Mus musculus

194 known processes

Prl2c2

prolactin family 2, subfamily c, member 2

(Aliases: Plf,Plf1,MRP-1,PLF-1)

Prl2c2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.073
Mouse
neural precursor cell proliferation GO:0061351 121 0.063
regulation of microvillus assembly GO:0032534 3 0.054
angiogenesis GO:0001525 201 0.053
response to organonitrogen compound GO:0010243 246 0.048
positive regulation of cellular amine metabolic process GO:0033240 5 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
ameboidal type cell migration GO:0001667 128 0.039
positive regulation of cell projection organization GO:0031346 95 0.037
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.036
response to extracellular stimulus GO:0009991 127 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
nitrogen compound transport GO:0071705 271 0.035
rho protein signal transduction GO:0007266 32 0.035
cellular response to organonitrogen compound GO:0071417 145 0.035
cellular response to insulin stimulus GO:0032869 78 0.035
regulation of microvillus organization GO:0032530 3 0.034
purine containing compound metabolic process GO:0072521 311 0.034
stem cell proliferation GO:0072089 117 0.033
cellular response to peptide GO:1901653 92 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
defense response to other organism GO:0098542 197 0.031
multicellular organism growth GO:0035264 161 0.029
cytoplasmic transport GO:0016482 234 0.029
blood vessel morphogenesis GO:0048514 285 0.029
response to organic cyclic compound GO:0014070 198 0.029
response to oxygen levels GO:0070482 62 0.028
response to molecule of bacterial origin GO:0002237 143 0.028
regulation of cell projection organization GO:0031344 206 0.028
immune effector process GO:0002252 321 0.028
nucleotide metabolic process GO:0009117 332 0.028
regulation of cellular ketone metabolic process GO:0010565 66 0.028
nucleocytoplasmic transport GO:0006913 139 0.028
cellular ketone metabolic process GO:0042180 84 0.028
cellular response to lipid GO:0071396 145 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.026
negative regulation of endothelial cell migration GO:0010596 4 0.026
Mouse
response to nutrient levels GO:0031667 109 0.026
oxidation reduction process GO:0055114 342 0.026
stem cell differentiation GO:0048863 268 0.026
regulation of mapk cascade GO:0043408 248 0.026
response to peptide GO:1901652 136 0.026
small gtpase mediated signal transduction GO:0007264 97 0.025
ras protein signal transduction GO:0007265 77 0.025
male gamete generation GO:0048232 285 0.025
organonitrogen compound catabolic process GO:1901565 264 0.024
cellular response to hormone stimulus GO:0032870 150 0.024
positive regulation of protein modification process GO:0031401 299 0.024
protein localization to organelle GO:0033365 185 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
regulation of vasculature development GO:1901342 88 0.023
regulation of hydrolase activity GO:0051336 246 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
nucleoside metabolic process GO:0009116 246 0.023
mapk cascade GO:0000165 281 0.023
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.023
leukocyte mediated immunity GO:0002443 174 0.022
gland development GO:0048732 330 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
regulation of cellular catabolic process GO:0031329 242 0.022
protein maturation GO:0051604 176 0.022
activation of immune response GO:0002253 138 0.022
cell recognition GO:0008037 83 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
glycosyl compound metabolic process GO:1901657 246 0.021
regulation of kinase activity GO:0043549 249 0.021
cognition GO:0050890 149 0.021
response to peptide hormone GO:0043434 127 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
cell adhesion GO:0007155 329 0.021
cellular amino acid metabolic process GO:0006520 103 0.020
glycoprotein metabolic process GO:0009100 116 0.020
dna metabolic process GO:0006259 303 0.020
multicellular organismal signaling GO:0035637 91 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
positive regulation of apoptotic signaling pathway GO:2001235 95 0.019
cellular amine metabolic process GO:0044106 44 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
amide transport GO:0042886 138 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
aromatic compound catabolic process GO:0019439 286 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
positive regulation of cell motility GO:2000147 116 0.019
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.019
carbohydrate metabolic process GO:0005975 230 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
lipid biosynthetic process GO:0008610 179 0.019
cellular chemical homeostasis GO:0055082 215 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.019
regulation of hormone levels GO:0010817 211 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
nucleotide catabolic process GO:0009166 217 0.019
inflammatory response GO:0006954 244 0.018
ossification GO:0001503 216 0.018
sensory perception GO:0007600 245 0.018
macromolecule methylation GO:0043414 120 0.018
epithelium migration GO:0090132 63 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
purine containing compound catabolic process GO:0072523 213 0.018
response to decreased oxygen levels GO:0036293 59 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
neuron death GO:0070997 154 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
positive regulation of cytokine production GO:0001819 174 0.018
multi multicellular organism process GO:0044706 109 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
ribonucleoside metabolic process GO:0009119 245 0.017
blood circulation GO:0008015 195 0.017
methylation GO:0032259 134 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
regulation of cell migration GO:0030334 219 0.017
cell type specific apoptotic process GO:0097285 268 0.017
protein targeting GO:0006605 143 0.017
chemotaxis GO:0006935 247 0.017
regulation of striated muscle cell differentiation GO:0051153 81 0.017
regulation of protein localization GO:0032880 231 0.017
cytokine production GO:0001816 319 0.017
membrane organization GO:0061024 245 0.017
metal ion homeostasis GO:0055065 189 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
positive regulation of nervous system development GO:0051962 221 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
cation homeostasis GO:0055080 212 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
positive regulation of cell development GO:0010720 237 0.016
striated muscle cell development GO:0055002 125 0.016
cellular response to biotic stimulus GO:0071216 92 0.016
transmission of nerve impulse GO:0019226 76 0.016
protein processing GO:0016485 163 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
response to insulin GO:0032868 100 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
apoptotic signaling pathway GO:0097190 306 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.016
nucleoside catabolic process GO:0009164 206 0.016
regulation of membrane potential GO:0042391 192 0.016
macromolecule catabolic process GO:0009057 281 0.016
transmembrane transport GO:0055085 412 0.016
immune response regulating signaling pathway GO:0002764 125 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
lung development GO:0030324 164 0.016
response to hypoxia GO:0001666 58 0.016
cellular homeostasis GO:0019725 240 0.016
action potential GO:0001508 78 0.016
response to lipopolysaccharide GO:0032496 128 0.016
protein import GO:0017038 101 0.016
fertilization GO:0009566 127 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
regulation of defense response GO:0031347 233 0.015
response to growth factor GO:0070848 198 0.015
regulation of cell activation GO:0050865 289 0.015
interferon gamma production GO:0032609 67 0.015
negative regulation of protein processing GO:0010955 79 0.015
muscle tissue development GO:0060537 308 0.015
nuclear transport GO:0051169 139 0.015
response to acid chemical GO:0001101 111 0.015
regulation of angiogenesis GO:0045765 81 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
cell activation involved in immune response GO:0002263 126 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
immune response activating signal transduction GO:0002757 116 0.015
epithelial cell development GO:0002064 159 0.015
regulation of protein maturation GO:1903317 96 0.015
protein import into nucleus GO:0006606 95 0.015
fat cell differentiation GO:0045444 160 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
cation transmembrane transport GO:0098655 266 0.015
myotube differentiation GO:0014902 105 0.015
epithelial cell migration GO:0010631 63 0.014
regulation of organelle organization GO:0033043 289 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
response to light stimulus GO:0009416 135 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
regulation of protein processing GO:0070613 96 0.014
sprouting angiogenesis GO:0002040 26 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
intracellular protein transport GO:0006886 204 0.014
b cell activation GO:0042113 161 0.014
tissue migration GO:0090130 68 0.014
response to radiation GO:0009314 165 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
positive regulation of cell death GO:0010942 224 0.014
regulation of myotube differentiation GO:0010830 62 0.014
maternal process involved in female pregnancy GO:0060135 32 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
positive regulation of cell migration GO:0030335 109 0.014
response to testosterone GO:0033574 3 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
protein methylation GO:0006479 81 0.014
purine nucleotide biosynthetic process GO:0006164 65 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
organophosphate catabolic process GO:0046434 232 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
regulation of proteolysis GO:0030162 164 0.013
single organism nuclear import GO:1902593 95 0.013
anatomical structure homeostasis GO:0060249 145 0.013
homeostasis of number of cells GO:0048872 210 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
cation transport GO:0006812 399 0.013
regulation of response to wounding GO:1903034 189 0.013
steroid metabolic process GO:0008202 119 0.013
respiratory system development GO:0060541 190 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
glucose transport GO:0015758 56 0.013
cellular response to molecule of fungal origin GO:0071226 2 0.013
germ cell development GO:0007281 185 0.013
heterocycle catabolic process GO:0046700 280 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
regulation of transferase activity GO:0051338 263 0.013
skeletal muscle organ development GO:0060538 163 0.013
protein alkylation GO:0008213 81 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
cellular response to acid chemical GO:0071229 68 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
endocytosis GO:0006897 168 0.013
cell maturation GO:0048469 127 0.013
single organism cell adhesion GO:0098602 156 0.013
circulatory system process GO:0003013 197 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
forebrain development GO:0030900 302 0.013
regulation of protein catabolic process GO:0042176 108 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
amine metabolic process GO:0009308 45 0.013
adult behavior GO:0030534 135 0.012
ear development GO:0043583 200 0.012
negative regulation of neuron death GO:1901215 98 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
muscle fiber development GO:0048747 76 0.012
stem cell development GO:0048864 219 0.012
muscle cell differentiation GO:0042692 261 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
dna repair GO:0006281 107 0.012
positive regulation of growth GO:0045927 104 0.012
defense response to bacterium GO:0042742 119 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
regulation of body fluid levels GO:0050878 162 0.012
negative regulation of proteolysis GO:0045861 74 0.012
regulation of cell projection assembly GO:0060491 38 0.012
regulation of cytokine production GO:0001817 266 0.012
negative regulation of molecular function GO:0044092 258 0.012
regulation of cell adhesion GO:0030155 154 0.012
compound eye development GO:0048749 1 0.012
blood vessel endothelial cell migration GO:0043534 23 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
regulation of endocytosis GO:0030100 69 0.012
t cell activation GO:0042110 289 0.012
learning or memory GO:0007611 148 0.012
regulation of neuron differentiation GO:0045664 281 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
negative regulation of protein maturation GO:1903318 79 0.011
positive regulation of cell activation GO:0050867 158 0.011
regulation of system process GO:0044057 200 0.011
response to oxidative stress GO:0006979 123 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
leukocyte chemotaxis GO:0030595 69 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
positive regulation of angiogenesis GO:0045766 46 0.011
protein glycosylation GO:0006486 55 0.011
organelle fission GO:0048285 170 0.011
positive regulation of kinase activity GO:0033674 155 0.011
protein catabolic process GO:0030163 221 0.011
binding of sperm to zona pellucida GO:0007339 34 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
sequestering of calcium ion GO:0051208 18 0.011
tissue homeostasis GO:0001894 115 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
dephosphorylation GO:0016311 129 0.011
muscle cell development GO:0055001 133 0.011
epithelial cell proliferation GO:0050673 174 0.011
response to inorganic substance GO:0010035 96 0.011
cell growth GO:0016049 130 0.011
myeloid cell differentiation GO:0030099 233 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
innate immune response GO:0045087 157 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
peptidyl amino acid modification GO:0018193 336 0.011
glycosylation GO:0070085 62 0.011
response to amino acid GO:0043200 37 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
macromolecule glycosylation GO:0043413 55 0.011
leukocyte activation involved in immune response GO:0002366 126 0.010
regulation of homeostatic process GO:0032844 182 0.010
nuclear division GO:0000280 158 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
parental behavior GO:0060746 11 0.010
positive regulation of secretion GO:0051047 130 0.010
negative regulation of immune system process GO:0002683 209 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
leukocyte differentiation GO:0002521 342 0.010
peptide hormone secretion GO:0030072 109 0.010
regulation of interferon gamma production GO:0032649 57 0.010
lipid catabolic process GO:0016042 69 0.010

Prl2c2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.017
disease of anatomical entity DOID:7 0 0.017
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
central nervous system disease DOID:331 0 0.011