Mus musculus

167 known processes

Hspa5

heat shock protein 5

(Aliases: D2Wsu141e,mBiP,SEZ-7,AL022860,Hsce70,AU019543,Grp78,D2Wsu17e,Sez7,Bip)

Hspa5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to topologically incorrect protein GO:0035966 25 1.000
response to endoplasmic reticulum stress GO:0034976 53 1.000
endoplasmic reticulum unfolded protein response GO:0030968 19 0.999
cellular response to topologically incorrect protein GO:0035967 25 0.998
response to unfolded protein GO:0006986 21 0.996
er nucleus signaling pathway GO:0006984 27 0.992
cellular macromolecule catabolic process GO:0044265 206 0.862
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.848
Yeast
protein refolding GO:0042026 1 0.767
protein n linked glycosylation via asparagine GO:0018279 1 0.691
chaperone mediated protein folding GO:0061077 10 0.671
modification dependent protein catabolic process GO:0019941 133 0.612
Yeast
midgut development GO:0007494 4 0.589
cellular response to interleukin 4 GO:0071353 21 0.561
b cell activation involved in immune response GO:0002312 50 0.545
protein folding GO:0006457 28 0.541
positive regulation of programmed cell death GO:0043068 218 0.526
lipid storage GO:0019915 36 0.457
Worm
fertilization GO:0009566 127 0.453
de novo protein folding GO:0006458 9 0.453
response to organonitrogen compound GO:0010243 246 0.424
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.408
protein catabolic process GO:0030163 221 0.362
response to organic cyclic compound GO:0014070 198 0.359
male genitalia morphogenesis GO:0048808 4 0.346
positive regulation of apoptotic signaling pathway GO:2001235 95 0.341
glycoprotein biosynthetic process GO:0009101 89 0.336
endodermal digestive tract morphogenesis GO:0061031 4 0.335
positive regulation of apoptotic process GO:0043065 217 0.335
sensory organ morphogenesis GO:0090596 242 0.333
spermatogenesis GO:0007283 284 0.325
protein targeting GO:0006605 143 0.320
Yeast
regulation of secretion by cell GO:1903530 249 0.317
regulation of interleukin 6 production GO:0032675 55 0.314
regulation of apoptotic signaling pathway GO:2001233 197 0.296
protein targeting to mitochondrion GO:0006626 6 0.287
regulation of protein transport GO:0051223 163 0.273
protein localization to organelle GO:0033365 185 0.266
Human Yeast
positive regulation of growth GO:0045927 104 0.265
positive regulation of interleukin 6 secretion GO:2000778 1 0.257
organelle disassembly GO:1903008 2 0.242
interleukin 6 secretion GO:0072604 3 0.238
proteasomal protein catabolic process GO:0010498 98 0.231
Yeast
response to atp GO:0033198 8 0.225
digestive tract morphogenesis GO:0048546 147 0.221
apoptotic signaling pathway GO:0097190 306 0.219
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.204
extrinsic apoptotic signaling pathway GO:0097191 126 0.204
glycoprotein metabolic process GO:0009100 116 0.201
retina homeostasis GO:0001895 23 0.197
protein targeting to membrane GO:0006612 20 0.196
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 220 0.193
Yeast
maintenance of location GO:0051235 89 0.190
Human Worm
male gamete generation GO:0048232 285 0.188
muscle cell differentiation GO:0042692 261 0.186
response to heat GO:0009408 27 0.181
translation GO:0006412 93 0.177
interleukin 6 production GO:0032635 58 0.172
posttranscriptional regulation of gene expression GO:0010608 155 0.172
ubiquitin dependent protein catabolic process GO:0006511 129 0.167
Yeast
metencephalon development GO:0022037 89 0.166
cellular response to cytokine stimulus GO:0071345 189 0.164
male sex differentiation GO:0046661 109 0.163
striated muscle myosin thick filament assembly GO:0071688 1 0.163
ribonucleoside catabolic process GO:0042454 206 0.159
Yeast
positive regulation of cell activation GO:0050867 158 0.157
myosin filament organization GO:0031033 3 0.153
macromolecule catabolic process GO:0009057 281 0.152
regulation of cytokine production GO:0001817 266 0.152
spermatid differentiation GO:0048515 115 0.149
circulatory system process GO:0003013 197 0.149
germ cell development GO:0007281 185 0.148
protein transmembrane transport GO:0071806 8 0.147
Yeast
regulation of cellular response to stress GO:0080135 159 0.144
sperm egg recognition GO:0035036 37 0.143
multicellular organism growth GO:0035264 161 0.140
dna metabolic process GO:0006259 303 0.137
positive regulation of cardiac muscle contraction GO:0060452 2 0.134
multi organism reproductive behavior GO:0044705 29 0.133
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.131
regulation of protein exit from endoplasmic reticulum GO:0070861 1 0.125
single fertilization GO:0007338 82 0.124
regulation of transposition GO:0010528 2 0.120
regulation of protein localization GO:0032880 231 0.118
regulation of protein secretion GO:0050708 82 0.117
positive regulation of t cell activation GO:0050870 101 0.117
regulation of organ morphogenesis GO:2000027 144 0.114
regulation of establishment of protein localization GO:0070201 181 0.109
immunoglobulin production GO:0002377 73 0.107
cytokine production GO:0001816 319 0.106
nucleoside triphosphate catabolic process GO:0009143 205 0.105
Yeast
positive regulation of cell death GO:0010942 224 0.105
ribonucleotide metabolic process GO:0009259 291 0.104
Yeast
negative regulation of transposition GO:0010529 2 0.104
lymphocyte activation involved in immune response GO:0002285 93 0.102
cytoplasmic transport GO:0016482 234 0.102
Yeast
developmental maturation GO:0021700 193 0.102
cellular response to organonitrogen compound GO:0071417 145 0.101
axon ensheathment GO:0008366 76 0.101
protein secretion GO:0009306 111 0.100
cell cell recognition GO:0009988 44 0.098
regulation of systemic arterial blood pressure GO:0003073 61 0.095
lipid localization GO:0010876 126 0.094
Worm
peptidyl amino acid modification GO:0018193 336 0.094
vasoconstriction GO:0042310 27 0.093
positive regulation of growth hormone secretion GO:0060124 3 0.093
positive regulation of interferon alpha production GO:0032727 4 0.093
digestive tract development GO:0048565 190 0.092
positive regulation of cytokine production GO:0001819 174 0.091
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.091
Yeast
positive regulation of blood pressure GO:0045777 21 0.090
nitrogen compound transport GO:0071705 271 0.089
regionalization GO:0003002 337 0.088
regulation of blood vessel size GO:0050880 56 0.087
response to organophosphorus GO:0046683 22 0.087
chemotaxis GO:0006935 247 0.086
carbohydrate metabolic process GO:0005975 230 0.085
male anatomical structure morphogenesis GO:0090598 4 0.082
positive regulation of striated muscle contraction GO:0045989 3 0.081
ear development GO:0043583 200 0.081
neurotransmitter transport GO:0006836 76 0.080
multicellular organismal aging GO:0010259 24 0.079
muscle tissue development GO:0060537 308 0.079
aromatic compound catabolic process GO:0019439 286 0.078
Yeast
response to purine containing compound GO:0014074 28 0.078
cellular response to antibiotic GO:0071236 4 0.077
Rat
purine nucleoside triphosphate catabolic process GO:0009146 203 0.076
Yeast
cellular nitrogen compound catabolic process GO:0044270 280 0.075
Yeast
regulation of phosphatase activity GO:0010921 12 0.075
response to oxygen levels GO:0070482 62 0.074
digestive system development GO:0055123 200 0.074
pigmentation GO:0043473 71 0.073
kidney development GO:0001822 213 0.073
purine nucleoside metabolic process GO:0042278 241 0.073
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 199 0.073
Yeast
t cell activation GO:0042110 289 0.072
cellular response to biotic stimulus GO:0071216 92 0.071
regulation of tube size GO:0035150 57 0.071
purine ribonucleotide metabolic process GO:0009150 290 0.070
Yeast
neurotransmitter secretion GO:0007269 62 0.068
peptidyl asparagine modification GO:0018196 1 0.068
regulation of secretion GO:0051046 274 0.068
heart morphogenesis GO:0003007 178 0.068
cell maturation GO:0048469 127 0.068
regulation of cellular catabolic process GO:0031329 242 0.067
positive regulation of hydrolase activity GO:0051345 148 0.067
negative regulation of cellular protein metabolic process GO:0032269 247 0.067
spermatid development GO:0007286 108 0.066
cellular response to lipopolysaccharide GO:0071222 77 0.066
protein n linked glycosylation GO:0006487 12 0.066
positive regulation of secretion by cell GO:1903532 114 0.066
nucleoside phosphate catabolic process GO:1901292 222 0.066
Yeast
amine metabolic process GO:0009308 45 0.065
purine nucleotide catabolic process GO:0006195 211 0.065
Yeast
gland development GO:0048732 330 0.065
response to antibiotic GO:0046677 11 0.065
Rat
regulation of cellular response to oxidative stress GO:1900407 19 0.064
epithelial cell proliferation GO:0050673 174 0.063
establishment of protein localization to endoplasmic reticulum GO:0072599 2 0.063
Yeast
macromolecule glycosylation GO:0043413 55 0.063
regulation of hydrolase activity GO:0051336 246 0.062
nucleoside catabolic process GO:0009164 206 0.061
Yeast
protein targeting to er GO:0045047 2 0.061
Yeast
single organism cell adhesion GO:0098602 156 0.061
cerebellum development GO:0021549 77 0.061
extracellular matrix organization GO:0030198 147 0.061
organic hydroxy compound transport GO:0015850 93 0.060
cation transport GO:0006812 399 0.060
positive regulation of cellular catabolic process GO:0031331 148 0.060
regulation of cell projection organization GO:0031344 206 0.059
regulation of neuron differentiation GO:0045664 281 0.059
anatomical structure homeostasis GO:0060249 145 0.058
ribose phosphate metabolic process GO:0019693 291 0.058
Yeast
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.056
production of molecular mediator of immune response GO:0002440 103 0.056
placenta development GO:0001890 140 0.056
negative regulation of phosphorus metabolic process GO:0010563 184 0.056
regulation of anatomical structure size GO:0090066 178 0.055
heterocycle catabolic process GO:0046700 280 0.055
Yeast
renal system development GO:0072001 225 0.055
mrna metabolic process GO:0016071 84 0.054
cell differentiation involved in salivary gland development GO:0060689 4 0.053
cellular response to molecule of bacterial origin GO:0071219 83 0.053
tissue homeostasis GO:0001894 115 0.052
positive regulation of proteolysis GO:0045862 85 0.052
neuron death GO:0070997 154 0.051
cell activation involved in immune response GO:0002263 126 0.051
cellular response to lipid GO:0071396 145 0.051
purine nucleoside catabolic process GO:0006152 205 0.051
Yeast
multicellular organismal reproductive behavior GO:0033057 23 0.050
mapk cascade GO:0000165 281 0.049
leukocyte differentiation GO:0002521 342 0.049
response to drug GO:0042493 75 0.049
cellular amino acid metabolic process GO:0006520 103 0.048
morphogenesis of embryonic epithelium GO:0016331 159 0.048
camera type eye development GO:0043010 266 0.047
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.047
regulation of epithelial cell proliferation GO:0050678 141 0.047
stress granule disassembly GO:0035617 2 0.047
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.047
positive regulation of insulin secretion GO:0032024 26 0.047
regulation of neuron projection development GO:0010975 169 0.046
regulation of t cell activation GO:0050863 170 0.045
nonmotile primary cilium assembly GO:0035058 8 0.045
cellular protein catabolic process GO:0044257 155 0.044
regulation of translation GO:0006417 71 0.044
cell recognition GO:0008037 83 0.044
response to lipopolysaccharide GO:0032496 128 0.044
regulation of lymphocyte activation GO:0051249 240 0.044
regulation of hepatocyte proliferation GO:2000345 6 0.043
glycosyl compound metabolic process GO:1901657 246 0.043
Yeast
regulation of intracellular transport GO:0032386 159 0.043
epithelial cell differentiation involved in salivary gland development GO:0060690 2 0.042
intracellular protein transport GO:0006886 204 0.042
Yeast
proteasome assembly GO:0043248 1 0.042
epithalamus development GO:0021538 2 0.042
purine nucleoside triphosphate metabolic process GO:0009144 226 0.041
Yeast
positive regulation of dna replication GO:0045740 9 0.041
embryonic organ morphogenesis GO:0048562 276 0.040
cell adhesion GO:0007155 329 0.040
nucleoside phosphate metabolic process GO:0006753 338 0.040
Yeast
response to interleukin 4 GO:0070670 23 0.040
intrinsic apoptotic signaling pathway GO:0097193 132 0.040
vesicle uncoating GO:0072319 4 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
Yeast
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.039
Yeast
urogenital system development GO:0001655 261 0.039
protein import into nucleus GO:0006606 95 0.039
binding of sperm to zona pellucida GO:0007339 34 0.039
positive regulation of secretion GO:0051047 130 0.038
response to temperature stimulus GO:0009266 55 0.038
glycosylation GO:0070085 62 0.038
skeletal system development GO:0001501 356 0.038
response to hypoxia GO:0001666 58 0.038
er associated ubiquitin dependent protein catabolic process GO:0030433 10 0.038
Yeast
cilium morphogenesis GO:0060271 102 0.038
purine ribonucleoside metabolic process GO:0046128 241 0.037
Yeast
positive regulation of protein transport GO:0051222 93 0.037
nucleotide metabolic process GO:0009117 332 0.037
Yeast
multi multicellular organism process GO:0044706 109 0.037
lymphocyte differentiation GO:0030098 242 0.037
regulation of cell activation GO:0050865 289 0.036
neural tube development GO:0021915 160 0.036
meiotic cell cycle GO:0051321 122 0.036
b cell activation GO:0042113 161 0.036
purine containing compound catabolic process GO:0072523 213 0.036
Yeast
pore complex assembly GO:0046931 3 0.036
cellular protein complex assembly GO:0043623 116 0.035
positive regulation of mhc class ii biosynthetic process GO:0045348 4 0.035
cellular component assembly involved in morphogenesis GO:0010927 139 0.035
mitotic cytokinesis GO:0000281 4 0.035
negative regulation of molecular function GO:0044092 258 0.034
cell type specific apoptotic process GO:0097285 268 0.034
myeloid leukocyte differentiation GO:0002573 119 0.034
establishment of protein localization to organelle GO:0072594 118 0.034
Yeast
regulation of purine nucleotide metabolic process GO:1900542 169 0.034
regulation of cell cycle GO:0051726 281 0.034
cytokine secretion GO:0050663 72 0.034
myeloid leukocyte activation GO:0002274 83 0.034
regulation of endopeptidase activity GO:0052548 89 0.033
guanosine containing compound catabolic process GO:1901069 144 0.033
regulation of ion transport GO:0043269 215 0.033
regulation of proteolysis GO:0030162 164 0.033
microtubule cytoskeleton organization GO:0000226 157 0.033
embryonic heart tube morphogenesis GO:0003143 51 0.033
regulation of metal ion transport GO:0010959 106 0.033
microtubule based process GO:0007017 236 0.033
reactive oxygen species metabolic process GO:0072593 84 0.033
endocytosis GO:0006897 168 0.032
regulation of organelle organization GO:0033043 289 0.032
salivary gland development GO:0007431 37 0.032
regulation of lymphocyte differentiation GO:0045619 107 0.032
organelle assembly GO:0070925 177 0.032
endomembrane system organization GO:0010256 147 0.032
striated muscle tissue development GO:0014706 293 0.031
regulation of neurotransmitter levels GO:0001505 87 0.031
response to estrogen GO:0043627 24 0.031
receptor mediated endocytosis GO:0006898 51 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.031
Yeast
ribonucleotide catabolic process GO:0009261 208 0.031
Yeast
peptidyl proline hydroxylation GO:0019511 3 0.031
response to testosterone GO:0033574 3 0.031
regulation of cell adhesion GO:0030155 154 0.030
organism emergence from protective structure GO:0071684 4 0.030
carbohydrate homeostasis GO:0033500 128 0.030
positive regulation of interleukin 6 production GO:0032755 37 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.030
Yeast
hepaticobiliary system development GO:0061008 67 0.030
negative regulation of cytokine production GO:0001818 84 0.030
response to starvation GO:0042594 65 0.030
Human
establishment of organelle localization GO:0051656 122 0.029
response to extracellular stimulus GO:0009991 127 0.029
Human
epithelial cell development GO:0002064 159 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.029
regulation of hormone levels GO:0010817 211 0.029
negative regulation of phosphorylation GO:0042326 166 0.029
response to molecule of bacterial origin GO:0002237 143 0.028
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.028
plasma cell differentiation GO:0002317 3 0.028
hormone secretion GO:0046879 128 0.028
response to nutrient levels GO:0031667 109 0.028
Human
peptide hormone secretion GO:0030072 109 0.028
positive regulation of neuron differentiation GO:0045666 141 0.028
action potential GO:0001508 78 0.028
peptidyl proline hydroxylation to 4 hydroxy l proline GO:0018401 2 0.027
regulation of leukocyte differentiation GO:1902105 159 0.027
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.027
posttranslational protein targeting to membrane GO:0006620 2 0.027
Yeast
ribonucleoprotein complex disassembly GO:0032988 3 0.027
positive regulation of protein secretion GO:0050714 52 0.027
positive regulation of cellular protein catabolic process GO:1903364 34 0.027
photoreceptor cell differentiation GO:0046530 52 0.027
positive regulation of epithelial cell proliferation GO:0050679 68 0.027
hindbrain development GO:0030902 128 0.027
protein localization to membrane GO:0072657 108 0.027
Yeast
innate immune response GO:0045087 157 0.026
amide transport GO:0042886 138 0.026
response to radiation GO:0009314 165 0.026
rna dependent dna replication GO:0006278 3 0.026
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.026
protein hydroxylation GO:0018126 4 0.026
dopaminergic neuron differentiation GO:0071542 14 0.026
nuclear transport GO:0051169 139 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.025
regulation of reactive oxygen species metabolic process GO:2000377 40 0.025
embryonic placenta development GO:0001892 98 0.025
regulation of cell shape GO:0008360 39 0.025
lateral inhibition GO:0046331 1 0.025
response to metal ion GO:0010038 47 0.025
positive regulation of cell projection organization GO:0031346 95 0.025
locomotory behavior GO:0007626 195 0.025
nucleoside monophosphate catabolic process GO:0009125 59 0.025
Yeast
retina development in camera type eye GO:0060041 119 0.025
transmission of nerve impulse GO:0019226 76 0.025
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.024
lymphocyte mediated immunity GO:0002449 139 0.024
hemostasis GO:0007599 78 0.024
protein import into nucleus translocation GO:0000060 12 0.024
4 hydroxyproline metabolic process GO:0019471 5 0.024
positive regulation of cytokine secretion GO:0050715 41 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
Yeast
actin cytoskeleton organization GO:0030036 220 0.024
nucleocytoplasmic transport GO:0006913 139 0.023
establishment of protein localization to membrane GO:0090150 54 0.023
Yeast
cotranslational protein targeting to membrane GO:0006613 2 0.023
Yeast
negative regulation of nervous system development GO:0051961 156 0.023
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.023
regulation of kinase activity GO:0043549 249 0.023
regulation of jun kinase activity GO:0043506 40 0.022
insulin secretion GO:0030073 89 0.022
cellular response to oxidative stress GO:0034599 76 0.022
cellular amine metabolic process GO:0044106 44 0.022
organophosphate catabolic process GO:0046434 232 0.022
Yeast
peptide transport GO:0015833 133 0.022
response to steroid hormone GO:0048545 56 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
second messenger mediated signaling GO:0019932 73 0.022
molting cycle GO:0042303 90 0.022
purine containing compound metabolic process GO:0072521 311 0.022
Yeast
regulation of myeloid leukocyte differentiation GO:0002761 58 0.022
membrane organization GO:0061024 245 0.022
Yeast
cation transmembrane transport GO:0098655 266 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
Yeast
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.021
regulation of production of molecular mediator of immune response GO:0002700 65 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
reactive nitrogen species metabolic process GO:2001057 0 0.021
photoreceptor cell development GO:0042461 40 0.021
lipid biosynthetic process GO:0008610 179 0.021
striated muscle cell development GO:0055002 125 0.021
clathrin mediated endocytosis GO:0072583 7 0.021
dna replication GO:0006260 52 0.021
cardiac muscle tissue development GO:0048738 130 0.021
somitogenesis GO:0001756 69 0.021
wound healing GO:0042060 157 0.020
skeletal myofibril assembly GO:0014866 4 0.020
regulation of cell motility GO:2000145 236 0.020
Human
positive regulation of phospholipase activity GO:0010518 3 0.020
gonad development GO:0008406 141 0.020
regulation of protein kinase activity GO:0045859 232 0.020
immune effector process GO:0002252 321 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
development of primary sexual characteristics GO:0045137 143 0.020
forebrain development GO:0030900 302 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
Yeast
intra golgi vesicle mediated transport GO:0006891 1 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
positive regulation of muscle contraction GO:0045933 10 0.020
histone acetylation GO:0016573 41 0.019
nucleoside metabolic process GO:0009116 246 0.019
Yeast
central nervous system maturation GO:0021626 6 0.019
regulation of fat cell differentiation GO:0045598 81 0.019
cardiac muscle contraction GO:0060048 32 0.019
positive regulation of cell development GO:0010720 237 0.019
cyclic nucleotide metabolic process GO:0009187 59 0.019
multicellular organismal homeostasis GO:0048871 164 0.019
regulation of peptide transport GO:0090087 91 0.019
vesicle localization GO:0051648 86 0.019
central nervous system neuron differentiation GO:0021953 162 0.019
neural tube formation GO:0001841 108 0.018
mitotic cell cycle GO:0000278 195 0.018
regulation of t cell differentiation GO:0045580 83 0.018
response to electrical stimulus GO:0051602 8 0.018
cellular chemical homeostasis GO:0055082 215 0.018
stress activated mapk cascade GO:0051403 80 0.018
regulation of reproductive process GO:2000241 66 0.018
regulation of inflammatory response GO:0050727 147 0.018
t cell differentiation GO:0030217 174 0.018
meiotic nuclear division GO:0007126 115 0.018
regulation of chemotaxis GO:0050920 53 0.018
regulation of dephosphorylation GO:0035303 18 0.018
cognition GO:0050890 149 0.018
cellular response to external stimulus GO:0071496 88 0.018
Human
compound eye development GO:0048749 1 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
nucleotide catabolic process GO:0009166 217 0.018
Yeast
response to inorganic substance GO:0010035 96 0.018
inflammatory response GO:0006954 244 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
leukocyte migration GO:0050900 124 0.018
multicellular organismal signaling GO:0035637 91 0.017
neuron apoptotic process GO:0051402 142 0.017
regulation of homeostatic process GO:0032844 182 0.017
determination of left right symmetry GO:0007368 80 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
Yeast
negative regulation of neuron death GO:1901215 98 0.017
lung development GO:0030324 164 0.017
plasma membrane organization GO:0007009 90 0.017
muscle cell development GO:0055001 133 0.017
tumor necrosis factor production GO:0032640 50 0.017
adult behavior GO:0030534 135 0.017
glucose homeostasis GO:0042593 128 0.017
somite development GO:0061053 81 0.017
regulation of protein catabolic process GO:0042176 108 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.017
positive regulation of t cell differentiation GO:0045582 52 0.017
regulation of body fluid levels GO:0050878 162 0.017
neural precursor cell proliferation GO:0061351 121 0.017
transmembrane transport GO:0055085 412 0.017
Yeast
regulation of action potential GO:0098900 4 0.017
cation homeostasis GO:0055080 212 0.017
negative regulation of cell development GO:0010721 169 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.017
Yeast
hindbrain maturation GO:0021578 6 0.017
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.017
glycoprotein catabolic process GO:0006516 5 0.017
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
peripheral nervous system axon regeneration GO:0014012 2 0.016
positive regulation of transferase activity GO:0051347 167 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.016
Yeast
nuclear import GO:0051170 95 0.016
single organismal cell cell adhesion GO:0016337 131 0.016
blood vessel morphogenesis GO:0048514 285 0.016
limb development GO:0060173 166 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
eye photoreceptor cell differentiation GO:0001754 41 0.016
positive regulation of endocytosis GO:0045807 42 0.016
autophagy GO:0006914 45 0.016
cellular response to toxic substance GO:0097237 7 0.016
Rat
putrescine metabolic process GO:0009445 1 0.016
protein import GO:0017038 101 0.016
positive regulation of protein catabolic process GO:0045732 60 0.016
regulation of mapk cascade GO:0043408 248 0.016
organ growth GO:0035265 117 0.016
calcium mediated signaling GO:0019722 46 0.016
cellular response to extracellular stimulus GO:0031668 81 0.016
Human
vascular process in circulatory system GO:0003018 62 0.016
regulation of binding GO:0051098 111 0.016
neuron projection guidance GO:0097485 141 0.016
respiratory system development GO:0060541 190 0.016
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.016
hatching GO:0035188 4 0.016
cellular response to nutrient levels GO:0031669 64 0.015
Human
positive regulation of immune effector process GO:0002699 107 0.015
asymmetric stem cell division GO:0098722 3 0.015
regulation of response to oxidative stress GO:1902882 19 0.015
eye pigmentation GO:0048069 3 0.015
regulation of canonical wnt signaling pathway GO:0060828 82 0.015
cardiac muscle cell differentiation GO:0055007 69 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
positive regulation of nervous system development GO:0051962 221 0.015
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.015
cerebellar cortex development GO:0021695 48 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.015
regulation of peptidase activity GO:0052547 96 0.015
leukocyte mediated immunity GO:0002443 174 0.015

Hspa5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.037
disease of metabolism DOID:0014667 0 0.033
inherited metabolic disorder DOID:655 0 0.032
immune system cancer DOID:0060083 0 0.025
cancer DOID:162 0 0.025
organ system cancer DOID:0050686 0 0.025
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
immune system disease DOID:2914 0 0.017