Mus musculus

22 known processes

Pla2g16

phospholipase A2, group XVI

(Aliases: C78643,MLP-3,Hrev107,Hrasls3)

Pla2g16 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.110
cellular ketone metabolic process GO:0042180 84 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.048
cellular amine metabolic process GO:0044106 44 0.046
transmembrane transport GO:0055085 412 0.044
negative regulation of molecular function GO:0044092 258 0.043
monocarboxylic acid metabolic process GO:0032787 191 0.043
cellular amino acid metabolic process GO:0006520 103 0.041
cytokine production GO:0001816 319 0.038
apoptotic signaling pathway GO:0097190 306 0.036
cation transport GO:0006812 399 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
inflammatory response GO:0006954 244 0.034
negative regulation of phosphorus metabolic process GO:0010563 184 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.033
amine metabolic process GO:0009308 45 0.033
negative regulation of phosphate metabolic process GO:0045936 184 0.032
innate immune response GO:0045087 157 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.030
cellular lipid metabolic process GO:0044255 323 0.030
negative regulation of phosphorylation GO:0042326 166 0.030
immune effector process GO:0002252 321 0.029
regulation of hydrolase activity GO:0051336 246 0.029
nucleotide metabolic process GO:0009117 332 0.029
regulation of defense response GO:0031347 233 0.029
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
regulation of transferase activity GO:0051338 263 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
negative regulation of protein metabolic process GO:0051248 282 0.026
intracellular protein transport GO:0006886 204 0.026
regulation of cytokine production GO:0001817 266 0.026
fatty acid metabolic process GO:0006631 121 0.026
nitrogen compound transport GO:0071705 271 0.026
dna metabolic process GO:0006259 303 0.026
regulation of protein localization GO:0032880 231 0.026
mapk cascade GO:0000165 281 0.026
regulation of mapk cascade GO:0043408 248 0.025
spermatogenesis GO:0007283 284 0.025
regulation of apoptotic signaling pathway GO:2001233 197 0.025
myeloid cell differentiation GO:0030099 233 0.025
positive regulation of protein modification process GO:0031401 299 0.024
regulation of organelle organization GO:0033043 289 0.024
purine containing compound metabolic process GO:0072521 311 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
protein maturation GO:0051604 176 0.023
cytoplasmic transport GO:0016482 234 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
purine nucleotide metabolic process GO:0006163 302 0.022
negative regulation of protein phosphorylation GO:0001933 126 0.022
male gamete generation GO:0048232 285 0.022
ion transmembrane transport GO:0034220 361 0.022
negative regulation of protein modification process GO:0031400 163 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
regulation of protein kinase activity GO:0045859 232 0.022
cellular homeostasis GO:0019725 240 0.022
protein localization to organelle GO:0033365 185 0.021
carbohydrate metabolic process GO:0005975 230 0.021
i kappab kinase nf kappab signaling GO:0007249 85 0.021
regulation of intracellular transport GO:0032386 159 0.021
regulation of peptidase activity GO:0052547 96 0.021
protein processing GO:0016485 163 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
aromatic compound catabolic process GO:0019439 286 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
synaptic transmission GO:0007268 329 0.021
regulation of kinase activity GO:0043549 249 0.020
cation transmembrane transport GO:0098655 266 0.020
membrane organization GO:0061024 245 0.020
positive regulation of cell death GO:0010942 224 0.020
mitochondrion organization GO:0007005 134 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
cofactor metabolic process GO:0051186 80 0.019
regulation of ion transport GO:0043269 215 0.019
t cell activation GO:0042110 289 0.019
macromolecule catabolic process GO:0009057 281 0.019
small molecule biosynthetic process GO:0044283 132 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
response to lipopolysaccharide GO:0032496 128 0.019
leukocyte differentiation GO:0002521 342 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
regulation of membrane potential GO:0042391 192 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
regulation of proteolysis GO:0030162 164 0.018
cellular chemical homeostasis GO:0055082 215 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
heterocycle catabolic process GO:0046700 280 0.018
actin cytoskeleton organization GO:0030036 220 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
striated muscle tissue development GO:0014706 293 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
regulation of hormone levels GO:0010817 211 0.017
sulfur compound metabolic process GO:0006790 100 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
anion transport GO:0006820 177 0.017
regulation of homeostatic process GO:0032844 182 0.017
response to organic cyclic compound GO:0014070 198 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
maintenance of location GO:0051235 89 0.017
protein catabolic process GO:0030163 221 0.017
peptidyl amino acid modification GO:0018193 336 0.017
lipid biosynthetic process GO:0008610 179 0.017
inorganic cation transmembrane transport GO:0098662 207 0.016
response to organonitrogen compound GO:0010243 246 0.016
lymphocyte proliferation GO:0046651 164 0.016
regulation of transmembrane transport GO:0034762 128 0.016
response to oxidative stress GO:0006979 123 0.016
regulation of response to wounding GO:1903034 189 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
cation homeostasis GO:0055080 212 0.016
regulation of secretion GO:0051046 274 0.016
regulation of protein transport GO:0051223 163 0.016
regulation of cell activation GO:0050865 289 0.016
microtubule based process GO:0007017 236 0.016
cell type specific apoptotic process GO:0097285 268 0.016
negative regulation of immune system process GO:0002683 209 0.015
lymphocyte differentiation GO:0030098 242 0.015
fat cell differentiation GO:0045444 160 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
regulation of secretion by cell GO:1903530 249 0.015
cellular response to lipid GO:0071396 145 0.015
ras protein signal transduction GO:0007265 77 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
regulation of cellular response to stress GO:0080135 159 0.015
sensory perception GO:0007600 245 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
divalent inorganic cation transport GO:0072511 178 0.015
negative regulation of transferase activity GO:0051348 85 0.015
cellular response to oxidative stress GO:0034599 76 0.015
leukocyte mediated immunity GO:0002443 174 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.014
anatomical structure homeostasis GO:0060249 145 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
protein targeting GO:0006605 143 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
amide transport GO:0042886 138 0.014
cellular protein complex assembly GO:0043623 116 0.014
muscle tissue development GO:0060537 308 0.014
nuclear transport GO:0051169 139 0.014
metal ion homeostasis GO:0055065 189 0.014
homeostasis of number of cells GO:0048872 210 0.014
cell adhesion GO:0007155 329 0.014
organic acid biosynthetic process GO:0016053 86 0.013
response to inorganic substance GO:0010035 96 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
carboxylic acid transport GO:0046942 100 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
nucleoside metabolic process GO:0009116 246 0.013
divalent metal ion transport GO:0070838 172 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
negative regulation of kinase activity GO:0033673 81 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
response to acid chemical GO:0001101 111 0.013
alcohol metabolic process GO:0006066 116 0.013
glycerolipid metabolic process GO:0046486 122 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
antigen processing and presentation GO:0019882 47 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
lipid catabolic process GO:0016042 69 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
nucleotide catabolic process GO:0009166 217 0.012
regulation of t cell activation GO:0050863 170 0.012
neuron death GO:0070997 154 0.012
organic acid transport GO:0015849 101 0.012
organophosphate catabolic process GO:0046434 232 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
protein ubiquitination GO:0016567 171 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
circulatory system process GO:0003013 197 0.012
regulation of cell cycle GO:0051726 281 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
positive regulation of cytokine production GO:0001819 174 0.012
protein localization to nucleus GO:0034504 121 0.012
protein oligomerization GO:0051259 67 0.012
extracellular matrix organization GO:0030198 147 0.012
cellular ion homeostasis GO:0006873 165 0.012
response to radiation GO:0009314 165 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
action potential GO:0001508 78 0.012
organic anion transport GO:0015711 137 0.012
leukocyte proliferation GO:0070661 172 0.012
epithelial cell development GO:0002064 159 0.012
cellular modified amino acid metabolic process GO:0006575 63 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
protein localization to membrane GO:0072657 108 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
regulation of cellular component biogenesis GO:0044087 181 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
organelle localization GO:0051640 179 0.011
lipid modification GO:0030258 65 0.011
peptide transport GO:0015833 133 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
cellular response to acid chemical GO:0071229 68 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
blood circulation GO:0008015 195 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
purine containing compound catabolic process GO:0072523 213 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
interleukin 8 production GO:0032637 4 0.011
regulation of protein processing GO:0070613 96 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
rho protein signal transduction GO:0007266 32 0.011
extracellular structure organization GO:0043062 148 0.011
calcium ion homeostasis GO:0055074 127 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
sensory organ morphogenesis GO:0090596 242 0.011
positive regulation of kinase activity GO:0033674 155 0.011
gland development GO:0048732 330 0.011
positive regulation of mapk cascade GO:0043410 170 0.010
monocarboxylic acid biosynthetic process GO:0072330 61 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
skeletal muscle organ development GO:0060538 163 0.010
positive regulation of transferase activity GO:0051347 167 0.010
regulation of neuron differentiation GO:0045664 281 0.010
regulation of binding GO:0051098 111 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
regulation of inflammatory response GO:0050727 147 0.010
nucleoside catabolic process GO:0009164 206 0.010
skeletal system development GO:0001501 356 0.010
muscle cell differentiation GO:0042692 261 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
regulation of protein maturation GO:1903317 96 0.010
positive regulation of proteolysis GO:0045862 85 0.010
forebrain development GO:0030900 302 0.010
regulation of system process GO:0044057 200 0.010
negative regulation of hydrolase activity GO:0051346 71 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
response to extracellular stimulus GO:0009991 127 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
coenzyme metabolic process GO:0006732 52 0.010
negative regulation of protein processing GO:0010955 79 0.010
carbohydrate homeostasis GO:0033500 128 0.010
urogenital system development GO:0001655 261 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
positive regulation of cell development GO:0010720 237 0.010

Pla2g16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.025
disease of anatomical entity DOID:7 0 0.025
disease of metabolism DOID:0014667 0 0.017
immune system disease DOID:2914 0 0.014
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
central nervous system disease DOID:331 0 0.012
inherited metabolic disorder DOID:655 0 0.011