organismal signaling GO:0035637 91 0.011
negative regulation of protein modification process GO:0031400 163 0.011
negative regulation of immune system process GO:0002683 209 0.011
peptide metabolic process GO:0006518 46 0.011
response to nutrient levels GO:0031667 109 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
divalent inorganic cation transport GO:0072511 178 0.011
chemotaxis GO:0006935 247 0.011
neuronal action potential GO:0019228 54 0.011
protein ubiquitination GO:0016567 171 0.011
germ cell development GO:0007281 185 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
endomembrane system organization GO:0010256 147 0.010
muscle tissue development GO:0060537 308 0.010
pyrimidine containing compound catabolic process GO:0072529 3 0.010
purine ribonucleoside catabolic process GO:0046130 205 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
nadph regeneration GO:0006740 2 0.010
smoothened signaling pathway GO:0007224 105 0.010

Hacl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.080
inherited metabolic disorder DOID:655 0 0.049
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.014
immune system disease DOID:2914 0 0.013
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
eye disease DOID:5614 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011