Mus musculus

18 known processes

Eif3c

eukaryotic translation initiation factor 3, subunit C

(Aliases: MGC36637,NipilA3,NIPIL(A3),3230401O13Rik,Eif3s8,110kDa)

Eif3c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoplasmic translational initiation GO:0002183 3 0.969
translational initiation GO:0006413 24 0.852
translation GO:0006412 93 0.760
trna aminoacylation for protein translation GO:0006418 1 0.732
amino acid activation GO:0043038 1 0.611
trna metabolic process GO:0006399 11 0.555
cellular amino acid metabolic process GO:0006520 103 0.337
ribonucleoprotein complex subunit organization GO:0071826 28 0.315
dna repair GO:0006281 107 0.228
purine nucleoside catabolic process GO:0006152 205 0.168
dna dealkylation GO:0035510 11 0.151
aromatic compound catabolic process GO:0019439 286 0.143
cellular response to dna damage stimulus GO:0006974 207 0.126
nucleoside monophosphate catabolic process GO:0009125 59 0.112
protein modification by small protein conjugation or removal GO:0070647 207 0.104
ribonucleoside catabolic process GO:0042454 206 0.097
protein ubiquitination GO:0016567 171 0.097
regulation of cellular amino acid metabolic process GO:0006521 5 0.088
trna aminoacylation GO:0043039 1 0.087
nucleotide metabolic process GO:0009117 332 0.082
purine containing compound metabolic process GO:0072521 311 0.082
response to amino acid GO:0043200 37 0.076
nucleobase containing small molecule metabolic process GO:0055086 352 0.064
mrna metabolic process GO:0016071 84 0.063
purine containing compound catabolic process GO:0072523 213 0.063
molting cycle GO:0042303 90 0.060
posttranscriptional regulation of gene expression GO:0010608 155 0.057
nucleoside triphosphate metabolic process GO:0009141 230 0.056
cellular nitrogen compound catabolic process GO:0044270 280 0.056
mitotic cell cycle GO:0000278 195 0.054
ribonucleoside monophosphate catabolic process GO:0009158 57 0.053
ribonucleotide catabolic process GO:0009261 208 0.053
microtubule based process GO:0007017 236 0.051
purine ribonucleoside catabolic process GO:0046130 205 0.049
positive regulation of protein modification process GO:0031401 299 0.047
organophosphate catabolic process GO:0046434 232 0.046
carbohydrate derivative catabolic process GO:1901136 231 0.043
spindle assembly involved in mitosis GO:0090307 4 0.043
purine nucleoside triphosphate metabolic process GO:0009144 226 0.043
cellular amine metabolic process GO:0044106 44 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.042
purine ribonucleoside metabolic process GO:0046128 241 0.038
cellular response to cytokine stimulus GO:0071345 189 0.038
protein modification by small protein conjugation GO:0032446 187 0.038
regulation of translation GO:0006417 71 0.038
axonogenesis GO:0007409 274 0.037
response to acid chemical GO:0001101 111 0.037
endocytosis GO:0006897 168 0.036
ribonucleoside triphosphate metabolic process GO:0009199 220 0.035
nucleotide excision repair dna incision GO:0033683 1 0.034
nucleoside metabolic process GO:0009116 246 0.034
atp catabolic process GO:0006200 55 0.033
heterocycle catabolic process GO:0046700 280 0.033
nucleotide catabolic process GO:0009166 217 0.032
glycosyl compound metabolic process GO:1901657 246 0.032
purine nucleotide metabolic process GO:0006163 302 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
regulation of cell division GO:0051302 76 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
nucleobase containing compound transport GO:0015931 27 0.030
neuron apoptotic process GO:0051402 142 0.030
positive regulation of programmed cell death GO:0043068 218 0.029
neuron death GO:0070997 154 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.028
organelle assembly GO:0070925 177 0.028
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.028
cellular ketone metabolic process GO:0042180 84 0.028
regulation of mrna splicing via spliceosome GO:0048024 32 0.028
regulation of mitotic cell cycle GO:0007346 126 0.028
signal transduction by p53 class mediator GO:0072331 51 0.028
microtubule cytoskeleton organization GO:0000226 157 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.027
regulation of organelle organization GO:0033043 289 0.026
mitotic cell cycle process GO:1903047 159 0.026
cellular protein complex assembly GO:0043623 116 0.025
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.025
epidermis development GO:0008544 187 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
amine metabolic process GO:0009308 45 0.024
cell growth GO:0016049 130 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regulation of protein localization GO:0032880 231 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
regulation of mitotic cell cycle phase transition GO:1901990 73 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
cellular protein catabolic process GO:0044257 155 0.023
methylation GO:0032259 134 0.023
sperm egg recognition GO:0035036 37 0.023
regulation of protein targeting GO:1903533 61 0.022
regulation of protein complex assembly GO:0043254 83 0.022
rna processing GO:0006396 105 0.022
stem cell differentiation GO:0048863 268 0.022
nucleoside monophosphate metabolic process GO:0009123 85 0.022
regulation of cell cycle GO:0051726 281 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
regulation of cellular ketone metabolic process GO:0010565 66 0.021
regulation of cellular component size GO:0032535 121 0.021
actin cytoskeleton organization GO:0030036 220 0.021
embryonic organ morphogenesis GO:0048562 276 0.021
protein processing GO:0016485 163 0.021
placenta development GO:0001890 140 0.021
germ cell development GO:0007281 185 0.021
purine nucleoside monophosphate catabolic process GO:0009128 58 0.021
atp metabolic process GO:0046034 75 0.020
regulation of translational initiation GO:0006446 15 0.020
intracellular protein transport GO:0006886 204 0.020
stem cell development GO:0048864 219 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
regulation of protein localization to nucleus GO:1900180 60 0.019
regulation of cell cycle process GO:0010564 160 0.019
regulation of transposition GO:0010528 2 0.019
regulation of protein transport GO:0051223 163 0.018
binding of sperm to zona pellucida GO:0007339 34 0.018
nucleoside catabolic process GO:0009164 206 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
negative regulation of neuron apoptotic process GO:0043524 92 0.017
maintenance of location GO:0051235 89 0.017
chemotaxis GO:0006935 247 0.017
macromolecule catabolic process GO:0009057 281 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
ossification GO:0001503 216 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
regulation of mrna metabolic process GO:1903311 43 0.017
cation transmembrane transport GO:0098655 266 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
dna metabolic process GO:0006259 303 0.017
cell type specific apoptotic process GO:0097285 268 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
transmission of nerve impulse GO:0019226 76 0.016
chromatin organization GO:0006325 206 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
positive regulation of cell death GO:0010942 224 0.016
protein import GO:0017038 101 0.016
gland development GO:0048732 330 0.016
demethylation GO:0070988 23 0.015
rna localization GO:0006403 23 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
neuromuscular process GO:0050905 99 0.015
t cell activation GO:0042110 289 0.015
regulation of tor signaling GO:0032006 17 0.015
epithelial cell proliferation GO:0050673 174 0.015
positive regulation of protein complex assembly GO:0031334 45 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
heart morphogenesis GO:0003007 178 0.015
transcription coupled nucleotide excision repair GO:0006283 2 0.015
regulation of response to dna damage stimulus GO:2001020 34 0.015
female gamete generation GO:0007292 74 0.015
protein import into nucleus GO:0006606 95 0.015
protein polymerization GO:0051258 57 0.014
ion transmembrane transport GO:0034220 361 0.014
cellular response to amino acid stimulus GO:0071230 29 0.014
skin development GO:0043588 220 0.014
wound healing GO:0042060 157 0.014
cell adhesion GO:0007155 329 0.014
mitotic cytokinesis GO:0000281 4 0.014
negative regulation of cell cycle GO:0045786 123 0.014
nuclear transport GO:0051169 139 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
nucleocytoplasmic transport GO:0006913 139 0.013
cellular response to lipid GO:0071396 145 0.013
myeloid cell differentiation GO:0030099 233 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
protein folding GO:0006457 28 0.013
regulation of protein kinase activity GO:0045859 232 0.013
protein maturation GO:0051604 176 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
spermatid differentiation GO:0048515 115 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
response to organonitrogen compound GO:0010243 246 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
sensory organ morphogenesis GO:0090596 242 0.012
nitrogen compound transport GO:0071705 271 0.012
transmembrane transport GO:0055085 412 0.012
purine containing compound biosynthetic process GO:0072522 70 0.012
negative regulation of protein modification process GO:0031400 163 0.012
rhythmic process GO:0048511 174 0.012
fertilization GO:0009566 127 0.012
regulation of kinase activity GO:0043549 249 0.012
protein targeting GO:0006605 143 0.012
embryonic heart tube development GO:0035050 65 0.012
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.012
mesenchyme development GO:0060485 152 0.012
rna splicing GO:0008380 54 0.012
nuclear import GO:0051170 95 0.012
negative regulation of neuron death GO:1901215 98 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
nuclear division GO:0000280 158 0.012
myeloid leukocyte differentiation GO:0002573 119 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
chromatin modification GO:0016568 187 0.011
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.011
cerebellar purkinje cell layer development GO:0021680 26 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
positive regulation of intracellular protein transport GO:0090316 42 0.011
hindbrain development GO:0030902 128 0.011
tor signaling GO:0031929 21 0.011
camera type eye development GO:0043010 266 0.011
body morphogenesis GO:0010171 45 0.011
localization within membrane GO:0051668 4 0.011
organelle fission GO:0048285 170 0.011
homeostasis of number of cells GO:0048872 210 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
interspecies interaction between organisms GO:0044419 83 0.010
hepaticobiliary system development GO:0061008 67 0.010
organonitrogen compound catabolic process GO:1901565 264 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010

Eif3c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.603
disease of anatomical entity DOID:7 0 0.603
nervous system disease DOID:863 0 0.603
neuropathy DOID:870 0 0.603
charcot marie tooth disease DOID:10595 0 0.481
retinal disease DOID:5679 0 0.082
sensory system disease DOID:0050155 0 0.082
eye and adnexa disease DOID:1492 0 0.082
eye disease DOID:5614 0 0.082
charcot marie tooth disease type 2 DOID:0050539 0 0.075
central nervous system disease DOID:331 0 0.053
retinal degeneration DOID:8466 0 0.044
neurodegenerative disease DOID:1289 0 0.041