Mus musculus

0 known processes

Mthfd1l

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

(Aliases: 2410004L15Rik,AI647056,Fthfsdc1)

Mthfd1l biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.108
Human Yeast
ion transmembrane transport GO:0034220 361 0.085
transmembrane transport GO:0055085 412 0.078
nitrogen compound transport GO:0071705 271 0.071
nucleobase containing small molecule metabolic process GO:0055086 352 0.060
Yeast
anion transport GO:0006820 177 0.060
cation transport GO:0006812 399 0.058
cellular ketone metabolic process GO:0042180 84 0.052
amine metabolic process GO:0009308 45 0.050
ribonucleotide metabolic process GO:0009259 291 0.047
cellular amine metabolic process GO:0044106 44 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.042
nucleoside triphosphate metabolic process GO:0009141 230 0.041
organelle fission GO:0048285 170 0.041
organonitrogen compound biosynthetic process GO:1901566 192 0.040
Yeast
organic anion transport GO:0015711 137 0.039
regulation of cell cycle GO:0051726 281 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.037
oxidation reduction process GO:0055114 342 0.037
Yeast
regulation of cellular ketone metabolic process GO:0010565 66 0.037
purine containing compound metabolic process GO:0072521 311 0.037
Yeast
nucleoside metabolic process GO:0009116 246 0.036
ribose phosphate metabolic process GO:0019693 291 0.036
cellular response to dna damage stimulus GO:0006974 207 0.036
purine nucleotide metabolic process GO:0006163 302 0.035
dna metabolic process GO:0006259 303 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
carbohydrate derivative biosynthetic process GO:1901137 183 0.033
purine ribonucleoside metabolic process GO:0046128 241 0.033
regulation of cellular catabolic process GO:0031329 242 0.033
anion transmembrane transport GO:0098656 71 0.032
apoptotic signaling pathway GO:0097190 306 0.032
response to organonitrogen compound GO:0010243 246 0.032
dna repair GO:0006281 107 0.031
heterocycle catabolic process GO:0046700 280 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
carboxylic acid transport GO:0046942 100 0.031
membrane organization GO:0061024 245 0.029
purine nucleoside triphosphate metabolic process GO:0009144 226 0.028
amino acid transmembrane transport GO:0003333 37 0.028
negative regulation of cell proliferation GO:0008285 296 0.028
cytoplasmic transport GO:0016482 234 0.028
purine nucleoside metabolic process GO:0042278 241 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
chromatin organization GO:0006325 206 0.027
nucleotide metabolic process GO:0009117 332 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
cellular homeostasis GO:0019725 240 0.026
aromatic compound catabolic process GO:0019439 286 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
purine containing compound catabolic process GO:0072523 213 0.026
regulation of mitotic cell cycle GO:0007346 126 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
regulation of cell activation GO:0050865 289 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
cation transmembrane transport GO:0098655 266 0.025
peptidyl amino acid modification GO:0018193 336 0.025
nucleoside catabolic process GO:0009164 206 0.025
ribonucleotide catabolic process GO:0009261 208 0.025
ribonucleoside metabolic process GO:0009119 245 0.024
organophosphate biosynthetic process GO:0090407 122 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
response to organic cyclic compound GO:0014070 198 0.024
cellular lipid metabolic process GO:0044255 323 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
organic acid transport GO:0015849 101 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.023
sulfur compound metabolic process GO:0006790 100 0.023
positive regulation of cell death GO:0010942 224 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
dna endoreduplication GO:0042023 4 0.023
carbohydrate metabolic process GO:0005975 230 0.023
positive regulation of programmed cell death GO:0043068 218 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
regulation of hydrolase activity GO:0051336 246 0.022
lipid biosynthetic process GO:0008610 179 0.022
alpha amino acid metabolic process GO:1901605 59 0.022
Human Yeast
cofactor metabolic process GO:0051186 80 0.022
Human Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
camera type eye development GO:0043010 266 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
l amino acid transport GO:0015807 32 0.022
nucleotide catabolic process GO:0009166 217 0.022
mitotic cell cycle GO:0000278 195 0.021
lymphocyte proliferation GO:0046651 164 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
nuclear division GO:0000280 158 0.021
organic acid biosynthetic process GO:0016053 86 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
microtubule based process GO:0007017 236 0.021
organophosphate catabolic process GO:0046434 232 0.020
negative regulation of chromatin silencing GO:0031936 1 0.020
endocytosis GO:0006897 168 0.020
negative regulation of molecular function GO:0044092 258 0.020
inflammatory response GO:0006954 244 0.020
cellular response to cytokine stimulus GO:0071345 189 0.020
regulation of intracellular transport GO:0032386 159 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
cellular chemical homeostasis GO:0055082 215 0.020
cell adhesion GO:0007155 329 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
nuclear transport GO:0051169 139 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
regulation of defense response GO:0031347 233 0.019
double strand break repair GO:0006302 48 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
divalent metal ion transport GO:0070838 172 0.019
male gamete generation GO:0048232 285 0.019
small molecule biosynthetic process GO:0044283 132 0.019
leukocyte proliferation GO:0070661 172 0.019
cell type specific apoptotic process GO:0097285 268 0.019
response to inorganic substance GO:0010035 96 0.018
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
amino acid transport GO:0006865 61 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
regulation of secretion by cell GO:1903530 249 0.018
cellular modified amino acid metabolic process GO:0006575 63 0.018
Human Yeast
mitotic cell cycle process GO:1903047 159 0.018
spermatogenesis GO:0007283 284 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
response to nutrient levels GO:0031667 109 0.018
response to acid chemical GO:0001101 111 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
regulation of hormone levels GO:0010817 211 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
regulation of organelle organization GO:0033043 289 0.018
regulation of cell cycle process GO:0010564 160 0.018
blood circulation GO:0008015 195 0.017
t cell activation GO:0042110 289 0.017
cation homeostasis GO:0055080 212 0.017
immune effector process GO:0002252 321 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
regulation of ion transport GO:0043269 215 0.017
l alpha amino acid transmembrane transport GO:1902475 23 0.017
folic acid containing compound metabolic process GO:0006760 3 0.017
Human Yeast
regulation of cellular response to stress GO:0080135 159 0.017
sequestering of calcium ion GO:0051208 18 0.017
regulation of cell migration GO:0030334 219 0.017
macromolecule catabolic process GO:0009057 281 0.017
response to extracellular stimulus GO:0009991 127 0.016
circulatory system process GO:0003013 197 0.016
regulation of circadian sleep wake cycle GO:0042749 3 0.016
skeletal system development GO:0001501 356 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
protein maturation GO:0051604 176 0.016
locomotory behavior GO:0007626 195 0.016
positive regulation of cell activation GO:0050867 158 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
regulation of membrane potential GO:0042391 192 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
regulation of cell motility GO:2000145 236 0.016
gland development GO:0048732 330 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
Human
regulation of secretion GO:0051046 274 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
muscle cell differentiation GO:0042692 261 0.016
intracellular protein transport GO:0006886 204 0.016
leukocyte differentiation GO:0002521 342 0.016
alcohol metabolic process GO:0006066 116 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
sensory perception GO:0007600 245 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
negative regulation of protein modification process GO:0031400 163 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
neuron death GO:0070997 154 0.015
methionine transport GO:0015821 1 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
regulation of protein localization GO:0032880 231 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
hexose metabolic process GO:0019318 98 0.015
germ cell development GO:0007281 185 0.015
actin cytoskeleton organization GO:0030036 220 0.015
metal ion homeostasis GO:0055065 189 0.015
homeostasis of number of cells GO:0048872 210 0.015
nuclear dna replication GO:0033260 3 0.015
forebrain development GO:0030900 302 0.015
dna recombination GO:0006310 92 0.015
b cell activation GO:0042113 161 0.015
maintenance of location GO:0051235 89 0.015
coenzyme metabolic process GO:0006732 52 0.015
Human Yeast
innate immune response GO:0045087 157 0.015
mapk cascade GO:0000165 281 0.014
mitochondrion organization GO:0007005 134 0.014
positive regulation of cell development GO:0010720 237 0.014
response to oxidative stress GO:0006979 123 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
protein processing GO:0016485 163 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
monosaccharide metabolic process GO:0005996 106 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
striated muscle myosin thick filament assembly GO:0071688 1 0.014
anatomical structure homeostasis GO:0060249 145 0.014
regulation of homeostatic process GO:0032844 182 0.014
cell substrate adhesion GO:0031589 130 0.014
cellular ion homeostasis GO:0006873 165 0.014
blood vessel morphogenesis GO:0048514 285 0.014
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
glucose homeostasis GO:0042593 128 0.013
lateral inhibition GO:0046331 1 0.013
regulation of protein kinase activity GO:0045859 232 0.013
myosin filament assembly GO:0031034 2 0.013
meiotic cell cycle GO:0051321 122 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
development of primary sexual characteristics GO:0045137 143 0.013
meiotic nuclear division GO:0007126 115 0.013
divalent inorganic cation transport GO:0072511 178 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
gonad development GO:0008406 141 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
nucleobase containing compound transport GO:0015931 27 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
chemotaxis GO:0006935 247 0.013
ras protein signal transduction GO:0007265 77 0.013
myeloid cell differentiation GO:0030099 233 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
tissue homeostasis GO:0001894 115 0.013
dna replication GO:0006260 52 0.013
respiratory system development GO:0060541 190 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
sequestering of metal ion GO:0051238 19 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
axonogenesis GO:0007409 274 0.012
leukocyte mediated immunity GO:0002443 174 0.012
neuron apoptotic process GO:0051402 142 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
protein localization to organelle GO:0033365 185 0.012
defense response to other organism GO:0098542 197 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
ossification GO:0001503 216 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
gtp metabolic process GO:0046039 144 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
dna dependent dna replication GO:0006261 24 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
response to lipopolysaccharide GO:0032496 128 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
cellular protein complex assembly GO:0043623 116 0.012
cellular response to acid chemical GO:0071229 68 0.012
response to light stimulus GO:0009416 135 0.012
regulation of transferase activity GO:0051338 263 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
regulation of cell adhesion GO:0030155 154 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
cellular response to lipid GO:0071396 145 0.012
regulation of response to wounding GO:1903034 189 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
protein targeting GO:0006605 143 0.011
response to growth factor GO:0070848 198 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
branched chain amino acid transport GO:0015803 2 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
cell growth GO:0016049 130 0.011
recombinational repair GO:0000725 21 0.011
mrna transport GO:0051028 13 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
rhythmic process GO:0048511 174 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
receptor mediated endocytosis GO:0006898 51 0.011
cell cycle g1 s phase transition GO:0044843 57 0.011
urogenital system development GO:0001655 261 0.011
regulation of system process GO:0044057 200 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
nuclear export GO:0051168 34 0.011
cell activation involved in immune response GO:0002263 126 0.011
calcium ion homeostasis GO:0055074 127 0.011
amide transport GO:0042886 138 0.011
regulation of inflammatory response GO:0050727 147 0.011
steroid metabolic process GO:0008202 119 0.011
regulation of cell division GO:0051302 76 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
macromolecule methylation GO:0043414 120 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
cognition GO:0050890 149 0.011
regulation of kinase activity GO:0043549 249 0.011
cellular amide metabolic process GO:0043603 58 0.011
positive regulation of protein modification process GO:0031401 299 0.011
response to radiation GO:0009314 165 0.011
chromatin modification GO:0016568 187 0.011
meiotic cell cycle process GO:1903046 77 0.011
regulation of neuron differentiation GO:0045664 281 0.011
t cell proliferation GO:0042098 120 0.011
atp metabolic process GO:0046034 75 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
calcium ion transport GO:0006816 159 0.011
lymphocyte differentiation GO:0030098 242 0.011
regulation of anatomical structure size GO:0090066 178 0.011
leukocyte migration GO:0050900 124 0.011
adult behavior GO:0030534 135 0.011
glial cell differentiation GO:0010001 131 0.010
methylation GO:0032259 134 0.010
carbohydrate homeostasis GO:0033500 128 0.010
positive regulation of immune effector process GO:0002699 107 0.010
hormone secretion GO:0046879 128 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
adaptive immune response GO:0002250 155 0.010
action potential GO:0001508 78 0.010
fatty acid metabolic process GO:0006631 121 0.010
cellular response to external stimulus GO:0071496 88 0.010
gliogenesis GO:0042063 141 0.010
single organism cell adhesion GO:0098602 156 0.010
circadian rhythm GO:0007623 114 0.010
gtp catabolic process GO:0006184 143 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
protein ubiquitination GO:0016567 171 0.010
activation of immune response GO:0002253 138 0.010
protein localization to nucleus GO:0034504 121 0.010
cell division GO:0051301 120 0.010
response to metal ion GO:0010038 47 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
response to amino acid GO:0043200 37 0.010
negative regulation of cell cycle GO:0045786 123 0.010
regulation of neuron death GO:1901214 134 0.010
regulation of transmembrane transport GO:0034762 128 0.010
gene silencing GO:0016458 38 0.010
response to peptide GO:1901652 136 0.010
regulation of cytokine production GO:0001817 266 0.010

Mthfd1l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.036
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
inherited metabolic disorder DOID:655 0 0.028
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
gastrointestinal system cancer DOID:3119 0 0.014
intestinal cancer DOID:10155 0 0.014
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012
neuropathy DOID:870 0 0.010
neuromuscular disease DOID:440 0 0.010