Mus musculus

0 known processes

Mmadhc

methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria

(Aliases: 2010311D03Rik,AI314967)

Mmadhc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteasomal protein catabolic process GO:0010498 98 0.122
glycosyl compound metabolic process GO:1901657 246 0.117
mitochondrion organization GO:0007005 134 0.088
purine ribonucleoside metabolic process GO:0046128 241 0.073
nucleobase containing small molecule metabolic process GO:0055086 352 0.069
protein processing GO:0016485 163 0.068
cellular ketone metabolic process GO:0042180 84 0.067
nucleoside triphosphate catabolic process GO:0009143 205 0.066
purine ribonucleotide metabolic process GO:0009150 290 0.062
protein catabolic process GO:0030163 221 0.053
lipid biosynthetic process GO:0008610 179 0.053
cofactor metabolic process GO:0051186 80 0.052
protein modification by small protein conjugation or removal GO:0070647 207 0.050
protein maturation GO:0051604 176 0.048
protein localization to organelle GO:0033365 185 0.048
macromolecule catabolic process GO:0009057 281 0.047
ubiquitin dependent protein catabolic process GO:0006511 129 0.045
amine metabolic process GO:0009308 45 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.038
cellular response to dna damage stimulus GO:0006974 207 0.038
negative regulation of intracellular signal transduction GO:1902532 167 0.037
cytoplasmic transport GO:0016482 234 0.037
ribonucleotide catabolic process GO:0009261 208 0.036
protein targeting GO:0006605 143 0.035
cellular amine metabolic process GO:0044106 44 0.034
regulation of hydrolase activity GO:0051336 246 0.033
negative regulation of cellular component organization GO:0051129 194 0.033
cellular protein catabolic process GO:0044257 155 0.033
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
cellular macromolecule catabolic process GO:0044265 206 0.033
modification dependent protein catabolic process GO:0019941 133 0.032
positive regulation of hydrolase activity GO:0051345 148 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.032
mitotic cell cycle GO:0000278 195 0.031
small molecule biosynthetic process GO:0044283 132 0.031
protein import GO:0017038 101 0.031
nucleotide catabolic process GO:0009166 217 0.031
atp metabolic process GO:0046034 75 0.030
sulfur compound biosynthetic process GO:0044272 37 0.030
dna metabolic process GO:0006259 303 0.029
protein modification by small protein conjugation GO:0032446 187 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.028
intracellular protein transport GO:0006886 204 0.028
transmembrane transport GO:0055085 412 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.028
peptidyl amino acid modification GO:0018193 336 0.028
purine containing compound catabolic process GO:0072523 213 0.028
modification dependent macromolecule catabolic process GO:0043632 133 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
positive regulation of cellular catabolic process GO:0031331 148 0.025
regulation of cellular amine metabolic process GO:0033238 20 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.025
negative regulation of apoptotic signaling pathway GO:2001234 104 0.025
regulation of protein kinase activity GO:0045859 232 0.024
apoptotic mitochondrial changes GO:0008637 48 0.024
ion transmembrane transport GO:0034220 361 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
localization within membrane GO:0051668 4 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
organophosphate catabolic process GO:0046434 232 0.023
apoptotic signaling pathway GO:0097190 306 0.023
cellular protein complex assembly GO:0043623 116 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
mitotic cell cycle process GO:1903047 159 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
protein neddylation GO:0045116 1 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
nitrogen compound transport GO:0071705 271 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
membrane organization GO:0061024 245 0.021
nucleoside catabolic process GO:0009164 206 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
regulation of cellular response to stress GO:0080135 159 0.020
regulation of cell cycle GO:0051726 281 0.020
metal ion homeostasis GO:0055065 189 0.020
nucleotide metabolic process GO:0009117 332 0.020
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.020
regulation of proteolysis GO:0030162 164 0.020
male gamete generation GO:0048232 285 0.020
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
phosphatidylethanolamine metabolic process GO:0046337 2 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
cellular amino acid metabolic process GO:0006520 103 0.020
spermatogenesis GO:0007283 284 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
t cell activation GO:0042110 289 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
regulation of cellular amino acid metabolic process GO:0006521 5 0.019
regulation of cell growth GO:0001558 91 0.019
cellular lipid metabolic process GO:0044255 323 0.019
translation GO:0006412 93 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
small gtpase mediated signal transduction GO:0007264 97 0.018
cellular homeostasis GO:0019725 240 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
cell growth GO:0016049 130 0.018
stem cell differentiation GO:0048863 268 0.018
regulation of organelle organization GO:0033043 289 0.018
nucleoside metabolic process GO:0009116 246 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
sulfur compound metabolic process GO:0006790 100 0.017
response to oxidative stress GO:0006979 123 0.017
heterocycle catabolic process GO:0046700 280 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
regulation of cell cycle process GO:0010564 160 0.017
regulation of cell migration GO:0030334 219 0.017
mapk cascade GO:0000165 281 0.017
exocytosis GO:0006887 121 0.017
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
positive regulation of protein modification process GO:0031401 299 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.016
t cell proliferation GO:0042098 120 0.016
mitochondrion degradation GO:0000422 3 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
synaptic transmission GO:0007268 329 0.016
neural tube formation GO:0001841 108 0.016
ossification GO:0001503 216 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
calcium ion transport GO:0006816 159 0.016
skeletal system development GO:0001501 356 0.016
locomotory behavior GO:0007626 195 0.016
negative regulation of cell development GO:0010721 169 0.016
regulation of nucleotide catabolic process GO:0030811 122 0.016
tube formation GO:0035148 140 0.016
positive regulation of protein catabolic process GO:0045732 60 0.015
regulation of protein maturation GO:1903317 96 0.015
maintenance of location GO:0051235 89 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
regulation of protein targeting GO:1903533 61 0.015
protein import into nucleus GO:0006606 95 0.015
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
amide transport GO:0042886 138 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
regulation of protein catabolic process GO:0042176 108 0.015
regulation of cell motility GO:2000145 236 0.015
copii coated vesicle budding GO:0090114 2 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.014
divalent metal ion transport GO:0070838 172 0.014
chromatin organization GO:0006325 206 0.014
epithelial tube formation GO:0072175 130 0.014
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.014
er associated ubiquitin dependent protein catabolic process GO:0030433 10 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
organelle assembly GO:0070925 177 0.014
response to inorganic substance GO:0010035 96 0.014
regulation of cellular ketone metabolic process GO:0010565 66 0.014
regulation of secretion by cell GO:1903530 249 0.014
glycerophospholipid biosynthetic process GO:0046474 32 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
organelle fusion GO:0048284 28 0.014
single organism cell adhesion GO:0098602 156 0.014
inflammatory response GO:0006954 244 0.014
positive regulation of cell death GO:0010942 224 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
regulation of hormone levels GO:0010817 211 0.013
spermatid development GO:0007286 108 0.013
neural tube development GO:0021915 160 0.013
stem cell development GO:0048864 219 0.013
aromatic compound catabolic process GO:0019439 286 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
organic acid biosynthetic process GO:0016053 86 0.013
regulation of kinase activity GO:0043549 249 0.013
divalent inorganic cation transport GO:0072511 178 0.013
camera type eye development GO:0043010 266 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
negative regulation of growth GO:0045926 99 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
sensory organ morphogenesis GO:0090596 242 0.013
leukocyte migration GO:0050900 124 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
regulation of peptide transport GO:0090087 91 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
cation homeostasis GO:0055080 212 0.013
gtp metabolic process GO:0046039 144 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
sequestering of calcium ion GO:0051208 18 0.013
negative regulation of alcohol biosynthetic process GO:1902931 4 0.013
protein oligomerization GO:0051259 67 0.013
wound healing GO:0042060 157 0.013
germ cell development GO:0007281 185 0.012
covalent chromatin modification GO:0016569 163 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
cation transport GO:0006812 399 0.012
proteasomal ubiquitin independent protein catabolic process GO:0010499 1 0.012
prenylation GO:0097354 3 0.012
glycerolipid biosynthetic process GO:0045017 50 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
atp catabolic process GO:0006200 55 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
regulation of anatomical structure size GO:0090066 178 0.012
stem cell maintenance GO:0019827 130 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
peptide transport GO:0015833 133 0.011
double strand break repair GO:0006302 48 0.011
regulation of membrane potential GO:0042391 192 0.011
purine containing compound metabolic process GO:0072521 311 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
positive regulation of transferase activity GO:0051347 167 0.011
nuclear import GO:0051170 95 0.011
cell cycle g1 s phase transition GO:0044843 57 0.011
gene silencing GO:0016458 38 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
blastocyst development GO:0001824 80 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
protein folding GO:0006457 28 0.011
regulation of peptidase activity GO:0052547 96 0.011
regulation of intracellular transport GO:0032386 159 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
negative regulation of molecular function GO:0044092 258 0.011
cell adhesion GO:0007155 329 0.011
regulation of cell activation GO:0050865 289 0.011
negative regulation of immune system process GO:0002683 209 0.011
wnt signaling pathway GO:0016055 188 0.011
positive regulation of organelle organization GO:0010638 128 0.011
lipid localization GO:0010876 126 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
response to extracellular stimulus GO:0009991 127 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
positive regulation of kinase activity GO:0033674 155 0.011
regulation of homeostatic process GO:0032844 182 0.011
protein ubiquitination GO:0016567 171 0.011
regulation of secretion GO:0051046 274 0.010
cellular response to oxidative stress GO:0034599 76 0.010
regulation of mitochondrion organization GO:0010821 27 0.010
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
cation transmembrane transport GO:0098655 266 0.010
response to radiation GO:0009314 165 0.010
fertilization GO:0009566 127 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
g1 s transition of mitotic cell cycle GO:0000082 57 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
dna repair GO:0006281 107 0.010

Mmadhc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012