Mus musculus

105 known processes

Flt1

FMS-like tyrosine kinase 1

(Aliases: VEGFR1,Flt-1,AI323757,sFlt1,VEGFR-1)

Flt1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of protein kinase activity GO:0045859 232 0.898
Human Mouse Rat
positive regulation of neuron projection development GO:0010976 79 0.896
epithelial cell migration GO:0010631 63 0.892
Mouse Fly
glycerophospholipid metabolic process GO:0006650 71 0.884
Human Mouse
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.881
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.869
tissue migration GO:0090130 68 0.852
Mouse Fly
cellular amino acid metabolic process GO:0006520 103 0.852
vegf activated neuropilin signaling pathway GO:0038190 2 0.826
regulation of chemotaxis GO:0050920 53 0.822
Mouse
detection of external stimulus GO:0009581 61 0.818
Mouse
t cell receptor signaling pathway GO:0050852 46 0.815
regulation of cellular amine metabolic process GO:0033238 20 0.815
trunk neural crest cell migration GO:0036484 4 0.811
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.804
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.799
peptidyl tyrosine phosphorylation GO:0018108 143 0.796
axonogenesis GO:0007409 274 0.792
epithelium migration GO:0090132 63 0.786
Mouse Fly
regulation of vasculature development GO:1901342 88 0.783
Human Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.776
g protein coupled receptor signaling pathway GO:0007186 243 0.775
positive regulation of smooth muscle cell migration GO:0014911 4 0.766
Mouse
sympathetic neuron projection extension GO:0097490 4 0.754
urogenital system development GO:0001655 261 0.751
Mouse Fly
regulation of cell projection organization GO:0031344 206 0.740
regulation of cellular ketone metabolic process GO:0010565 66 0.733
positive regulation of cell development GO:0010720 237 0.730
cation transport GO:0006812 399 0.722
Mouse
kidney development GO:0001822 213 0.719
Mouse
blood vessel morphogenesis GO:0048514 285 0.710
amine metabolic process GO:0009308 45 0.705
regulation of smooth muscle cell migration GO:0014910 6 0.700
Mouse
regulation of hormone levels GO:0010817 211 0.696
Mouse
cellular ketone metabolic process GO:0042180 84 0.684
gland development GO:0048732 330 0.680
Mouse Fly
positive regulation of creb transcription factor activity GO:0032793 4 0.679
heart contraction GO:0060047 93 0.678
Zebrafish
response to organonitrogen compound GO:0010243 246 0.667
Mouse Fly
epithelial tube morphogenesis GO:0060562 303 0.662
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.657
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.649
sympathetic neuron projection guidance GO:0097491 4 0.645
regulation of angiogenesis GO:0045765 81 0.643
Human Mouse
telencephalon development GO:0021537 186 0.640
pigment cell differentiation GO:0050931 27 0.638
Mouse
camera type eye development GO:0043010 266 0.634
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.621
developmental maturation GO:0021700 193 0.612
Mouse
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.601
Mouse
regulation of neuron differentiation GO:0045664 281 0.600
ventral trunk neural crest cell migration GO:0036486 4 0.599
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.597
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.575
Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.575
transmembrane transport GO:0055085 412 0.573
Mouse
anion transport GO:0006820 177 0.564
cerebral cortex development GO:0021987 86 0.563
positive regulation of mapk cascade GO:0043410 170 0.562
Human Mouse Rat Fly
positive regulation of cell projection organization GO:0031346 95 0.554
response to peptide GO:1901652 136 0.547
Fly
neuropilin signaling pathway GO:0038189 2 0.545
sterol transmembrane transport GO:0035382 2 0.541
inositol lipid mediated signaling GO:0048017 41 0.539
Human Mouse
circulatory system process GO:0003013 197 0.538
Zebrafish
heart process GO:0003015 94 0.536
Zebrafish
cerebral cortex cell migration GO:0021795 44 0.534
forebrain development GO:0030900 302 0.533
branching involved in salivary gland morphogenesis GO:0060445 26 0.525
regulation of rho gtpase activity GO:0032319 58 0.517
smooth muscle cell chemotaxis GO:0071670 2 0.515
Mouse
telencephalon cell migration GO:0022029 55 0.514
branchiomotor neuron axon guidance GO:0021785 7 0.512
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.511
regulation of cellular amino acid metabolic process GO:0006521 5 0.509
organonitrogen compound catabolic process GO:1901565 264 0.506
cell chemotaxis GO:0060326 81 0.506
Human Mouse
pallium development GO:0021543 120 0.505
ameboidal type cell migration GO:0001667 128 0.502
Mouse Fly
metal ion homeostasis GO:0055065 189 0.500
Mouse
regulation of cell migration GO:0030334 219 0.498
Human Mouse Rat
cellular response to organonitrogen compound GO:0071417 145 0.496
Mouse Fly
blood vessel endothelial cell migration GO:0043534 23 0.495
Mouse
facioacoustic ganglion development GO:1903375 3 0.495
regulation of cellular catabolic process GO:0031329 242 0.494
dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 5 0.493
positive regulation of chemotaxis GO:0050921 38 0.491
Mouse
angiogenesis GO:0001525 201 0.487
small gtpase mediated signal transduction GO:0007264 97 0.485
purine ribonucleotide metabolic process GO:0009150 290 0.484
sprouting angiogenesis GO:0002040 26 0.484
organophosphate catabolic process GO:0046434 232 0.475
ion transmembrane transport GO:0034220 361 0.471
Mouse
regulation of transmembrane transport GO:0034762 128 0.470
Mouse
vascular endothelial growth factor signaling pathway GO:0038084 10 0.470
negative regulation of cell proliferation GO:0008285 296 0.469
Mouse
synaptic transmission GO:0007268 329 0.467
respiratory system development GO:0060541 190 0.467
Mouse
endothelial cell migration GO:0043542 44 0.466
Mouse
cellular amine metabolic process GO:0044106 44 0.461
inorganic ion transmembrane transport GO:0098660 234 0.455
response to radiation GO:0009314 165 0.454
Mouse
regulation of cell growth GO:0001558 91 0.452
regulation of body fluid levels GO:0050878 162 0.447
cellular ion homeostasis GO:0006873 165 0.446
purine nucleotide metabolic process GO:0006163 302 0.445
myeloid cell differentiation GO:0030099 233 0.445
Mouse
chemical homeostasis within a tissue GO:0048875 9 0.440
Mouse
hypothalamus gonadotrophin releasing hormone neuron differentiation GO:0021886 4 0.437
metanephric glomerular mesangium development GO:0072223 3 0.435
Mouse
cellular homeostasis GO:0019725 240 0.434
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.433
Human Mouse
renal system development GO:0072001 225 0.430
Mouse Fly
cellular response to vascular endothelial growth factor stimulus GO:0035924 11 0.430
blood circulation GO:0008015 195 0.426
Zebrafish
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.424
Mouse
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.418
Mouse
eye photoreceptor cell differentiation GO:0001754 41 0.415
leukocyte chemotaxis GO:0030595 69 0.414
Human
branching morphogenesis of an epithelial tube GO:0048754 159 0.413
positive regulation of angiogenesis GO:0045766 46 0.405
Human Mouse
muscle contraction GO:0006936 101 0.402
Rat
sensory organ morphogenesis GO:0090596 242 0.398
regulation of cell motility GO:2000145 236 0.397
Human Mouse Rat
phosphatidylinositol mediated signaling GO:0048015 41 0.392
Human Mouse
regulation of endothelial cell migration GO:0010594 22 0.389
skeletal muscle fiber development GO:0048741 58 0.389
retina morphogenesis in camera type eye GO:0060042 45 0.385
antigen receptor mediated signaling pathway GO:0050851 64 0.381
positive regulation of neuron differentiation GO:0045666 141 0.381
lung development GO:0030324 164 0.376
Mouse
regulation of ion transport GO:0043269 215 0.375
Mouse
immune response activating signal transduction GO:0002757 116 0.373
peptidyl amino acid modification GO:0018193 336 0.372
carbohydrate metabolic process GO:0005975 230 0.371
vegf activated neuropilin signaling pathway involved in axon guidance GO:1902378 1 0.367
positive regulation of epithelial cell migration GO:0010634 19 0.365
regulation of transferase activity GO:0051338 263 0.362
Human Mouse Rat
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.361
Mouse
single organismal cell cell adhesion GO:0016337 131 0.361
Mouse
vascular process in circulatory system GO:0003018 62 0.360
positive regulation of cell migration GO:0030335 109 0.358
Human Mouse Rat
response to hypoxia GO:0001666 58 0.358
positive regulation of cell motility GO:2000147 116 0.358
Human Mouse Rat
skeletal system development GO:0001501 356 0.352
Mouse
positive regulation of nervous system development GO:0051962 221 0.352
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.348
striated muscle tissue development GO:0014706 293 0.347
Mouse
trigeminal nerve morphogenesis GO:0021636 6 0.343
muscle fiber development GO:0048747 76 0.341
limbic system development GO:0021761 72 0.340
cellular response to erythropoietin GO:0036018 1 0.340
Mouse
muscle cell differentiation GO:0042692 261 0.339
Mouse
cell adhesion GO:0007155 329 0.338
Mouse
endothelial cell differentiation GO:0045446 41 0.337
Mouse
chemotaxis GO:0006935 247 0.336
Human Mouse
muscle cell development GO:0055001 133 0.329
Mouse
wound healing GO:0042060 157 0.329
Mouse
central nervous system neuron differentiation GO:0021953 162 0.328
positive regulation of protein kinase activity GO:0045860 144 0.326
Human Mouse Rat
ribose phosphate metabolic process GO:0019693 291 0.324
activation of immune response GO:0002253 138 0.317
positive regulation of calcium ion transport GO:0051928 27 0.317
Mouse
response to oxygen levels GO:0070482 62 0.316
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.313
cellular calcium ion homeostasis GO:0006874 119 0.311
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.309
regulation of hippo signaling GO:0035330 1 0.307
phosphatidylinositol metabolic process GO:0046488 45 0.306
Human Mouse
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.302
layer formation in cerebral cortex GO:0021819 13 0.301
rhodopsin mediated signaling pathway GO:0016056 4 0.300
steroid metabolic process GO:0008202 119 0.299
Mouse
negative regulation of axon guidance GO:1902668 8 0.296
negative regulation of cell migration GO:0030336 59 0.294
digestive system development GO:0055123 200 0.294
Mouse Fly
calcium ion transport GO:0006816 159 0.294
Mouse
coronary vasculature morphogenesis GO:0060977 9 0.290
Mouse
morphogenesis of a branching structure GO:0001763 203 0.290
cholesterol import GO:0070508 2 0.288
immune response regulating signaling pathway GO:0002764 125 0.287
kidney epithelium development GO:0072073 121 0.286
regulation of mapk cascade GO:0043408 248 0.285
Human Mouse Rat Fly
kidney vasculature development GO:0061440 15 0.285
Mouse
pigmentation GO:0043473 71 0.284
Mouse
detection of abiotic stimulus GO:0009582 60 0.284
Mouse
phospholipid catabolic process GO:0009395 5 0.283
neural crest cell development GO:0014032 48 0.281
axon guidance GO:0007411 141 0.280
cation transmembrane transport GO:0098655 266 0.278
cytokine mediated signaling pathway GO:0019221 115 0.275
Mouse
developmental pigmentation GO:0048066 40 0.275
Mouse
negative regulation of nervous system development GO:0051961 156 0.274
cardiac muscle fiber development GO:0048739 4 0.272
detection of mechanical stimulus GO:0050982 27 0.272
Mouse
artery development GO:0060840 53 0.272
Mouse
detection of stimulus GO:0051606 84 0.271
Mouse
cell substrate adhesion GO:0031589 130 0.271
regulation of protein tyrosine kinase activity GO:0061097 17 0.268
ribonucleotide metabolic process GO:0009259 291 0.267
cellular lipid metabolic process GO:0044255 323 0.267
Human Mouse
response to peptide hormone GO:0043434 127 0.266
Fly
epithelial cell differentiation involved in kidney development GO:0035850 23 0.263
regulation of extent of cell growth GO:0061387 52 0.263
cellular chemical homeostasis GO:0055082 215 0.263
positive regulation of cell substrate adhesion GO:0010811 47 0.262
hematopoietic progenitor cell differentiation GO:0002244 143 0.257
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.257
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.256
regulation of epithelial cell migration GO:0010632 35 0.256
mesenchymal cell differentiation GO:0048762 107 0.255
positive chemotaxis GO:0050918 18 0.255
regulation of actin filament based process GO:0032970 99 0.255
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.254
Mouse
metanephric glomerular endothelium development GO:0072264 1 0.254
alcohol metabolic process GO:0006066 116 0.254
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.249
regulation of vasculogenesis GO:2001212 9 0.249
Mouse
embryonic organ morphogenesis GO:0048562 276 0.248
Mouse
anatomical structure homeostasis GO:0060249 145 0.246
Mouse
regulation of retinal ganglion cell axon guidance GO:0090259 2 0.244
heart morphogenesis GO:0003007 178 0.244
tissue homeostasis GO:0001894 115 0.243
Mouse
regulation of system process GO:0044057 200 0.240
Zebrafish Rat
regulation of mesenchymal cell proliferation GO:0010464 37 0.239
Mouse
response to decreased oxygen levels GO:0036293 59 0.239
regulation of nucleoside metabolic process GO:0009118 130 0.237
cation homeostasis GO:0055080 212 0.237
Mouse
forebrain cell migration GO:0021885 58 0.232
actin cytoskeleton organization GO:0030036 220 0.230
Mouse Fly
regulation of anatomical structure size GO:0090066 178 0.229
phospholipid metabolic process GO:0006644 87 0.227
Human Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.225
purine containing compound metabolic process GO:0072521 311 0.224
photoreceptor cell differentiation GO:0046530 52 0.222
positive regulation of cell adhesion GO:0045785 80 0.219
developmental growth involved in morphogenesis GO:0060560 138 0.216
negative regulation of antigen receptor mediated signaling pathway GO:0050858 16 0.215
glycerolipid catabolic process GO:0046503 16 0.213
endocardium development GO:0003157 10 0.211
Mouse
regionalization GO:0003002 337 0.210
negative regulation of cell motility GO:2000146 61 0.210
semaphorin plexin signaling pathway GO:0071526 21 0.209
neuron projection extension GO:1990138 64 0.209
regulation of cell adhesion GO:0030155 154 0.207
regulation of gtp catabolic process GO:0033124 113 0.206
regulation of organelle organization GO:0033043 289 0.206
Mouse
inner ear morphogenesis GO:0042472 101 0.205
regulation of axon guidance GO:1902667 13 0.204
gamma aminobutyric acid signaling pathway GO:0007214 8 0.203
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.203
detection of stimulus involved in sensory perception GO:0050906 44 0.201
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.200
response to erythropoietin GO:0036017 1 0.200
Mouse
regulation of cd24 biosynthetic process GO:2000559 1 0.199
leukocyte migration GO:0050900 124 0.198
Human
regulation of epithelial cell proliferation GO:0050678 141 0.197
Mouse
cellular response to insulin stimulus GO:0032869 78 0.196
Fly
negative regulation of immune system process GO:0002683 209 0.195
Mouse
regulation of secretion GO:0051046 274 0.195
negative regulation of growth GO:0045926 99 0.195
renal system vasculature development GO:0061437 15 0.192
Mouse
ribonucleoside catabolic process GO:0042454 206 0.192
myotube differentiation GO:0014902 105 0.192
anatomical structure arrangement GO:0048532 20 0.192
hippocampus development GO:0021766 52 0.190
retina development in camera type eye GO:0060041 119 0.188
Mouse
locomotory behavior GO:0007626 195 0.188
striated muscle cell development GO:0055002 125 0.188
Mouse
regulation of neuron death GO:1901214 134 0.187
nucleoside phosphate metabolic process GO:0006753 338 0.187
respiratory tube development GO:0030323 167 0.186
Mouse
lung alveolus development GO:0048286 45 0.185
Mouse
stem cell development GO:0048864 219 0.183
divalent metal ion transport GO:0070838 172 0.183
Mouse
cell fate commitment GO:0045165 210 0.183
Mouse
erythrocyte differentiation GO:0030218 88 0.181
Mouse
hypothalamus cell migration GO:0021855 5 0.181
inflammatory response GO:0006954 244 0.180
Mouse
positive regulation of protein modification process GO:0031401 299 0.180
Human Mouse Rat
glycerolipid metabolic process GO:0046486 122 0.178
Human Mouse
glomerulus development GO:0032835 40 0.178
Mouse
motor neuron axon guidance GO:0008045 26 0.178
inorganic cation transmembrane transport GO:0098662 207 0.177
glycerophospholipid catabolic process GO:0046475 5 0.177
negative regulation of neuron apoptotic process GO:0043524 92 0.176
heart trabecula formation GO:0060347 14 0.176
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 16 0.176
Mouse
sensory perception GO:0007600 245 0.175
Mouse
nucleotide metabolic process GO:0009117 332 0.175
organic hydroxy compound metabolic process GO:1901615 203 0.175
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.174
forebrain generation of neurons GO:0021872 63 0.174
positive regulation of dendritic spine morphogenesis GO:0061003 8 0.174
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.174
Human Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.174
organic cyclic compound catabolic process GO:1901361 295 0.173
negative regulation of hormone biosynthetic process GO:0032353 4 0.172
leukocyte mediated immunity GO:0002443 174 0.172
Mouse
positive regulation of rho gtpase activity GO:0032321 41 0.172
autonomic nervous system development GO:0048483 43 0.172
cellular response to peptide GO:1901653 92 0.172
Fly
immune effector process GO:0002252 321 0.171
Mouse
regulation of map kinase activity GO:0043405 120 0.170
Human Mouse Rat
vasodilation GO:0042311 28 0.169
striated muscle contraction GO:0006941 45 0.167
negative regulation of receptor activity GO:2000272 5 0.165
glycosyl compound metabolic process GO:1901657 246 0.163
nephron development GO:0072006 109 0.163
Mouse
connective tissue development GO:0061448 179 0.163
Mouse
regulation of heart contraction GO:0008016 77 0.162
Zebrafish
positive regulation of vasculogenesis GO:2001214 7 0.161
Mouse
cardiac muscle cell contraction GO:0086003 7 0.159
mesenchymal cell development GO:0014031 93 0.159
regulation of cell substrate adhesion GO:0010810 73 0.158
amino acid transport GO:0006865 61 0.158
regulation of hydrolase activity GO:0051336 246 0.158
Human
glycoprotein biosynthetic process GO:0009101 89 0.157
rho protein signal transduction GO:0007266 32 0.157
regulation of cell size GO:0008361 72 0.157
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.155
fat cell differentiation GO:0045444 160 0.155
glycoprotein metabolic process GO:0009100 116 0.154
mitral valve morphogenesis GO:0003183 4 0.154
regulation of blood vessel remodeling GO:0060312 3 0.154
Mouse
sterol import GO:0035376 2 0.153
sensory perception of chemical stimulus GO:0007606 51 0.152
cerebral cortex radially oriented cell migration GO:0021799 31 0.152
epithelial cell proliferation GO:0050673 174 0.151
Mouse
regulation of receptor activity GO:0010469 41 0.151
endocytosis GO:0006897 168 0.150
organic acid transport GO:0015849 101 0.150
regulation of blood circulation GO:1903522 93 0.150
Zebrafish
skin development GO:0043588 220 0.150
glycerolipid biosynthetic process GO:0045017 50 0.149
forebrain neuron differentiation GO:0021879 52 0.149
lamellipodium organization GO:0097581 29 0.149
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.149
Mouse
cell migration involved in coronary angiogenesis GO:0060981 1 0.149
Mouse
calcium ion homeostasis GO:0055074 127 0.147
Mouse
cell growth GO:0016049 130 0.146
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.146
regulation of cell cycle process GO:0010564 160 0.146
Mouse
gtp metabolic process GO:0046039 144 0.145
sensory perception of mechanical stimulus GO:0050954 107 0.144
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.144
negative regulation of monocyte extravasation GO:2000438 1 0.143
nucleobase containing small molecule metabolic process GO:0055086 352 0.141
erythropoietin mediated signaling pathway GO:0038162 1 0.141
Mouse
dephosphorylation GO:0016311 129 0.141
carbohydrate derivative biosynthetic process GO:1901137 183 0.140
nucleoside triphosphate metabolic process GO:0009141 230 0.138
commissural neuron axon guidance GO:0071679 8 0.136
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 7 0.136
cognition GO:0050890 149 0.136
response to growth factor GO:0070848 198 0.135
negative regulation of homeostatic process GO:0032845 71 0.135
positive regulation of retinal ganglion cell axon guidance GO:1902336 2 0.135
ribonucleoside triphosphate catabolic process GO:0009203 199 0.134
regulation of glomerular filtration GO:0003093 3 0.134
venous blood vessel development GO:0060841 13 0.134
t cell activation GO:0042110 289 0.134
Mouse
negative regulation of sodium ion transmembrane transport GO:1902306 1 0.133
spermatid differentiation GO:0048515 115 0.133
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.133
response to oxidative stress GO:0006979 123 0.132
erk1 and erk2 cascade GO:0070371 77 0.132
Mouse
venous blood vessel morphogenesis GO:0048845 7 0.131
regulation of skeletal muscle fiber development GO:0048742 36 0.131
triglyceride biosynthetic process GO:0019432 17 0.131
regulation of monocyte extravasation GO:2000437 2 0.130
cellular divalent inorganic cation homeostasis GO:0072503 127 0.130
dendritic spine organization GO:0097061 26 0.130
mapk cascade GO:0000165 281 0.130
Human Mouse Rat Fly
glucose homeostasis GO:0042593 128 0.129
neural retina development GO:0003407 41 0.129
regulation of membrane potential GO:0042391 192 0.129
divalent inorganic cation transport GO:0072511 178 0.128
Mouse
diencephalon development GO:0021536 63 0.128
regulation of cardiac cell fate specification GO:2000043 1 0.127
stem cell differentiation GO:0048863 268 0.127
Mouse
plasma lipoprotein particle clearance GO:0034381 13 0.127
positive regulation of nucleotide catabolic process GO:0030813 88 0.125
negative regulation of cellular component organization GO:0051129 194 0.125
nucleoside triphosphate catabolic process GO:0009143 205 0.125
cardiac cell fate specification GO:0060912 2 0.125
cytosolic calcium ion homeostasis GO:0051480 70 0.124
regulation of axon extension GO:0030516 43 0.124
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.123
Mouse
negative regulation of molecular function GO:0044092 258 0.123
positive regulation of neural precursor cell proliferation GO:2000179 42 0.123
regulation of neural precursor cell proliferation GO:2000177 70 0.122
regulation of peptide hormone secretion GO:0090276 75 0.122
regulation of cellular component biogenesis GO:0044087 181 0.122
gtp catabolic process GO:0006184 143 0.122
positive regulation of stem cell proliferation GO:2000648 59 0.122
Mouse
metanephric mesenchymal cell migration GO:0035789 2 0.121
Mouse
actin cytoskeleton reorganization GO:0031532 21 0.121
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.121
kidney vasculature morphogenesis GO:0061439 7 0.121
Mouse
pro t cell differentiation GO:0002572 3 0.120
Mouse
male gamete generation GO:0048232 285 0.120
Mouse
memory GO:0007613 58 0.120
monocyte extravasation GO:0035696 2 0.119
metanephric mesangial cell differentiation GO:0072209 1 0.119
nitrogen compound transport GO:0071705 271 0.119
cell type specific apoptotic process GO:0097285 268 0.118
muscle adaptation GO:0043500 39 0.117
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.117
Mouse
response to light stimulus GO:0009416 135 0.117
regulation of cell activation GO:0050865 289 0.116
Mouse
regulation of neuron projection development GO:0010975 169 0.116
renal system process GO:0003014 48 0.116
neural crest cell migration GO:0001755 32 0.116
digestion GO:0007586 40 0.115
carbohydrate derivative catabolic process GO:1901136 231 0.115
nucleotide catabolic process GO:0009166 217 0.115
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.115
Mouse
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.115
Mouse
positive regulation of behavior GO:0048520 40 0.114
Mouse
outflow tract morphogenesis GO:0003151 53 0.113
regulation of homeostatic process GO:0032844 182 0.113
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.113
neuromuscular process GO:0050905 99 0.113
endodermal cell fate specification GO:0001714 4 0.112
positive regulation of gtp catabolic process GO:0033126 85 0.111
positive regulation of growth GO:0045927 104 0.111
positive regulation of transmembrane transport GO:0034764 29 0.110
Mouse
regulation of calcium ion transport GO:0051924 69 0.110
Mouse
apoptotic signaling pathway GO:0097190 306 0.110
glycosyl compound catabolic process GO:1901658 206 0.110
b 1 b cell differentiation GO:0001923 3 0.109
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.108
cellular biogenic amine metabolic process GO:0006576 28 0.107
hindbrain development GO:0030902 128 0.107
cyclic nucleotide metabolic process GO:0009187 59 0.107
embryonic epithelial tube formation GO:0001838 130 0.106
positive regulation of cell growth GO:0030307 33 0.106
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.106
Mouse
positive regulation of gtpase activity GO:0043547 85 0.106
bronchus cartilage development GO:0060532 2 0.106
regulation of ion transmembrane transporter activity GO:0032412 54 0.105
cytoplasmic transport GO:0016482 234 0.105
purine nucleoside catabolic process GO:0006152 205 0.105
brown fat cell differentiation GO:0050873 36 0.104
male sex differentiation GO:0046661 109 0.104
Mouse Fly
dendritic spine development GO:0060996 30 0.103
melanocyte adhesion GO:0097326 1 0.103
Mouse
axon extension involved in axon guidance GO:0048846 14 0.103
positive regulation of neuroblast proliferation GO:0002052 19 0.103
regulation of heart rate GO:0002027 36 0.102
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.102
Mouse
exocrine system development GO:0035272 45 0.101
Fly
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.101
positive regulation of triglyceride metabolic process GO:0090208 9 0.101
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.100
Human Mouse
cytosolic calcium ion transport GO:0060401 48 0.100
regulation of cytoskeleton organization GO:0051493 122 0.100
Mouse
regulation of lipase activity GO:0060191 15 0.100
Human
establishment of protein localization to membrane GO:0090150 54 0.099
regulation of secretion by cell GO:1903530 249 0.099
digestive tract development GO:0048565 190 0.099
Mouse Fly
response to epidermal growth factor GO:0070849 4 0.099
epithelial cell development GO:0002064 159 0.099
Fly
cell activation involved in immune response GO:0002263 126 0.098
aromatic compound catabolic process GO:0019439 286 0.098
regulation of blood vessel size GO:0050880 56 0.098
positive regulation of endothelial cell migration GO:0010595 12 0.098
ribonucleoside metabolic process GO:0009119 245 0.098
muscle cell migration GO:0014812 19 0.097
Mouse
gonad development GO:0008406 141 0.097
Mouse
regulation of peptide secretion GO:0002791 77 0.097
negative regulation of hormone metabolic process GO:0032351 4 0.097
cellular nitrogen compound catabolic process GO:0044270 280 0.096
neutral lipid biosynthetic process GO:0046460 18 0.096
skeletal muscle organ development GO:0060538 163 0.096
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.096
metanephric nephron development GO:0072210 34 0.096
Mouse
cell migration involved in vasculogenesis GO:0035441 2 0.096
Mouse
smooth muscle tissue development GO:0048745 22 0.094
Mouse
rac protein signal transduction GO:0016601 13 0.094
negative regulation of endothelial cell migration GO:0010596 4 0.094
organic anion transport GO:0015711 137 0.093
purine ribonucleotide catabolic process GO:0009154 208 0.093
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.093
Mouse
negative regulation of cell growth GO:0030308 44 0.093
ventral spinal cord development GO:0021517 48 0.093
positive regulation of apoptotic process GO:0043065 217 0.093
glomerular mesangial cell proliferation GO:0072110 3 0.093
Mouse
mesonephric tubule development GO:0072164 94 0.092
generation of precursor metabolites and energy GO:0006091 103 0.092
neuron projection guidance GO:0097485 141 0.092
myotube cell development GO:0014904 60 0.091
negative regulation of neuron differentiation GO:0045665 101 0.091
negative regulation of kinase activity GO:0033673 81 0.091
hormone metabolic process GO:0042445 86 0.091
Mouse

Flt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.346
cardiovascular system disease DOID:1287 0 0.346
nervous system disease DOID:863 0 0.113