Mus musculus

0 known processes

Trim58

tripartite motif-containing 58

(Aliases: Gm16,Gm1783)

Trim58 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.047
amine metabolic process GO:0009308 45 0.045
cellular amine metabolic process GO:0044106 44 0.045
regulation of cytokine production GO:0001817 266 0.043
Mouse
cellular ketone metabolic process GO:0042180 84 0.041
cytokine production GO:0001816 319 0.041
Mouse
immune effector process GO:0002252 321 0.040
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
cation transport GO:0006812 399 0.036
sensory perception GO:0007600 245 0.036
regulation of defense response GO:0031347 233 0.036
Mouse
transmembrane transport GO:0055085 412 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.034
inflammatory response GO:0006954 244 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.032
nitrogen compound transport GO:0071705 271 0.030
response to molecule of bacterial origin GO:0002237 143 0.030
response to organonitrogen compound GO:0010243 246 0.029
cellular response to lipid GO:0071396 145 0.029
response to lipopolysaccharide GO:0032496 128 0.027
cation transmembrane transport GO:0098655 266 0.027
regulation of membrane potential GO:0042391 192 0.026
oxidation reduction process GO:0055114 342 0.026
neuronal action potential GO:0019228 54 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
ion transmembrane transport GO:0034220 361 0.026
cellular lipid metabolic process GO:0044255 323 0.026
reactive oxygen species metabolic process GO:0072593 84 0.025
Mouse
cellular response to biotic stimulus GO:0071216 92 0.025
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.025
cellular response to lipopolysaccharide GO:0071222 77 0.025
leukocyte differentiation GO:0002521 342 0.024
transmission of nerve impulse GO:0019226 76 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
regulation of secretion GO:0051046 274 0.024
cation homeostasis GO:0055080 212 0.024
regulation of protein localization GO:0032880 231 0.023
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
defense response to other organism GO:0098542 197 0.023
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.022
Mouse
regulation of inflammatory response GO:0050727 147 0.022
regulation of secretion by cell GO:1903530 249 0.022
multicellular organismal signaling GO:0035637 91 0.022
cellular response to molecule of bacterial origin GO:0071219 83 0.022
myeloid cell differentiation GO:0030099 233 0.021
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
negative regulation of molecular function GO:0044092 258 0.021
macromolecule catabolic process GO:0009057 281 0.021
Mouse
regulation of hormone levels GO:0010817 211 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
protein ubiquitination GO:0016567 171 0.021
Mouse
negative regulation of cell proliferation GO:0008285 296 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.020
cellular chemical homeostasis GO:0055082 215 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
regulation of cell activation GO:0050865 289 0.020
action potential GO:0001508 78 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
innate immune response GO:0045087 157 0.019
Mouse
peptidyl amino acid modification GO:0018193 336 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
blood vessel morphogenesis GO:0048514 285 0.019
regulation of response to wounding GO:1903034 189 0.019
positive regulation of protein modification process GO:0031401 299 0.019
apoptotic signaling pathway GO:0097190 306 0.019
anion transport GO:0006820 177 0.019
protein catabolic process GO:0030163 221 0.019
Mouse
metal ion homeostasis GO:0055065 189 0.019
negative regulation of immune system process GO:0002683 209 0.018
Mouse
positive regulation of nervous system development GO:0051962 221 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
t cell activation GO:0042110 289 0.018
cell type specific apoptotic process GO:0097285 268 0.018
protein maturation GO:0051604 176 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
membrane organization GO:0061024 245 0.018
cytoplasmic transport GO:0016482 234 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
protein secretion GO:0009306 111 0.018
ras protein signal transduction GO:0007265 77 0.018
camera type eye development GO:0043010 266 0.018
sensory organ morphogenesis GO:0090596 242 0.017
skeletal system development GO:0001501 356 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
nucleotide metabolic process GO:0009117 332 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
regulation of cell motility GO:2000145 236 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
protein processing GO:0016485 163 0.017
organic anion transport GO:0015711 137 0.017
purine containing compound metabolic process GO:0072521 311 0.017
regulation of ion transport GO:0043269 215 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
male gamete generation GO:0048232 285 0.017
cellular homeostasis GO:0019725 240 0.017
cellular ion homeostasis GO:0006873 165 0.017
cell adhesion GO:0007155 329 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
regulation of intracellular transport GO:0032386 159 0.017
positive regulation of cytokine production GO:0001819 174 0.017
blood circulation GO:0008015 195 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
muscle tissue development GO:0060537 308 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.016
leukocyte activation involved in immune response GO:0002366 126 0.016
rho protein signal transduction GO:0007266 32 0.016
circulatory system process GO:0003013 197 0.016
chemotaxis GO:0006935 247 0.016
homeostasis of number of cells GO:0048872 210 0.016
Mouse
carbohydrate metabolic process GO:0005975 230 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
Mouse
response to amino acid GO:0043200 37 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
regulation of transferase activity GO:0051338 263 0.016
regulation of body fluid levels GO:0050878 162 0.016
regulation of organelle organization GO:0033043 289 0.016
Mouse
detection of stimulus GO:0051606 84 0.016
regulation of homeostatic process GO:0032844 182 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
stem cell development GO:0048864 219 0.016
forebrain development GO:0030900 302 0.016
maintenance of location GO:0051235 89 0.016
leukocyte migration GO:0050900 124 0.015
regulation of transmembrane transport GO:0034762 128 0.015
stem cell differentiation GO:0048863 268 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
regulation of mapk cascade GO:0043408 248 0.015
ossification GO:0001503 216 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
response to acid chemical GO:0001101 111 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
Mouse
carbohydrate homeostasis GO:0033500 128 0.015
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.015
axonogenesis GO:0007409 274 0.015
heterocycle catabolic process GO:0046700 280 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.015
negative regulation of cell development GO:0010721 169 0.015
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.015
regulation of protein transport GO:0051223 163 0.015
anatomical structure homeostasis GO:0060249 145 0.015
aromatic compound catabolic process GO:0019439 286 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
positive regulation of cell development GO:0010720 237 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
striated muscle tissue development GO:0014706 293 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
locomotory behavior GO:0007626 195 0.014
spermatogenesis GO:0007283 284 0.014
lymphocyte differentiation GO:0030098 242 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
amide transport GO:0042886 138 0.014
mapk cascade GO:0000165 281 0.014
positive regulation of cell activation GO:0050867 158 0.014
regulation of neuron differentiation GO:0045664 281 0.014
regulation of cell migration GO:0030334 219 0.014
axon ensheathment GO:0008366 76 0.014
nucleoside metabolic process GO:0009116 246 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
regulation of anatomical structure size GO:0090066 178 0.014
Mouse
negative regulation of nervous system development GO:0051961 156 0.014
Mouse
response to organic cyclic compound GO:0014070 198 0.014
cell activation involved in immune response GO:0002263 126 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
Mouse
glucose homeostasis GO:0042593 128 0.014
germ cell development GO:0007281 185 0.014
organic acid transport GO:0015849 101 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
leukocyte mediated immunity GO:0002443 174 0.014
regulation of blood pressure GO:0008217 93 0.014
cellular response to amino acid stimulus GO:0071230 29 0.014
microtubule based process GO:0007017 236 0.014
protein localization to organelle GO:0033365 185 0.014
ensheathment of neurons GO:0007272 76 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.013
b cell activation GO:0042113 161 0.013
activation of immune response GO:0002253 138 0.013
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.013
intracellular protein transport GO:0006886 204 0.013
skin development GO:0043588 220 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
developmental maturation GO:0021700 193 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
glycoprotein metabolic process GO:0009100 116 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
Mouse
synaptic transmission GO:0007268 329 0.013
multicellular organism growth GO:0035264 161 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
regulation of kinase activity GO:0043549 249 0.013
tissue homeostasis GO:0001894 115 0.013
regulation of system process GO:0044057 200 0.013
rhythmic process GO:0048511 174 0.013
negative regulation of protein modification process GO:0031400 163 0.013
cellular response to acid chemical GO:0071229 68 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
leukocyte proliferation GO:0070661 172 0.013
carboxylic acid transport GO:0046942 100 0.013
myelination GO:0042552 74 0.013
positive regulation of defense response GO:0031349 124 0.013
Mouse
positive regulation of transferase activity GO:0051347 167 0.013
regulation of hydrolase activity GO:0051336 246 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
cellular protein catabolic process GO:0044257 155 0.012
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.012
positive regulation of kinase activity GO:0033674 155 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
regulation of cell cycle GO:0051726 281 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
extracellular matrix organization GO:0030198 147 0.012
cytokine secretion GO:0050663 72 0.012
glial cell differentiation GO:0010001 131 0.012
angiogenesis GO:0001525 201 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
cognition GO:0050890 149 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
gliogenesis GO:0042063 141 0.012
positive regulation of cell motility GO:2000147 116 0.012
ear development GO:0043583 200 0.012
calcium ion homeostasis GO:0055074 127 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
regulation of multi organism process GO:0043900 111 0.012
Mouse
purine nucleoside metabolic process GO:0042278 241 0.012
sequestering of calcium ion GO:0051208 18 0.012
positive regulation of cell death GO:0010942 224 0.012
lipid localization GO:0010876 126 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
glycerolipid metabolic process GO:0046486 122 0.012
wnt signaling pathway GO:0016055 188 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
single organism cell adhesion GO:0098602 156 0.012
response to extracellular stimulus GO:0009991 127 0.012
extracellular structure organization GO:0043062 148 0.012
telencephalon development GO:0021537 186 0.012
endocytosis GO:0006897 168 0.012
regulation of cell adhesion GO:0030155 154 0.012
defense response to bacterium GO:0042742 119 0.012
multi multicellular organism process GO:0044706 109 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
response to growth factor GO:0070848 198 0.012
placenta development GO:0001890 140 0.012
regulation of protein kinase activity GO:0045859 232 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
lymphocyte proliferation GO:0046651 164 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
positive regulation of protein transport GO:0051222 93 0.012
epithelial cell proliferation GO:0050673 174 0.012
response to inorganic substance GO:0010035 96 0.011
regulation of proteolysis GO:0030162 164 0.011
sequestering of metal ion GO:0051238 19 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
Mouse
urogenital system development GO:0001655 261 0.011
positive regulation of secretion GO:0051047 130 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
dna metabolic process GO:0006259 303 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
mitotic cell cycle GO:0000278 195 0.011
positive regulation of innate immune response GO:0045089 80 0.011
Mouse
lipid transport GO:0006869 98 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
cell maturation GO:0048469 127 0.011
organic hydroxy compound transport GO:0015850 93 0.011
regulation of t cell activation GO:0050863 170 0.011
divalent inorganic cation transport GO:0072511 178 0.011
fertilization GO:0009566 127 0.011
nuclear transport GO:0051169 139 0.011
endomembrane system organization GO:0010256 147 0.011
divalent metal ion transport GO:0070838 172 0.011
positive regulation of immune effector process GO:0002699 107 0.011
limb development GO:0060173 166 0.011
dephosphorylation GO:0016311 129 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
Mouse
regulation of protein secretion GO:0050708 82 0.011
t cell differentiation GO:0030217 174 0.011
adaptive immune response GO:0002250 155 0.011
mitotic cell cycle process GO:1903047 159 0.011
regulation of action potential GO:0098900 4 0.011
learning or memory GO:0007611 148 0.011
gland development GO:0048732 330 0.011
hormone secretion GO:0046879 128 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
Mouse
production of molecular mediator of immune response GO:0002440 103 0.011
response to nutrient levels GO:0031667 109 0.011
cytokine metabolic process GO:0042107 71 0.011
organelle localization GO:0051640 179 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
tissue remodeling GO:0048771 102 0.011
exocytosis GO:0006887 121 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
engulfment of apoptotic cell GO:0043652 3 0.010
peptide hormone secretion GO:0030072 109 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
Mouse
peptide transport GO:0015833 133 0.010
ribonucleoside metabolic process GO:0009119 245 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
regulation of cell projection organization GO:0031344 206 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
response to peptide GO:1901652 136 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
regulation of feeding behavior GO:0060259 3 0.010
regulation of cytoskeleton organization GO:0051493 122 0.010
Mouse
epithelial cell development GO:0002064 159 0.010
calcium ion transport GO:0006816 159 0.010
protein targeting GO:0006605 143 0.010
skeletal system morphogenesis GO:0048705 203 0.010
lipid biosynthetic process GO:0008610 179 0.010
regulation of protein catabolic process GO:0042176 108 0.010
Mouse
regulation of ossification GO:0030278 112 0.010

Trim58 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
central nervous system disease DOID:331 0 0.014
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010