Mus musculus

166 known processes

Sik1

salt inducible kinase 1

(Aliases: Sik,Snf1lk,Msk)

Sik1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.197
amine metabolic process GO:0009308 45 0.155
mapk cascade GO:0000165 281 0.123
muscle tissue development GO:0060537 308 0.119
organic cyclic compound catabolic process GO:1901361 295 0.113
regulation of cellular amine metabolic process GO:0033238 20 0.112
cellular amine metabolic process GO:0044106 44 0.107
fat cell differentiation GO:0045444 160 0.107
negative regulation of cellular protein metabolic process GO:0032269 247 0.092
cellular ketone metabolic process GO:0042180 84 0.092
negative regulation of cell proliferation GO:0008285 296 0.091
regulation of mapk cascade GO:0043408 248 0.090
negative regulation of molecular function GO:0044092 258 0.086
regulation of cellular catabolic process GO:0031329 242 0.085
ribonucleoside triphosphate catabolic process GO:0009203 199 0.083
negative regulation of protein metabolic process GO:0051248 282 0.082
heterocycle catabolic process GO:0046700 280 0.080
response to organonitrogen compound GO:0010243 246 0.077
Mouse
positive regulation of protein modification process GO:0031401 299 0.076
aromatic compound catabolic process GO:0019439 286 0.075
regulation of cellular ketone metabolic process GO:0010565 66 0.073
regulation of hydrolase activity GO:0051336 246 0.072
leukocyte differentiation GO:0002521 342 0.072
positive regulation of cell development GO:0010720 237 0.072
striated muscle tissue development GO:0014706 293 0.069
forebrain development GO:0030900 302 0.068
blood vessel morphogenesis GO:0048514 285 0.066
cell adhesion GO:0007155 329 0.066
ras protein signal transduction GO:0007265 77 0.065
nucleoside phosphate metabolic process GO:0006753 338 0.065
purine nucleotide catabolic process GO:0006195 211 0.065
gland development GO:0048732 330 0.065
organonitrogen compound catabolic process GO:1901565 264 0.063
regulation of nucleotide metabolic process GO:0006140 169 0.063
macromolecule catabolic process GO:0009057 281 0.063
response to radiation GO:0009314 165 0.062
positive regulation of cellular catabolic process GO:0031331 148 0.062
cellular amino acid metabolic process GO:0006520 103 0.062
myeloid cell differentiation GO:0030099 233 0.060
cellular macromolecule catabolic process GO:0044265 206 0.060
cytokine production GO:0001816 319 0.060
angiogenesis GO:0001525 201 0.060
cellular nitrogen compound catabolic process GO:0044270 280 0.060
regulation of protein kinase activity GO:0045859 232 0.060
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.059
peptidyl amino acid modification GO:0018193 336 0.058
purine nucleotide metabolic process GO:0006163 302 0.058
urogenital system development GO:0001655 261 0.058
ion transmembrane transport GO:0034220 361 0.058
positive regulation of programmed cell death GO:0043068 218 0.057
Human
small gtpase mediated signal transduction GO:0007264 97 0.057
cell type specific apoptotic process GO:0097285 268 0.055
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.055
Mouse
respiratory system development GO:0060541 190 0.055
nucleobase containing small molecule metabolic process GO:0055086 352 0.055
nucleotide metabolic process GO:0009117 332 0.054
ribonucleoside triphosphate metabolic process GO:0009199 220 0.053
carbohydrate derivative catabolic process GO:1901136 231 0.053
response to lipopolysaccharide GO:0032496 128 0.053
synaptic transmission GO:0007268 329 0.053
inflammatory response GO:0006954 244 0.052
nucleoside triphosphate metabolic process GO:0009141 230 0.052
purine containing compound metabolic process GO:0072521 311 0.051
regionalization GO:0003002 337 0.051
regulation of kinase activity GO:0043549 249 0.051
positive regulation of mapk cascade GO:0043410 170 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.050
purine ribonucleotide catabolic process GO:0009154 208 0.049
ossification GO:0001503 216 0.049
Mouse
positive regulation of cell death GO:0010942 224 0.049
Human
cellular response to organonitrogen compound GO:0071417 145 0.048
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.048
regulation of organelle organization GO:0033043 289 0.048
regulation of cell cycle GO:0051726 281 0.047
regulation of transferase activity GO:0051338 263 0.047
muscle system process GO:0003012 141 0.047
lymphocyte differentiation GO:0030098 242 0.047
apoptotic signaling pathway GO:0097190 306 0.047
positive regulation of protein phosphorylation GO:0001934 242 0.046
purine ribonucleotide metabolic process GO:0009150 290 0.046
regulation of apoptotic signaling pathway GO:2001233 197 0.046
ribose phosphate metabolic process GO:0019693 291 0.046
ribonucleoside catabolic process GO:0042454 206 0.046
ameboidal type cell migration GO:0001667 128 0.046
purine ribonucleoside metabolic process GO:0046128 241 0.046
regulation of secretion by cell GO:1903530 249 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
purine containing compound catabolic process GO:0072523 213 0.045
regulation of cytokine production GO:0001817 266 0.045
transmembrane transport GO:0055085 412 0.045
ribonucleotide catabolic process GO:0009261 208 0.045
nitrogen compound transport GO:0071705 271 0.045
regulation of epithelial cell proliferation GO:0050678 141 0.045
t cell activation GO:0042110 289 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
rho protein signal transduction GO:0007266 32 0.044
epithelial cell proliferation GO:0050673 174 0.043
cellular lipid metabolic process GO:0044255 323 0.043
nucleoside catabolic process GO:0009164 206 0.043
regulation of neuron differentiation GO:0045664 281 0.043
nucleotide catabolic process GO:0009166 217 0.042
placenta development GO:0001890 140 0.042
blood circulation GO:0008015 195 0.042
purine nucleoside metabolic process GO:0042278 241 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
organophosphate catabolic process GO:0046434 232 0.042
regulation of secretion GO:0051046 274 0.041
purine nucleoside catabolic process GO:0006152 205 0.041
cytoplasmic transport GO:0016482 234 0.041
kidney development GO:0001822 213 0.041
regulation of system process GO:0044057 200 0.040
single organism cell adhesion GO:0098602 156 0.039
regulation of defense response GO:0031347 233 0.039
axonogenesis GO:0007409 274 0.039
skeletal muscle organ development GO:0060538 163 0.039
cation transmembrane transport GO:0098655 266 0.038
cellular response to growth factor stimulus GO:0071363 197 0.038
Worm
positive regulation of nervous system development GO:0051962 221 0.038
anion transport GO:0006820 177 0.038
cellular homeostasis GO:0019725 240 0.038
regulation of fat cell differentiation GO:0045598 81 0.038
gliogenesis GO:0042063 141 0.038
response to molecule of bacterial origin GO:0002237 143 0.037
ribonucleoside metabolic process GO:0009119 245 0.037
nucleoside phosphate catabolic process GO:1901292 222 0.037
purine nucleoside triphosphate catabolic process GO:0009146 203 0.037
renal system development GO:0072001 225 0.037
wnt signaling pathway GO:0016055 188 0.037
negative regulation of phosphorylation GO:0042326 166 0.037
response to oxidative stress GO:0006979 123 0.036
gtp metabolic process GO:0046039 144 0.036
multicellular organismal homeostasis GO:0048871 164 0.036
glycosyl compound metabolic process GO:1901657 246 0.036
cation transport GO:0006812 399 0.036
Rat
anion transmembrane transport GO:0098656 71 0.036
glycosyl compound catabolic process GO:1901658 206 0.036
nucleoside metabolic process GO:0009116 246 0.036
negative regulation of protein phosphorylation GO:0001933 126 0.036
respiratory tube development GO:0030323 167 0.036
gtp catabolic process GO:0006184 143 0.035
stem cell development GO:0048864 219 0.035
regulation of cell motility GO:2000145 236 0.035
organic anion transport GO:0015711 137 0.035
response to growth factor GO:0070848 198 0.035
Worm
nucleoside triphosphate catabolic process GO:0009143 205 0.035
negative regulation of intracellular signal transduction GO:1902532 167 0.034
protein ubiquitination GO:0016567 171 0.034
canonical wnt signaling pathway GO:0060070 130 0.034
protein modification by small protein conjugation or removal GO:0070647 207 0.034
lung development GO:0030324 164 0.034
organic hydroxy compound metabolic process GO:1901615 203 0.034
negative regulation of phosphate metabolic process GO:0045936 184 0.033
cellular chemical homeostasis GO:0055082 215 0.033
purine ribonucleoside catabolic process GO:0046130 205 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.033
Worm
regulation of map kinase activity GO:0043405 120 0.033
negative regulation of protein modification process GO:0031400 163 0.033
skeletal muscle cell differentiation GO:0035914 66 0.033
epithelial tube morphogenesis GO:0060562 303 0.033
regulation of cellular component biogenesis GO:0044087 181 0.033
negative regulation of fat cell differentiation GO:0045599 36 0.032
protein maturation GO:0051604 176 0.032
positive regulation of epithelial cell proliferation GO:0050679 68 0.032
guanosine containing compound metabolic process GO:1901068 144 0.032
regulation of muscle tissue development GO:1901861 97 0.032
positive regulation of protein kinase activity GO:0045860 144 0.032
protein catabolic process GO:0030163 221 0.032
regulation of response to wounding GO:1903034 189 0.032
multi multicellular organism process GO:0044706 109 0.031
guanosine containing compound catabolic process GO:1901069 144 0.031
muscle cell differentiation GO:0042692 261 0.031
negative regulation of phosphorus metabolic process GO:0010563 184 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.031
regulation of ras protein signal transduction GO:0046578 114 0.031
positive regulation of apoptotic process GO:0043065 217 0.031
Human
embryonic epithelial tube formation GO:0001838 130 0.031
regulation of leukocyte differentiation GO:1902105 159 0.031
negative regulation of proteolysis GO:0045861 74 0.031
negative regulation of cellular amine metabolic process GO:0033239 1 0.031
carbohydrate metabolic process GO:0005975 230 0.031
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.030
cellular response to molecule of bacterial origin GO:0071219 83 0.030
digestive system development GO:0055123 200 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.030
myeloid leukocyte differentiation GO:0002573 119 0.029
stem cell differentiation GO:0048863 268 0.029
cellular response to biotic stimulus GO:0071216 92 0.029
skeletal system development GO:0001501 356 0.029
Mouse
immune effector process GO:0002252 321 0.029
negative regulation of response to wounding GO:1903035 77 0.029
microtubule based process GO:0007017 236 0.029
connective tissue development GO:0061448 179 0.029
Mouse
lateral inhibition GO:0046331 1 0.028
regulation of anatomical structure size GO:0090066 178 0.028
regulation of cellular response to stress GO:0080135 159 0.028
endocytosis GO:0006897 168 0.028
protein processing GO:0016485 163 0.028
t cell differentiation in thymus GO:0033077 77 0.028
g protein coupled receptor signaling pathway GO:0007186 243 0.028
stem cell maintenance GO:0019827 130 0.028
regulation of cell migration GO:0030334 219 0.028
regulation of hormone levels GO:0010817 211 0.028
regulation of neuron projection development GO:0010975 169 0.027
modification dependent macromolecule catabolic process GO:0043632 133 0.027
digestive tract development GO:0048565 190 0.027
positive regulation of hydrolase activity GO:0051345 148 0.027
regulation of cell adhesion GO:0030155 154 0.027
membrane organization GO:0061024 245 0.027
response to peptide GO:1901652 136 0.027
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.027
oxidation reduction process GO:0055114 342 0.026
regulation of nucleoside metabolic process GO:0009118 130 0.026
positive regulation of nucleotide metabolic process GO:0045981 114 0.026
compound eye development GO:0048749 1 0.026
regulation of purine nucleotide catabolic process GO:0033121 122 0.026
regulation of cell activation GO:0050865 289 0.026
male gamete generation GO:0048232 285 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
circulatory system process GO:0003013 197 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.026
regulation of binding GO:0051098 111 0.026
spermatogenesis GO:0007283 284 0.026
telencephalon development GO:0021537 186 0.026
morphogenesis of a branching structure GO:0001763 203 0.026
protein localization to organelle GO:0033365 185 0.026
extrinsic apoptotic signaling pathway GO:0097191 126 0.026
regulation of cytoskeleton organization GO:0051493 122 0.026
response to organic cyclic compound GO:0014070 198 0.025
cellular calcium ion homeostasis GO:0006874 119 0.025
nucleocytoplasmic transport GO:0006913 139 0.025
camera type eye development GO:0043010 266 0.025
positive regulation of transferase activity GO:0051347 167 0.025
regulation of proteolysis GO:0030162 164 0.025
cellular protein catabolic process GO:0044257 155 0.025
t cell differentiation GO:0030217 174 0.025
regulation of protein localization GO:0032880 231 0.025
Mouse
cognition GO:0050890 149 0.025
negative regulation of immune system process GO:0002683 209 0.025
regulation of ovulation GO:0060278 3 0.025
central nervous system neuron differentiation GO:0021953 162 0.025
circadian regulation of gene expression GO:0032922 48 0.025
lipid biosynthetic process GO:0008610 179 0.025
regulation of interleukin 8 production GO:0032677 3 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
cellular carbohydrate metabolic process GO:0044262 119 0.024
regulation of protein serine threonine kinase activity GO:0071900 157 0.024
myotube differentiation GO:0014902 105 0.024
skin development GO:0043588 220 0.024
regulation of ossification GO:0030278 112 0.024
negative regulation of defense response GO:0031348 77 0.024
multicellular organismal signaling GO:0035637 91 0.024
hormone secretion GO:0046879 128 0.024
response to extracellular stimulus GO:0009991 127 0.024
Fly
maintenance of location GO:0051235 89 0.024
regulation of cell projection organization GO:0031344 206 0.024
regulation of gtp catabolic process GO:0033124 113 0.024
intracellular protein transport GO:0006886 204 0.024
metal ion homeostasis GO:0055065 189 0.024
cellular response to lipid GO:0071396 145 0.024
reactive oxygen species metabolic process GO:0072593 84 0.024
embryonic placenta development GO:0001892 98 0.024
cellular response to cytokine stimulus GO:0071345 189 0.024
cation homeostasis GO:0055080 212 0.024
positive regulation of gtpase activity GO:0043547 85 0.024
negative regulation of transferase activity GO:0051348 85 0.023
developmental growth involved in morphogenesis GO:0060560 138 0.023
regulation of wnt signaling pathway GO:0030111 123 0.023
response to inorganic substance GO:0010035 96 0.023
regulation of endopeptidase activity GO:0052548 89 0.023
regulation of neuron death GO:1901214 134 0.023
pallium development GO:0021543 120 0.023
endomembrane system organization GO:0010256 147 0.023
neural tube development GO:0021915 160 0.023
negative regulation of hydrolase activity GO:0051346 71 0.023
single organismal cell cell adhesion GO:0016337 131 0.023
osteoclast differentiation GO:0030316 62 0.023
heart morphogenesis GO:0003007 178 0.023
embryonic organ morphogenesis GO:0048562 276 0.023
cell fate commitment GO:0045165 210 0.023
negative regulation of neuron apoptotic process GO:0043524 92 0.023
appendage morphogenesis GO:0035107 149 0.023
Mouse
actin filament organization GO:0007015 113 0.023
negative regulation of myeloid cell differentiation GO:0045638 38 0.023
ear development GO:0043583 200 0.023
positive regulation of cytokine production GO:0001819 174 0.022
tube formation GO:0035148 140 0.022
cellular response to oxidative stress GO:0034599 76 0.022
regulation of protein maturation GO:1903317 96 0.022
respiratory gaseous exchange GO:0007585 43 0.022
jnk cascade GO:0007254 72 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.022
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.022
protein targeting GO:0006605 143 0.022
response to insulin GO:0032868 100 0.022
Mouse
cellular response to extracellular stimulus GO:0031668 81 0.022
divalent inorganic cation transport GO:0072511 178 0.022
glucose homeostasis GO:0042593 128 0.022
neuron death GO:0070997 154 0.022
establishment of protein localization to organelle GO:0072594 118 0.022
regulation of multi organism process GO:0043900 111 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
cellular ion homeostasis GO:0006873 165 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
glial cell differentiation GO:0010001 131 0.022
morphogenesis of embryonic epithelium GO:0016331 159 0.022
positive regulation of ras gtpase activity GO:0032320 65 0.022
positive regulation of neuron differentiation GO:0045666 141 0.021
cardiac muscle tissue development GO:0048738 130 0.021
epidermis development GO:0008544 187 0.021
negative regulation of kinase activity GO:0033673 81 0.021
actin cytoskeleton organization GO:0030036 220 0.021
regulation of protein transport GO:0051223 163 0.021
regulation of peptidase activity GO:0052547 96 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
response to oxygen levels GO:0070482 62 0.021
muscle cell development GO:0055001 133 0.021
positive regulation of nucleotide catabolic process GO:0030813 88 0.021
sensory organ morphogenesis GO:0090596 242 0.021
positive regulation of kinase activity GO:0033674 155 0.021
positive regulation of cell activation GO:0050867 158 0.021
lipid transport GO:0006869 98 0.021
learning or memory GO:0007611 148 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.021
regulation of body fluid levels GO:0050878 162 0.021
positive regulation of nucleoside metabolic process GO:0045979 91 0.020
neural tube formation GO:0001841 108 0.020
cellular divalent inorganic cation homeostasis GO:0072503 127 0.020
brown fat cell differentiation GO:0050873 36 0.020
regulation of ras gtpase activity GO:0032318 88 0.020
carboxylic acid biosynthetic process GO:0046394 86 0.020
locomotory behavior GO:0007626 195 0.020
protein localization to nucleus GO:0034504 121 0.020
ubiquitin dependent protein catabolic process GO:0006511 129 0.020
positive regulation of gtp catabolic process GO:0033126 85 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
stem cell proliferation GO:0072089 117 0.020
inner ear morphogenesis GO:0042472 101 0.020
regulation of canonical wnt signaling pathway GO:0060828 82 0.020
organic acid transport GO:0015849 101 0.020
bmp signaling pathway GO:0030509 93 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
activation of immune response GO:0002253 138 0.020
regulation of stress activated mapk cascade GO:0032872 69 0.020
sequestering of metal ion GO:0051238 19 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
mitotic cell cycle GO:0000278 195 0.019
epithelial cell development GO:0002064 159 0.019
cellular response to lipopolysaccharide GO:0071222 77 0.019
cell growth GO:0016049 130 0.019
nuclear division GO:0000280 158 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
Mouse
interleukin 8 production GO:0032637 4 0.019
regulation of membrane potential GO:0042391 192 0.019
regulation of neuron apoptotic process GO:0043523 122 0.019
mitotic cell cycle process GO:1903047 159 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
organ growth GO:0035265 117 0.019
negative regulation of cell motility GO:2000146 61 0.019
peptide transport GO:0015833 133 0.019
lymphocyte proliferation GO:0046651 164 0.019
stress activated protein kinase signaling cascade GO:0031098 81 0.019
germ cell development GO:0007281 185 0.019
nuclear transport GO:0051169 139 0.019
brain segmentation GO:0035284 3 0.019
epithelial tube formation GO:0072175 130 0.019
limb development GO:0060173 166 0.019
Mouse
regulation of neurotransmitter levels GO:0001505 87 0.019
developmental maturation GO:0021700 193 0.019
amide transport GO:0042886 138 0.019
regulation of vesicle mediated transport GO:0060627 139 0.019
response to acid chemical GO:0001101 111 0.018
rna processing GO:0006396 105 0.018
chromatin organization GO:0006325 206 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
digestive tract morphogenesis GO:0048546 147 0.018
cell substrate adhesion GO:0031589 130 0.018
meiotic nuclear division GO:0007126 115 0.018
neurotransmitter transport GO:0006836 76 0.018
regulation of cell size GO:0008361 72 0.018
organelle fission GO:0048285 170 0.018
lipid localization GO:0010876 126 0.018
transmission of nerve impulse GO:0019226 76 0.018
innate immune response GO:0045087 157 0.018
morphogenesis of a branching epithelium GO:0061138 193 0.018
steroid metabolic process GO:0008202 119 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
dendrite development GO:0016358 115 0.018
tube closure GO:0060606 91 0.018
gene silencing GO:0016458 38 0.018
anatomical structure homeostasis GO:0060249 145 0.018
heart growth GO:0060419 45 0.018
cellular protein complex assembly GO:0043623 116 0.018
regulation of myotube differentiation GO:0010830 62 0.018
calcium ion homeostasis GO:0055074 127 0.018
positive regulation of lymphocyte activation GO:0051251 140 0.018
blastocyst development GO:0001824 80 0.017
divalent metal ion transport GO:0070838 172 0.017
negative regulation of wnt signaling pathway GO:0030178 73 0.017
homeostasis of number of cells GO:0048872 210 0.017
regulation of actin filament based process GO:0032970 99 0.017
asymmetric stem cell division GO:0098722 3 0.017
protein import GO:0017038 101 0.017
multicellular organism growth GO:0035264 161 0.017
Mouse Worm
tissue homeostasis GO:0001894 115 0.017
negative regulation of cell migration GO:0030336 59 0.017
neuron apoptotic process GO:0051402 142 0.017
organelle localization GO:0051640 179 0.017
carboxylic acid transport GO:0046942 100 0.017
primary neural tube formation GO:0014020 95 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
limb morphogenesis GO:0035108 149 0.017
Mouse
regulation of muscle system process GO:0090257 80 0.017
insulin secretion GO:0030073 89 0.017
t cell proliferation GO:0042098 120 0.017
cardiac muscle cell differentiation GO:0055007 69 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
response to nutrient levels GO:0031667 109 0.017
Fly
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.016
peptide secretion GO:0002790 114 0.016
regulation of actin cytoskeleton organization GO:0032956 84 0.016
regulation of homeostatic process GO:0032844 182 0.016
organic hydroxy compound transport GO:0015850 93 0.016
cell matrix adhesion GO:0007160 68 0.016
negative regulation of nervous system development GO:0051961 156 0.016
smooth muscle contraction GO:0006939 44 0.016
axon guidance GO:0007411 141 0.016
regulation of organ morphogenesis GO:2000027 144 0.016
negative regulation of protein processing GO:0010955 79 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
embryonic appendage morphogenesis GO:0035113 126 0.016
regulation of cellular response to growth factor stimulus GO:0090287 82 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
glycoprotein metabolic process GO:0009100 116 0.016
midgut development GO:0007494 4 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
cell junction organization GO:0034330 77 0.016
positive regulation of secretion GO:0051047 130 0.016
embryonic limb morphogenesis GO:0030326 126 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
muscle contraction GO:0006936 101 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
extracellular structure organization GO:0043062 148 0.016
ear morphogenesis GO:0042471 118 0.016
cell maturation GO:0048469 127 0.016
regulation of peptide secretion GO:0002791 77 0.016
neural tube closure GO:0001843 90 0.016
positive regulation of cell cycle GO:0045787 92 0.016
hindbrain development GO:0030902 128 0.016
tissue remodeling GO:0048771 102 0.016
chemotaxis GO:0006935 247 0.015
negative regulation of growth GO:0045926 99 0.015
establishment of organelle localization GO:0051656 122 0.015
biomineral tissue development GO:0031214 64 0.015
regulation of ion transport GO:0043269 215 0.015
Rat
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.015
sensory perception GO:0007600 245 0.015
Worm
neuron migration GO:0001764 122 0.015
regulation of protein processing GO:0070613 96 0.015
peptide hormone secretion GO:0030072 109 0.015
negative regulation of protein maturation GO:1903318 79 0.015
rhythmic process GO:0048511 174 0.015
myeloid leukocyte activation GO:0002274 83 0.015
meiotic cell cycle GO:0051321 122 0.015
response to hypoxia GO:0001666 58 0.015
hepaticobiliary system development GO:0061008 67 0.015
chromatin modification GO:0016568 187 0.015
myosin filament organization GO:0031033 3 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
positive regulation of cell projection organization GO:0031346 95 0.015
organic acid biosynthetic process GO:0016053 86 0.015
negative regulation of neuron death GO:1901215 98 0.015
regulation of cell cycle process GO:0010564 160 0.015
branching morphogenesis of an epithelial tube GO:0048754 159 0.015
kidney epithelium development GO:0072073 121 0.015
pharynx development GO:0060465 1 0.015
translation GO:0006412 93 0.015
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
leukocyte mediated immunity GO:0002443 174 0.015
sequestering of calcium ion GO:0051208 18 0.015
liver development GO:0001889 66 0.015
regulation of cysteine type endopeptidase activity GO:2000116 65 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
skeletal system morphogenesis GO:0048705 203 0.015
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.015

Sik1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.031
disease of anatomical entity DOID:7 0 0.031
disease of metabolism DOID:0014667 0 0.024
musculoskeletal system disease DOID:17 0 0.021
bone disease DOID:0080001 0 0.021
connective tissue disease DOID:65 0 0.021
central nervous system disease DOID:331 0 0.015