Mus musculus

74 known processes

Trim56

tripartite motif-containing 56

(Aliases: Gm452,A130009K11Rik,RNF109,MGC37358)

Trim56 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cytokine production GO:0001817 266 0.077
immune effector process GO:0002252 321 0.067
cytokine production GO:0001816 319 0.065
regulation of defense response GO:0031347 233 0.064
activation of immune response GO:0002253 138 0.055
interspecies interaction between organisms GO:0044419 83 0.055
protein modification by small protein conjugation GO:0032446 187 0.052
macromolecule catabolic process GO:0009057 281 0.050
cellular amino acid metabolic process GO:0006520 103 0.050
cellular amine metabolic process GO:0044106 44 0.048
protein modification by small protein conjugation or removal GO:0070647 207 0.048
viral process GO:0016032 41 0.045
organic cyclic compound catabolic process GO:1901361 295 0.044
protein ubiquitination GO:0016567 171 0.044
amine metabolic process GO:0009308 45 0.044
innate immune response GO:0045087 157 0.044
aromatic compound catabolic process GO:0019439 286 0.043
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
negative regulation of molecular function GO:0044092 258 0.041
regulation of cellular amine metabolic process GO:0033238 20 0.039
immune response activating signal transduction GO:0002757 116 0.038
nucleoside phosphate metabolic process GO:0006753 338 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
cellular macromolecule catabolic process GO:0044265 206 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
cellular ketone metabolic process GO:0042180 84 0.035
regulation of innate immune response GO:0045088 91 0.034
regulation of multi organism process GO:0043900 111 0.034
mapk cascade GO:0000165 281 0.034
protein catabolic process GO:0030163 221 0.033
positive regulation of cytokine production GO:0001819 174 0.033
defense response to virus GO:0051607 68 0.033
regulation of organelle organization GO:0033043 289 0.032
regulation of cellular ketone metabolic process GO:0010565 66 0.032
nucleotide metabolic process GO:0009117 332 0.031
immune response regulating signaling pathway GO:0002764 125 0.031
negative regulation of protein metabolic process GO:0051248 282 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
regulation of protein localization GO:0032880 231 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.030
positive regulation of innate immune response GO:0045089 80 0.030
myeloid cell differentiation GO:0030099 233 0.030
oxidation reduction process GO:0055114 342 0.029
small gtpase mediated signal transduction GO:0007264 97 0.029
ras protein signal transduction GO:0007265 77 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
dna metabolic process GO:0006259 303 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
reactive oxygen species metabolic process GO:0072593 84 0.027
activation of innate immune response GO:0002218 56 0.027
peptidyl amino acid modification GO:0018193 336 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
apoptotic signaling pathway GO:0097190 306 0.026
chromatin organization GO:0006325 206 0.026
negative regulation of cell development GO:0010721 169 0.026
negative regulation of cellular component organization GO:0051129 194 0.026
ossification GO:0001503 216 0.026
intracellular protein transport GO:0006886 204 0.026
cellular protein catabolic process GO:0044257 155 0.026
heterocycle catabolic process GO:0046700 280 0.026
ribonucleotide metabolic process GO:0009259 291 0.025
negative regulation of immune system process GO:0002683 209 0.025
positive regulation of interleukin 8 production GO:0032757 2 0.025
transmembrane transport GO:0055085 412 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
purine containing compound metabolic process GO:0072521 311 0.025
cellular response to lipid GO:0071396 145 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
regulation of establishment of protein localization GO:0070201 181 0.024
interleukin 8 production GO:0032637 4 0.023
negative regulation of protein modification process GO:0031400 163 0.023
membrane organization GO:0061024 245 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
response to organonitrogen compound GO:0010243 246 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
leukocyte differentiation GO:0002521 342 0.023
ion transmembrane transport GO:0034220 361 0.023
regulation of interleukin 8 production GO:0032677 3 0.023
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.023
response to organic cyclic compound GO:0014070 198 0.023
nucleocytoplasmic transport GO:0006913 139 0.022
cation transport GO:0006812 399 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
histone modification GO:0016570 159 0.022
cytoplasmic transport GO:0016482 234 0.022
anion transport GO:0006820 177 0.022
modification dependent macromolecule catabolic process GO:0043632 133 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
covalent chromatin modification GO:0016569 163 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
t cell activation GO:0042110 289 0.022
positive regulation of defense response GO:0031349 124 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
regulation of cell activation GO:0050865 289 0.021
nucleoside metabolic process GO:0009116 246 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
positive regulation of protein modification process GO:0031401 299 0.021
chromatin modification GO:0016568 187 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
carbohydrate metabolic process GO:0005975 230 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
spermatogenesis GO:0007283 284 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
regulation of mapk cascade GO:0043408 248 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
cation transmembrane transport GO:0098655 266 0.020
cellular lipid metabolic process GO:0044255 323 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
negative regulation of nervous system development GO:0051961 156 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
regulation of intracellular transport GO:0032386 159 0.020
homeostasis of number of cells GO:0048872 210 0.019
respiratory system development GO:0060541 190 0.019
protein targeting GO:0006605 143 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
nuclear transport GO:0051169 139 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
negative regulation of multi organism process GO:0043901 68 0.019
myeloid cell homeostasis GO:0002262 114 0.019
actin cytoskeleton organization GO:0030036 220 0.019
rho protein signal transduction GO:0007266 32 0.019
defense response to other organism GO:0098542 197 0.019
regulation of hydrolase activity GO:0051336 246 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
male gamete generation GO:0048232 285 0.018
striated muscle tissue development GO:0014706 293 0.018
regulation of cellular response to stress GO:0080135 159 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
negative regulation of defense response GO:0031348 77 0.018
synaptic transmission GO:0007268 329 0.018
divalent inorganic cation transport GO:0072511 178 0.018
nucleotide catabolic process GO:0009166 217 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
nucleoside catabolic process GO:0009164 206 0.018
positive regulation of viral entry into host cell GO:0046598 3 0.018
purine containing compound catabolic process GO:0072523 213 0.017
defense response to bacterium GO:0042742 119 0.017
response to lipopolysaccharide GO:0032496 128 0.017
regulation of membrane potential GO:0042391 192 0.017
nitrogen compound transport GO:0071705 271 0.017
regulation of t cell activation GO:0050863 170 0.017
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.017
cellular protein complex assembly GO:0043623 116 0.017
positive regulation of interferon alpha production GO:0032727 4 0.017
regulation of transferase activity GO:0051338 263 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
response to oxidative stress GO:0006979 123 0.017
regulation of protein complex assembly GO:0043254 83 0.017
protein localization to organelle GO:0033365 185 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
protein localization to nucleus GO:0034504 121 0.016
microtubule based process GO:0007017 236 0.016
regulation of protein transport GO:0051223 163 0.016
organophosphate catabolic process GO:0046434 232 0.016
cell type specific apoptotic process GO:0097285 268 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
organelle localization GO:0051640 179 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
compound eye development GO:0048749 1 0.016
pattern recognition receptor signaling pathway GO:0002221 47 0.016
regulation of response to wounding GO:1903034 189 0.016
regulation of body fluid levels GO:0050878 162 0.016
single organism nuclear import GO:1902593 95 0.016
lung development GO:0030324 164 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
positive regulation of organelle organization GO:0010638 128 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
gland development GO:0048732 330 0.016
sensory perception GO:0007600 245 0.015
muscle tissue development GO:0060537 308 0.015
germ cell development GO:0007281 185 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
cellular homeostasis GO:0019725 240 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
interleukin 6 production GO:0032635 58 0.015
regulation of interleukin 6 production GO:0032675 55 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
endocytosis GO:0006897 168 0.015
viral gene expression GO:0019080 3 0.015
cofactor metabolic process GO:0051186 80 0.015
rna processing GO:0006396 105 0.015
leukocyte proliferation GO:0070661 172 0.015
regulation of protein catabolic process GO:0042176 108 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
respiratory tube development GO:0030323 167 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
blood vessel morphogenesis GO:0048514 285 0.015
lymphocyte proliferation GO:0046651 164 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
ribonucleoside catabolic process GO:0042454 206 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
regulation of response to biotic stimulus GO:0002831 38 0.014
mrna metabolic process GO:0016071 84 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
inflammatory response GO:0006954 244 0.014
skeletal system development GO:0001501 356 0.014
dephosphorylation GO:0016311 129 0.014
maintenance of location GO:0051235 89 0.014
regulation of system process GO:0044057 200 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
regulation of actin nucleation GO:0051125 4 0.014
organelle assembly GO:0070925 177 0.014
wnt signaling pathway GO:0016055 188 0.014
neuronal action potential GO:0019228 54 0.014
protein import GO:0017038 101 0.014
actin polymerization or depolymerization GO:0008154 54 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
positive regulation of immune effector process GO:0002699 107 0.014
protein import into nucleus GO:0006606 95 0.014
negative regulation of viral process GO:0048525 23 0.014
stem cell differentiation GO:0048863 268 0.014
regulation of kinase activity GO:0043549 249 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
wound healing GO:0042060 157 0.014
muscle cell differentiation GO:0042692 261 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
fat cell differentiation GO:0045444 160 0.014
protein processing GO:0016485 163 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
cell adhesion GO:0007155 329 0.014
organic hydroxy compound transport GO:0015850 93 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
leukocyte mediated immunity GO:0002443 174 0.014
regulation of ossification GO:0030278 112 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
positive regulation of viral genome replication GO:0045070 2 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
transmission of nerve impulse GO:0019226 76 0.013
t cell proliferation GO:0042098 120 0.013
carbohydrate homeostasis GO:0033500 128 0.013
urogenital system development GO:0001655 261 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
divalent metal ion transport GO:0070838 172 0.013
gtp catabolic process GO:0006184 143 0.013
actin filament organization GO:0007015 113 0.013
innate immune response activating signal transduction GO:0002758 50 0.013
negative regulation of cytokine production GO:0001818 84 0.013
regulation of cell cycle GO:0051726 281 0.013
positive regulation of cell death GO:0010942 224 0.013
epithelial cell proliferation GO:0050673 174 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.013
regulation of organ morphogenesis GO:2000027 144 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
spermatid differentiation GO:0048515 115 0.013
lymphocyte differentiation GO:0030098 242 0.013
protein maturation GO:0051604 176 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
lipid biosynthetic process GO:0008610 179 0.013
regulation of ion transport GO:0043269 215 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
type i interferon production GO:0032606 29 0.013
renal system development GO:0072001 225 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
cation homeostasis GO:0055080 212 0.013
fertilization GO:0009566 127 0.013
lipid transport GO:0006869 98 0.013
i kappab kinase nf kappab signaling GO:0007249 85 0.013
forebrain development GO:0030900 302 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
alcohol metabolic process GO:0006066 116 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.013
regulation of cell migration GO:0030334 219 0.013
multicellular organismal signaling GO:0035637 91 0.013
cellular chemical homeostasis GO:0055082 215 0.012
action potential GO:0001508 78 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
response to extracellular stimulus GO:0009991 127 0.012
response to acid chemical GO:0001101 111 0.012
positive regulation of nervous system development GO:0051962 221 0.012
regulation of cellular component size GO:0032535 121 0.012
mitotic cell cycle GO:0000278 195 0.012
regulation of hormone levels GO:0010817 211 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
viral transcription GO:0019083 3 0.012
negative regulation of organelle organization GO:0010639 90 0.012
regulation of secretion GO:0051046 274 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.012
plasma membrane organization GO:0007009 90 0.012
regulation of inflammatory response GO:0050727 147 0.012
regulation of neuron differentiation GO:0045664 281 0.012
small molecule biosynthetic process GO:0044283 132 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
response to endoplasmic reticulum stress GO:0034976 53 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
cell activation involved in immune response GO:0002263 126 0.012
nuclear import GO:0051170 95 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
angiogenesis GO:0001525 201 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
digestive system development GO:0055123 200 0.012
positive regulation of protein catabolic process GO:0045732 60 0.012
chemotaxis GO:0006935 247 0.012
cellular ion homeostasis GO:0006873 165 0.012
endomembrane system organization GO:0010256 147 0.012
actin filament polymerization GO:0030041 44 0.012
protein polymerization GO:0051258 57 0.012
sensory organ morphogenesis GO:0090596 242 0.012
regulation of proteolysis GO:0030162 164 0.012
regulation of secretion by cell GO:1903530 249 0.012
response to oxygen levels GO:0070482 62 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
regulation of cell motility GO:2000145 236 0.012
rna interference GO:0016246 2 0.011
organic anion transport GO:0015711 137 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
muscle system process GO:0003012 141 0.011
positive regulation of protein transport GO:0051222 93 0.011
regulation of anatomical structure size GO:0090066 178 0.011
rna catabolic process GO:0006401 29 0.011
response to growth factor GO:0070848 198 0.011
protein localization to membrane GO:0072657 108 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
mitotic cytokinesis GO:0000281 4 0.011
anatomical structure homeostasis GO:0060249 145 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
regulation of protein targeting GO:1903533 61 0.011
regulation of cell cycle process GO:0010564 160 0.011
ear development GO:0043583 200 0.011
erythrocyte differentiation GO:0030218 88 0.011
extracellular structure organization GO:0043062 148 0.011
dna repair GO:0006281 107 0.011
kidney development GO:0001822 213 0.011
lateral inhibition GO:0046331 1 0.011
vesicle localization GO:0051648 86 0.011
regulation of viral transcription GO:0046782 3 0.011
skin development GO:0043588 220 0.011
regulation of feeding behavior GO:0060259 3 0.011
mitotic cell cycle process GO:1903047 159 0.011
multicellular organism growth GO:0035264 161 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
regulation of cell projection organization GO:0031344 206 0.011
oocyte construction GO:0007308 2 0.011
negative regulation of viral transcription GO:0032897 3 0.011
positive regulation of cell development GO:0010720 237 0.011
muscle cell development GO:0055001 133 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
nuclear division GO:0000280 158 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
tissue homeostasis GO:0001894 115 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
sequestering of calcium ion GO:0051208 18 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
camera type eye development GO:0043010 266 0.011
pharynx development GO:0060465 1 0.011
organelle fission GO:0048285 170 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
response to peptide GO:1901652 136 0.010
positive regulation of actin nucleation GO:0051127 3 0.010
response to nutrient levels GO:0031667 109 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
tissue remodeling GO:0048771 102 0.010
glucose homeostasis GO:0042593 128 0.010
methylation GO:0032259 134 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
neuron death GO:0070997 154 0.010
membrane tubulation GO:0097320 4 0.010
positive regulation of cell activation GO:0050867 158 0.010
axonogenesis GO:0007409 274 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
telencephalon development GO:0021537 186 0.010
cytokinetic process GO:0032506 2 0.010
t cell differentiation GO:0030217 174 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
regionalization GO:0003002 337 0.010
negative regulation of growth GO:0045926 99 0.010
metal ion homeostasis GO:0055065 189 0.010
cell division GO:0051301 120 0.010
organic acid biosynthetic process GO:0016053 86 0.010

Trim56 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.020
organ system cancer DOID:0050686 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
disease of metabolism DOID:0014667 0 0.019
nervous system disease DOID:863 0 0.018
disease of anatomical entity DOID:7 0 0.018
immune system disease DOID:2914 0 0.016
hematopoietic system disease DOID:74 0 0.013
connective tissue disease DOID:65 0 0.011
musculoskeletal system disease DOID:17 0 0.011
bone disease DOID:0080001 0 0.011
central nervous system disease DOID:331 0 0.010