Mus musculus

90 known processes

Rnaseh2b

ribonuclease H2, subunit B

(Aliases: 1110019N06Rik,Dleu8,2610207P08Rik)

Rnaseh2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.386
dna repair GO:0006281 107 0.157
dna metabolic process GO:0006259 303 0.143
nucleotide metabolic process GO:0009117 332 0.117
regulation of cellular response to stress GO:0080135 159 0.116
meiotic cell cycle process GO:1903046 77 0.101
macromolecule catabolic process GO:0009057 281 0.097
double strand break repair GO:0006302 48 0.083
meiosis i GO:0007127 60 0.078
cellular nitrogen compound catabolic process GO:0044270 280 0.075
nucleoside phosphate catabolic process GO:1901292 222 0.070
development of primary sexual characteristics GO:0045137 143 0.067
apoptotic signaling pathway GO:0097190 306 0.066
cellular ketone metabolic process GO:0042180 84 0.066
ribonucleoside triphosphate metabolic process GO:0009199 220 0.066
recombinational repair GO:0000725 21 0.065
negative regulation of protein metabolic process GO:0051248 282 0.064
response to oxidative stress GO:0006979 123 0.062
protein catabolic process GO:0030163 221 0.060
cellular protein catabolic process GO:0044257 155 0.058
nucleobase containing small molecule metabolic process GO:0055086 352 0.058
regulation of cell cycle GO:0051726 281 0.055
double strand break repair via nonhomologous end joining GO:0006303 10 0.054
peptidyl amino acid modification GO:0018193 336 0.054
organic cyclic compound catabolic process GO:1901361 295 0.053
meiotic cell cycle GO:0051321 122 0.053
purine nucleoside metabolic process GO:0042278 241 0.052
response to organic cyclic compound GO:0014070 198 0.052
dna replication independent nucleosome assembly GO:0006336 1 0.051
purine containing compound metabolic process GO:0072521 311 0.050
spermatogenesis GO:0007283 284 0.049
gonad development GO:0008406 141 0.049
purine nucleotide metabolic process GO:0006163 302 0.048
organelle fission GO:0048285 170 0.048
synapsis GO:0007129 34 0.047
protein maturation GO:0051604 176 0.047
cellular macromolecule catabolic process GO:0044265 206 0.047
cellular amino acid metabolic process GO:0006520 103 0.047
regulation of cellular ketone metabolic process GO:0010565 66 0.046
negative regulation of molecular function GO:0044092 258 0.046
germ cell development GO:0007281 185 0.044
ribonucleotide metabolic process GO:0009259 291 0.044
nuclear division GO:0000280 158 0.043
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
positive regulation of protein modification process GO:0031401 299 0.042
cellular amine metabolic process GO:0044106 44 0.042
purine nucleotide catabolic process GO:0006195 211 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.041
ribonucleotide catabolic process GO:0009261 208 0.041
glycosyl compound metabolic process GO:1901657 246 0.041
microtubule cytoskeleton organization GO:0000226 157 0.040
ribose phosphate metabolic process GO:0019693 291 0.040
oxidation reduction process GO:0055114 342 0.040
regulation of cellular catabolic process GO:0031329 242 0.040
carbohydrate derivative catabolic process GO:1901136 231 0.039
chromatin modification GO:0016568 187 0.037
purine nucleoside triphosphate catabolic process GO:0009146 203 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.035
ribonucleoside catabolic process GO:0042454 206 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
protein oligomerization GO:0051259 67 0.035
mitotic cell cycle process GO:1903047 159 0.035
purine ribonucleotide catabolic process GO:0009154 208 0.035
response to ionizing radiation GO:0010212 42 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.034
signal transduction by p53 class mediator GO:0072331 51 0.034
regulation of hydrolase activity GO:0051336 246 0.034
purine containing compound catabolic process GO:0072523 213 0.033
purine ribonucleoside catabolic process GO:0046130 205 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.033
organelle localization GO:0051640 179 0.033
regulation of protein maturation GO:1903317 96 0.033
organophosphate catabolic process GO:0046434 232 0.033
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
cytoplasmic transport GO:0016482 234 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
covalent chromatin modification GO:0016569 163 0.031
methylation GO:0032259 134 0.031
ossification GO:0001503 216 0.031
aromatic compound catabolic process GO:0019439 286 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
intrinsic apoptotic signaling pathway GO:0097193 132 0.030
ribonucleoside metabolic process GO:0009119 245 0.030
histone acetylation GO:0016573 41 0.029
negative regulation of fibroblast apoptotic process GO:2000270 6 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.029
histone modification GO:0016570 159 0.029
amine metabolic process GO:0009308 45 0.029
microtubule based process GO:0007017 236 0.028
chromatin organization GO:0006325 206 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.028
protein processing GO:0016485 163 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
peptidyl lysine modification GO:0018205 77 0.026
mapk cascade GO:0000165 281 0.026
cell type specific apoptotic process GO:0097285 268 0.026
nucleoside metabolic process GO:0009116 246 0.026
positive regulation of apoptotic process GO:0043065 217 0.026
regulation of proteolysis GO:0030162 164 0.026
protein homooligomerization GO:0051260 43 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
chromosome organization involved in meiosis GO:0070192 39 0.025
regulation of mapk cascade GO:0043408 248 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.025
nucleotide catabolic process GO:0009166 217 0.024
regulation of peptidase activity GO:0052547 96 0.024
response to inorganic substance GO:0010035 96 0.024
nitrogen compound transport GO:0071705 271 0.024
ribonucleoside monophosphate metabolic process GO:0009161 80 0.024
intracellular protein transport GO:0006886 204 0.024
negative regulation of transferase activity GO:0051348 85 0.024
dephosphorylation GO:0016311 129 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
heterocycle catabolic process GO:0046700 280 0.022
cellular lipid metabolic process GO:0044255 323 0.022
regulation of protein processing GO:0070613 96 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.022
leukocyte differentiation GO:0002521 342 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
modification dependent macromolecule catabolic process GO:0043632 133 0.021
dna replication GO:0006260 52 0.021
homeostasis of number of cells GO:0048872 210 0.021
regulation of lipid metabolic process GO:0019216 118 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
mrna metabolic process GO:0016071 84 0.021
chromosome segregation GO:0007059 48 0.021
negative regulation of protein maturation GO:1903318 79 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
nucleoside monophosphate catabolic process GO:0009125 59 0.021
regulation of transferase activity GO:0051338 263 0.021
male gamete generation GO:0048232 285 0.020
cellular chemical homeostasis GO:0055082 215 0.020
mitotic cell cycle GO:0000278 195 0.020
spindle organization GO:0007051 28 0.020
protein localization to nucleus GO:0034504 121 0.020
regulation of organelle organization GO:0033043 289 0.020
positive regulation of cellular catabolic process GO:0031331 148 0.020
dendrite development GO:0016358 115 0.020
cellular response to oxidative stress GO:0034599 76 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.019
dna dependent dna replication GO:0006261 24 0.019
nucleoside monophosphate metabolic process GO:0009123 85 0.019
leukocyte proliferation GO:0070661 172 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
nucleoside catabolic process GO:0009164 206 0.019
cation transport GO:0006812 399 0.019
protein localization to organelle GO:0033365 185 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
regulation of secretion GO:0051046 274 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
mitochondrion organization GO:0007005 134 0.019
positive regulation of cell death GO:0010942 224 0.018
nuclear transport GO:0051169 139 0.018
response to radiation GO:0009314 165 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
atp catabolic process GO:0006200 55 0.018
anatomical structure homeostasis GO:0060249 145 0.018
translesion synthesis GO:0019985 1 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
meiotic nuclear division GO:0007126 115 0.017
lymphocyte differentiation GO:0030098 242 0.017
muscle cell differentiation GO:0042692 261 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
regulation of protein catabolic process GO:0042176 108 0.017
protein acylation GO:0043543 64 0.017
lateral inhibition GO:0046331 1 0.017
positive regulation of cell cycle GO:0045787 92 0.017
response to organonitrogen compound GO:0010243 246 0.017
deoxyribose phosphate metabolic process GO:0019692 9 0.017
purine nucleoside monophosphate metabolic process GO:0009126 81 0.016
ribonucleoside monophosphate catabolic process GO:0009158 57 0.016
anion transport GO:0006820 177 0.016
mitotic nuclear division GO:0007067 48 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
ion transmembrane transport GO:0034220 361 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
synaptonemal complex assembly GO:0007130 13 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
regulation of protein kinase activity GO:0045859 232 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
regulation of cell growth GO:0001558 91 0.016
protein import into nucleus GO:0006606 95 0.016
response to oxygen levels GO:0070482 62 0.015
carbohydrate homeostasis GO:0033500 128 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
negative regulation of immune system process GO:0002683 209 0.015
regulation of cellular protein catabolic process GO:1903362 61 0.015
protein ubiquitination GO:0016567 171 0.015
rna processing GO:0006396 105 0.015
protein targeting GO:0006605 143 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
cellular response to radiation GO:0071478 28 0.015
endocytosis GO:0006897 168 0.015
regulation of chromosome organization GO:0033044 83 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.014
regulation of secretion by cell GO:1903530 249 0.014
peptide hormone secretion GO:0030072 109 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.014
positive regulation of organelle organization GO:0010638 128 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
amide transport GO:0042886 138 0.014
myeloid cell differentiation GO:0030099 233 0.014
response to uv GO:0009411 44 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
cellular response to lipid GO:0071396 145 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
non recombinational repair GO:0000726 10 0.014
intracellular mrna localization GO:0008298 4 0.014
intra s dna damage checkpoint GO:0031573 4 0.014
neuron death GO:0070997 154 0.013
regulation of cell division GO:0051302 76 0.013
positive regulation of cell development GO:0010720 237 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
atp metabolic process GO:0046034 75 0.013
response to acid chemical GO:0001101 111 0.013
blastocyst development GO:0001824 80 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
mrna processing GO:0006397 63 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
inflammatory response GO:0006954 244 0.013
dna recombination GO:0006310 92 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
negative regulation of protein modification process GO:0031400 163 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
cellular homeostasis GO:0019725 240 0.013
regulation of inflammatory response GO:0050727 147 0.013
response to growth factor GO:0070848 198 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
stem cell differentiation GO:0048863 268 0.012
peptidyl lysine acetylation GO:0018394 45 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
locomotory behavior GO:0007626 195 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of defense response GO:0031347 233 0.012
fatty acid metabolic process GO:0006631 121 0.012
organelle assembly GO:0070925 177 0.012
female meiotic division GO:0007143 21 0.012
regulation of embryonic development GO:0045995 71 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
fertilization GO:0009566 127 0.012
regulation of neuron death GO:1901214 134 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
negative regulation of proteolysis GO:0045861 74 0.012
inner cell mass cell proliferation GO:0001833 15 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
cell adhesion GO:0007155 329 0.012
regulation of homeostatic process GO:0032844 182 0.012
double strand break repair via homologous recombination GO:0000724 21 0.012
regulation of protein localization GO:0032880 231 0.012
lipid biosynthetic process GO:0008610 179 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
asymmetric stem cell division GO:0098722 3 0.011
regulation of hormone levels GO:0010817 211 0.011
deoxyribonucleotide metabolic process GO:0009262 14 0.011
axonogenesis GO:0007409 274 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
mrna splicing via spliceosome GO:0000398 43 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
cell fate commitment GO:0045165 210 0.011
lymphocyte proliferation GO:0046651 164 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
myeloid cell homeostasis GO:0002262 114 0.011
spermatid development GO:0007286 108 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
internal protein amino acid acetylation GO:0006475 42 0.011
developmental maturation GO:0021700 193 0.011
macromolecule methylation GO:0043414 120 0.011
telencephalon development GO:0021537 186 0.011
cellular response to acid chemical GO:0071229 68 0.011
b cell activation GO:0042113 161 0.011
cell growth GO:0016049 130 0.011
response to light stimulus GO:0009416 135 0.011
positive regulation of nervous system development GO:0051962 221 0.011
cell maturation GO:0048469 127 0.011
regulation of dna recombination GO:0000018 34 0.011
positive regulation of kinase activity GO:0033674 155 0.011
cell division GO:0051301 120 0.011
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
peptide transport GO:0015833 133 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
forebrain development GO:0030900 302 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
negative regulation of phagocytosis GO:0050765 4 0.010
positive regulation of secretion GO:0051047 130 0.010
muscle cell development GO:0055001 133 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010

Rnaseh2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016
nervous system disease DOID:863 0 0.013
disease of anatomical entity DOID:7 0 0.013