Mus musculus

73 known processes

Flt4

FMS-like tyrosine kinase 4

(Aliases: Chy,Flt-4,AI323512,VEGFR-3,VEGFR3)

Flt4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of smooth muscle cell migration GO:0014911 4 0.992
Mouse
single organismal cell cell adhesion GO:0016337 131 0.985
Mouse
glomerulus development GO:0032835 40 0.981
Mouse
endothelial cell differentiation GO:0045446 41 0.977
Mouse
venous blood vessel morphogenesis GO:0048845 7 0.975
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.969
Mouse
regulation of smooth muscle cell migration GO:0014910 6 0.964
Mouse
amine metabolic process GO:0009308 45 0.963
cellular amine metabolic process GO:0044106 44 0.957
endothelium development GO:0003158 45 0.953
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.952
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.950
metanephric glomerulus development GO:0072224 13 0.946
Mouse
female gonad development GO:0008585 71 0.943
Mouse
lung development GO:0030324 164 0.942
Mouse
striated muscle tissue development GO:0014706 293 0.941
Mouse
mesonephric tubule development GO:0072164 94 0.936
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.936
muscle cell differentiation GO:0042692 261 0.935
Mouse
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.934
Human Zebrafish Mouse Rat
kidney development GO:0001822 213 0.929
Mouse
cell matrix adhesion GO:0007160 68 0.928
cardiocyte differentiation GO:0035051 87 0.924
Mouse
renal system vasculature development GO:0061437 15 0.921
Mouse
cellular ketone metabolic process GO:0042180 84 0.915
nephron epithelium morphogenesis GO:0072088 68 0.911
sprouting angiogenesis GO:0002040 26 0.910
development of primary female sexual characteristics GO:0046545 73 0.910
Mouse
metanephric glomerular mesangium development GO:0072223 3 0.907
Mouse
muscle cell development GO:0055001 133 0.905
Mouse
kidney vasculature development GO:0061440 15 0.905
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.905
mesonephros development GO:0001823 97 0.903
peptidyl tyrosine phosphorylation GO:0018108 143 0.902
cell chemotaxis GO:0060326 81 0.900
Mouse
regulation of stem cell proliferation GO:0072091 78 0.897
Mouse
glomerular mesangial cell differentiation GO:0072008 3 0.896
epithelial tube morphogenesis GO:0060562 303 0.894
Mouse Fly
nephron development GO:0072006 109 0.885
Mouse
venous blood vessel development GO:0060841 13 0.885
Zebrafish
myeloid cell differentiation GO:0030099 233 0.883
Mouse
peptidyl tyrosine modification GO:0018212 145 0.879
positive regulation of dna biosynthetic process GO:2000573 4 0.877
Mouse
nephron tubule morphogenesis GO:0072078 68 0.877
endothelial cell migration GO:0043542 44 0.876
Human Zebrafish Mouse
single organism cell adhesion GO:0098602 156 0.871
Mouse
glomerular mesangial cell development GO:0072144 3 0.865
renal system development GO:0072001 225 0.862
Mouse Fly
cell proliferation involved in kidney development GO:0072111 14 0.858
Mouse
ovulation cycle GO:0042698 59 0.857
Mouse
tissue migration GO:0090130 68 0.854
Human Zebrafish Mouse Fly
regulation of endothelial cell differentiation GO:0045601 10 0.851
Mouse
response to growth factor GO:0070848 198 0.846
cardiac cell development GO:0055006 41 0.844
Mouse
muscle tissue development GO:0060537 308 0.843
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.837
ureteric bud development GO:0001657 94 0.837
cardiac muscle tissue development GO:0048738 130 0.836
Mouse
substrate dependent cell migration GO:0006929 18 0.835
cell substrate adhesion GO:0031589 130 0.829
stem cell proliferation GO:0072089 117 0.827
Mouse
glomerulus vasculature development GO:0072012 14 0.821
Mouse
branching involved in salivary gland morphogenesis GO:0060445 26 0.816
regulation of vasculature development GO:1901342 88 0.816
Mouse
positive regulation of cell migration GO:0030335 109 0.812
Human Mouse
respiratory tube development GO:0030323 167 0.810
Mouse
ureteric bud morphogenesis GO:0060675 62 0.808
urogenital system development GO:0001655 261 0.805
Mouse Fly
positive regulation of kidney development GO:0090184 28 0.795
Mouse
mesonephric epithelium development GO:0072163 94 0.783
cell proliferation involved in metanephros development GO:0072203 9 0.782
Mouse
cardiac muscle tissue growth GO:0055017 37 0.781
cellular amino acid metabolic process GO:0006520 103 0.780
salivary gland morphogenesis GO:0007435 33 0.779
Fly
coronary vasculature development GO:0060976 12 0.769
Mouse
neuron projection guidance GO:0097485 141 0.769
regulation of cell substrate adhesion GO:0010810 73 0.764
cell adhesion GO:0007155 329 0.761
Mouse
cardiac muscle fiber development GO:0048739 4 0.759
regulation of cell migration GO:0030334 219 0.757
Human Mouse
multicellular organismal homeostasis GO:0048871 164 0.740
Mouse
mesonephric tubule morphogenesis GO:0072171 63 0.727
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.726
Mouse
gland development GO:0048732 330 0.725
Mouse Fly
positive regulation of angiogenesis GO:0045766 46 0.720
Mouse
lung alveolus development GO:0048286 45 0.720
Mouse
morphogenesis of a branching structure GO:0001763 203 0.717
Mouse
axonogenesis GO:0007409 274 0.714
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.714
Mouse
vegf activated neuropilin signaling pathway GO:0038190 2 0.712
nephron morphogenesis GO:0072028 69 0.711
positive regulation of mitotic cell cycle GO:0045931 41 0.706
Mouse
protein o linked glycosylation GO:0006493 16 0.705
regulation of cell motility GO:2000145 236 0.698
Human Mouse
metanephric glomerular endothelium development GO:0072264 1 0.692
mesangial cell differentiation GO:0072007 4 0.687
epithelium migration GO:0090132 63 0.686
Human Zebrafish Mouse Fly
regulation of mesenchymal cell proliferation GO:0010464 37 0.683
Mouse
ameboidal type cell migration GO:0001667 128 0.681
Human Zebrafish Mouse Fly
inositol lipid mediated signaling GO:0048017 41 0.681
Mouse
positive regulation of mitotic cell cycle embryonic GO:0045977 2 0.678
positive regulation of mapk cascade GO:0043410 170 0.675
Human Mouse Fly
branching involved in ureteric bud morphogenesis GO:0001658 56 0.662
kidney morphogenesis GO:0060993 83 0.661
renal tubule morphogenesis GO:0061333 72 0.661
Fly
regulation of vasculogenesis GO:2001212 9 0.659
Mouse
positive regulation of cell motility GO:2000147 116 0.659
Human Mouse
retinal ganglion cell axon guidance GO:0031290 18 0.658
morphogenesis of a branching epithelium GO:0061138 193 0.657
Mouse
angiogenesis GO:0001525 201 0.651
epithelial cell proliferation GO:0050673 174 0.647
Human Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.647
Mouse
positive regulation of protein modification process GO:0031401 299 0.642
Human Mouse
regulation of erk1 and erk2 cascade GO:0070372 71 0.640
Human Mouse
erythrocyte differentiation GO:0030218 88 0.639
Mouse
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.638
extracellular matrix organization GO:0030198 147 0.629
Mouse
regulation of cell adhesion GO:0030155 154 0.627
blood vessel endothelial cell migration GO:0043534 23 0.627
Zebrafish Mouse
striated muscle cell development GO:0055002 125 0.617
Mouse
cellular response to vascular endothelial growth factor stimulus GO:0035924 11 0.616
epithelial cell differentiation involved in kidney development GO:0035850 23 0.615
embryonic organ morphogenesis GO:0048562 276 0.615
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.611
Human Mouse
phospholipid metabolic process GO:0006644 87 0.609
Mouse
commissural neuron axon guidance GO:0071679 8 0.609
cellular response to growth factor stimulus GO:0071363 197 0.606
ovarian follicle development GO:0001541 40 0.595
Mouse
eye photoreceptor cell differentiation GO:0001754 41 0.581
melanocyte migration GO:0097324 2 0.579
Mouse
regulation of kidney development GO:0090183 40 0.577
Mouse
exocrine system development GO:0035272 45 0.576
Fly
neuropilin signaling pathway GO:0038189 2 0.572
heart morphogenesis GO:0003007 178 0.567
rac protein signal transduction GO:0016601 13 0.557
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.553
Mouse
regulation of endothelial cell proliferation GO:0001936 23 0.553
Human
muscle cell proliferation GO:0033002 52 0.553
Mouse
positive regulation of cell substrate adhesion GO:0010811 47 0.550
mesenchymal cell proliferation GO:0010463 44 0.547
Mouse
artery development GO:0060840 53 0.546
Mouse
regulation of cell cycle GO:0051726 281 0.545
Mouse
renal tubule development GO:0061326 87 0.536
Fly
metanephric mesenchymal cell migration GO:0035789 2 0.534
Mouse
axon guidance GO:0007411 141 0.529
metanephros development GO:0001656 79 0.524
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.522
endothelial cell proliferation GO:0001935 27 0.520
Human
glomerular capillary formation GO:0072104 6 0.520
Mouse
sphingolipid metabolic process GO:0006665 45 0.518
Mouse
regulation of body fluid levels GO:0050878 162 0.517
sensory organ morphogenesis GO:0090596 242 0.516
rhythmic process GO:0048511 174 0.510
Mouse
vascular process in circulatory system GO:0003018 62 0.508
steroid metabolic process GO:0008202 119 0.502
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.502
Mouse
chemotaxis GO:0006935 247 0.497
Mouse
heart trabecula morphogenesis GO:0061384 26 0.494
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.490
vascular smooth muscle cell differentiation GO:0035886 11 0.483
connective tissue development GO:0061448 179 0.481
Mouse
glomerular endothelium development GO:0072011 2 0.481
positive regulation of cell development GO:0010720 237 0.480
development of primary sexual characteristics GO:0045137 143 0.479
Mouse
regulation of endothelial cell migration GO:0010594 22 0.477
Human
neuroepithelial cell differentiation GO:0060563 37 0.477
Mouse
osteoclast differentiation GO:0030316 62 0.476
Mouse
dendritic cell cytokine production GO:0002371 3 0.476
Mouse
developmental maturation GO:0021700 193 0.474
Mouse
regulation of organ morphogenesis GO:2000027 144 0.470
muscle system process GO:0003012 141 0.469
glycerolipid metabolic process GO:0046486 122 0.467
Mouse
organelle assembly GO:0070925 177 0.464
Mouse
pro t cell differentiation GO:0002572 3 0.464
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.461
Mouse
leukocyte proliferation GO:0070661 172 0.461
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.458
heart trabecula formation GO:0060347 14 0.458
cellular response to erythropoietin GO:0036018 1 0.456
Mouse
response to macrophage colony stimulating factor GO:0036005 3 0.456
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.455
leukocyte differentiation GO:0002521 342 0.453
Mouse
anatomical structure homeostasis GO:0060249 145 0.451
Mouse
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.448
Mouse
immature b cell differentiation GO:0002327 10 0.448
Mouse
homeostasis of number of cells GO:0048872 210 0.439
Mouse Fly
leukocyte migration GO:0050900 124 0.437
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.436
Mouse
glycerophospholipid metabolic process GO:0006650 71 0.434
Mouse
salivary gland development GO:0007431 37 0.432
Fly
positive regulation of epithelial cell proliferation GO:0050679 68 0.429
Human Mouse
regulation of cell projection organization GO:0031344 206 0.428
positive regulation of neural precursor cell proliferation GO:2000179 42 0.427
regulation of system process GO:0044057 200 0.424
positive regulation of cytokine production GO:0001819 174 0.424
Human
cellular response to organonitrogen compound GO:0071417 145 0.423
Mouse Fly
blood vessel morphogenesis GO:0048514 285 0.422
muscle cell migration GO:0014812 19 0.418
Mouse
negative regulation of cell migration GO:0030336 59 0.417
cell maturation GO:0048469 127 0.410
Mouse
cell migration involved in coronary angiogenesis GO:0060981 1 0.406
Mouse
positive chemotaxis GO:0050918 18 0.404
positive regulation of lymphangiogenesis GO:1901492 3 0.402
cell fate commitment GO:0045165 210 0.401
Mouse
gonad development GO:0008406 141 0.401
Mouse
response to erythropoietin GO:0036017 1 0.399
Mouse
metanephric glomerulus vasculature morphogenesis GO:0072276 3 0.398
Mouse
cell type specific apoptotic process GO:0097285 268 0.397
outflow tract morphogenesis GO:0003151 53 0.397
cardiac atrium development GO:0003230 24 0.397
circulatory system process GO:0003013 197 0.396
positive regulation of neuron differentiation GO:0045666 141 0.395
blood circulation GO:0008015 195 0.394
macromolecule glycosylation GO:0043413 55 0.393
cation homeostasis GO:0055080 212 0.389
Mouse
regulation of angiogenesis GO:0045765 81 0.386
Mouse
positive regulation of cell adhesion GO:0045785 80 0.386
aorta morphogenesis GO:0035909 22 0.380
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.377
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.375
regulation of bmp signaling pathway GO:0030510 60 0.371
Mouse
cardiac atrium morphogenesis GO:0003209 23 0.361
cellular homeostasis GO:0019725 240 0.361
kidney epithelium development GO:0072073 121 0.360
t cell activation GO:0042110 289 0.359
Mouse
neuron apoptotic process GO:0051402 142 0.359
regulation of apoptotic signaling pathway GO:2001233 197 0.354
mesangial cell development GO:0072143 4 0.353
cellular response to insulin stimulus GO:0032869 78 0.353
Fly
nephron epithelium development GO:0072009 92 0.350
mapk cascade GO:0000165 281 0.350
Human Mouse Fly
metanephric mesangial cell differentiation GO:0072209 1 0.349
organ growth GO:0035265 117 0.347
cardiac muscle cell differentiation GO:0055007 69 0.343
Mouse
cellular response to stem cell factor stimulus GO:0036216 3 0.343
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.342
Mouse
positive regulation of endothelial cell proliferation GO:0001938 17 0.340
Human
phosphatidylinositol metabolic process GO:0046488 45 0.336
Mouse
cell junction organization GO:0034330 77 0.328
positive regulation of mesonephros development GO:0061213 20 0.328
embryonic hemopoiesis GO:0035162 23 0.327
Mouse Fly
post embryonic camera type eye development GO:0031077 8 0.322
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.321
epithelial cell migration GO:0010631 63 0.320
Human Zebrafish Mouse Fly
cardiac muscle cell development GO:0055013 39 0.320
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.319
Mouse
apoptotic signaling pathway GO:0097190 306 0.315
heart growth GO:0060419 45 0.314
glycoprotein biosynthetic process GO:0009101 89 0.314
mammary gland lobule development GO:0061377 22 0.310
positive regulation of chemotaxis GO:0050921 38 0.309
Mouse
protein glycosylation GO:0006486 55 0.308
endothelial cell apoptotic process GO:0072577 9 0.306
regulation of positive chemotaxis GO:0050926 7 0.305
cell cell junction organization GO:0045216 72 0.305
regulation of axon guidance GO:1902667 13 0.304
positive regulation of axon extension GO:0045773 20 0.302
spermatogenesis GO:0007283 284 0.301
Mouse
metanephric nephron development GO:0072210 34 0.301
Mouse
coronary artery morphogenesis GO:0060982 6 0.300
blood vessel remodeling GO:0001974 33 0.298
smooth muscle tissue development GO:0048745 22 0.297
Mouse
melanocyte adhesion GO:0097326 1 0.297
Mouse
skeletal system morphogenesis GO:0048705 203 0.296
Mouse
myeloid leukocyte migration GO:0097529 57 0.296
female sex differentiation GO:0046660 84 0.294
Mouse
regulation of axon extension GO:0030516 43 0.294
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.288
calcium mediated signaling using intracellular calcium source GO:0035584 3 0.287
ion transmembrane transport GO:0034220 361 0.286
Mouse
positive regulation of calcium ion transport GO:0051928 27 0.284
Mouse
embryonic heart tube development GO:0035050 65 0.281
positive regulation of neuroblast proliferation GO:0002052 19 0.281
respiratory system development GO:0060541 190 0.278
Mouse
epithelial cell development GO:0002064 159 0.275
Fly
cellular response to x ray GO:0071481 2 0.273
negative regulation of cell adhesion GO:0007162 45 0.272
regulation of branching involved in salivary gland morphogenesis GO:0060693 11 0.271
negative regulation of endothelial cell apoptotic process GO:2000352 7 0.270
regulation of mapk cascade GO:0043408 248 0.269
Human Mouse Fly
leukocyte homeostasis GO:0001776 79 0.266
Mouse
response to fibroblast growth factor GO:0071774 47 0.265
positive regulation of neuron projection development GO:0010976 79 0.265
eye photoreceptor cell development GO:0042462 31 0.264
regulation of protein kinase activity GO:0045859 232 0.264
Mouse
inflammatory response GO:0006954 244 0.262
Mouse
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.262
regulation of cytoskeleton organization GO:0051493 122 0.260
Mouse
cell differentiation involved in kidney development GO:0061005 33 0.258
regulation of hormone levels GO:0010817 211 0.257
Mouse
regulation of transferase activity GO:0051338 263 0.256
Mouse
regulation of cell growth GO:0001558 91 0.256
Rat
innate immune response GO:0045087 157 0.255
Fly
regulation of neural precursor cell proliferation GO:2000177 70 0.254
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.252
Mouse
negative regulation of cell motility GO:2000146 61 0.252
extrinsic apoptotic signaling pathway GO:0097191 126 0.252
cardiac vascular smooth muscle cell development GO:0060948 3 0.250
lung vasculature development GO:0060426 7 0.250
glomerular epithelium development GO:0072010 11 0.248
response to x ray GO:0010165 11 0.246
tissue homeostasis GO:0001894 115 0.246
Mouse
primitive erythrocyte differentiation GO:0060319 3 0.245
positive regulation of nervous system development GO:0051962 221 0.244
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.244
Human Mouse
regulation of cell size GO:0008361 72 0.239
positive regulation of transferase activity GO:0051347 167 0.236
Mouse
regulation of organelle organization GO:0033043 289 0.234
Mouse
regulation of blood vessel endothelial cell migration GO:0043535 12 0.234
regulation of epithelial cell proliferation GO:0050678 141 0.233
Human Mouse
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.232
Mouse
cell migration involved in vasculogenesis GO:0035441 2 0.232
Mouse
embryonic placenta development GO:0001892 98 0.232
regulation of cell shape GO:0008360 39 0.229
Mouse Fly
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.229
Mouse
ventricular septum development GO:0003281 42 0.229
glucose homeostasis GO:0042593 128 0.229
peptidyl amino acid modification GO:0018193 336 0.228
regulation of cell division GO:0051302 76 0.227
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.226
Mouse Fly
adherens junction assembly GO:0034333 22 0.226
negative regulation of lymphocyte activation GO:0051250 91 0.225
Mouse
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.223
glycosylation GO:0070085 62 0.223
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.219
Mouse
regulation of kinase activity GO:0043549 249 0.219
Mouse
response to ionizing radiation GO:0010212 42 0.216
renal system process GO:0003014 48 0.214
cytokine production GO:0001816 319 0.214
Human Mouse
regulation of epithelial cell migration GO:0010632 35 0.211
Human
cell migration involved in kidney development GO:0035787 3 0.211
Mouse
regulation of retinal ganglion cell axon guidance GO:0090259 2 0.210
regulation of branching involved in salivary gland morphogenesis by epithelial mesenchymal signaling GO:0060683 1 0.209
negative regulation of leukocyte differentiation GO:1902106 51 0.208
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.206
Mouse
leukocyte chemotaxis GO:0030595 69 0.205
central nervous system neuron development GO:0021954 67 0.204
regulation of peptidyl serine phosphorylation GO:0033135 39 0.203
palate development GO:0060021 76 0.202
Mouse
regulation of lipid metabolic process GO:0019216 118 0.200
positive regulation of glomerular filtration GO:0003104 1 0.199
cell substrate junction assembly GO:0007044 24 0.198
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.198
Mouse
regulation of hippo signaling GO:0035330 1 0.198
regulation of organ growth GO:0046620 61 0.196
regulation of mesonephros development GO:0061217 24 0.195
metanephric glomerular epithelium development GO:0072244 3 0.193
phosphatidylinositol mediated signaling GO:0048015 41 0.193
Mouse
germ cell development GO:0007281 185 0.191
Mouse Fly
male gamete generation GO:0048232 285 0.189
Mouse
mesoderm morphogenesis GO:0048332 64 0.188
regulation of cell activation GO:0050865 289 0.185
Mouse
metanephric glomerulus morphogenesis GO:0072275 3 0.185
Mouse
ventricular trabecula myocardium morphogenesis GO:0003222 11 0.184
positive regulation of cell cycle GO:0045787 92 0.182
Mouse
dna biosynthetic process GO:0071897 22 0.181
Mouse
membrane lipid metabolic process GO:0006643 53 0.180
Mouse
neural precursor cell proliferation GO:0061351 121 0.180
mesoderm development GO:0007498 100 0.180
positive regulation of organelle organization GO:0010638 128 0.179
Mouse
nephron tubule development GO:0072080 84 0.178
odontogenesis GO:0042476 78 0.177
Mouse
cellular response to peptide GO:1901653 92 0.176
Fly
endothelial cell development GO:0001885 20 0.176
regulation of cellular component biogenesis GO:0044087 181 0.175
heart contraction GO:0060047 93 0.174
muscle fiber development GO:0048747 76 0.173
regulation of neuron apoptotic process GO:0043523 122 0.172
actomyosin structure organization GO:0031032 56 0.171
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.170
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.170
Mouse
cellular response to monosaccharide stimulus GO:0071326 47 0.169
b cell activation GO:0042113 161 0.168
Mouse
wound healing GO:0042060 157 0.167
Mouse
cation transport GO:0006812 399 0.166
Mouse
regulation of calcium ion transport GO:0051924 69 0.166
Mouse
locomotory behavior GO:0007626 195 0.166
forebrain development GO:0030900 302 0.165
stem cell differentiation GO:0048863 268 0.161
Mouse
cell junction assembly GO:0034329 52 0.160
cardiac ventricle morphogenesis GO:0003208 50 0.157
organelle fission GO:0048285 170 0.157
Mouse
cell migration involved in metanephros development GO:0035788 2 0.157
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.156
Mouse
angiogenesis involved in coronary vascular morphogenesis GO:0060978 2 0.156
Mouse
muscle contraction GO:0006936 101 0.156
cellular response to peptide hormone stimulus GO:0071375 92 0.155
Fly
cell adhesion mediated by integrin GO:0033627 18 0.152
regulation of lymphangiogenesis GO:1901490 3 0.151
metanephric epithelium development GO:0072207 21 0.150
vascular endothelial growth factor signaling pathway GO:0038084 10 0.150
lymphocyte differentiation GO:0030098 242 0.149
Mouse
digestive tract morphogenesis GO:0048546 147 0.148
Mouse Fly
regulation of mitotic cell cycle GO:0007346 126 0.147
Mouse
liposaccharide metabolic process GO:1903509 27 0.147
Mouse
calcium ion transport GO:0006816 159 0.145
Mouse
endocrine system development GO:0035270 98 0.145
Mouse
positive regulation of retinal ganglion cell axon guidance GO:1902336 2 0.145
actin cytoskeleton reorganization GO:0031532 21 0.145
Mouse
regionalization GO:0003002 337 0.144
neuron projection extension GO:1990138 64 0.144
peptidyl serine phosphorylation GO:0018105 74 0.143
digestive tract development GO:0048565 190 0.142
Mouse Fly
camera type eye development GO:0043010 266 0.140
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.136
Mouse
glycolipid metabolic process GO:0006664 25 0.136
Mouse
cellular response to ionizing radiation GO:0071479 11 0.136
positive regulation of positive chemotaxis GO:0050927 7 0.135
metanephric nephron epithelium development GO:0072243 19 0.134
regulation of developmental pigmentation GO:0048070 14 0.134
Mouse
detection of stimulus GO:0051606 84 0.132
Mouse
cellular response to radiation GO:0071478 28 0.132
photoreceptor cell differentiation GO:0046530 52 0.131
negative regulation of cell proliferation GO:0008285 296 0.131
Mouse
blastocyst development GO:0001824 80 0.130
small gtpase mediated signal transduction GO:0007264 97 0.130
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.130
neuron death GO:0070997 154 0.129
sensory perception GO:0007600 245 0.128
Mouse
renal interstitial fibroblast development GO:0072141 5 0.128
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.128
negative regulation of phosphorus metabolic process GO:0010563 184 0.128
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.127
Mouse
mitral valve morphogenesis GO:0003183 4 0.126
ectopic germ cell programmed cell death GO:0035234 9 0.126
Mouse
regulation of fibroblast growth factor production GO:0090270 4 0.126
regulation of nuclear division GO:0051783 56 0.125
Mouse
axon extension involved in axon guidance GO:0048846 14 0.125
glomerular mesangium development GO:0072109 5 0.124
Mouse
cellular response to hexose stimulus GO:0071331 47 0.124
regulation of gliogenesis GO:0014013 50 0.123
epithelial cell cell adhesion GO:0090136 6 0.122
Mouse
glomerular mesangial cell proliferation GO:0072110 3 0.122
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.121
regulation of metal ion transport GO:0010959 106 0.120
Mouse
negative regulation of endothelial cell migration GO:0010596 4 0.120
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.119
Mouse
response to acid chemical GO:0001101 111 0.119
Mouse
cardiac muscle contraction GO:0060048 32 0.118
lymph vessel morphogenesis GO:0036303 11 0.118
regulation of morphogenesis of a branching structure GO:0060688 53 0.118
dopaminergic neuron differentiation GO:0071542 14 0.118
mammary gland alveolus development GO:0060749 22 0.117
regulation of lymphocyte activation GO:0051249 240 0.116
Mouse
endodermal cell fate specification GO:0001714 4 0.116
ruffle organization GO:0031529 16 0.116
Mouse
metanephric glomerular capillary formation GO:0072277 3 0.115
Mouse
positive regulation of protein kinase b signaling GO:0051897 32 0.115
regulation of glomerular filtration GO:0003093 3 0.115
cellular chemical homeostasis GO:0055082 215 0.115
cellular response to dna damage stimulus GO:0006974 207 0.113
Fly
aromatic compound catabolic process GO:0019439 286 0.111
regulation of hydrolase activity GO:0051336 246 0.110
megakaryocyte differentiation GO:0030219 26 0.110
Mouse
pro b cell differentiation GO:0002328 10 0.109
Mouse
cellular response to carbohydrate stimulus GO:0071322 50 0.108
negative regulation of neuron apoptotic process GO:0043524 92 0.108
humoral immune response GO:0006959 57 0.108
Fly
cell migration involved in endocardial cushion formation GO:0003273 3 0.108
regulation of ras protein signal transduction GO:0046578 114 0.107
mesenchyme morphogenesis GO:0072132 32 0.107
immune effector process GO:0002252 321 0.107
Mouse
transmembrane transport GO:0055085 412 0.107
Mouse
renal system process involved in regulation of blood volume GO:0001977 4 0.104
positive regulation of stem cell proliferation GO:2000648 59 0.104
Mouse
kidney interstitial fibroblast differentiation GO:0072071 5 0.103
positive regulation of cellular component biogenesis GO:0044089 94 0.103
aminoglycan metabolic process GO:0006022 34 0.103
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.103
Mouse
neuron migration GO:0001764 122 0.102
epidermis development GO:0008544 187 0.100
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.099
Mouse
positive regulation of endothelial cell migration GO:0010595 12 0.099
Human
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.098
regulation of rho gtpase activity GO:0032319 58 0.098
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.097
rho protein signal transduction GO:0007266 32 0.097
glomerular filtration GO:0003094 7 0.097
focal adhesion assembly GO:0048041 19 0.096
brain morphogenesis GO:0048854 32 0.096
regulation of leukocyte differentiation GO:1902105 159 0.096
Mouse
embryonic digestive tract development GO:0048566 27 0.096
Mouse
epithelial mesenchymal cell signaling GO:0060684 7 0.094
response to peptide hormone GO:0043434 127 0.094
Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.093
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.093
cell recognition GO:0008037 83 0.093
sensory perception of mechanical stimulus GO:0050954 107 0.092
Mouse
pericardium development GO:0060039 16 0.092
cell differentiation involved in metanephros development GO:0072202 12 0.091
erk1 and erk2 cascade GO:0070371 77 0.090
Human Mouse
regulation of neuron death GO:1901214 134 0.090
carbohydrate derivative biosynthetic process GO:1901137 183 0.089
central nervous system projection neuron axonogenesis GO:0021952 21 0.089
regulation of chemotaxis GO:0050920 53 0.089
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.088
Mouse

Flt4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.154
Human
disease of anatomical entity DOID:7 0 0.154
Human
lymphatic system disease DOID:75 0 0.106
Human