Mus musculus

10 known processes

Dgcr8

DiGeorge syndrome critical region gene 8

(Aliases: D16H22S1742E,N41,D16Wis2,D16H22S788E,Gy1,Vo59c07)

Dgcr8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone methylation GO:0016571 71 0.211
cellular amine metabolic process GO:0044106 44 0.107
regulation of cellular amine metabolic process GO:0033238 20 0.098
amine metabolic process GO:0009308 45 0.096
protein methylation GO:0006479 81 0.092
regulation of cellular amino acid metabolic process GO:0006521 5 0.083
cellular amino acid metabolic process GO:0006520 103 0.074
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.073
dna metabolic process GO:0006259 303 0.071
histone lysine methylation GO:0034968 50 0.066
methylation GO:0032259 134 0.064
cellular ketone metabolic process GO:0042180 84 0.064
protein modification by small protein conjugation GO:0032446 187 0.062
regulation of cellular ketone metabolic process GO:0010565 66 0.062
peptidyl amino acid modification GO:0018193 336 0.057
chromatin organization GO:0006325 206 0.056
organelle fission GO:0048285 170 0.056
regulation of cell cycle GO:0051726 281 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.050
nuclear division GO:0000280 158 0.049
protein modification by small protein conjugation or removal GO:0070647 207 0.049
ras protein signal transduction GO:0007265 77 0.048
cellular nitrogen compound catabolic process GO:0044270 280 0.047
protein alkylation GO:0008213 81 0.047
mitotic cell cycle GO:0000278 195 0.042
heterocycle catabolic process GO:0046700 280 0.042
cellular response to dna damage stimulus GO:0006974 207 0.041
small gtpase mediated signal transduction GO:0007264 97 0.041
macromolecule methylation GO:0043414 120 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
regulation of organelle organization GO:0033043 289 0.038
aromatic compound catabolic process GO:0019439 286 0.037
histone modification GO:0016570 159 0.036
mitotic cell cycle process GO:1903047 159 0.036
ribonucleoside triphosphate metabolic process GO:0009199 220 0.035
glycosyl compound metabolic process GO:1901657 246 0.034
cytoplasmic transport GO:0016482 234 0.034
ribonucleotide metabolic process GO:0009259 291 0.034
chromatin modification GO:0016568 187 0.034
regulation of cell activation GO:0050865 289 0.033
microtubule based process GO:0007017 236 0.032
skeletal system development GO:0001501 356 0.031
spermatogenesis GO:0007283 284 0.030
cellular macromolecule catabolic process GO:0044265 206 0.030
organonitrogen compound catabolic process GO:1901565 264 0.030
ribonucleoside metabolic process GO:0009119 245 0.029
microtubule cytoskeleton organization GO:0000226 157 0.028
covalent chromatin modification GO:0016569 163 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
dna repair GO:0006281 107 0.028
male gamete generation GO:0048232 285 0.028
negative regulation of cellular component organization GO:0051129 194 0.027
cellular lipid metabolic process GO:0044255 323 0.027
macromolecule catabolic process GO:0009057 281 0.027
protein localization to organelle GO:0033365 185 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
nucleotide metabolic process GO:0009117 332 0.026
transmembrane transport GO:0055085 412 0.025
regulation of cell cycle process GO:0010564 160 0.025
fertilization GO:0009566 127 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
membrane organization GO:0061024 245 0.024
nitrogen compound transport GO:0071705 271 0.024
intracellular protein transport GO:0006886 204 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
modification dependent protein catabolic process GO:0019941 133 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
stem cell differentiation GO:0048863 268 0.023
purine nucleotide catabolic process GO:0006195 211 0.023
regulation of intracellular transport GO:0032386 159 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
positive regulation of organelle organization GO:0010638 128 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
cation transport GO:0006812 399 0.023
protein polymerization GO:0051258 57 0.023
nucleoside catabolic process GO:0009164 206 0.022
rho protein signal transduction GO:0007266 32 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
nuclear transport GO:0051169 139 0.022
regulation of cellular catabolic process GO:0031329 242 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
protein catabolic process GO:0030163 221 0.021
cellular protein catabolic process GO:0044257 155 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
regulation of membrane potential GO:0042391 192 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
guanosine containing compound catabolic process GO:1901069 144 0.021
immune effector process GO:0002252 321 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
organophosphate catabolic process GO:0046434 232 0.020
ion transmembrane transport GO:0034220 361 0.020
purine containing compound metabolic process GO:0072521 311 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
protein ubiquitination GO:0016567 171 0.020
nucleoside metabolic process GO:0009116 246 0.020
protein targeting GO:0006605 143 0.020
purine containing compound catabolic process GO:0072523 213 0.020
spermatid development GO:0007286 108 0.020
lymphocyte mediated immunity GO:0002449 139 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.019
leukocyte differentiation GO:0002521 342 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
dephosphorylation GO:0016311 129 0.019
gene silencing GO:0016458 38 0.019
Human Fly
regulation of histone methylation GO:0031060 30 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
inflammatory response GO:0006954 244 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
cation transmembrane transport GO:0098655 266 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
lipid biosynthetic process GO:0008610 179 0.018
cell adhesion GO:0007155 329 0.018
nucleocytoplasmic transport GO:0006913 139 0.017
organelle assembly GO:0070925 177 0.017
negative regulation of organelle organization GO:0010639 90 0.017
negative regulation of mitotic cell cycle GO:0045930 58 0.017
lymphocyte differentiation GO:0030098 242 0.017
cytokine production GO:0001816 319 0.017
positive regulation of protein modification process GO:0031401 299 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
cellular homeostasis GO:0019725 240 0.017
muscle tissue development GO:0060537 308 0.017
regulation of protein localization GO:0032880 231 0.017
mitotic nuclear division GO:0007067 48 0.017
response to organonitrogen compound GO:0010243 246 0.017
compound eye development GO:0048749 1 0.017
regulation of mitotic cell cycle phase transition GO:1901990 73 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
multicellular organismal signaling GO:0035637 91 0.016
leukocyte activation involved in immune response GO:0002366 126 0.016
cellular protein complex assembly GO:0043623 116 0.016
cell activation involved in immune response GO:0002263 126 0.016
positive regulation of cellular component biogenesis GO:0044089 94 0.016
protein localization to nucleus GO:0034504 121 0.016
ossification GO:0001503 216 0.016
homeostasis of number of cells GO:0048872 210 0.016
response to light stimulus GO:0009416 135 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
endomembrane system organization GO:0010256 147 0.016
peptidyl lysine trimethylation GO:0018023 12 0.016
regulation of chromosome organization GO:0033044 83 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
histone h3 k4 methylation GO:0051568 23 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
leukocyte mediated immunity GO:0002443 174 0.016
gtp metabolic process GO:0046039 144 0.015
camera type eye development GO:0043010 266 0.015
meiotic nuclear division GO:0007126 115 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.015
protein import GO:0017038 101 0.015
anatomical structure homeostasis GO:0060249 145 0.015
blood vessel morphogenesis GO:0048514 285 0.015
spermatid differentiation GO:0048515 115 0.015
action potential GO:0001508 78 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
meiotic cell cycle GO:0051321 122 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
regulation of histone h3 k36 methylation GO:0000414 1 0.015
regulation of proteolysis GO:0030162 164 0.015
blastocyst development GO:0001824 80 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
regulation of cytokine production GO:0001817 266 0.015
sensory perception GO:0007600 245 0.015
nucleotide catabolic process GO:0009166 217 0.015
carbohydrate metabolic process GO:0005975 230 0.015
oxidation reduction process GO:0055114 342 0.015
regulation of protein transport GO:0051223 163 0.014
respiratory system development GO:0060541 190 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
protein maturation GO:0051604 176 0.014
striated muscle tissue development GO:0014706 293 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
multicellular organism growth GO:0035264 161 0.014
germ cell development GO:0007281 185 0.014
Fly
positive regulation of cellular catabolic process GO:0031331 148 0.014
t cell activation GO:0042110 289 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
dna endoreduplication GO:0042023 4 0.014
heart morphogenesis GO:0003007 178 0.014
regulation of hydrolase activity GO:0051336 246 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
Human Fly
regulation of hormone levels GO:0010817 211 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
double strand break repair GO:0006302 48 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
connective tissue development GO:0061448 179 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
regulation of protein complex assembly GO:0043254 83 0.014
regulation of homeostatic process GO:0032844 182 0.014
peptidyl lysine methylation GO:0018022 29 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
nuclear import GO:0051170 95 0.014
positive regulation of cell activation GO:0050867 158 0.014
divalent metal ion transport GO:0070838 172 0.014
apoptotic signaling pathway GO:0097190 306 0.014
regulation of protein processing GO:0070613 96 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
regulation of cell projection organization GO:0031344 206 0.013
regionalization GO:0003002 337 0.013
female gamete generation GO:0007292 74 0.013
Fly
mapk cascade GO:0000165 281 0.013
cilium assembly GO:0042384 81 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
actin filament organization GO:0007015 113 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
cellular response to lipid GO:0071396 145 0.013
organic anion transport GO:0015711 137 0.013
developmental maturation GO:0021700 193 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
single fertilization GO:0007338 82 0.013
response to insulin GO:0032868 100 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
cellularization GO:0007349 1 0.013
regulation of gtp catabolic process GO:0033124 113 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
regulation of protein catabolic process GO:0042176 108 0.013
meiotic cell cycle process GO:1903046 77 0.013
response to radiation GO:0009314 165 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
heterochromatin organization GO:0070828 4 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
respiratory tube development GO:0030323 167 0.012
angiogenesis GO:0001525 201 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
b cell activation GO:0042113 161 0.012
negative regulation of cell cycle GO:0045786 123 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
myeloid cell differentiation GO:0030099 233 0.012
bone development GO:0060348 120 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
divalent inorganic cation transport GO:0072511 178 0.012
negative regulation of immune system process GO:0002683 209 0.012
regulation of nuclear division GO:0051783 56 0.012
anion transport GO:0006820 177 0.012
peptide transport GO:0015833 133 0.012
organelle localization GO:0051640 179 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
regulation of secretion GO:0051046 274 0.012
regulation of chromatin silencing GO:0031935 2 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
negative regulation of protein modification process GO:0031400 163 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012
digestive system development GO:0055123 200 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
axonogenesis GO:0007409 274 0.012
regulation of response to wounding GO:1903034 189 0.012
mitotic sister chromatid segregation GO:0000070 14 0.012
regulation of rho protein signal transduction GO:0035023 71 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.012
skeletal muscle organ development GO:0060538 163 0.012
positive regulation of cell cycle process GO:0090068 61 0.012
oocyte construction GO:0007308 2 0.012
leukocyte proliferation GO:0070661 172 0.012
transmission of nerve impulse GO:0019226 76 0.012
fat cell differentiation GO:0045444 160 0.012
dna recombination GO:0006310 92 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
maintenance of location GO:0051235 89 0.012
positive regulation of cell development GO:0010720 237 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
regulation of anatomical structure size GO:0090066 178 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
cation homeostasis GO:0055080 212 0.011
positive regulation of immune effector process GO:0002699 107 0.011
actin cytoskeleton organization GO:0030036 220 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
retina development in camera type eye GO:0060041 119 0.011
tissue homeostasis GO:0001894 115 0.011
peptidyl lysine modification GO:0018205 77 0.011
neural tube development GO:0021915 160 0.011
regulation of neuron differentiation GO:0045664 281 0.011
small molecule biosynthetic process GO:0044283 132 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
response to growth factor GO:0070848 198 0.011
single organism cell adhesion GO:0098602 156 0.011
single organism nuclear import GO:1902593 95 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
regulation of t cell activation GO:0050863 170 0.011
gland development GO:0048732 330 0.011
regulation of inflammatory response GO:0050727 147 0.011
regulation of secretion by cell GO:1903530 249 0.011
regulation of ossification GO:0030278 112 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
regulation of cellular response to stress GO:0080135 159 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
digestive tract development GO:0048565 190 0.011
skeletal system morphogenesis GO:0048705 203 0.011
cilium morphogenesis GO:0060271 102 0.011
cell division GO:0051301 120 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
alcohol metabolic process GO:0006066 116 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
cellular ion homeostasis GO:0006873 165 0.011
regulation of ion transport GO:0043269 215 0.011
response to lipopolysaccharide GO:0032496 128 0.011
cell maturation GO:0048469 127 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
intracellular mrna localization GO:0008298 4 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
forebrain development GO:0030900 302 0.011
sensory organ morphogenesis GO:0090596 242 0.011
digestive tract morphogenesis GO:0048546 147 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
dendrite development GO:0016358 115 0.010
gastrulation GO:0007369 116 0.010
lateral inhibition GO:0046331 1 0.010
gtp catabolic process GO:0006184 143 0.010
sequestering of metal ion GO:0051238 19 0.010
regulation of actin filament based process GO:0032970 99 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
localization within membrane GO:0051668 4 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
amide transport GO:0042886 138 0.010
cofactor metabolic process GO:0051186 80 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
regulation of microtubule based process GO:0032886 52 0.010
chromosome segregation GO:0007059 48 0.010
calcium ion transport GO:0006816 159 0.010
oocyte axis specification GO:0007309 2 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
hormone secretion GO:0046879 128 0.010
phospholipid metabolic process GO:0006644 87 0.010
positive regulation of cell death GO:0010942 224 0.010

Dgcr8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
immune system disease DOID:2914 0 0.018
central nervous system disease DOID:331 0 0.017
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
hematopoietic system disease DOID:74 0 0.012
neurodegenerative disease DOID:1289 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011