Mus musculus

0 known processes

Nexn

nexilin

(Aliases: 1110046H09Rik,AA553326,NELIN)

Nexn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.078
cellular amine metabolic process GO:0044106 44 0.068
muscle cell differentiation GO:0042692 261 0.064
Zebrafish
muscle tissue development GO:0060537 308 0.063
Zebrafish
organelle assembly GO:0070925 177 0.054
amine metabolic process GO:0009308 45 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
regulation of cellular ketone metabolic process GO:0010565 66 0.051
striated muscle tissue development GO:0014706 293 0.049
Zebrafish
muscle cell development GO:0055001 133 0.047
Zebrafish
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
regulation of cellular amine metabolic process GO:0033238 20 0.045
ras protein signal transduction GO:0007265 77 0.044
cellular component assembly involved in morphogenesis GO:0010927 139 0.044
heart morphogenesis GO:0003007 178 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
cellular amino acid metabolic process GO:0006520 103 0.042
cytoplasmic transport GO:0016482 234 0.042
cellular ketone metabolic process GO:0042180 84 0.040
striated muscle cell development GO:0055002 125 0.040
Zebrafish
cation transport GO:0006812 399 0.039
regulation of organelle organization GO:0033043 289 0.039
Human
muscle system process GO:0003012 141 0.036
ribonucleotide metabolic process GO:0009259 291 0.036
transmembrane transport GO:0055085 412 0.036
regulation of system process GO:0044057 200 0.035
nucleotide metabolic process GO:0009117 332 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
purine nucleotide metabolic process GO:0006163 302 0.032
negative regulation of cellular component organization GO:0051129 194 0.032
circulatory system process GO:0003013 197 0.031
heart contraction GO:0060047 93 0.030
peptidyl amino acid modification GO:0018193 336 0.030
apoptotic signaling pathway GO:0097190 306 0.029
purine containing compound metabolic process GO:0072521 311 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
cellular protein complex assembly GO:0043623 116 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
glycosyl compound metabolic process GO:1901657 246 0.027
regulation of hydrolase activity GO:0051336 246 0.027
actin filament organization GO:0007015 113 0.027
ribonucleoside catabolic process GO:0042454 206 0.027
organic cyclic compound catabolic process GO:1901361 295 0.027
microtubule based process GO:0007017 236 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
heterocycle catabolic process GO:0046700 280 0.026
organophosphate catabolic process GO:0046434 232 0.026
regulation of intracellular transport GO:0032386 159 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
heart process GO:0003015 94 0.026
ribonucleotide catabolic process GO:0009261 208 0.026
cytokine production GO:0001816 319 0.025
regulation of cell cycle GO:0051726 281 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.025
aromatic compound catabolic process GO:0019439 286 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
macromolecule catabolic process GO:0009057 281 0.025
myosin filament organization GO:0031033 3 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.025
nucleoside catabolic process GO:0009164 206 0.025
regulation of cellular component biogenesis GO:0044087 181 0.025
regulation of apoptotic signaling pathway GO:2001233 197 0.025
intracellular protein transport GO:0006886 204 0.025
regulation of cytokine production GO:0001817 266 0.025
blood circulation GO:0008015 195 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
cell adhesion GO:0007155 329 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
nucleoside metabolic process GO:0009116 246 0.024
actomyosin structure organization GO:0031032 56 0.024
cardiac muscle tissue development GO:0048738 130 0.024
Zebrafish
ion transmembrane transport GO:0034220 361 0.024
mitotic cell cycle GO:0000278 195 0.024
ribose phosphate metabolic process GO:0019693 291 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
second messenger mediated signaling GO:0019932 73 0.023
regulation of cell activation GO:0050865 289 0.023
oxidation reduction process GO:0055114 342 0.023
purine containing compound catabolic process GO:0072523 213 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
negative regulation of phosphorylation GO:0042326 166 0.022
nucleotide catabolic process GO:0009166 217 0.022
regulation of cytoskeleton organization GO:0051493 122 0.022
Human
development of primary sexual characteristics GO:0045137 143 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
peptidyl serine modification GO:0018209 83 0.022
anatomical structure homeostasis GO:0060249 145 0.022
regionalization GO:0003002 337 0.022
myosin filament assembly GO:0031034 2 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
immune effector process GO:0002252 321 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
dna metabolic process GO:0006259 303 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
negative regulation of molecular function GO:0044092 258 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
rho protein signal transduction GO:0007266 32 0.021
sequestering of calcium ion GO:0051208 18 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
regulation of protein kinase activity GO:0045859 232 0.021
nuclear transport GO:0051169 139 0.020
cellular homeostasis GO:0019725 240 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
renal system development GO:0072001 225 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
sensory perception GO:0007600 245 0.020
regulation of actin filament based process GO:0032970 99 0.020
regulation of cell projection organization GO:0031344 206 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
positive regulation of protein modification process GO:0031401 299 0.020
organelle fission GO:0048285 170 0.020
tissue homeostasis GO:0001894 115 0.020
striated muscle myosin thick filament assembly GO:0071688 1 0.020
stem cell differentiation GO:0048863 268 0.020
t cell activation GO:0042110 289 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
negative regulation of protein modification process GO:0031400 163 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
cellular lipid metabolic process GO:0044255 323 0.019
compound eye development GO:0048749 1 0.019
regulation of protein localization GO:0032880 231 0.019
regulation of cell motility GO:2000145 236 0.019
Human
purine ribonucleoside metabolic process GO:0046128 241 0.019
maintenance of location GO:0051235 89 0.019
spermatogenesis GO:0007283 284 0.019
cation transmembrane transport GO:0098655 266 0.019
cellular chemical homeostasis GO:0055082 215 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
gonad development GO:0008406 141 0.019
actin mediated cell contraction GO:0070252 15 0.019
mitotic cell cycle process GO:1903047 159 0.019
cellular ion homeostasis GO:0006873 165 0.018
intrinsic apoptotic signaling pathway GO:0097193 132 0.018
extracellular structure organization GO:0043062 148 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
response to organonitrogen compound GO:0010243 246 0.018
response to growth factor GO:0070848 198 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.018
carbohydrate metabolic process GO:0005975 230 0.018
cardiac chamber development GO:0003205 108 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
regulation of ion transport GO:0043269 215 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
muscle fiber development GO:0048747 76 0.018
Zebrafish
organonitrogen compound biosynthetic process GO:1901566 192 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
organelle localization GO:0051640 179 0.017
regulation of anatomical structure size GO:0090066 178 0.017
protein ubiquitination GO:0016567 171 0.017
urogenital system development GO:0001655 261 0.017
divalent inorganic cation transport GO:0072511 178 0.017
cell type specific apoptotic process GO:0097285 268 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
actin filament based movement GO:0030048 23 0.017
regulation of membrane potential GO:0042391 192 0.017
camera type eye development GO:0043010 266 0.017
forebrain development GO:0030900 302 0.017
homeostasis of number of cells GO:0048872 210 0.017
microtubule cytoskeleton organization GO:0000226 157 0.016
leukocyte differentiation GO:0002521 342 0.016
protein catabolic process GO:0030163 221 0.016
neuron death GO:0070997 154 0.016
glycoprotein metabolic process GO:0009100 116 0.016
actin filament polymerization GO:0030041 44 0.016
cardiac chamber morphogenesis GO:0003206 93 0.016
skeletal muscle organ development GO:0060538 163 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
response to transforming growth factor beta GO:0071559 88 0.016
cation homeostasis GO:0055080 212 0.016
protein polymerization GO:0051258 57 0.016
protein localization to organelle GO:0033365 185 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
regulation of transmembrane transport GO:0034762 128 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
myotube differentiation GO:0014902 105 0.016
regulation of secretion GO:0051046 274 0.016
wound healing GO:0042060 157 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
regulation of actin cytoskeleton organization GO:0032956 84 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
regulation of transferase activity GO:0051338 263 0.015
cell division GO:0051301 120 0.015
negative regulation of immune system process GO:0002683 209 0.015
regulation of mapk cascade GO:0043408 248 0.015
calcium ion homeostasis GO:0055074 127 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
cardiac muscle contraction GO:0060048 32 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
mitotic cytokinesis GO:0000281 4 0.015
sequestering of metal ion GO:0051238 19 0.015
regulation of muscle system process GO:0090257 80 0.015
response to organic cyclic compound GO:0014070 198 0.015
cell substrate adhesion GO:0031589 130 0.015
actin polymerization or depolymerization GO:0008154 54 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
nuclear division GO:0000280 158 0.015
positive regulation of organelle organization GO:0010638 128 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
epithelial cell development GO:0002064 159 0.015
response to radiation GO:0009314 165 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
protein processing GO:0016485 163 0.015
cell growth GO:0016049 130 0.015
protein localization to nucleus GO:0034504 121 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
sensory organ morphogenesis GO:0090596 242 0.015
regulation of cell cycle process GO:0010564 160 0.015
positive regulation of cytokine production GO:0001819 174 0.015
cellular response to dna damage stimulus GO:0006974 207 0.014
regulation of t cell activation GO:0050863 170 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
negative regulation of organelle organization GO:0010639 90 0.014
lipid biosynthetic process GO:0008610 179 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
regulation of binding GO:0051098 111 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
striated muscle contraction GO:0006941 45 0.014
regulation of metal ion transport GO:0010959 106 0.014
developmental maturation GO:0021700 193 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
fertilization GO:0009566 127 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
protein targeting GO:0006605 143 0.014
regulation of secretion by cell GO:1903530 249 0.014
membrane organization GO:0061024 245 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
skeletal system development GO:0001501 356 0.014
neuron apoptotic process GO:0051402 142 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
myeloid cell differentiation GO:0030099 233 0.014
multicellular organismal signaling GO:0035637 91 0.014
endomembrane system organization GO:0010256 147 0.014
protein maturation GO:0051604 176 0.014
synapse organization GO:0050808 125 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
mapk cascade GO:0000165 281 0.014
neural tube development GO:0021915 160 0.014
divalent metal ion transport GO:0070838 172 0.013
meiotic cell cycle GO:0051321 122 0.013
single organismal cell cell adhesion GO:0016337 131 0.013
response to lipopolysaccharide GO:0032496 128 0.013
sulfur compound metabolic process GO:0006790 100 0.013
digestive system development GO:0055123 200 0.013
extracellular matrix organization GO:0030198 147 0.013
endocytosis GO:0006897 168 0.013
response to inorganic substance GO:0010035 96 0.013
small molecule biosynthetic process GO:0044283 132 0.013
rhythmic process GO:0048511 174 0.013
germ cell development GO:0007281 185 0.013
respiratory system development GO:0060541 190 0.013
lymphocyte differentiation GO:0030098 242 0.013
regulation of kinase activity GO:0043549 249 0.013
locomotory behavior GO:0007626 195 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
circadian rhythm GO:0007623 114 0.013
metal ion homeostasis GO:0055065 189 0.013
nitrogen compound transport GO:0071705 271 0.013
oocyte construction GO:0007308 2 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
regulation of cell migration GO:0030334 219 0.013
Human
angiogenesis GO:0001525 201 0.013
regulation of neuron death GO:1901214 134 0.013
regulation of cellular component size GO:0032535 121 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
skeletal myofibril assembly GO:0014866 4 0.013
regulation of body fluid levels GO:0050878 162 0.012
response to oxidative stress GO:0006979 123 0.012
positive regulation of cell development GO:0010720 237 0.012
negative regulation of hydrolase activity GO:0051346 71 0.012
wnt signaling pathway GO:0016055 188 0.012
cardiac muscle cell differentiation GO:0055007 69 0.012
Zebrafish
single organism nuclear import GO:1902593 95 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
regulation of blood circulation GO:1903522 93 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
cardiocyte differentiation GO:0035051 87 0.012
Zebrafish
calcium ion transport GO:0006816 159 0.012
response to oxygen levels GO:0070482 62 0.012
meiotic nuclear division GO:0007126 115 0.012
cilium morphogenesis GO:0060271 102 0.012
mitochondrion organization GO:0007005 134 0.012
positive regulation of cell death GO:0010942 224 0.012
synaptic transmission GO:0007268 329 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
positive regulation of cell activation GO:0050867 158 0.012
positive regulation of cell motility GO:2000147 116 0.012
male anatomical structure morphogenesis GO:0090598 4 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
cardiac muscle cell development GO:0055013 39 0.012
Zebrafish
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
fat cell differentiation GO:0045444 160 0.012
regulation of cell adhesion GO:0030155 154 0.012
lateral inhibition GO:0046331 1 0.012
regulation of protein complex assembly GO:0043254 83 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
dephosphorylation GO:0016311 129 0.012
nuclear import GO:0051170 95 0.012
blood vessel morphogenesis GO:0048514 285 0.012
male genitalia morphogenesis GO:0048808 4 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
regulation of proteolysis GO:0030162 164 0.011
translation GO:0006412 93 0.011
covalent chromatin modification GO:0016569 163 0.011
regulation of protein complex disassembly GO:0043244 28 0.011
apical constriction GO:0003383 4 0.011
regulation of cellular response to stress GO:0080135 159 0.011
negative regulation of kinase activity GO:0033673 81 0.011
negative regulation of transferase activity GO:0051348 85 0.011
spermatid development GO:0007286 108 0.011
cardiac cell development GO:0055006 41 0.011
Zebrafish
divalent inorganic cation homeostasis GO:0072507 138 0.011
chromatin organization GO:0006325 206 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
oocyte axis specification GO:0007309 2 0.011
single organism cell adhesion GO:0098602 156 0.011
adult behavior GO:0030534 135 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
regulation of feeding behavior GO:0060259 3 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
protein import GO:0017038 101 0.011
digestive tract development GO:0048565 190 0.011
gland development GO:0048732 330 0.011
male gamete generation GO:0048232 285 0.011
chemotaxis GO:0006935 247 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
multicellular organism growth GO:0035264 161 0.011
regulation of actin filament length GO:0030832 45 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
retina development in camera type eye GO:0060041 119 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
regulation of blood pressure GO:0008217 93 0.011
protein localization to membrane GO:0072657 108 0.011
regulation of muscle tissue development GO:1901861 97 0.011
regulation of multi organism process GO:0043900 111 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
regulation of transporter activity GO:0032409 57 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
defense response to other organism GO:0098542 197 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
muscle contraction GO:0006936 101 0.011
multi multicellular organism process GO:0044706 109 0.011
gtp metabolic process GO:0046039 144 0.011
regulation of neuron differentiation GO:0045664 281 0.011
negative regulation of cell development GO:0010721 169 0.011
positive regulation of nervous system development GO:0051962 221 0.011
regulation of defense response GO:0031347 233 0.011
b cell activation GO:0042113 161 0.010
spermatid differentiation GO:0048515 115 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
cellular protein catabolic process GO:0044257 155 0.010
regulation of protein binding GO:0043393 60 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
epithelial cell proliferation GO:0050673 174 0.010
tube formation GO:0035148 140 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
innate immune response GO:0045087 157 0.010
negative regulation of neuron apoptotic process GO:0043524 92 0.010
kidney development GO:0001822 213 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
nucleoside monophosphate catabolic process GO:0009125 59 0.010
regulation of homeostatic process GO:0032844 182 0.010
regulation of lamellipodium assembly GO:0010591 3 0.010
connective tissue development GO:0061448 179 0.010
telencephalon development GO:0021537 186 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
regulation of calcium ion transport GO:0051924 69 0.010
leukocyte proliferation GO:0070661 172 0.010
dendrite development GO:0016358 115 0.010
establishment of organelle localization GO:0051656 122 0.010
regulation of heart contraction GO:0008016 77 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010
regulation of protein transport GO:0051223 163 0.010
regulation of protein catabolic process GO:0042176 108 0.010

Nexn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.097
Human
muscular disease DOID:0080000 0 0.097
Human
disease of anatomical entity DOID:7 0 0.097
Human
muscle tissue disease DOID:66 0 0.047
Human
myopathy DOID:423 0 0.047
Human
cardiovascular system disease DOID:1287 0 0.026
Human
cardiomyopathy DOID:0050700 0 0.022
Human
heart disease DOID:114 0 0.022
Human
nervous system disease DOID:863 0 0.022
intrinsic cardiomyopathy DOID:0060036 0 0.016
Human
central nervous system disease DOID:331 0 0.013
immune system disease DOID:2914 0 0.012
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011