Mus musculus

89 known processes

Trp53inp1

transformation related protein 53 inducible nuclear protein 1

(Aliases: SIP,SIP27,2700057G22Rik,Teap,SIP18,Stinp)

Trp53inp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.100
regulation of cellular ketone metabolic process GO:0010565 66 0.077
macromolecule catabolic process GO:0009057 281 0.070
cellular ketone metabolic process GO:0042180 84 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
regulation of cellular amine metabolic process GO:0033238 20 0.057
amine metabolic process GO:0009308 45 0.057
cellular amine metabolic process GO:0044106 44 0.056
apoptotic signaling pathway GO:0097190 306 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.053
cation transport GO:0006812 399 0.050
protein catabolic process GO:0030163 221 0.048
cellular amino acid metabolic process GO:0006520 103 0.046
protein ubiquitination GO:0016567 171 0.043
cellular macromolecule catabolic process GO:0044265 206 0.042
protein modification by small protein conjugation GO:0032446 187 0.041
positive regulation of cellular amine metabolic process GO:0033240 5 0.041
response to organonitrogen compound GO:0010243 246 0.041
transmembrane transport GO:0055085 412 0.040
organic cyclic compound catabolic process GO:1901361 295 0.037
protein modification by small protein conjugation or removal GO:0070647 207 0.037
reactive oxygen species metabolic process GO:0072593 84 0.035
cell type specific apoptotic process GO:0097285 268 0.035
negative regulation of molecular function GO:0044092 258 0.033
cytokine production GO:0001816 319 0.032
cation transmembrane transport GO:0098655 266 0.031
response to light stimulus GO:0009416 135 0.031
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
heterocycle catabolic process GO:0046700 280 0.031
intrinsic apoptotic signaling pathway GO:0097193 132 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
positive regulation of cell death GO:0010942 224 0.030
spermatogenesis GO:0007283 284 0.030
carbohydrate metabolic process GO:0005975 230 0.030
ribose phosphate metabolic process GO:0019693 291 0.029
macromolecule methylation GO:0043414 120 0.029
response to endoplasmic reticulum stress GO:0034976 53 0.029
cellular protein catabolic process GO:0044257 155 0.029
regulation of reactive oxygen species metabolic process GO:2000377 40 0.029
actin cytoskeleton organization GO:0030036 220 0.028
methylation GO:0032259 134 0.028
g protein coupled receptor signaling pathway GO:0007186 243 0.028
negative regulation of cell proliferation GO:0008285 296 0.027
ion transmembrane transport GO:0034220 361 0.027
ubiquitin dependent protein catabolic process GO:0006511 129 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
ras protein signal transduction GO:0007265 77 0.027
aromatic compound catabolic process GO:0019439 286 0.027
negative regulation of protein metabolic process GO:0051248 282 0.026
multicellular organism growth GO:0035264 161 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
Human
positive regulation of apoptotic process GO:0043065 217 0.026
maintenance of location GO:0051235 89 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
regulation of cellular response to stress GO:0080135 159 0.025
positive regulation of protein modification process GO:0031401 299 0.025
positive regulation of programmed cell death GO:0043068 218 0.025
response to oxidative stress GO:0006979 123 0.025
response to acid chemical GO:0001101 111 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
cellular response to lipid GO:0071396 145 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
male gamete generation GO:0048232 285 0.025
regulation of membrane potential GO:0042391 192 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
regulation of cell activation GO:0050865 289 0.024
regulation of organelle organization GO:0033043 289 0.024
lipid biosynthetic process GO:0008610 179 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
mitochondrion organization GO:0007005 134 0.023
regulation of cell cycle GO:0051726 281 0.023
negative regulation of immune system process GO:0002683 209 0.023
nucleotide metabolic process GO:0009117 332 0.023
t cell activation GO:0042110 289 0.023
regulation of cell migration GO:0030334 219 0.023
response to organic cyclic compound GO:0014070 198 0.023
purine containing compound metabolic process GO:0072521 311 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
dna repair GO:0006281 107 0.022
organophosphate biosynthetic process GO:0090407 122 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
dna metabolic process GO:0006259 303 0.022
cytoplasmic transport GO:0016482 234 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
regulation of protein localization GO:0032880 231 0.022
nitrogen compound transport GO:0071705 271 0.022
rna processing GO:0006396 105 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
cellular lipid metabolic process GO:0044255 323 0.021
protein localization to nucleus GO:0034504 121 0.021
skin development GO:0043588 220 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
cognition GO:0050890 149 0.021
response to radiation GO:0009314 165 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
immune effector process GO:0002252 321 0.020
protein localization to organelle GO:0033365 185 0.020
germ cell development GO:0007281 185 0.020
endocytosis GO:0006897 168 0.020
nucleoside metabolic process GO:0009116 246 0.020
gland development GO:0048732 330 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
regulation of hydrolase activity GO:0051336 246 0.020
regulation of t cell activation GO:0050863 170 0.020
negative regulation of cell activation GO:0050866 111 0.020
mitotic cell cycle GO:0000278 195 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.019
rho protein signal transduction GO:0007266 32 0.019
regulation of protein catabolic process GO:0042176 108 0.019
glycoprotein metabolic process GO:0009100 116 0.019
urogenital system development GO:0001655 261 0.019
sensory perception GO:0007600 245 0.019
negative regulation of cell cycle GO:0045786 123 0.019
cellular homeostasis GO:0019725 240 0.019
cation homeostasis GO:0055080 212 0.019
muscle system process GO:0003012 141 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
Human
muscle tissue development GO:0060537 308 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
blood circulation GO:0008015 195 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
myeloid cell differentiation GO:0030099 233 0.018
sensory organ morphogenesis GO:0090596 242 0.018
retrograde transport endosome to golgi GO:0042147 2 0.018
leukocyte differentiation GO:0002521 342 0.018
positive regulation of protein catabolic process GO:0045732 60 0.018
cellular protein complex assembly GO:0043623 116 0.018
nucleotide catabolic process GO:0009166 217 0.018
regulation of ion transport GO:0043269 215 0.018
regionalization GO:0003002 337 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
cellular response to organic cyclic compound GO:0071407 87 0.018
multicellular organismal signaling GO:0035637 91 0.018
ossification GO:0001503 216 0.018
respiratory system development GO:0060541 190 0.018
respiratory tube development GO:0030323 167 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
regulation of lymphocyte activation GO:0051249 240 0.017
cellular response to extracellular stimulus GO:0031668 81 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
forebrain development GO:0030900 302 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.017
action potential GO:0001508 78 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
response to peptide hormone GO:0043434 127 0.017
homeostasis of number of cells GO:0048872 210 0.017
cell adhesion GO:0007155 329 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
hexose metabolic process GO:0019318 98 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
organophosphate catabolic process GO:0046434 232 0.016
neuronal action potential GO:0019228 54 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
regulation of feeding behavior GO:0060259 3 0.016
peptidyl amino acid modification GO:0018193 336 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
innate immune response GO:0045087 157 0.016
membrane organization GO:0061024 245 0.016
response to nutrient levels GO:0031667 109 0.016
nucleoside catabolic process GO:0009164 206 0.016
divalent metal ion transport GO:0070838 172 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
camera type eye development GO:0043010 266 0.016
glycerolipid metabolic process GO:0046486 122 0.016
divalent inorganic cation transport GO:0072511 178 0.016
cytokine mediated signaling pathway GO:0019221 115 0.016
regulation of cytokine production GO:0001817 266 0.016
regulation of cell motility GO:2000145 236 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
gene silencing GO:0016458 38 0.016
positive regulation of nervous system development GO:0051962 221 0.015
regulation of kinase activity GO:0043549 249 0.015
reactive nitrogen species metabolic process GO:2001057 0 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
response to oxygen levels GO:0070482 62 0.015
pharynx development GO:0060465 1 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
immune response activating signal transduction GO:0002757 116 0.015
lung development GO:0030324 164 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
regulation of transferase activity GO:0051338 263 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
transmission of nerve impulse GO:0019226 76 0.015
fat cell differentiation GO:0045444 160 0.015
regulation of intracellular transport GO:0032386 159 0.015
muscle cell differentiation GO:0042692 261 0.015
intracellular protein transport GO:0006886 204 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
response to reactive oxygen species GO:0000302 56 0.015
lipid localization GO:0010876 126 0.014
b cell activation GO:0042113 161 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
activation of immune response GO:0002253 138 0.014
negative regulation of ossification GO:0030279 49 0.014
leukocyte proliferation GO:0070661 172 0.014
mitotic cell cycle process GO:1903047 159 0.014
regulation of cell adhesion GO:0030155 154 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
lymphocyte proliferation GO:0046651 164 0.014
organic anion transport GO:0015711 137 0.014
calcium ion transport GO:0006816 159 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
neuron death GO:0070997 154 0.014
regulation of protein kinase activity GO:0045859 232 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
kidney development GO:0001822 213 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
chromatin organization GO:0006325 206 0.014
protein maturation GO:0051604 176 0.014
response to extracellular stimulus GO:0009991 127 0.014
organelle localization GO:0051640 179 0.014
positive regulation of hydrolase activity GO:0051345 148 0.013
positive regulation of cytokine production GO:0001819 174 0.013
nuclear transport GO:0051169 139 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
locomotory behavior GO:0007626 195 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
regulation of glucose metabolic process GO:0010906 60 0.013
metal ion homeostasis GO:0055065 189 0.013
negative regulation of mitotic cell cycle GO:0045930 58 0.013
tube formation GO:0035148 140 0.013
dendrite development GO:0016358 115 0.013
organelle fission GO:0048285 170 0.013
calcium ion homeostasis GO:0055074 127 0.013
compound eye development GO:0048749 1 0.013
positive regulation of organelle organization GO:0010638 128 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
response to topologically incorrect protein GO:0035966 25 0.013
regulation of secretion GO:0051046 274 0.013
renal system development GO:0072001 225 0.013
potassium ion transport GO:0006813 52 0.013
limb development GO:0060173 166 0.013
response to inorganic substance GO:0010035 96 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
small molecule biosynthetic process GO:0044283 132 0.013
t cell differentiation GO:0030217 174 0.013
neural tube formation GO:0001841 108 0.013
protein autophosphorylation GO:0046777 61 0.013
purine containing compound catabolic process GO:0072523 213 0.013
spermatid differentiation GO:0048515 115 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
mapk cascade GO:0000165 281 0.013
stem cell differentiation GO:0048863 268 0.013
cellular response to nutrient levels GO:0031669 64 0.013
protein methylation GO:0006479 81 0.013
monosaccharide metabolic process GO:0005996 106 0.013
endomembrane system organization GO:0010256 147 0.013
epithelial tube formation GO:0072175 130 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
appendage development GO:0048736 166 0.013
cell activation involved in immune response GO:0002263 126 0.012
neuron apoptotic process GO:0051402 142 0.012
cellular chemical homeostasis GO:0055082 215 0.012
protein targeting GO:0006605 143 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
dephosphorylation GO:0016311 129 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
oxidation reduction process GO:0055114 342 0.012
cell substrate adhesion GO:0031589 130 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
protein alkylation GO:0008213 81 0.012
protein processing GO:0016485 163 0.012
regulation of mapk cascade GO:0043408 248 0.012
mrna metabolic process GO:0016071 84 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
cellular response to starvation GO:0009267 57 0.012
regulation of protein transport GO:0051223 163 0.012
rhythmic process GO:0048511 174 0.012
cellular ion homeostasis GO:0006873 165 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
response to insulin GO:0032868 100 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
regulation of carbohydrate metabolic process GO:0006109 75 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
regulation of anatomical structure size GO:0090066 178 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
development of primary sexual characteristics GO:0045137 143 0.012
cellular response to external stimulus GO:0071496 88 0.012
nuclear division GO:0000280 158 0.012
myosin filament assembly GO:0031034 2 0.012
digestive system development GO:0055123 200 0.012
sodium ion transport GO:0006814 73 0.012
response to starvation GO:0042594 65 0.012
developmental maturation GO:0021700 193 0.012
regulation of neuron differentiation GO:0045664 281 0.012
lateral inhibition GO:0046331 1 0.011
regulation of body fluid levels GO:0050878 162 0.011
primary neural tube formation GO:0014020 95 0.011
response to lipopolysaccharide GO:0032496 128 0.011
skeletal system development GO:0001501 356 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
regulation of secretion by cell GO:1903530 249 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
regulation of multi organism process GO:0043900 111 0.011
peptide transport GO:0015833 133 0.011
protein import GO:0017038 101 0.011
lymphocyte differentiation GO:0030098 242 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
regulation of system process GO:0044057 200 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
regulation of hormone levels GO:0010817 211 0.011
connective tissue development GO:0061448 179 0.011
extracellular structure organization GO:0043062 148 0.011
epidermis development GO:0008544 187 0.011
regulation of ossification GO:0030278 112 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
glucose metabolic process GO:0006006 92 0.011
regulation of neuron death GO:1901214 134 0.011
translation GO:0006412 93 0.011
striated muscle tissue development GO:0014706 293 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
cellular response to topologically incorrect protein GO:0035967 25 0.011
viral gene expression GO:0019080 3 0.011
angiogenesis GO:0001525 201 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
anion transport GO:0006820 177 0.011
regulation of adaptive immune response GO:0002819 90 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
single organism nuclear import GO:1902593 95 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
axonogenesis GO:0007409 274 0.011
multi multicellular organism process GO:0044706 109 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
stem cell development GO:0048864 219 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
cellular response to steroid hormone stimulus GO:0071383 33 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
carbohydrate homeostasis GO:0033500 128 0.011
negative regulation of t cell activation GO:0050868 65 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
actin filament organization GO:0007015 113 0.010
blood coagulation GO:0007596 76 0.010
cellular response to peptide GO:1901653 92 0.010
oocyte axis specification GO:0007309 2 0.010
regulation of cell projection organization GO:0031344 206 0.010
rna splicing GO:0008380 54 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
regulation of defense response GO:0031347 233 0.010
mitochondrion distribution GO:0048311 4 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
regulation of proteolysis GO:0030162 164 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
regulation of cell cycle process GO:0010564 160 0.010
positive regulation of nucleoside metabolic process GO:0045979 91 0.010
tube closure GO:0060606 91 0.010
positive regulation of cell development GO:0010720 237 0.010
response to steroid hormone GO:0048545 56 0.010
microtubule based process GO:0007017 236 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
skeletal muscle organ development GO:0060538 163 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
muscle contraction GO:0006936 101 0.010
regulation of purine nucleotide catabolic process GO:0033121 122 0.010

Trp53inp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.026
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
inherited metabolic disorder DOID:655 0 0.017
organ system cancer DOID:0050686 0 0.017
immune system disease DOID:2914 0 0.011
disease of anatomical entity DOID:7 0 0.011
bone disease DOID:0080001 0 0.010
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010
nervous system disease DOID:863 0 0.010