Mus musculus

59 known processes

Impdh2

inosine 5'-phosphate dehydrogenase 2

(Aliases: IMPD)

Impdh2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic cyclic compound catabolic process GO:1901361 295 0.521
nucleoside metabolic process GO:0009116 246 0.466
dna dealkylation GO:0035510 11 0.441
heterocycle catabolic process GO:0046700 280 0.348
ribonucleoside triphosphate metabolic process GO:0009199 220 0.258
ribonucleoside metabolic process GO:0009119 245 0.227
dna metabolic process GO:0006259 303 0.225
mrna splicing via spliceosome GO:0000398 43 0.213
ribonucleotide metabolic process GO:0009259 291 0.185
cellular nitrogen compound catabolic process GO:0044270 280 0.182
development of primary sexual characteristics GO:0045137 143 0.182
purine containing compound metabolic process GO:0072521 311 0.171
aromatic compound catabolic process GO:0019439 286 0.169
spindle assembly involved in mitosis GO:0090307 4 0.167
nucleoside triphosphate metabolic process GO:0009141 230 0.166
purine ribonucleotide metabolic process GO:0009150 290 0.165
nucleotide catabolic process GO:0009166 217 0.156
nucleotide metabolic process GO:0009117 332 0.153
ribonucleotide catabolic process GO:0009261 208 0.152
dna repair GO:0006281 107 0.152
mrna metabolic process GO:0016071 84 0.148
glycosyl compound metabolic process GO:1901657 246 0.140
cellular response to dna damage stimulus GO:0006974 207 0.138
germ cell development GO:0007281 185 0.137
translation GO:0006412 93 0.128
mrna processing GO:0006397 63 0.127
microtubule based process GO:0007017 236 0.123
ribonucleoprotein complex subunit organization GO:0071826 28 0.115
nucleobase containing small molecule metabolic process GO:0055086 352 0.111
ribose phosphate metabolic process GO:0019693 291 0.110
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.105
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.103
embryonic organ morphogenesis GO:0048562 276 0.102
ribonucleoside catabolic process GO:0042454 206 0.102
fertilization GO:0009566 127 0.090
rna splicing GO:0008380 54 0.090
cytoplasmic transport GO:0016482 234 0.087
macromolecule methylation GO:0043414 120 0.082
rna splicing via transesterification reactions GO:0000375 43 0.082
organophosphate catabolic process GO:0046434 232 0.080
organelle fission GO:0048285 170 0.077
posttranscriptional regulation of gene expression GO:0010608 155 0.076
rna processing GO:0006396 105 0.073
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.071
nucleoside phosphate metabolic process GO:0006753 338 0.066
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.066
purine ribonucleoside metabolic process GO:0046128 241 0.064
mitotic cell cycle process GO:1903047 159 0.063
purine nucleoside triphosphate metabolic process GO:0009144 226 0.063
nucleoside triphosphate catabolic process GO:0009143 205 0.062
positive regulation of protein modification process GO:0031401 299 0.061
endocytosis GO:0006897 168 0.061
Fly
purine nucleoside catabolic process GO:0006152 205 0.060
mitotic cell cycle GO:0000278 195 0.058
gonad development GO:0008406 141 0.057
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.056
maturation of ssu rrna GO:0030490 1 0.056
toxin transport GO:1901998 38 0.054
transcription coupled nucleotide excision repair GO:0006283 2 0.053
regulation of mitotic cell cycle GO:0007346 126 0.053
atp catabolic process GO:0006200 55 0.052
nucleoside catabolic process GO:0009164 206 0.052
microtubule cytoskeleton organization GO:0000226 157 0.051
atp metabolic process GO:0046034 75 0.050
purine nucleotide metabolic process GO:0006163 302 0.049
regulation of cellular response to stress GO:0080135 159 0.049
regulation of nucleoside metabolic process GO:0009118 130 0.048
hematopoietic progenitor cell differentiation GO:0002244 143 0.048
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
translational initiation GO:0006413 24 0.047
binding of sperm to zona pellucida GO:0007339 34 0.047
purine containing compound catabolic process GO:0072523 213 0.046
carbohydrate derivative catabolic process GO:1901136 231 0.046
purine nucleoside monophosphate metabolic process GO:0009126 81 0.046
regulation of nucleotide metabolic process GO:0006140 169 0.045
chromatin organization GO:0006325 206 0.045
i kappab kinase nf kappab signaling GO:0007249 85 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.043
nucleoside phosphate catabolic process GO:1901292 222 0.043
snorna metabolic process GO:0016074 1 0.042
cell cell recognition GO:0009988 44 0.042
purine nucleoside triphosphate catabolic process GO:0009146 203 0.041
regulation of mitotic cell cycle phase transition GO:1901990 73 0.041
organelle assembly GO:0070925 177 0.040
purine ribonucleoside catabolic process GO:0046130 205 0.040
nucleoside monophosphate metabolic process GO:0009123 85 0.040
purine nucleoside metabolic process GO:0042278 241 0.036
mrna 3 end processing GO:0031124 16 0.036
sperm egg recognition GO:0035036 37 0.036
regulation of purine nucleotide catabolic process GO:0033121 122 0.035
dna demethylation GO:0080111 10 0.035
interspecies interaction between organisms GO:0044419 83 0.035
regulation of membrane potential GO:0042391 192 0.034
epithelial cell proliferation GO:0050673 174 0.033
negative regulation of cell proliferation GO:0008285 296 0.033
regulation of protein localization GO:0032880 231 0.032
methylation GO:0032259 134 0.032
positive regulation of hydrolase activity GO:0051345 148 0.031
ion transmembrane transport GO:0034220 361 0.031
cellular amine metabolic process GO:0044106 44 0.030
positive regulation of rna splicing GO:0033120 12 0.030
receptor mediated endocytosis GO:0006898 51 0.030
genetic imprinting GO:0071514 27 0.029
rna catabolic process GO:0006401 29 0.029
ncrna processing GO:0034470 26 0.029
cytoplasmic translational initiation GO:0002183 3 0.029
cellular response to cytokine stimulus GO:0071345 189 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
rna 3 end processing GO:0031123 20 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
amine metabolic process GO:0009308 45 0.026
regulation of dna damage checkpoint GO:2000001 3 0.026
generation of precursor metabolites and energy GO:0006091 103 0.025
purine nucleotide biosynthetic process GO:0006164 65 0.025
base excision repair GO:0006284 9 0.025
leukocyte migration GO:0050900 124 0.025
intracellular protein transport GO:0006886 204 0.024
regulation of organelle organization GO:0033043 289 0.024
demethylation GO:0070988 23 0.024
regulation of intracellular protein transport GO:0033157 82 0.024
cellular homeostasis GO:0019725 240 0.024
oocyte anterior posterior axis specification GO:0007314 2 0.023
cation transport GO:0006812 399 0.023
negative regulation of translation GO:0017148 22 0.023
regulation of feeding behavior GO:0060259 3 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
negative regulation of mrna splicing via spliceosome GO:0048025 12 0.023
dna modification GO:0006304 50 0.023
placenta development GO:0001890 140 0.023
negative regulation of molecular function GO:0044092 258 0.022
gland development GO:0048732 330 0.022
ribose phosphate biosynthetic process GO:0046390 59 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
positive regulation of intracellular transport GO:0032388 70 0.022
single fertilization GO:0007338 82 0.022
transmembrane transport GO:0055085 412 0.022
cellular ketone metabolic process GO:0042180 84 0.022
positive regulation of translation GO:0045727 19 0.022
cation homeostasis GO:0055080 212 0.021
purine nucleotide catabolic process GO:0006195 211 0.020
dna catabolic process GO:0006308 19 0.020
regulation of cell cycle GO:0051726 281 0.020
regulation of organ morphogenesis GO:2000027 144 0.019
regulation of response to dna damage stimulus GO:2001020 34 0.019
chromatin modification GO:0016568 187 0.019
genitalia development GO:0048806 37 0.019
ribonucleoside monophosphate catabolic process GO:0009158 57 0.019
ossification GO:0001503 216 0.018
female gamete generation GO:0007292 74 0.018
positive regulation of organelle organization GO:0010638 128 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
leukocyte apoptotic process GO:0071887 71 0.018
nuclear export GO:0051168 34 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
nuclear division GO:0000280 158 0.017
regulation of intracellular transport GO:0032386 159 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
protein localization to organelle GO:0033365 185 0.017
leukocyte chemotaxis GO:0030595 69 0.017
dna conformation change GO:0071103 37 0.016
regulation of rna splicing GO:0043484 37 0.016
regulation of mrna processing GO:0050684 41 0.016
regulation of hydrolase activity GO:0051336 246 0.016
body morphogenesis GO:0010171 45 0.016
sensory organ morphogenesis GO:0090596 242 0.016
glial cell differentiation GO:0010001 131 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
regulation of kinase activity GO:0043549 249 0.015
cation transmembrane transport GO:0098655 266 0.015
negative regulation of cell cycle GO:0045786 123 0.015
cell recognition GO:0008037 83 0.015
negative regulation of kinase activity GO:0033673 81 0.015
macromolecule catabolic process GO:0009057 281 0.015
regulation of mrna splicing via spliceosome GO:0048024 32 0.015
regulation of mrna metabolic process GO:1903311 43 0.015
regulation of translation GO:0006417 71 0.014
camera type eye development GO:0043010 266 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.014
segmentation GO:0035282 93 0.014
mitotic nuclear division GO:0007067 48 0.014
cell chemotaxis GO:0060326 81 0.014
stem cell differentiation GO:0048863 268 0.014
regulation of cell cycle process GO:0010564 160 0.014
positive regulation of cell death GO:0010942 224 0.014
ras protein signal transduction GO:0007265 77 0.013
oocyte construction GO:0007308 2 0.013
gtp catabolic process GO:0006184 143 0.013
gtp metabolic process GO:0046039 144 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
axon guidance GO:0007411 141 0.013
Fly
regulation of protein binding GO:0043393 60 0.013
regulation of ion transport GO:0043269 215 0.013
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.013
negative regulation of mrna metabolic process GO:1903312 13 0.013
regulation of gtp catabolic process GO:0033124 113 0.012
pharynx development GO:0060465 1 0.012
respiratory system development GO:0060541 190 0.012
chemotaxis GO:0006935 247 0.012
Fly
organonitrogen compound biosynthetic process GO:1901566 192 0.012
myeloid leukocyte migration GO:0097529 57 0.012
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.012
nitrogen compound transport GO:0071705 271 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
peptidyl amino acid modification GO:0018193 336 0.011
regulation of protein kinase activity GO:0045859 232 0.011
response to light stimulus GO:0009416 135 0.011
peptidyl lysine modification GO:0018205 77 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
blood circulation GO:0008015 195 0.011
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.011
positive regulation of dna repair GO:0045739 3 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.011
viral process GO:0016032 41 0.011
female sex differentiation GO:0046660 84 0.011
cellular response to lipid GO:0071396 145 0.010
organonitrogen compound catabolic process GO:1901565 264 0.010
viral life cycle GO:0019058 36 0.010
protein localization to nucleus GO:0034504 121 0.010
negative regulation of rna splicing GO:0033119 12 0.010
positive regulation of cell cycle phase transition GO:1901989 17 0.010
pole plasm assembly GO:0007315 2 0.010
ribonucleotide biosynthetic process GO:0009260 59 0.010
histone modification GO:0016570 159 0.010
leukocyte differentiation GO:0002521 342 0.010
molting cycle GO:0042303 90 0.010
positive regulation of programmed cell death GO:0043068 218 0.010

Impdh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.016
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
neurodegenerative disease DOID:1289 0 0.011