Mus musculus

72 known processes

Trim59

tripartite motif-containing 59

(Aliases: 2310035M22Rik,2700022F13Rik,Mrf1,TSBF1)

Trim59 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiosis i GO:0007127 60 0.929
meiotic cell cycle GO:0051321 122 0.843
microtubule polymerization or depolymerization GO:0031109 26 0.733
Mouse
meiotic cell cycle process GO:1903046 77 0.727
microtubule based process GO:0007017 236 0.644
Mouse
organelle fission GO:0048285 170 0.617
female meiotic division GO:0007143 21 0.594
spindle assembly involved in meiosis GO:0090306 4 0.551
establishment of organelle localization GO:0051656 122 0.526
chromosome segregation GO:0007059 48 0.493
mitotic cell cycle process GO:1903047 159 0.424
organelle assembly GO:0070925 177 0.408
meiotic nuclear division GO:0007126 115 0.393
positive regulation of cell division GO:0051781 31 0.382
chromosome organization involved in meiosis GO:0070192 39 0.376
mitotic sister chromatid segregation GO:0000070 14 0.363
microtubule cytoskeleton organization GO:0000226 157 0.360
Mouse
negative regulation of cellular component organization GO:0051129 194 0.321
Mouse
spindle assembly involved in female meiosis GO:0007056 3 0.315
spindle assembly involved in female meiosis i GO:0007057 2 0.307
organelle localization GO:0051640 179 0.292
male gamete generation GO:0048232 285 0.281
spindle assembly involved in mitosis GO:0090307 4 0.276
dna metabolic process GO:0006259 303 0.275
regulation of microtubule based process GO:0032886 52 0.273
Mouse
mitotic cytokinesis GO:0000281 4 0.266
regulation of centriole replication GO:0046599 1 0.264
negative regulation of cell cycle GO:0045786 123 0.259
regulation of cell cycle process GO:0010564 160 0.245
meiotic chromosome segregation GO:0045132 19 0.238
regulation of mitosis GO:0007088 29 0.238
kinetochore organization GO:0051383 2 0.236
negative regulation of nuclear division GO:0051784 19 0.221
nuclear division GO:0000280 158 0.209
regulation of cell division GO:0051302 76 0.190
mitotic cell cycle GO:0000278 195 0.185
microtubule organizing center organization GO:0031023 28 0.180
cellular amine metabolic process GO:0044106 44 0.176
regulation of organelle organization GO:0033043 289 0.175
Mouse
mitotic chromosome condensation GO:0007076 1 0.163
development of primary sexual characteristics GO:0045137 143 0.156
regulation of chromosome organization GO:0033044 83 0.150
spermatogenesis GO:0007283 284 0.140
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.139
female meiosis i GO:0007144 7 0.138
cell division GO:0051301 120 0.133
chromatin remodeling at centromere GO:0031055 2 0.131
regulation of cytoskeleton organization GO:0051493 122 0.131
Mouse
attachment of spindle microtubules to kinetochore GO:0008608 4 0.125
regulation of cell cycle GO:0051726 281 0.124
sister chromatid segregation GO:0000819 20 0.122
cellular protein complex disassembly GO:0043624 36 0.118
Mouse
spindle assembly GO:0051225 13 0.117
spindle checkpoint GO:0031577 12 0.116
mitotic nuclear division GO:0007067 48 0.111
regulation of meiosis i GO:0060631 7 0.104
regulation of nuclear division GO:0051783 56 0.101
negative regulation of meiotic cell cycle GO:0051447 14 0.098
regulation of mitotic cell cycle GO:0007346 126 0.098
negative regulation of organelle organization GO:0010639 90 0.096
Mouse
germ cell development GO:0007281 185 0.094
spermatid development GO:0007286 108 0.093
cellular ketone metabolic process GO:0042180 84 0.091
regulation of cellular amino acid metabolic process GO:0006521 5 0.091
centromere complex assembly GO:0034508 3 0.091
negative regulation of cellular protein metabolic process GO:0032269 247 0.090
regulation of protein complex disassembly GO:0043244 28 0.087
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.085
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.085
synapsis GO:0007129 34 0.085
protein complex disassembly GO:0043241 40 0.084
Mouse
negative regulation of cell division GO:0051782 24 0.082
amine metabolic process GO:0009308 45 0.080
cytokinetic process GO:0032506 2 0.080
spermatid differentiation GO:0048515 115 0.080
gonad development GO:0008406 141 0.080
macromolecule catabolic process GO:0009057 281 0.078
Mouse
male meiosis GO:0007140 37 0.075
gene silencing GO:0016458 38 0.069
cellular protein complex assembly GO:0043623 116 0.066
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.064
Mouse
positive regulation of nfat protein import into nucleus GO:0051533 1 0.063
fertilization GO:0009566 127 0.063
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.061
meiotic spindle organization GO:0000212 9 0.061
microtubule nucleation GO:0007020 2 0.060
positive regulation of meiosis i GO:0060903 5 0.058
cellular macromolecule catabolic process GO:0044265 206 0.056
Mouse
regulation of cell projection organization GO:0031344 206 0.055
regulation of protein maturation GO:1903317 96 0.052
regulation of cellular catabolic process GO:0031329 242 0.052
protein modification by small protein conjugation or removal GO:0070647 207 0.052
positive regulation of cellular amine metabolic process GO:0033240 5 0.052
meiotic cytokinesis GO:0033206 5 0.052
negative regulation of cell cycle process GO:0010948 69 0.050
regulation of cellular protein catabolic process GO:1903362 61 0.050
regulation of transferase activity GO:0051338 263 0.049
cytokinesis GO:0000910 17 0.049
neuron migration GO:0001764 122 0.049
cellular amino acid metabolic process GO:0006520 103 0.049
protein maturation GO:0051604 176 0.048
protein localization to organelle GO:0033365 185 0.048
regulation of cytokinesis GO:0032465 5 0.046
regulation of cell cycle phase transition GO:1901987 77 0.046
cell cycle checkpoint GO:0000075 47 0.046
regulation of apoptotic signaling pathway GO:2001233 197 0.045
centrosome organization GO:0051297 26 0.045
spindle organization GO:0007051 28 0.044
negative regulation of chromosome organization GO:2001251 30 0.044
regulation of neuron differentiation GO:0045664 281 0.044
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.042
Mouse
dendrite development GO:0016358 115 0.042
female meiosis chromosome segregation GO:0016321 1 0.042
positive regulation of cell cycle process GO:0090068 61 0.042
apoptotic signaling pathway GO:0097190 306 0.042
positive regulation of protein modification process GO:0031401 299 0.042
positive regulation of apoptotic process GO:0043065 217 0.041
regulation of mitotic cell cycle phase transition GO:1901990 73 0.041
modification dependent protein catabolic process GO:0019941 133 0.041
Mouse
nucleocytoplasmic transport GO:0006913 139 0.041
nuclear transport GO:0051169 139 0.040
intracellular protein transport GO:0006886 204 0.040
negative regulation of mitotic cell cycle GO:0045930 58 0.040
protein catabolic process GO:0030163 221 0.040
Mouse
positive regulation of intracellular transport GO:0032388 70 0.039
ribonucleoside triphosphate metabolic process GO:0009199 220 0.039
negative regulation of cellular protein catabolic process GO:1903363 22 0.039
nucleus localization GO:0051647 20 0.038
wnt signaling pathway GO:0016055 188 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.037
nucleotide metabolic process GO:0009117 332 0.037
peptidyl amino acid modification GO:0018193 336 0.037
cdc42 protein signal transduction GO:0032488 0 0.036
hematopoietic progenitor cell differentiation GO:0002244 143 0.036
single fertilization GO:0007338 82 0.036
female gamete generation GO:0007292 74 0.035
oocyte maturation GO:0001556 18 0.035
regulation of ras protein signal transduction GO:0046578 114 0.034
regulation of nucleocytoplasmic transport GO:0046822 73 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
regulation of protein localization GO:0032880 231 0.033
protein depolymerization GO:0051261 34 0.033
Mouse
negative regulation of proteolysis GO:0045861 74 0.033
regulation of exit from mitosis GO:0007096 1 0.032
centrosome cycle GO:0007098 23 0.032
establishment of spindle localization GO:0051293 19 0.032
intrinsic apoptotic signaling pathway GO:0097193 132 0.032
mitotic cell cycle checkpoint GO:0007093 31 0.032
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.032
positive regulation of organelle organization GO:0010638 128 0.031
meiotic chromosome condensation GO:0010032 3 0.031
regulation of protein transport GO:0051223 163 0.031
genitalia development GO:0048806 37 0.031
positive regulation of nervous system development GO:0051962 221 0.031
macromolecular complex disassembly GO:0032984 43 0.031
Mouse
regulation of intracellular transport GO:0032386 159 0.030
positive regulation of gtp catabolic process GO:0033126 85 0.030
neuroblast proliferation GO:0007405 49 0.030
dna conformation change GO:0071103 37 0.030
rho protein signal transduction GO:0007266 32 0.030
cellular response to dna damage stimulus GO:0006974 207 0.030
protein localization to nucleus GO:0034504 121 0.030
cell type specific apoptotic process GO:0097285 268 0.029
regulation of chromosome segregation GO:0051983 21 0.029
regulation of neuron projection development GO:0010975 169 0.029
cellular protein catabolic process GO:0044257 155 0.028
Mouse
regulation of intracellular protein transport GO:0033157 82 0.028
heterocycle catabolic process GO:0046700 280 0.028
regulation of protein catabolic process GO:0042176 108 0.027
meiosis ii GO:0007135 7 0.027
regulation of proteolysis GO:0030162 164 0.027
anion transport GO:0006820 177 0.027
maintenance of location GO:0051235 89 0.026
regulation of cytoplasmic transport GO:1903649 112 0.026
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.026
receptor mediated endocytosis GO:0006898 51 0.025
negative regulation of cytoskeleton organization GO:0051494 36 0.025
Mouse
digestive system development GO:0055123 200 0.025
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 8 0.025
regulation of protein kinase activity GO:0045859 232 0.024
dna ligation GO:0006266 3 0.024
double strand break repair GO:0006302 48 0.024
protein polymerization GO:0051258 57 0.024
negative regulation of sister chromatid segregation GO:0033046 7 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
positive regulation of hydrolase activity GO:0051345 148 0.024
single organism nuclear import GO:1902593 95 0.024
negative regulation of protein depolymerization GO:1901880 21 0.024
Mouse
dna packaging GO:0006323 30 0.024
protein import into nucleus GO:0006606 95 0.024
proteasomal protein catabolic process GO:0010498 98 0.024
Mouse
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.023
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.023
Mouse
regulation of ras gtpase activity GO:0032318 88 0.023
synaptonemal complex assembly GO:0007130 13 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
negative regulation of mitotic sister chromatid segregation GO:0033048 7 0.023
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.023
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.022
negative regulation of protein complex disassembly GO:0043242 22 0.022
Mouse
regulation of rho gtpase activity GO:0032319 58 0.022
regulation of cell cycle g2 m phase transition GO:1902749 10 0.022
astral microtubule organization GO:0030953 3 0.022
endocytosis GO:0006897 168 0.022
positive regulation of protein kinase activity GO:0045860 144 0.022
regulation of dna replication GO:0006275 17 0.022
positive regulation of cell cycle GO:0045787 92 0.022
actomyosin structure organization GO:0031032 56 0.021
negative regulation of microtubule depolymerization GO:0007026 13 0.021
Mouse
centrosome duplication GO:0051298 16 0.021
ras protein signal transduction GO:0007265 77 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
aromatic compound catabolic process GO:0019439 286 0.021
regulation of wnt signaling pathway GO:0030111 123 0.021
metaphase plate congression GO:0051310 2 0.021
rna interference GO:0016246 2 0.021
protein import GO:0017038 101 0.021
regulation of microtubule depolymerization GO:0031114 13 0.021
Mouse
negative regulation of molecular function GO:0044092 258 0.021
dna modification GO:0006304 50 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
mitotic spindle assembly checkpoint GO:0007094 7 0.020
positive regulation of transferase activity GO:0051347 167 0.020
response to oxidative stress GO:0006979 123 0.020
centrosome separation GO:0051299 4 0.020
chromosome separation GO:0051304 14 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
negative regulation of cellular catabolic process GO:0031330 47 0.020
dna replication GO:0006260 52 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
microtubule depolymerization GO:0007019 15 0.019
Mouse
homeostasis of number of cells GO:0048872 210 0.019
blood vessel morphogenesis GO:0048514 285 0.019
positive regulation of kinase activity GO:0033674 155 0.019
positive regulation of cell death GO:0010942 224 0.019
regulation of microtubule cytoskeleton organization GO:0070507 37 0.019
Mouse
positive regulation of mitotic cell cycle GO:0045931 41 0.019
nitrogen compound transport GO:0071705 271 0.019
dna methylation GO:0006306 43 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
placenta development GO:0001890 140 0.018
regulation of protein processing GO:0070613 96 0.018
regulation of protein import into nucleus GO:0042306 52 0.018
positive regulation of nuclear division GO:0051785 27 0.018
negative regulation of mitosis GO:0045839 10 0.018
chromatin modification GO:0016568 187 0.018
cellular lipid metabolic process GO:0044255 323 0.018
negative regulation of meiotic cell cycle phase transition GO:1901994 3 0.017
negative regulation of mitotic metaphase anaphase transition GO:0045841 7 0.017
regulation of cell activation GO:0050865 289 0.017
negative regulation of cell cycle phase transition GO:1901988 48 0.017
axonogenesis GO:0007409 274 0.017
male sex differentiation GO:0046661 109 0.016
peptidyl serine phosphorylation GO:0018105 74 0.016
dna repair GO:0006281 107 0.016
methylation GO:0032259 134 0.016
neuron apoptotic process GO:0051402 142 0.016
positive regulation of nucleoside metabolic process GO:0045979 91 0.016
cell fate commitment GO:0045165 210 0.016
leukocyte differentiation GO:0002521 342 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
establishment or maintenance of cell polarity GO:0007163 86 0.016
respiratory system development GO:0060541 190 0.016
heterochromatin organization GO:0070828 4 0.016
developmental maturation GO:0021700 193 0.016
regulation of actin filament based process GO:0032970 99 0.015
protein targeting GO:0006605 143 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
microtubule based movement GO:0007018 84 0.015
regulation of spindle organization GO:0090224 2 0.015
cellular response to metal ion GO:0071248 31 0.015
regulation of hormone levels GO:0010817 211 0.015
mrna processing GO:0006397 63 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
negative regulation of mitotic sister chromatid separation GO:2000816 7 0.015
cerebral cortex development GO:0021987 86 0.015
regulation of protein depolymerization GO:1901879 26 0.015
Mouse
regulation of kinase activity GO:0043549 249 0.015
mesodermal cell migration GO:0008078 4 0.015
regulation of mitotic metaphase anaphase transition GO:0030071 8 0.015
regulation of mitotic sister chromatid segregation GO:0033047 12 0.015
cell migration involved in gastrulation GO:0042074 13 0.015
b cell differentiation GO:0030183 78 0.014
response to decreased oxygen levels GO:0036293 59 0.014
cellular response to inorganic substance GO:0071241 37 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
Mouse
ameboidal type cell migration GO:0001667 128 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
myeloid cell differentiation GO:0030099 233 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
positive regulation of intracellular protein transport GO:0090316 42 0.014
positive regulation of glycogen catabolic process GO:0045819 2 0.014
cytoplasmic transport GO:0016482 234 0.014
deoxyribonucleotide metabolic process GO:0009262 14 0.014
positive regulation of cytoskeleton organization GO:0051495 49 0.014
protein ubiquitination GO:0016567 171 0.014
reciprocal dna recombination GO:0035825 16 0.013
mitotic cell cycle embryonic GO:0045448 5 0.013
microtubule polymerization GO:0046785 12 0.013
development of primary male sexual characteristics GO:0046546 88 0.013
negative regulation of wnt signaling pathway GO:0030178 73 0.013
gtp catabolic process GO:0006184 143 0.013
negative regulation of cell activation GO:0050866 111 0.013
negative regulation of protein processing GO:0010955 79 0.013
regulation of cellular response to hypoxia GO:1900037 2 0.013
negative regulation of protein catabolic process GO:0042177 36 0.013
positive regulation of protein transport GO:0051222 93 0.013
forebrain development GO:0030900 302 0.013
regulation of hydrolase activity GO:0051336 246 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
neural precursor cell proliferation GO:0061351 121 0.013
regulation of meiotic cell cycle GO:0051445 34 0.013
male gonad development GO:0008584 88 0.013
actin cytoskeleton organization GO:0030036 220 0.013
gastrulation GO:0007369 116 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
gtp metabolic process GO:0046039 144 0.013
meiotic dna double strand break formation GO:0042138 3 0.013
smoothened signaling pathway GO:0007224 105 0.012
cellularization GO:0007349 1 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
protein methylation GO:0006479 81 0.012
positive regulation of cell development GO:0010720 237 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
neural tube formation GO:0001841 108 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
regulation of homeostatic process GO:0032844 182 0.012
maintenance of dna methylation GO:0010216 4 0.012
telencephalon development GO:0021537 186 0.012
activation of rac gtpase activity GO:0032863 2 0.012
oxidation reduction process GO:0055114 342 0.012
muscle cell differentiation GO:0042692 261 0.012
ovulation GO:0030728 15 0.012
regulation of canonical wnt signaling pathway GO:0060828 82 0.012
microtubule sliding GO:0051012 1 0.012
rna 3 end processing GO:0031123 20 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
response to hypoxia GO:0001666 58 0.012
protein processing GO:0016485 163 0.012
negative regulation of phagocytosis GO:0050765 4 0.011
b cell activation GO:0042113 161 0.011
nucleoside catabolic process GO:0009164 206 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
response to oxygen levels GO:0070482 62 0.011
muscle tissue development GO:0060537 308 0.011
negative regulation of b cell differentiation GO:0045578 4 0.011
carbohydrate homeostasis GO:0033500 128 0.011
regulation of centrosome cycle GO:0046605 10 0.011
neuron death GO:0070997 154 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
macromolecule methylation GO:0043414 120 0.011
purine containing compound metabolic process GO:0072521 311 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
membrane organization GO:0061024 245 0.011
negative regulation of protein maturation GO:1903318 79 0.011
mitotic centrosome separation GO:0007100 4 0.011
neural tube closure GO:0001843 90 0.011
cellular response to lipid GO:0071396 145 0.011
Mouse
centriole assembly GO:0098534 6 0.011
multicellular organism growth GO:0035264 161 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
nucleus organization GO:0006997 45 0.011
negative regulation of cell development GO:0010721 169 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
nuclear import GO:0051170 95 0.011
synaptonemal complex organization GO:0070193 15 0.010
microtubule anchoring GO:0034453 9 0.010
lymphocyte differentiation GO:0030098 242 0.010
mitotic recombination GO:0006312 3 0.010
heterochromatin assembly GO:0031507 2 0.010
dna recombination GO:0006310 92 0.010
negative regulation of apoptotic cell clearance GO:2000426 1 0.010
regulation of histone modification GO:0031056 56 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
dna endoreduplication GO:0042023 4 0.010
response to organic cyclic compound GO:0014070 198 0.010
Mouse

Trim59 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.020